Drug Discovery World
FEBRUARY 29, 2024
James Peach is the Co-Founder and CEO of Human Centric Drug Discovery (HCDD), an Oxford University spin-out improving neurology drug discovery by bringing more human data to the process. Peach shared his insight with DDW’s Megan Thomas. MT: In what ways can human data benefit neurology drug discovery? JP: At the end of the day, what matters to patients is all that matters.
Broad Institute
FEBRUARY 29, 2024
Global survey of gut microbes uncovers 18 new bacterial species and clues to antibiotic resistance By Leah Eisenstadt February 29, 2024 Breadcrumb Home Global survey of gut microbes uncovers 18 new bacterial species and clues to antibiotic resistance Researchers examined scat from hundreds of animals around the world and pinpointed genes that could fuel drug-resistant infections.
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Drug Discovery World
FEBRUARY 29, 2024
Download this guide to gain insights on the steps you can take to achieve a more sustainable lab without compromising quality or performance. Learn about: Conducting an assessment Choosing the right equipment Conserving water and reducing waste Engaging and educating your team The post Sustainability in the Lab: A Step-by-Step Guide appeared first on Drug Discovery World (DDW).
Drugs.com
FEBRUARY 29, 2024
THURSDAY, Feb. 29, 2024 -- Even if they got a COVID booster last fall, American seniors should still get a second shot this spring to best protect themselves, U.S. health officials recommended Wednesday.The latest guidance, voted on by a vaccine.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
FEBRUARY 29, 2024
A new Feature Note is now available entitled ‘ Sustainability in the Lab: A Step-by-Step Guide ‘, brought to you by PHCbi. Download the guide to gain insights on the steps you can take to achieve a more sustainable lab without compromising quality or performance. Learn about: Conducting an assessment Choosing the right equipment Conserving water and reducing waste Engaging and educating your team Download for free now.
Antidote
FEBRUARY 29, 2024
Rare Disease Day, typically observed on February 28th, will be celebrated this year on February 29th! Rare Disease Day is an awareness holiday intended to generate change for the 300 million people who are diagnosed with a rare disease worldwide, as well as their families and caregivers.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drug Target Review
FEBRUARY 29, 2024
Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? From a very young age, I was drawn to science and medicine. My interest in the field of STEM sharpened when, in my early teens, I had the chance to work in a neuro-oncology lab. This early exposure to bench science had a long-lasting impact. It propelled me to continue lab work during my undergraduate training, my medical training, and to an academic appointment in the Movement Disorders Div
Drug Discovery World
FEBRUARY 29, 2024
The stock market value of Minerva Biosciences has dropped nearly 60%, following the US Food and Drug administration (FDA) decision not to approve roluperidone for symptoms of schizophrenia. The company received a ‘Complete Response Letter’ from the FDA highlighting the clinical deficiencies in its new drug application (NDA). Although one study (MIN-101C03) demonstrated statistical significance on the primary efficacy endpoint, the FDA argued that it is insufficient on its own to establish substa
Drugs.com
FEBRUARY 29, 2024
THURSDAY, Feb. 29, 2024 -- Perhaps by reducing anxiety, a service dog can help reduce seizures in people with tough-to-treat epilepsy, a new study finds.A group of 25 study participants had an average 31% fewer seizures after months of owning a.
Drug Discovery World
FEBRUARY 29, 2024
Delivery of synthesis targets within small molecule drug discovery often involves many chemists and other collaborators, both internal and external, across multiple locations. Harnessing skills and knowledge from distributed teams can create challenges for efficiently managing the ideation process and prioritisation, assignment and delivery of agreed targets.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
FEBRUARY 29, 2024
THURSDAY, Feb. 29, 2024 -- Folks hoping to quell their anxiety would do best to use cannabis products that don’t get them high, a new clinical trial has found.The non-intoxicating marijuana compound CBD appears to help manage anxiety better than.
Drug Discovery World
FEBRUARY 29, 2024
Join DDW and Cresset for this free event ‘ Enhancing collaboration in drug discovery – a biotech perspective ’. The event will take place on 28 March at 2pm GMT / 3pm CET / 9am EST / 6am PST. Delivery of synthesis targets within small molecule drug discovery often involves many chemists and other collaborators, both internal and external, across multiple locations.
Science Daily: Pharmacology News
FEBRUARY 29, 2024
Researchers report that the Golgi ribbon, an organelle structure previously thought to be exclusive to vertebrates, is also present in animal taxa, including mollusks, earthworms, and sea urchins. The function of the Golgi ribbon is still enigmatic, but its presence in diverse animal lineages indicates that its function is not vertebrate specific, as previously thought.
Drug Discovery World
FEBRUARY 29, 2024
For Rare Disease Day 2024, Diana Spencer provides a round-up of the latest breakthroughs in the treatment of rare disease. Study reveals therapeutic potential of mRNA in rare diseases Researchers have used messenger RNA (mRNA) to create an effective therapy for a rare liver disease in preclinical studies, demonstrating the technology’s potential therapeutic use in people.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Science Daily: Pharmacology News
FEBRUARY 29, 2024
Astrobiologists have devised a novel way to determine ocean temperatures of distant worlds based on the thickness of their ice shells, effectively conducting oceanography from space.
Drugs.com
FEBRUARY 29, 2024
THURSDAY, Feb. 29, 2024 -- Ultra-processed foods can cause dozens of terrible health problems among people who eat them too often, a new review warns.Researchers linked diets high in ultra-processed foods to an increased risk of 32 separate.
