Mon.Dec 02, 2024

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Novartis wagers billions of dollars on PTC Huntington’s drug

BioPharma Drive: Drug Pricing

At the center of a new licensing deal is an experimental medicine, PTC518, which is currently being tested in a roughly 250-person study that should produce results next year.

Licensing 115
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Antibiotics or Surgery: What's Best for Child Appendicitis?

Drugs.com

MONDAY, Dec. 2, 2024 -- For decades, surgery to remove an inflamed appendix has been a rite of childhood for many.But a new study says treating appendicitis with antibiotics, rather than surgery, is the best way to address most cases.Using.

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Researchers demonstrate self-assembling electronics

Science Daily: Pharmacology News

Researchers have demonstrated a new technique for self-assembling electronic devices. The proof-of-concept work was used to create diodes and transistors, and paves the way for self-assembling more complex electronic devices without relying on existing computer chip manufacturing techniques.

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Are You Using Next-Gen Sequencing to inform AAV product and process quality? Here are 4 reasons you should

BioPharma Drive: Drug Pricing

Next-generation sequencing allows for critical insights into gene therapy products, which can help streamline and accelerate everything from process development and production to regulatory approval.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Smoker or Former Smoker? Here Are 4 Key Things You Need to Know

Drugs.com

MONDAY, Dec.2, 2024 — Doctors have potent new weapons against the deadliest cancer in America and they want to make sure they're on the radar of current and former smokers."Lung cancer screening is the most powerful tool we have to lower cancer [.

Doctors 80
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How artificial intelligence could automate genomics research

Science Daily: Pharmacology News

New research suggests that large language models like GPT-4 could streamline the process of gene set enrichment, an approach what genes do and how they interact. Results bring science one step closer to automating one of the most widely used methods in genomics research.

More Trending

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Temporary tattoo printed directly on the scalp offers easy, hair-friendly solution for measuring brainwaves

Science Daily: Pharmacology News

Scientists have invented a liquid ink that doctors can print onto a patient's scalp to measure brain activity. The technology offers a promising alternative to the cumbersome process currently used for monitoring brainwaves and diagnosing neurological conditions. It also has the potential to enhance non-invasive brain-computer interface applications.

Doctors 82
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Workers Who Make Kitchen Countertops Face Big Lung Hazards

Drugs.com

MONDAY, Dec. 2, 2024 -- The workers who cut and finished your sleek stone countertop may be paying a price in poor lung health, new research shows.Breathing in dust created by the manufacture of countertops can cause the lung disease silicosis.

Disease 69
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Evidence of primordial black holes may be hiding in planets, or even everyday objects here on Earth

Science Daily: Pharmacology News

A theoretical study suggests that small black holes born in the early universe may have left behind hollow planetoids and microscopic tunnels, and that we should start looking within rocks and old buildings for them. The research proposes thinking both big and small to confirm the existence of primordial black holes, suggesting that their signatures could range from very large -- hollow planetoids in space -- to minute -- microscopic tunnels in everyday materials found on Earth, like rocks, meta

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New Business Models for Pharmaceutical Marketing: Transforming Data into Market Domination

Drug Patent Watch

The traditional marketing models that once dominated the pharmaceutical industry are rapidly becoming obsolete, paving the way for innovative approaches that leverage technology, data, and patient-centricity. This comprehensive guide explores the new business models reshaping pharmaceutical marketing, offering insights into how companies can transform their strategies to achieve market domination.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Hidden fat predicts Alzheimer's 20 years ahead of symptoms

Science Daily: Pharmacology News

Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a new study. The researchers emphasized that lifestyle modifications targeted at reducing this fat could influence the development of Alzheimer's disease.

Disease 73
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December Fellow's Spotlight on Dr. Christian Cazares

keypoint

December's Fellows Spotlight goes to Keystone Symposia Fellow Dr. Christian Cazares. Dr. Cazares is a postdoctoral researcher in the Cognitive Science Department at UC San Diego, where he studies neurodevelopmental disorders. He is also a strong advocate for mentorship and DEI, having launched a mentorship program for undergraduates in his spare time.

Science 65
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Researchers deal a blow to theory that Venus once had liquid water on its surface

Science Daily: Pharmacology News

A team of astronomers has found that Venus has never been habitable, despite decades of speculation that our closest planetary neighbor was once much more like Earth than it is today.

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Diabetes advocacy group discourages use of compounded GLP-1 drugs

BioPharma Drive: Drug Pricing

The ADA recommended doctors avoid prescribing unapproved, off-brand versions of drugs like Wegovy, wading into a dispute that has gripped the FDA and compounding pharmacies over the past few months.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Smallest walking robot makes microscale measurements

Science Daily: Pharmacology News

Researchers have created the smallest walking robot yet. Its mission: to be tiny enough to interact with waves of visible light and still move independently, so that it can maneuver to specific locations -- in a tissue sample, for instance -- to take images and measure forces at the scale of some of the body's smallest structures.

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Over 100,000 U.S. Youth Battle Inflammatory Bowel Disease

Drugs.com

MONDAY, Dec.2, 2024 -- Cases of inflammatory bowel disease (IBD) are rising at an alarming rate among young Americans, a new study reveals."Prevalence rates [are] among the highest reported worldwide," said researcher Dr. Michael Kappelman, a.

Disease 59
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New 3D printing approach means better biomedical, energy, robotics devices

Science Daily: Pharmacology News

A researcher has helped create a new 3D printing approach for shape-changing materials that are likened to muscles, opening the door for improved applications in robotics as well as biomedical and energy devices.

