Tue.Feb 27, 2024

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Viking data suggest obesity drug could rival Zepbound, Wegovy

BioPharma Drive: Drug Pricing

The biotech’s drug led to significant weight loss in a Phase 2 trial, causing shares to double as analysts compared results to the marks set by drugs from Eli Lilly and Novo Nordisk.

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Do You Have An Enterprise Data Strategy?

Perficient: Drug Development

This time of year, I like to talk about updating the data strategy for the new year to include new business goals and new technology and in doing so I sometimes forget that there are still many companies that do not have a data strategy to update. What is a Data Strategy and why do I need one? Most organizations have multiple data management initiatives underway including master data management, data governance, data migration, data modernization, OLTP operational data cleanup, data ingestion, a

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New study links placental oxygen levels to fetal brain development

Science Daily: Pharmacology News

A new study shows oxygenation levels in the placenta, formed during the last three months of fetal development, are an important predictor of cortical growth (development of the outermost layer of the brain or cerebral cortex) and is likely a predictor of childhood cognition and behavior.

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Eye Ointments Sold at Walmart, CVS Recalled Due to Infection Risk

Drugs.com

TUESDAY, Feb. 27, 2024 -- Eye ointment products made in India and sold in the United States at Walmart, CVS and other retailers are being recalled due to a danger of infection.Brassica Pharma Pvt. Ltd., of Maharastra, India, said it is recalling.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Live from SCOPE 2024: Talk of the Towne featuring Rare Patient Voice

Antidote

We’re here with Antidote’s tenth installment of Talk of the Towne, and it’s a very special one! We recently attended SCOPE 2024, where we met up with our partners at Rare Patient Voice and recorded our first Talk of the Towne episode live and in person.

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What Is Chronic Sinusitis, and How Is it Treated?

Drugs.com

TUESDAY, Feb. 27, 2024 -- Stuffy, sneezing, miserable: folks plagued by chronic sinusitis know the feeling all too well.Experts at University of Cincinnati Health say it's also an all-too-common affliction, affecting an estimated 14.6% of.

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More Trending

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Firsthand Experience of Climate Change Disasters Is Stressing Teens

Drugs.com

TUESDAY, Feb. 27, 2024 -- Weather disasters driven by climate change are stressing out U.S. teenagers, a new study warns.Teens with the most firsthand experience of events like hurricanes, floods, tornadoes, droughts and wildfires were more likely.

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Pitt study shows bariatric surgery is more effective than medical and lifestyle interventions for diabetes control and remission

SCIENMAG: Medicine & Health

PITTSBURGH, Feb. 27, 2024 – Bariatric surgery is more effective than medical and lifestyle modifications for achieving long-term Type 2 diabetes control and remission, according to new research led by a University of Pittsburgh School of Medicine surgeon-scientist and published today in JAMA. Credit: UPMC PITTSBURGH, Feb.

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Cyberattack Stalls Prescription Dispensing at UnitedHealth

Drugs.com

TUESDAY, Feb. 2, 2024 -- For nearly a week, prescription drug orders have been disrupted at thousands of pharmacies as the largest health insurer in the United States tries to fully restore services following a cyberattack. The security breach was.

Pharmacy 105
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New study links placental oxygen levels to fetal brain development

SCIENMAG: Medicine & Health

A new study shows oxygenation levels in the placenta, formed during the last three months of fetal development, are an important predictor of cortical growth (development of the outermost layer of the brain or cerebral cortex) and is likely a predictor of childhood cognition and behaviour.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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You're Aware of Relaxing Words While Asleep, and They Calm the Heart

Drugs.com

TUESDAY, Feb. 27, 2024 -- The mind is alert to relaxing words spoken by others when you're asleep, so much so that your heart beat slows down, new research shows.Hearing words like "relax" and "easy" spoken while asleep appeared to help put study.

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Study details five cutting-edge advances in biomedical engineering and their applications in medicine

SCIENMAG: Medicine & Health

Bridging precision engineering and precision medicine to create personalized physiology avatars. Pursuing on-demand tissue and organ engineering for human health. Revolutionizing neuroscience by using AI to engineer advanced brain interface systems. Engineering the immune system for health and wellness. Designing and engineering genomes for organism repurposing and genomic perturbations.