Perficient: Drug Development
FEBRUARY 29, 2024
We had a client moving from an On-Prem v11 Optimizely instance to DXP v12 and we had a lot of blobs (over 40 GB) needing uploading to DXP as a part of the conversion. This was my first experience doing both a version and environment upgrade and I leaned heavily on Optimizely support to help me get it right. Along the way, I wrote down each step so that I could reference it for any future projects that were doing the same.
Drugs.com
FEBRUARY 29, 2024
THURSDAY, Feb. 29, 2024 -- Deaths where alcohol played a key role climbed sharply in recent years, hitting women even harder than men, new government data shows. Between 2016 and 2021 (the latest numbers available), "the average number of U.S.
Science Daily: Pharmacology News
FEBRUARY 29, 2024
Researchers show how biohybrid robots based on jellyfish could be used to gather climate science data from deep in the Earth's oceans.
Drugs.com
FEBRUARY 29, 2024
THURSDAY, Feb. 29, 2024 -- New research finds the 2022 mpox outbreak among gay and bisexual men began to slow down after just a few months -- even though just 8% of high-risk people had received the mpox vaccine. That suggests that it was changes.
Science Daily: Pharmacology News
FEBRUARY 29, 2024
An international team of astronomers obtained observational evidence for the creation of rare heavy elements in the aftermath of a cataclysmic explosion triggered by the merger of two neutron stars.
Drugs.com
FEBRUARY 29, 2024
THURSDAY, Feb. 29, 2024 -- Middle-aged folks who have difficulties navigating their way through space could be at higher risk of developing Alzheimer's disease years later, a new study finds.“Very early symptoms of dementia can be subtle and.
SCIENMAG: Medicine & Health
FEBRUARY 29, 2024
Researchers using a novel method of measuring long-term wildfire smoke exposure have found that Indigenous communities in California are exposed to disproportionate amounts of dangerous particulate matter — sometimes far beyond what has been previously known.
Drugs.com
FEBRUARY 29, 2024
THURSDAY, Feb. 29, 2024 -- The eyes may have it when it comes to the early diagnosis of autism in children, a new study finds.Researchers at the University of California, San Francisco (UCSF), have pinpointed a gene that affects how kids' eyes.
Fierce BioTech
FEBRUARY 29, 2024
After a few years characterised by uncertainty, the narrative across the biotech industry is changing.
Drugs.com
FEBRUARY 29, 2024
THURSDAY, Feb. 29, 2024 -- Teens have a higher risk of self-injury -- deliberately cutting or burning themselves -- if they have a fraught relationship with a struggling parent, a new study shows.Teenagers were nearly five times more likely to.
NIOSH Science Blog: Drugs
FEBRUARY 29, 2024
This World Hearing Day, March 3, 2024, the World Health Organization is promoting awareness of hearing loss to reduce societal misperceptions and stigma and is encouraging you to do the same. Over 80% of ear and hearing care needs are not met worldwide.[1] Hearing care has an annual cost of nearly $1 trillion (US) globally.[2] Changing mindsets on ear and hearing care is the first step to combatting this largely preventable global health issue.
Science Daily: Pharmacology News
FEBRUARY 29, 2024
Researchers have found water vapor in the disc around a young star exactly where planets may be forming. Water is a key ingredient for life on Earth, and is also thought to play a significant role in planet formation. Yet, until now, we had never been able to map how water is distributed in a stable, cool disc -- the type of disc that offers the most favorable conditions for planets to form around stars.
SCIENMAG: Medicine & Health
FEBRUARY 29, 2024
EAST LANSING, Mich. — Effective population level vaccination campaigns are fundamental to public health. Countercampaigns, which are as old as the first vaccines, can disrupt uptake and threaten public health globally. Credit: Courtesy: Young Anna Argyris EAST LANSING, Mich. — Effective population level vaccination campaigns are fundamental to public health.
Perficient: Drug Development
FEBRUARY 29, 2024
The goal of Databricks Unity Catalog is to provide centralized security and management to data and AI assets across the data lakehouse. Unity Catalog provides fine-grained access control for all the securable objects in the lakehouse; databases, tables, files and even models. Gone are the limitations of the Hive metadata store. The Unity Catalog metastore manages all data and AI assets across different workspaces and storage locations.
SCIENMAG: Medicine & Health
FEBRUARY 29, 2024
Metal nanomaterials have become an indispensable part of industrial and medical fields due to their unique and versatile properties. Their size, which imparts them with the desired physiochemical properties, is also the reason for environmental and health concerns.
BioPharma Drive: Drug Pricing
FEBRUARY 29, 2024
The unusual deal will see one of the investment firm’s startups work with Gilead to expand the cancer drug’s label, with Abingworth receiving payment if successful.
SCIENMAG: Medicine & Health
FEBRUARY 29, 2024
BATON ROUGE – The increased popularity of telehealth and telemedicine in recent years has provided a new level of accessibility for patients to visit doctors and learn more about their health. Certain remote measurements, however, have long been speculated to be less accurate and less trustworthy than when gathered at in-person appointments.
Science Daily: Pharmacology News
FEBRUARY 29, 2024
Using archival data from the Gemini North telescope, a team of astronomers has measured the heaviest pair of supermassive black holes ever found. The merging of two supermassive black holes is a phenomenon that has long been predicted, though never observed. This massive pair gives clues as to why such an event seems so unlikely in the Universe.
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