Thu.Mar 20, 2025

article thumbnail

New DESI results strengthen hints that dark energy may evolve

Science Daily: Pharmacology News

The Dark Energy Spectroscopic Instrument used millions of galaxies and quasars to build the largest 3D map of our universe to date. Combining their data with other experiments shows signs that the impact of dark energy may be weakening over time -- and the standard model of how the universe works may need an update.

289
289
article thumbnail

Alnylam drug gets long-awaited FDA approval in deadly heart disease

BioPharma Drive: Drug Pricing

Amvuttra’s clearance in a rare form of cardiomyopathy could help Alnylam turn a regular profit — if it can wrest control of a competitive and fast-changing market.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Oxygen discovered in most distant known galaxy

Science Daily: Pharmacology News

Astronomers have detected oxygen in the most distant known galaxy, JADES-GS-z14-0. This record-breaking detection is making astronomers rethink how quickly galaxies formed in the early Universe.

265
265
article thumbnail

Ears Ringing? Diet Changes Might Reduce Risk Of Tinnitus

Drugs.com

THURSDAY, March 20, 2025 -- Lowering the volume on earbuds or wearing earplugs in noisy environments is known to reduce a persons risk of tinnitus. Now, new research suggests that eating more fruit and fiber or drinking more milk and coffee may a.

Research 245
article thumbnail

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

article thumbnail

Galapagos birds exhibit 'road rage' due to noise

Science Daily: Pharmacology News

A new study has discovered that birds in the Galapagos Islands are changing their behavior due to traffic noise, with those frequently exposed to vehicles showing heightened levels of aggression. During trials involving traffic noise, Galapagos yellow warblers (Setophaga petechia aureola) increased the duration of their songs, increased the minimum frequencies of their songs (to reduce overlap with the traffic noise), and birds living close to roads displayed increased physical aggression.

Trials 260

More Trending

article thumbnail

The cell's powerhouses: Molecular machines enable efficient energy production

Science Daily: Pharmacology News

Mitochondria are the powerhouses in our cells, producing the energy for all vital processes. Using cryo-electron tomography, researchers have now gained insight into the architecture of mitochondria at unprecedented resolution. They discovered that the proteins responsible for energy generation assemble into large 'supercomplexes', which play a crucial role in providing the cell's energy.

article thumbnail

ADHD Misinformation Rampant On TikTok

Drugs.com

THURSDAY, March 20, 2025 -- TikToks most popular videos on ADHD are as likely to misinform viewers as they are to provide helpful hints, a new study says.More than half the claims made in the 100 most-viewed TikTok videos about a.

232
232
article thumbnail

Novartis builds case for new SMA gene therapy

BioPharma Drive: Drug Pricing

To Novartis, fresh late-stage data support the idea that its intrathecal drug, which has the same active ingredient as Zolgensma, could be approved for a broad range of spinal muscular atrophy patients.

Therapies 195
article thumbnail

Another Raw Pet Food Recalled After Bird Flu Sickens Two Cats

Drugs.com

THURSDAY, March 20, 2025 -- A California pet food company has recalled raw chicken products after they were linked to bird flu infections in two cats and suspected in a third in New York City. Savage Pet, based in El Cajon, California, recalled one.

article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

New AI tool generates high-quality images faster than state-of-the-art approaches

Science Daily: Pharmacology News

Researchers developed a hybrid AI approach that can generate realistic images with the same or better quality than state-of-the-art diffusion models, but that runs about nine times faster and uses fewer computational resources. The tool uses an autoregressive model to quickly capture the big picture and then a small diffusion model to refine the details of the image.

Research 182
article thumbnail

New Clot-Busting Drug Quicker And As Effective In Treating Stroke

Drugs.com

THURSDAY, March 20, 2025 -- A newly approved clot- busting drug for stroke works as well as a decades-old medication still used by most U.S. hospitals, and can be delivered even more quickly, a new study says.Tenecteplase (TNKase) is the first new.

Hospitals 208
article thumbnail

Sanofi wagers $600M on a dual-targeting antibody drug for autoimmune disease

BioPharma Drive: Drug Pricing

The deal with startup Dren Bio hands Sanofi a so-called myeloid cell engager that would compete with an array of programs aiming to “reset” the immune systems of people with inflammatory conditions.

Disease 177
article thumbnail

Combination Therapy Recommended For Migraines

Drugs.com

THURSDAY, March 20, 2025 -- Doctors should prescribe triptans for migraine patients who arent receiving relief from over-the-counter (OTC) pain relievers, according to a new clinical guideline from the American College of Physicians.The r.

Therapies 195
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Insomniac fruit fly mutants show enhanced memory despite severe sleep loss

Science Daily: Pharmacology News

Fruit fly mutants that have severe sleep deficits perform better at olfactory learning and memory tasks, according to a new study. The paradox of enhanced memory despite sleep loss could be explained by protein kinase A (PKA) signaling in the mushroom body of the fly brain.