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Lab Study Questions Safety of Tattoo Ink Ingredients

Drugs.com

TUESDAY, Feb. 27, 2024 -- Tattoos are a trendy way to decorate your body, but a new study reveals that the inks used in the process often contain unlisted substances that could cause health problems. An analysis of tattoo inks from nine.

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Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

SCIENMAG: Medicine & Health

Cells actively rely on maintaining an appropriate acid-base balance to support optimal function. Under normal physiological settings, the pH inside cells remains within a controlled range. However, disruptions in this equilibrium have been linked to a wide range of health conditions, both minor and catastrophic.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Which Families Are Less Likely to Get Teens the HPV Vaccine?

Drugs.com

TUESDAY, Feb. 27, 2024 -- Well-to-do American families are more likely than poorer families to increase their children’s risk of cervical cancer by skipping the human papillomavirus (HPV) vaccine, a new study has found.Nearly two-thirds of.

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How to Deposit Your Plasmids with Addgene

addgene Blog

At Addgene, it is our mission to make it easy for you to share plasmids. To achieve this goal, we will archive any plasmids you've deposited with us and distribute them to scientists worldwide. What's more, depositing is free! We've written this post as a step-by-step guide to the online deposit process.

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Drug-resistant tuberculosis responds rapidly to bedaquiline-based second-line therapy

SCIENMAG: Medicine & Health

Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens, according to researchers at Weill Cornell Medicine in New York and GHESKIO Centers in Haiti.

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Fat Around Men's Pancreas Might Raise Odds for Alzheimer's

Drugs.com

TUESDAY, Feb. 27, 2024 -- Excess fat around your pancreas could bode ill for the health of your aging brain, new research shows.But maybe only if you're male: The relationship wasn't observed among women, noted the team from Rutgers University in.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Determine stroke risk at an early stage using tear fluid, mitochondria and AI-based data

SCIENMAG: Medicine & Health

Every year, over 100 million people worldwide suffer a stroke. Ischemic strokes (cerebral infarction) are the most common, but they can also occur “silently” and therefore often go undetected. This can result in serious illnesses such as dementia, depression or even suicide. In order to determine the risk of stroke at an early stage, Prof.

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1 in 5 People Who Attempt Suicide Have No Prior Mental Illness

Drugs.com

TUESDAY, Feb. 27, 2024 -- One out of every five adults who attempt suicide never met the criteria for a mental illness by the time the attempt happened, new research shows.“This finding challenges clinical notions of who is at risk for suicidal.

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Janux shares triple on early cancer immunotherapy data

BioPharma Drive: Drug Pricing

Analysts viewed results for one of Janux’s drug, a T cell engager aimed at metastatic prostate cancer, as potentially best-in-class in a field that’s crowded with competitors.

Drugs 115
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Patient enrollment complete for clinical trial of 4B Technologies’ AI-discovered ALS drug supported by Insilico Medicine

SCIENMAG: Medicine & Health

Amyotrophic Lateral Sclerosis (ALS) is a fatal type of motor neuron disease characterized by progressive degeneration of nerve cells in the spinal cord and brain, resulting in muscle weakness and paralysis that can include the inability to walk and speak, or even swallow and breathe.

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Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections

Covalent Modifiers

Jeyun Jo, Tulsi Upadhyay, Emily C. Woods, Ki Wan Park, Nichole J. Pedowitz, Joanna Jaworek-Korjakowska, Sijie Wang, Tulio A. Valdez, Matthias Fellner, and Matthew Bogyo Journal of the American Chemical Society 2024 DOI: 10.1021/jacs.3c13974 Staphylococcus aureus (S. aureus) is a major human pathogen that is responsible for a wide range of systemic infections.

