Mon.Aug 26, 2024

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Matching dinosaur footprints found on opposite sides of the Atlantic Ocean

Science Daily: Pharmacology News

An international team of paleontologists has found matching sets of Early Cretaceous dinosaur footprints on what are now two different continents.

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An Alzheimer's Drug May Also Slow Lewy Body Dementia

Drugs.com

MONDAY, Aug. 24, 2024 -- A type of drug used to treat Alzheimer’s disease appears to slow the progression of Lewy body dementia, the brain disease that afflicted comedian Robin Williams prior to his suicide.Cholinesterase inhibitors prevent the b.

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Tome Biosciences to lay off over 100 employees

BioPharma Drive: Drug Pricing

The buzzy startup, which had raised over $200 million in venture funding, is letting go of much of its workforce, according to a state regulatory notice.

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Looking for clues about your biological age? Your grandparents' education may offer some insight.

Science Daily: Pharmacology News

Eating well, exercising and attending regular doctor appointments can support a long healthy life, but a new study identified one possible factor beyond our control: whether you had a grandparent who went to college.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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DEA To Announce Hearing on Proposed Marijuana Rescheduling

FDA Law Blog: Biosimilars

By Larry K. Houck — Who says nothing happens in Washington, D.C., in August? The Drug Enforcement Administration (“DEA”) will announce Thursday in the Federal Register that it will hold a hearing on the proposed rescheduling of marijuana to schedule III at DEA Headquarters in Arlington, Virginia on December 2, 2024. DEA received over 43,500 public comments in response to the agency’s Notice of Proposed Rulemaking in the Federal Register on May 21, 2024.

Drugs 104
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Why children can't pay attention to the task at hand

Science Daily: Pharmacology News

Scientists have learned that children find it hard to focus on a task, and often take in information that won't help them complete their assignment. But the question is, why? In a new study, researchers found that this 'distributed attention' wasn't because children's brains weren't mature enough to understand the task or pay attention, and it wasn't because they were easily distracted and lacked the control to focus.

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More Trending

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First low frequency search for alien technology in distant galaxies

Science Daily: Pharmacology News

Researchers have announced a groundbreaking study using the Murchison Widefield Array (MWA) in Western Australia. The research is the first to search for signs of alien technology in galaxies beyond our own, focusing on low radio frequencies (100 MHz). This new approach looks at distant galaxies, making it one of the most detailed searches for super civilizations -- those more advanced than ours.

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Heat-Related Deaths Keep Rising for Americans

Drugs.com

MONDAY, Aug. 26, 2024 -- Reversing a prior downward trend, searing summers have caused a sharp uptick in the numbers of Americans who die from heat-related causes, new data shows.A look at U.S. Centers for Disease Control and Prevention deaths data.

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Early galaxies were not too big for their britches after all

Science Daily: Pharmacology News

According to a new study, some of the earliest galaxies observed with the James Webb Space Telescope are in fact much less massive than they first appeared. Black holes in some of these galaxies make them appear much brighter and bigger than they really are. This helps resolve the debate over whether the size of early galaxies requires a revision of the standard model of cosmology.

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Dr. Anthony Fauci Recovering at Home After Being Hospitalized With West Nile Virus

Drugs.com

MONDAY, Aug. 26, 2024 -- Dr. Anthony Fauci, who helped millions of Americans navigate the health challenges of the pandemic, is recovering at home after being hospitalized for a West Nile infection.Fauci should make a full recovery, a spokesperson.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Day Zero Antivirals for Future Pandemics

Codon

Brian Wang (co-founder of the nonprofit Panoplia Laboratories ) outlines his approach to making broad-spectrum antivirals. He also explains how they could be used to combat pandemics on “day zero,” well before vaccines are developed. Ebola tore through Western Africa in 2014, killing an estimated 11,325 people in two years. After the outbreak ended, it took another three years for the first Ebola vaccine by Merck to be approved.

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Mosquitos Have Another Way to Find You: Body Heat

Drugs.com

MONDAY, Aug. 26, 2024 -- Body heat is a powerful means by which mosquitos find human beings to bite, a new study shows.Mosquitos were twice as drawn to a target in a laboratory if the source emitted heat roughly the temperature of human skin as.

