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Researchers show that early-onset colorectal cancer (CRC) incidence rates are rising in 27 of 50 countries/territories worldwide, 20 of which have either exclusive or faster increases for early-onset disease. In 14 countries, including the United States, rates are increasing in young adults while stabilizing in those 50 years and older.
The biopharmaceutical industry has witnessed a significant surge in the number of therapeutic molecules in development, leading to a corresponding increase in the number of contract development and manufacturing organizations (CDMOs). This growth has created a competitive landscape where pharmaceutical companies must carefully evaluate and select the right CDMO partner to ensure the success of their projects.
Is it possible to pass on the effects of malnutrition? A new animal study found that a protein-deficient diet in one generation created related health risks -- lower birth-weight, smaller kidneys -- in offspring that lasted four generations.
The pharmaceutical industry, particularly the generic drug sector, faces significant challenges in adopting sustainable practices. As the world grapples with the consequences of climate change, companies must adapt their operations to reduce environmental impacts while maintaining cost-effectiveness and regulatory compliance. This article outlines key considerations and strategies for developing a sustainable generic drug development strategy.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
A new class of magnetism called altermagnetism has been imaged for the first time in a new study. The findings could lead to the development of new magnetic memory devices with the potential to increase operation speeds of up to a thousand times.
In recent years, regulatory focus has shifted from sensitivity to accuracy, marking a pivotal change in how we approach toxicological assessments. While sensitivity remains essential, our growing understanding of toxicology highlights the critical importance of precise target analysis. This shift in focus is especially critical in toxicology, where accurate target analysis plays a vital role in identifying toxic effects and ensuring patient safety, particularly as the field transitions from trad
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
In recent years, regulatory focus has shifted from sensitivity to accuracy, marking a pivotal change in how we approach toxicological assessments. While sensitivity remains essential, our growing understanding of toxicology highlights the critical importance of precise target analysis. This shift in focus is especially critical in toxicology, where accurate target analysis plays a vital role in identifying toxic effects and ensuring patient safety, particularly as the field transitions from trad
A new study highlights a hidden challenge of using AI in medical imaging research -- the phenomenon of highly accurate yet potentially misleading results known as 'shortcut learning.' The researchers analyzed thousands of knee X-rays and found that AI models can 'predict' unrelated and implausible traits such as whether patients abstained from eating refried beans or beer.
Inflammatory bowel disease (IBD) is rising in prevalence across the globe, as the number of individuals diagnosed with the condition has increased by 95% since 1990. 1 Despite the recent scientific advances in therapies for IBD, including ulcerative colitis and Crohns disease, there are still persistent unmet medical needs due to the complexity and chronic nature of these conditions.
Scientists' findings in mice could translate into a radical, needle-free vaccination approach that would also eliminate reactions including fever, swelling and pain.
#WhyIScience Q&A: A computational biologists world travels have shaped her approach to research By Corie Lok December 11, 2024 Breadcrumb Home #WhyIScience Q&A: A computational biologists world travels have shaped her approach to research Wolu Chukwu talks about how she brings a community-first focus to her work in cancer genetics. By Corie Lok December 11, 2024 Credit: Allison Colorado, Broad Communications Wolu Chukwu is a computational biologist studying cancer genetics at Broad.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
An interdisciplinary team has created tiny bubble-like microrobots that can deliver therapeutics right where they are needed and then be absorbed by the body.
Flutter’s versatility and powerful UI capabilities have made it a leading choice for building cross-platform mobile apps. However, its resource-intensive nature requires developers to fine-tune performance to create smooth, responsive, and memory-efficient apps. This guide compiles essential optimization techniques to help you craft a stellar Flutter experience. 1.
Recycling all the human and livestock feces and urine on the planet would contribute substantially to meeting the nutrient supply for all crops worldwide, thereby reducing the need to mine fertilizers such as phosphorus and dramatically reducing the dependency on fossil fuels, according to a global analysis of nutrient recycling.