145
145
article thumbnail

Dance Soothes Agitation In Alzheimer's Patients

Drugs.com

THURSDAY, March 20, 2025 -- Dancing is known to lift the spirit, and a new study shows that Alzheimers disease patients respond to the rhythmic moves as well.Dance classes eased agitation in a small group of people with Alzheimers disease and oth.

Disease 162
article thumbnail

Gene Therapy Studies and Germline Integration Assessment in Nonhuman Primates

Alta Sciences

Gene Therapy Studies and Germline Integration Assessment in Nonhuman Primates lperez Thu, 03/20/2025 - 22:44 Publication Poster_Altasciences_SOT_2025Gene_Therapy_Studies_and_Germline_Integration_Assessment_in_NHPs.

article thumbnail

Tonsil Removal Helps Kids With Snoring/Sleep Apnea

Drugs.com

THURSDAY, March 20, 2025 -- Removing the tonsils and adenoids can improve the sleep of kids with mild breathing problems that disturb their slumber, a new clinical trial reports.Children with sleep problems needed to see a doctor 32% less often and.

article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Standardization and Harmonization of Altasciences Historical Control Database Development Using Certara SEND Explorer® for Integrated Toxicological Evaluation

Alta Sciences

Standardization and Harmonization of Altasciences Historical Control Database Development Using Certara SEND Explorer for Integrated Toxicological Evaluation lperez Thu, 03/20/2025 - 22:46 Publication Poster_Altasciences_SOT_2025Standardization_and_Harmonization_of_Altasciences_HCD.

article thumbnail

FDA Increases Testing For Heavy Metals In Baby Formula

Drugs.com

THURSDAY, March 20, 2025 -- The U.S. Food and Drug Administration (FDA) is stepping up testing for heavy metals in infant formula and reviewing key nutrients required in these products, federal health officials said. "The FDA will use all resources.

FDA 130
article thumbnail

Targeted Gene Therapy for CNS Disorders: Precision of Intra-Cerebroventricular (ICV) Delivery and Post-Administration Behavioral Assessments in Mice

Alta Sciences

Targeted Gene Therapy for CNS Disorders: Precision of Intra-Cerebroventricular (ICV) Delivery and Post-Administration Behavioral Assessments in Mice lperez Thu, 03/20/2025 - 22:48 Publication Poster_Altasciences_SOT_2025Targeted_Gene_Therapy_for_CNS_Disorders.

article thumbnail

From dinosaurs to birds: the origins of feather formation

Science Daily: Pharmacology News

Feathers, essential for thermoregulation, flight, and communication in birds, originate from simple appendages known as proto-feathers, which were present in certain dinosaurs.By studying embryonic development of the chicken, researchers from the University of Geneva (UNIGE) have uncovered a key role of a molecular signalling pathway (the Shh pathway) in their formation.

Research 292
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

A 13-Week Dermal Toxicity Study of VIM-004 Gel, a STAR Particles Based Formulation in Göttingen Minipigs®

Alta Sciences

A 13-Week Dermal Toxicity Study of VIM-004 Gel, a STAR Particles Based Formulation in Gttingen Minipigs lperez Thu, 03/20/2025 - 22:49 Publication Poster_Altasciences_SOT_2025A_13-Week_Dermal_Toxicity_Study_in_Gottingen_Minipigs.

article thumbnail

Why don't we remember being a baby? New study provides clues

Science Daily: Pharmacology News

Though we learn so much during our first years of life, we can't, as adults, remember specific events from that time. Researchers have long believed we don't hold onto these experiences because the part of the brain responsible for saving memories -- the hippocampus -- is still developing well into adolescence and just can't encode memories in our earliest years.

Research 278
article thumbnail

Potential Role of Hesperidin in Improving Experimental Pulmonary Arterial Hypertension in Rats via Modulation of the NF‐κB Pathway

Chemical Biology and Drug Design

The figure illustrates the therapeutic effects of hesperidin on monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH) in a rat model. Hesperidin improves PAH by reducing right ventricular systolic pressure, Fulton index, and mean pulmonary arterial pressure while increasing pulmonary artery velocity time integral and acceleration time. It also suppresses inflammation by inhibiting the NF-B pathway, leading to decreased expression of inflammatory cytokines and markers of vascular remo

Treatment 100
article thumbnail

Novel memristors to overcome AI's 'catastrophic forgetting'

Science Daily: Pharmacology News

Memristors consume extremely little power and behave similarly to brain cells. Researchers have now introduced novel memristive that offer significant advantages: they are more robust, function across a wider voltage range, and can operate in both analog and digital modes. Their unique properties could help address the problem of 'catastrophic forgetting,' where artificial neural networks abruptly forget previously learned information.

Research 171
article thumbnail

Measles Erases Immune Memory, Stifling Protection from Other Infections

PLOS: DNA Science

Measles virus has long occupied a top spot on a list of most dangerous pathogens, for in addition to spreading easily, it can temporarily cancel immunity against other infectious diseases. A powerful vaccine has vanquished measles since 1963, offering close-to-lifetime immunity. But the disease is returning, thanks to vaccine hesitancy and apparent lack of knowledge of basic biology.

Virus 67