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Bariatric surgery provides long-term blood glucose control, type 2 diabetes remission

SCIENMAG: Medicine & Health

BATON ROUGE – People with type 2 diabetes who underwent bariatric surgery achieved much better long-term blood glucose control compared to people who received medical management plus lifestyle interventions, according to a new study published in JAMA, or Journal of the American Medical Association, and funded by the National institute of Diabetes, Digestive and Kidney […]

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Changing Mindsets on Hearing Disorders Associated with Work Hazards

NIOSH Science Blog: Drugs

The National Institute for Occupational Safety and Health’s (NIOSH) Hearing Loss Prevention Program has been an official member of the World Hearing Forum (WHF) since it was launched in 2019. The Forum was assembled by the Office of Ear and Hearing Care of the World Health Organization to promote ear and hearing care worldwide. NIOSH’s membership to the forum builds upon the Hearing Loss Prevention Program’s long-standing contributions to the prevention of work-related hearing loss.

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Nano-sized particles emitted from gas stoves

SCIENMAG: Medicine & Health

A study quantifies the emission of extremely tiny particles by gas stoves and finds that the particles could harm human health. Airborne nanoparticles between 1–3 nm, referred to as nanocluster aerosol or NCA, are known to be bioactive and toxic, but measuring such minute particles has been a challenge. Brandon E.

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Blocked Transmission

Codon

Tom Ough writes about how UVC light, metals, and surface coatings can help fend off pathogens for Issue 01. Read it on our website here. It was March 2003, and an unfortunate 33-year-old, known only as patient YY, was suffering from intense diarrhea. The man was in Hong Kong for kidney treatment. While in the city, he visited his brother in Block E of Amoy Gardens, a vast housing estate that looks rather like a set of vertical shortbread cookies.

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Drug Channels News Roundup, February 2024: Pharmacy Shakeout Update, High Drug Prices, 340B Realities, MDs vs. Pharmacists, and Foo Fighters

Drug Channels

February is longer than usual this year, which means that you’ll have extra time to leap into our monthly curated selection of noteworthy news. In this issue: An update on the retail pharmacy shakeout Arguing for high drug prices A leading researcher provides a 340B reality check Physicians don’t want pharmacists getting uppity Plus, Dave Grohl fights for your right to…have healthcare price transparency?

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Which pharmaceutical companies have the most drug patents in Brazil?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Brazil. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is… The post Which pharmaceutical companies have the most drug patents in Brazil? appeared first on DrugPatentWatch - Make Better Decisions.

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Surely You Must be Kidding, PTO?!? “No, and Don’t Call Me Shirley!” – The Seemingly Slapstick (But Yet Unfunny) World of Recent Patent Term Extension Decisions (PART 1)

FDA Law Blog: Biosimilars

By Kurt R. Karst — It’s been a while since we last blogged on Patent Term Extension (“PTE”) issues of interest. And with 2024 (September 24th) being the 40th anniversary of the enactment of the 1984 Hatch-Waxman Amendments—the statute that amended Title 35 of the United States Code to create PTEs for certain FDA-regulated products—and a recent spate of PTE-related items posted on regulations.gov, we thought we would peruse some decisions to see what’s up at the Patent and Trademark Office (“PTO

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New patent for Deciphera Pharms drug QINLOCK

Drug Patent Watch

Annual Drug Patent Expirations for QINLOCK Qinlock is a drug marketed by Deciphera Pharms and is included in one NDA. It is available from one supplier. There are twenty-two patents… The post New patent for Deciphera Pharms drug QINLOCK appeared first on DrugPatentWatch - Make Better Decisions.

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Minerva schizophrenia drug rejected by FDA

BioPharma Drive: Drug Pricing

The agency’s complete response letter knocks back Minerva’s attempt to secure approval of the drug over agency reviewers’ objections.

FDA 64
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More than Just Words: Prioritizing Patient-Centered Drug Development

LifeSciVC

By Ivana Magovčević-Liebisch, CEO of Vigil Neuroscience, as part of the From The Trenches feature of LifeSciVC Patients and their care partners are at the center of our work in the life sciences industry – but at what point during the drug development process should companies start to engage these key stakeholders? At Vigil, our answer was simple: from the beginning.