Mon.Dec 23, 2024

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Twisted Edison: Bright, elliptically polarized incandescent light

Science Daily: Pharmacology News

Bright, twisted light can be produced with technology similar to an Edison light bulb, researchers have shown. The finding adds nuance to fundamental physics while offering a new avenue for robotic vision systems and other applications for light that traces out a helix in space.

Research 316
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FDA Approves First Generic of GLP-1 Receptor Agonist Victoza (liraglutide injection) to Lower Blood Sugar in Patients with Type 2 Diabetes

Drugs.com

December 23, 2024 -- Today, the U.S. Food and Drug Administration approved the first generic referencing Victoza (liraglutide injection) 18 milligram/3 milliliter, a glucagon-like peptide-1 (GLP-1) receptor agonist indicated to improve glycemic.

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Crossing the Uncanny Valley: Breakthrough in technology for lifelike facial expressions in androids

Science Daily: Pharmacology News

Even highly realistic androids can cause unease when their facial expressions lack emotional consistency. Traditionally, a 'patchwork method' has been used for facial movements, but it comes with practical limitations. A team developed a new technology using 'waveform movements' to create real-time, complex expressions without unnatural transitions.

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GLP-1 Zepbound Is Approved As First Drug For Sleep Apnea

Drugs.com

MONDAY, Dec. 23, 2024 -- The U.S. Food and Drug Administration (FDA) has approved the first prescription medication specifically for treating obstructive sleep apnea (OSA): the weight-loss drug Zepbound. In a news release published Dec. 20, the FDA.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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New research improves the safety and effectiveness of ADC cancer treatments

Drug Target Review

Antibody-drugconjugates (ADCs) represent a significant advancement in drug discovery, combining the precision of monoclonal antibodies with the cancer-killing power of cytotoxic drugs. While these therapies hold great promise for improving cancer treatment outcomes, their development presents significant challenges, especially in achieving the optimal balance between efficacy and safety.

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Synthesis and Activity Study of Gefitinib Derivatives Inducing Mitochondrial Apoptosis in Hela Cells

Chemical Biology and Drug Design

We have discovered a gefitinib derivative that can inhibit IDO1 enzyme activity in Hela cells, thereby inducing apoptosis in these cells. ABSTRACT Cervical cancer is the fourth most common cancer among women globally. Its development is closely linked to accelerated cell cycle progression and the inhibition of apoptosis in cervical cancer tissues. Gefitinib has demonstrated efficacy in inhibiting cervical cancer cells, and the 1,2,3-triazole structure is widely recognized for its role in inducin

Research 100
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Dancing Helps People With Parkinson’s In More Ways Than One

Drugs.com

MONDAY, Dec. 23, 2024 -- Dancing appears to lift the spirits of people with Parkinsons disease.Depression eased in Parkinsons patients who took months of dance classes, a new study published recently in the Journal of Medical Internet Research sho.

Research 246
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Pharmacy Considerations for Early Phase Trials

Fierce BioTech

Pharmacy Considerations for Early Phase Trials dwunderlin Mon, 12/23/2024 - 15:20 Wed, 02/12/2025 - 14:00 Resource Type Webinar Todd Janssen, RPh Donnie Keeney, PharmD Sheri Sander Duration 60 Minutes From sterile compounding to handling controlled substances, a crucial aspect of conducting successful early phase trials is the careful preparation of both investigational and non-investigational products to be used in a clinical trial setting.

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More of America's Pets Are Overdosing on Stray Coke, Meth

Drugs.com

MONDAY, Dec. 23, 2024 -- Hundreds of beloved pet dogs and cats were reported as being unintentionally poisoned by cocaine and methamphetamine left out in their owners' homes, new data from one U.S. pet poison control hotline shows.When a dog or cat.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Drug Patent Expirations for the Week of December 22, 2024

Drug Patent Watch

VICTRELIS (boceprevir) Merck sharp dohme Patent: RE43298 Expiration: Dec 22, 2024 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.

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Autism Tops List of Worldwide Youth Health Issues

Drugs.com

MONDAY, Dec. 23, 2024 -- Autism ranks among the top ten health problems for young people under 20.A new study published recently in The Lancet Psychiatry says that nearly 62 million people in 2021 had autism spectrum disorder.We estimated one in 1.

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Webinar-Nanomilling-Updated 2024

Alta Sciences

Webinar-Nanomilling-Updated 2024 tchichekian Mon, 12/23/2024 - 20:39 Image Webinar_CDMO Nanosuspension Formulations.