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Preventing counterfeiting by adding dye to liquid crystals to create uncrackable coded tags

Science Daily: Pharmacology News

A research group has developed an innovative approach to creating anti-counterfeiting labels for high-value goods. Their findings enhance the security of the currently used cholesteric liquid crystals (CLCs) by adding fluorescent dyes to produce florescent CLCs (FCLCs). Using this unique technology, the group created unique labels with almost impossible-to-counterfeit security features.

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U.S. Will Offer Free COVID Tests By Mail by Late September

Drugs.com

MONDAY, Aug. 26, 2024 -- As a summer surge in COVID cases begins to ebb and Americans brace themselves for yet another wave of infections this winter, more free COVID tests will soon be available to all, federal health officials announced.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Versant’s Jerel Davis on build-to-buy deals and pharma investment

BioPharma Drive: Drug Pricing

Build-to-buy arrangements can give pharmaceutical companies an option to acquire a startup’s assets later, as with Novartis’ deal with the Versant-backed Borealis Biosciences.

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Trans Kids More Often Turn to Teachers Than Parents for Help

Drugs.com

MONDAY, Aug. 26, 2024 -- Troubled transgender students are more likely to turn to school staff than their own parents for support, a new study finds.Trans teens feeling depressed and anxious are 74% less likely to seek help from parents than from.

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Aminomethyl Salicylaldehydes Lock onto a Surface Lysine by Forming an Extended Intramolecular Hydrogen Bond Network

Covalent Modifiers

Jacqueline Weaver, Gregory B. Craven, Linh Tram, Hao Chen, and Jack Taunton Journal of the American Chemical Society 2024 DOI: 10.1021/jacs.4c04314 The development of electrophilic ligands that rapidly modify specific lysine residues remains a major challenge. Salicylaldehyde-based inhibitors have been reported to form stable imine adducts with the catalytic lysine of protein kinases.

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Americans Are Moving Away From Polluted Areas -- If They Can Afford To

Drugs.com

MONDAY, Aug. 26, 2024 -- Americans of means are fleeing heavily polluted places in the United States for cleaner locales, a new study has found.Pollution levels are a factor in families’ decision to move within the United States, but only richer h.

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What microscopic fossilized shells tell us about ancient climate change

Science Daily: Pharmacology News

By analyzing foram shells recovered in drill cores, study led by geologists links rapid climate change that led to thermal maxima 50 million years ago to rising CO2 levels.

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Insurance Coverage Could Impact Survival of Patients After Spinal Cord Injury

Drugs.com

MONDAY, Aug. 26, 2024 -- The care of people seriously harmed by spinal cord injury can cost hundreds of thousands of dollars, and a new analysis suggests that ability to pay influences how long a patient remains on life support.In a study of more.

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Regeneron gains European approval for bispecific lymphoma drug

BioPharma Drive: Drug Pricing

Regulators in Europe granted approval based on remission rates, while the FDA sought more progress in confirmatory trials when it rejected Ordspono.

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New Approach Helps More People With Rectal Cancers Avoid Surgery

Drugs.com

MONDAY, Aug. 26, 2024 -- Giving chemo and radiation therapies before a surgery for rectal cancer can help eliminate the need for removal of the rectum altogether, a new Swedish study finds.“If the tumor disappears completely during treatment, s.

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Part two: the impact of poor data quality

Drug Target Review

In the first article in this series , published on Wednesday 14 th August, we discussed the importance that data quality plays in the effectiveness of data analyses by Machine Learning (ML) and AI. Characteristics that define data quality were listed as: Completeness Consistency Lack of bias Accuracy To understand the impact of these characteristics, one needs to appreciate the sensitivity that algorithms have to them, as well as the importance of choosing the right algorithm for the analysis be

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The Pros and Cons of Different CDMO Models

Drug Patent Watch

The pharmaceutical industry has increasingly relied on Contract Development and Manufacturing Organizations (CDMOs) to support the development and commercialization of drugs. CDMOs offer a range of services, from drug development to manufacturing, allowing pharmaceutical companies to focus on their core competencies.