Drug Pricing, Global Diversity Strategies, & Emerging AI Applications Each year, we compile our predictions to provide life sciences, pharmaceutical, and healthcare organizations with a comprehensive look at emerging industry trends and dynamics to help them prepare for the year ahead. These forecasts highlight the key changes poised to transform the healthcare and pharma landscapes.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
A groundbreaking study has shed light on how lizards and snakes -- the most diverse group of land vertebrates with nearly 12,000 species -- have evolved remarkably varied jaw shapes, driving their extraordinary ecological success.
The review discusses the systemic development of selective inhibitors for Mtb -DHFR as antitubercular agents and their designing strategies. The study also explores and compiles the latest patents and clinical trial data into a single platform to help develop selective Mtb -DHFR inhibitors for effective tuberculosis treatment. ABSTRACT Tuberculosis (TB) is an obstinate and infectious disease requiring a relatively longer treatment duration than other bacterial infections.
Stunning new photographs by a team of astronomers have revealed a newly forming galaxy that looks remarkably similar to a young Milky Way. The extraordinary images give us an unprecedented picture of what our own galaxy might have looked like when it was being born.
Achieving operational excellence in a Contract Development and Manufacturing Organization (CDMO) is crucial to ensure the quality and consistency of products and services. This can be achieved by implementing robust controls, optimizing workflows, and fostering a culture of continuous improvement. Here are some key strategies to achieve operational excellence in a CDMO: Implementing Robust Controls Compliance with Regulatory Guidelines : Ensure compliance with strict regulatory standards set by
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
A new study shows that long-term exposure to air pollution contributes to millions of deaths in India. The research emphasizes the need for stricter air quality regulations in the country.
Generic drugs play a crucial role in providing affordable healthcare options to millions of patients worldwide. One of the key tools that generic drug manufacturers rely on to navigate the complex regulatory environment is the FDA’s Product Specific Guidances (PSGs). These guidances serve as a roadmap for companies looking to develop generic versions of brand-name drugs, offering invaluable insights into the FDA’s expectations for demonstrating bioequivalence and ensuring product qua
How can we explain the morphological diversity of living organisms? Although genetics is the answer that typically springs to mind, it is not the only explanation. By combining observations of embryonic development, advanced microscopy, and cutting-edge computer modelling, a multi-disciplinary team demonstrates that the crocodile head scales emerge from the mechanics of growing tissues, rather than molecular genetics.
On Wednesday, December 11, Hyman, Phelps & McNamara, P.C. (HPM) and Riparian LLC will co-host a webinar on an important CMS rule imposing penalties for misclassification of drugs and other reporting errors under the Medicaid Drug Rebate Program. (See our post on this rule here.) The Webinar will explore the CMS rule and provide actionable recommendations for manufacturers on how to navigate the new requirements.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Now is the time for retail giants to knock Santa off his pedestal and to do it, they can become reverse logistics experts. The younger generations have become accustomed to trying products before they buy them and being able to return them conveniently when products do not live up to their expectations. In both these areas, the good old Saint Nick, who has reigned over the holiday season for generations, is now falling short on customers demands.
This week, Im rerunning some popular posts while I prepare for Fridays Drug Channels Outlook 2025 live video webinar. Click here to see the original post. In my recent The 340B Drug Pricing Program: Trends, Controversies, and Outlook video webinar, I provided an update on the economics of the 340B program, reviewed the multiple controversies surrounding the programs operations, discussed state and federal legislation, and analyzed how the Inflation Reduction Act of 2022 (IRA) will alter the 340B
The U.S. healthcare insurance industry stands at a pivotal moment. Amid rising costs, regulatory pressures, and an increasing demand for personalized care, healthcare payers must reinvent themselves. Generative AI (GenAI) offers a transformative pathway, enabling payers to transition from reactive cost management to proactive health enablement and strategic value creation.
The impact of immunotherapy in oncology over recent years is undeniable. Novel therapeutic approaches have led to durable responses in some patients with metastatic disease, with some even experiencing results similar to a cure. Yet they do not work for everyone, and we still have a long way to go to fully harness the immune systems ability to fight cancer.
Introduction Redux, a JavaScript application’s predictable state container, has emerged as a key component for React application state management. To make sure that your state management functions as intended, it is essential to test your Redux code. We’ll look at methods and resources for testing Redux apps in this extensive article. Why Test Redux?
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