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Switch From Animal to Plant Proteins Greatly Boosts Heart Health

Drugs.com

MONDAY, Dec. 2, 2024 -- Moving away from meat to plants as a main source of protein will do wonders for your heart, new research finds.The 30-year study found that folks with the highest ratio of plant-based protein to animal-based protein cut.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Novocure device succeeds in pancreatic cancer study; FDA sets Cytokinetics decision date

BioPharma Drive: Drug Pricing

Using tumor-treating fields alongside chemotherapy improved patient survival, Novocure said. Elsewhere, Cytokinetics got a key PDUFA date and Fate Therapeutics swapped CEOs.

FDA 59
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Insect fossil find 'extremely rare'

Science Daily: Pharmacology News

Newly discovered insect fossils are so small they can barely be seen by the human eye but have been preserved in an 'extraordinary' way.

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How to Create Joined Reports in Salesforce: A Comprehensive Guide

Perficient: Drug Development

Hello Trailblazers! Salesforce offers a range of reporting formats to help businesses understand and analyze their data. Among these, Joined Reports stand out as one of the most powerful reporting tools. They allow users to combine and compare data across multiple report types and objects within a single report. In this blog, we’ll explore what joined reports are and when to use them, and provide a step-by-step guide to creating and customizing a joined report in Salesforce.

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How Many Hours are Really in a Day?

FDA Law Blog: Biosimilars

By Adrienne R. Lenz, Principal Medical Device Regulation Expert & Kristy Katzenmeyer-Pleuss, Regulatory and Biological Safety Consultant* — We recently blogged on FDA’s draft guidance, Chemical Analysis for Biocompatibility Assessment of Medical Devices , which describes chemical characterization methods that may be used to demonstrate biocompatibility of a medical device as an alternative to conducting certain biological testing.

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Effortless Development of LWCs in Local Dev

Perficient: Drug Development

The Salesforce Winter ’25 Release unveils an exciting feature for developers: Local Dev (Beta). This cutting-edge tool allows developers to create Lightning Web Components (LWCs) with a real-time preview of their Lightning app or Experience Cloud site using the Lightning Web Runtime. With Local Dev, code changes are instantly reflected in the browser, streamlining the development process and boosting productivity.

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Sloane’s 4th Dose

KIF1A

Hi KIF1A Families, Sloane received her forth ASO dose in October at 80mg. This dosing consisted of pre-dose bloodwork, research EEG, PT evaluation, and a cognitive evaluation. The biggest changes we have seen so far have been in her speech and cognitive awareness. She recently started counting to 10 on her own! We are noticing slightly lower tension in her legs and a stronger core.

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EF Core: Stored Procedure Multiple Result Sets

Perficient: Drug Development

Stored procedures are powerful tools for running complex database operations efficiently. EF Core execute stored procedure multiple result sets, a technique that can improve performance and simplify data retrieval. It’s important to handle the results properly when working with stored procedures that return multiple tables. Entity Framework Core allows you to execute stored procedures and process multiple result sets.

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Six Reasons to Work with a Patient Recruitment Vendor from Study Launch

Antidote

Launching a clinical trial is a complex and challenging process, with many moving parts to consider. From navigating regulatory requirements to recruiting the right patients, sponsors often face significant hurdles. One decision is selecting a vendor to support patient recruitment throughout the trial. While it might seem like a decision that can be made after the trial launches, there are compelling reasons why partnering with a dedicated patient recruitment vendor right from the beginning is a

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Perficient Included in IDC Market Glance: Enterprise Intelligence Services Report

Perficient: Drug Development

Intelligence is the new currency of business – the ability to transform raw data into actionable insights isn’t just a competitive advantage, it’s a strategic imperative. Organizations are rapidly discovering that enterprise intelligence is the key to unlocking unprecedented business value, driving decision-making, and creating transformative experiences.

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CTE Plus Family History of Mental Illness Raises Odds for Aggression

Drugs.com

MONDAY, Dec. 2, 2024 -- Concussion-related brain damage can combine with a family history of mental illness to make some athletes and military personnel prone to aggression and violence in middle age, a new study says. People with chronic traumatic.

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A Journey Through ProPharma's REMS Program Support

thought leadership

This fictional story illustrates how ProPharma can seamlessly support a REMS program to ensure patient safety, access to medication, and regulatory compliance. Through scenarios involving healthcare providers like Dr. Emily and patients like Sarah, we demonstrate how ProPharma's services—from inquiry support and adverse event management to training and education—empower providers and improve patient outcomes.

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Newer Epilepsy Meds Safe During Pregnancy, Won't Affect Kids' Neurodevelopment

Drugs.com

MONDAY, Dec. 2, 2024 -- For decades, it's been known that certain older medications women use to control epilepsy seizures can pose risks to a fetus. However, data now suggests that no such risk exists for newer-generation anti-seizure meds.“We n.

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Applied’s rare disease drug rejected by FDA

BioPharma Drive: Drug Pricing

Executives at Applied Therapeutics told analysts they were surprised by the agency’s refusal to approve the company’s treatment for classic galactosemia.

Disease 52
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When's Best Time for Your COVID Booster? That May Depend on You

Drugs.com

MONDAY, Dec. 2, 2024 -- Folks might want to try timing their COVID-19 booster vaccine to coincide with a period of increased transmission in their area, a new study suggests.Doing so can improve protection against COVID infection as much as.

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December Fellow's Spotlight on Dr. Christian Cazares

keypoint

December's Fellows Spotlight goes to Keystone Symposia Fellow Dr. Christian Cazares. Dr. Cazares is a postdoctoral researcher in the Cognitive Science Department at UC San Diego, where he studies neurodevelopmental disorders. He is also a strong advocate for mentorship and DEI, having launched a mentorship program for undergraduates in his spare time.

Science 40