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Understanding Safety Pharmacology in Human Tissues

Reprocell

This blog is the first in a series exploring the critical role of safety pharmacology in drug discovery. In this post, we delve into the importance of human tissue studies in ensuring drug safety. Stay tuned for our next installment, where we will showcase real-world case studies highlighting our innovative approaches and successes in using human tissue models for safety assessment.

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Pharma Marketing Trends: Key Takeaways from Digital Pharma East 2024

Fierce BioTech

Pharma Marketing Trends: Key Takeaways from Digital Pharma East 2024 swheeler Mon, 08/26/2024 - 14:05 Thu, 09/26/2024 - 13:00 Resource Type Webinar Stephanie Butler Promotion Start Tue, 08/27/2024 - 14:15 Promotion End Thu, 02/27/2025 - 14:15 Duration 60 minutes Did you miss the buzz at Digital Pharma East 2024? Don't worry—we've got you covered! Join us for an exclusive webinar where we'll dive into the most critical insights from the largest Digital Pharma East event ever.

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Health Consequences of Alcohol Consumption

Common Sense for Drug Policy Blog

Health Consequences of Alcohol Consumption "• The global burden of disease and injuries caused by alcohol consumption can be quantified for 31 health conditions on the basis of the available scientific evidence for the role of alcohol use in their development, occurrence and outcomes. "• Worldwide, 2.6 million deaths were attributable to alcohol consumption in 2019, representing 4.7% of all deaths in that year. "• The alcohol-attributable disease burden is heaviest among males: 2 million alcohol

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How Data and Personalization are Shaping the Future of Travel

Perficient: Drug Development

Generic travel brochures and one-size-fits-all itineraries are becoming less prevalent in today’s travel and tourism industry. Travelers crave truly unique experiences, and the industry is responding with a powerful tool: data. By harnessing the power of data and personalization, travel companies are unlocking a new era of customer engagement, satisfaction, and loyalty.

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The Crucial Role of HEK293 DNA Quantification in Biotherapeutics

Fierce BioTech

Biotherapeutics are transforming healthcare for over 350 million patients globally, tackling everything from cancer and diabetes to rare diseases. | In this episode of The Top Line, sponsored by Bio-Rad, Dipika Gurnani delves into the challenges and solutions of quantifying HEK293 DNA in biotherapeutics, a field revolutionizing healthcare for over 350 million patients worldwide.

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Maximize Your PPCC24 Experience with Perficient: Insights, Innovation, and Impact

Perficient: Drug Development

The Power Platform Community Conference 2024 in Las Vegas is fast approaching, and it’s shaping up to be one of the most impactful events of the year for anyone involved in digital transformation. Whether you’re a seasoned professional or just getting started with Microsoft’s Power Platform, this conference offers unparalleled opportunities to learn, connect, and grow.

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How biotech companies and CROs can better align to accelerate development for the most promising discoveries

BioPharma Drive: Drug Pricing

CROs are vital in supporting biotech with R&D. How can that relationship go from transactional to partnership?

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XXVII EFMC International Symposium on Medicinal Chemistry

Zobio

In person ZoBio was present in Rome for the XXVIII EFMC International Symposium on Medicinal Chemistry. The 2024 program promised to be as interesting and diverse as ever, covering significant advances in drug discovery across major therapeutic areas and it truly was. Key topics included bacterial and viral infections, as well as neurodegenerative and cardiovascular.

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Radiopharmaceutical trials: The critical role of site selection and support

BioPharma Drive: Drug Pricing

Through effective collaboration, partnerships can accelerate the development of lifesaving therapies and improve patient outcomes.

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XXVII EFMC International Symposium on Medicinal Chemistry

Zobio

In person ZoBio was present in Rome for the XXVIII EFMC International Symposium on Medicinal Chemistry. The 2024 program promised to be as interesting and diverse as ever, covering significant advances in drug discovery across major therapeutic areas and it truly was. Key topics included bacterial and viral infections, as well as neurodegenerative and cardiovascular.