Mon.Dec 02, 2024

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Hidden fat predicts Alzheimer's 20 years ahead of symptoms

Science Daily: Pharmacology News

Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a new study. The researchers emphasized that lifestyle modifications targeted at reducing this fat could influence the development of Alzheimer's disease.

Disease 325
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Cervical Cancer Deaths Fell Dramatically After Advent of HPV Vaccine

Drugs.com

MONDAY, Dec. 2, 2024 -- A new study provides good evidence that the human papillomavirus (HPV) vaccine may be achieving its goal of slashing rates of cervical cancer.“We observed a … 62% drop in cervical cancer deaths over the last decade, likely du.

Vaccine 290
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How artificial intelligence could automate genomics research

Science Daily: Pharmacology News

New research suggests that large language models like GPT-4 could streamline the process of gene set enrichment, an approach what genes do and how they interact. Results bring science one step closer to automating one of the most widely used methods in genomics research.

Research 303
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Diabetes advocacy group discourages use of compounded GLP-1 drugs

BioPharma Drive: Drug Pricing

The ADA recommended doctors avoid prescribing unapproved, off-brand versions of drugs like Wegovy, wading into a dispute that has gripped the FDA and compounding pharmacies over the past few months.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Temporary tattoo printed directly on the scalp offers easy, hair-friendly solution for measuring brainwaves

Science Daily: Pharmacology News

Scientists have invented a liquid ink that doctors can print onto a patient's scalp to measure brain activity. The technology offers a promising alternative to the cumbersome process currently used for monitoring brainwaves and diagnosing neurological conditions. It also has the potential to enhance non-invasive brain-computer interface applications.

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Researchers deal a blow to theory that Venus once had liquid water on its surface

Science Daily: Pharmacology News

A team of astronomers has found that Venus has never been habitable, despite decades of speculation that our closest planetary neighbor was once much more like Earth than it is today.

Research 278
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Novocure device succeeds in pancreatic cancer study; FDA sets Cytokinetics decision date

BioPharma Drive: Drug Pricing

Using tumor-treating fields alongside chemotherapy improved patient survival, Novocure said. Elsewhere, Cytokinetics got a key PDUFA date and Fate Therapeutics swapped CEOs.

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Smallest walking robot makes microscale measurements

Science Daily: Pharmacology News

Researchers have created the smallest walking robot yet. Its mission: to be tiny enough to interact with waves of visible light and still move independently, so that it can maneuver to specific locations -- in a tissue sample, for instance -- to take images and measure forces at the scale of some of the body's smallest structures.

Research 278
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Salmonella Outbreak Triggers Recall of Cucumbers in 26 States

Drugs.com

MONDAY, Dec. 2, 2024 -- Sixty-eight people have been sickened and 18 have been hospitalized in a salmonella outbreak linked to whole cucumbers sold in 26 states and parts of Canada."Epidemiologic and traceback information shows that cucumbers grown.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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New 3D printing approach means better biomedical, energy, robotics devices

Science Daily: Pharmacology News

A researcher has helped create a new 3D printing approach for shape-changing materials that are likened to muscles, opening the door for improved applications in robotics as well as biomedical and energy devices.

Research 274
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Workers Who Make Kitchen Countertops Face Big Lung Hazards

Drugs.com

MONDAY, Dec. 2, 2024 -- The workers who cut and finished your sleek stone countertop may be paying a price in poor lung health, new research shows.Breathing in dust created by the manufacture of countertops can cause the lung disease silicosis.

Disease 246
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Insect fossil find 'extremely rare'

Science Daily: Pharmacology News

Newly discovered insect fossils are so small they can barely be seen by the human eye but have been preserved in an 'extraordinary' way.

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Smoker or Former Smoker? Here Are 4 Key Things You Need to Know

Drugs.com

MONDAY, Dec.2, 2024 — Doctors have potent new weapons against the deadliest cancer in America and they want to make sure they're on the radar of current and former smokers."Lung cancer screening is the most powerful tool we have to lower cancer [.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Are You Using Next-Gen Sequencing to inform AAV product and process quality? Here are 4 reasons you should

BioPharma Drive: Drug Pricing

Next-generation sequencing allows for critical insights into gene therapy products, which can help streamline and accelerate everything from process development and production to regulatory approval.

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Antibiotics or Surgery: What's Best for Child Appendicitis?