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The Most Therapeutic Kind of Me-Time

Drugs.com

MONDAY, Dec. 23, 2024 -- What type of me-time is more restorative to a person -- hiking by yourself deep in a forest, or reading a book while sipping a latte in a coffee shop?Surprisingly, youll do best with a cup of joe and a good book, alone wi.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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HPAPI Manufacturing Webinar_Updated 2024

Alta Sciences

HPAPI Manufacturing Webinar_Updated 2024 tchichekian Mon, 12/23/2024 - 20:18 Image slide1.

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Feeling Appreciated by Partner is Critical for Caregiver's Mental Health

Drugs.com

MONDAY, Dec. 23, 2024 -- Everyone needs to feel appreciated -- but especially someone whos caring for a spouse with dementia.A study published recently in the journal Comprehensive Psychoneuroendocrinology shows that the mental health of c.

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HPAPI Manufacturing Webinar_Updated 2024

Alta Sciences

HPAPI Manufacturing Webinar_Updated 2024 tchichekian Mon, 12/23/2024 - 20:18 Image High Potency Manufacturing Solutions.

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Coffee Can Boost the Brains of People with Certain Heart Conditions

Drugs.com

MONDAY, Dec. 23, 2024 -- Coffee provides a quick morning boost, but it might also protect the brain health of people with a common heart rhythm disorder.A study published recently in the Journal of the American Heart Association shows patients with.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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HPAPI Manufacturing Webinar_Updated 2024

Alta Sciences

HPAPI Manufacturing Webinar_Updated 2024 tchichekian Mon, 12/23/2024 - 20:18 Image High Potency Manufacturing Solutions_1.

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Don't Forget About Holiday Poisoning Pitfalls

Drugs.com

Dec. 23, 2024 -- Poison experts see it every winter holiday season: Parents rush kids to the emergency room or call hotlines, panicking that their child has ingested something dangerous.Between holiday breaks, visiting relatives' homes, attending.

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HPAPI Manufacturing Webinar_Updated 2024

Alta Sciences

HPAPI Manufacturing Webinar_Updated 2024 tchichekian Mon, 12/23/2024 - 20:18 Image High Potency Manufacturing Solutions_2.

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Flu Cases Start to Surge as Americans Prepare for Holiday Gatherings

Drugs.com

MONDAY, Dec. 23, 2024 -- Predictably, flu season is in full swing, with cases surging across the United States, the Centers for Disease Control and Prevention (CDC) confirmed Friday in a report.Thirteen states, including Tennessee and Louisiana.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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HPAPI Manufacturing Webinar_Updated 2024

Alta Sciences

HPAPI Manufacturing Webinar_Updated 2024 tchichekian Mon, 12/23/2024 - 20:18 Image High Potency Manufacturing Solutions_3.

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GLP-1 Receptor Agonist Zepbound Approved as First Drug for Obstructive Sleep Apnea in Individuals with Obesity

Drugs.com

MONDAY, Dec. 23, 2024 -- The U.S. Food and Drug Administration (FDA) has approved the first prescription medication specifically for treating obstructive sleep apnea (OSA): the weight-loss drug Zepbound. In a news release published Dec. 20, the FDA.

FDA 243
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The Sun Has Started to Set on the Rare Pediatric Disease Priority Review Voucher Program – But It Can Still be Saved

FDA Law Blog: Drug Discovery

By Mark A. Tobolowsky & Frank J. Sasinowski The Winter Solstice, signifying the shortest day of the year, was Saturday, December 21. Although the earliest sunset of the year was actually in early December, this day also marked another premature sunset the beginning of the end of the rare pediatric disease priority review voucher program. As we blogged recently, the program has had scheduled sunset dates from its very beginning, which have been repeatedly extended.

Disease 59
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Enabling AWS IAM DB Authentication

Perficient: Drug Development

IAM Database Authentication lets you log in to your Amazon RDS database using your IAM credentials. This makes it easier to manage access, improves security, and provides more control over who can do what. Let’s look at how to set it up and use it effectively. Objective: IAM DB Authentication improves security, enables centralized user management, supports auditing, and ensures scalability for database access.

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Create and Manage Microsoft Teams and Channels with PowerShell

Perficient: Drug Development

In this blog, we will walk through the process of creating a Team, adding Team Channels, and managing owners and members within Microsoft Teams using PowerShell scripts. Youll learn how to automate the creation of Teams, organize them with different channels, and efficiently manage user roles and permissions, such as assigning ownership or membership.

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