Drugs.com

MONDAY, Dec. 2, 2024 -- For decades, surgery to remove an inflamed appendix has been a rite of childhood for many.But a new study says treating appendicitis with antibiotics, rather than surgery, is the best way to address most cases.Using.

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Researchers demonstrate self-assembling electronics

Science Daily: Pharmacology News

Researchers have demonstrated a new technique for self-assembling electronic devices. The proof-of-concept work was used to create diodes and transistors, and paves the way for self-assembling more complex electronic devices without relying on existing computer chip manufacturing techniques.

Research 229
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Over 100,000 U.S. Youth Battle Inflammatory Bowel Disease

Drugs.com

MONDAY, Dec.2, 2024 -- Cases of inflammatory bowel disease (IBD) are rising at an alarming rate among young Americans, a new study reveals."Prevalence rates [are] among the highest reported worldwide," said researcher Dr. Michael Kappelman, a.

Disease 242
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Applied’s rare disease drug rejected by FDA

BioPharma Drive: Drug Pricing

Executives at Applied Therapeutics told analysts they were surprised by the agency’s refusal to approve the company’s treatment for classic galactosemia.

Disease 130
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Switch From Animal to Plant Proteins Greatly Boosts Heart Health

Drugs.com

MONDAY, Dec. 2, 2024 -- Moving away from meat to plants as a main source of protein will do wonders for your heart, new research finds.The 30-year study found that folks with the highest ratio of plant-based protein to animal-based protein cut.

Research 240
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A Guide to Randomisation in Clinical Trials

Quanticate

Double-blind randomised controlled trials (RCTs) are the gold standard for evaluating clinical interventions in the biomedical field. A defining feature of RCTs is that of randomisation, the statistical process whereby participants are assigned to different treatment groups according to a predefined random mechanism. Whether the mechanism is simple or complex, the rationale remains the same – to uphold the scientific rigor essential for generating unbiased, credible, and generalisable clinical e

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CTE Plus Family History of Mental Illness Raises Odds for Aggression

Drugs.com

MONDAY, Dec. 2, 2024 -- Concussion-related brain damage can combine with a family history of mental illness to make some athletes and military personnel prone to aggression and violence in middle age, a new study says. People with chronic traumatic.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Explore Our Latest Scientific Posters From the ACT Meeting

Alta Sciences

Explore Our Latest Scientific Posters From the ACT Meeting blussier Mon, 12/02/2024 - 19:22 HTML Groundbreaking Research Data You Can Use Catch up on the latest insights! Our experts’ posters from the 45th Annual ACT Meeting are now available online: Leveraging Nonclinical Safety Evaluation Findings to Expedite Next-Generation Glucagon-Like Peptide-1 Receptor Agonists Development for Metabolic Disorders and Beyond presented by Dr.

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Newer Epilepsy Meds Safe During Pregnancy, Won't Affect Kids' Neurodevelopment

Drugs.com

MONDAY, Dec. 2, 2024 -- For decades, it's been known that certain older medications women use to control epilepsy seizures can pose risks to a fetus. However, data now suggests that no such risk exists for newer-generation anti-seizure meds.“We n.

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Evidence of primordial black holes may be hiding in planets, or even everyday objects here on Earth

Science Daily: Pharmacology News

A theoretical study suggests that small black holes born in the early universe may have left behind hollow planetoids and microscopic tunnels, and that we should start looking within rocks and old buildings for them. The research proposes thinking both big and small to confirm the existence of primordial black holes, suggesting that their signatures could range from very large -- hollow planetoids in space -- to minute -- microscopic tunnels in everyday materials found on Earth, like rocks, meta

Research 303
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When's Best Time for Your COVID Booster? That May Depend on You

Drugs.com

MONDAY, Dec. 2, 2024 -- Folks might want to try timing their COVID-19 booster vaccine to coincide with a period of increased transmission in their area, a new study suggests.Doing so can improve protection against COVID infection as much as.

Vaccine 130
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New Business Models for Pharmaceutical Marketing: Transforming Data into Market Domination

Drug Patent Watch

The traditional marketing models that once dominated the pharmaceutical industry are rapidly becoming obsolete, paving the way for innovative approaches that leverage technology, data, and patient-centricity. This comprehensive guide explores the new business models reshaping pharmaceutical marketing, offering insights into how companies can transform their strategies to achieve market domination.