Mon.Nov 11, 2024

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On Wall Street, ‘flat out’ failure of AbbVie schizophrenia drug leaves analysts stunned

BioPharma Drive: Drug Pricing

Negative drug results cost AbbVie billions of dollars in market value and convinced analysts that Bristol Myers had placed a better bet in buying Karuna Therapeutics.

Drugs 315
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Storm in a laser beam: Physicists create 'light hurricanes' that could transport huge amounts of data

Science Daily: Pharmacology News

The discovery, centred around controlling tiny hurricanes of light and electromagnetic fields, could revolutionise how much information we can deliver over cables.

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Weight Loss Meds Help Stroke Survivors Prevent Stroke Recurrence, Death

Drugs.com

MONDAY, Nov. 11, 2024 -- The weight-loss drug Ozempic can help reduce stroke patients’ risk of a heart attack or death, a new study says.GLP-1 weight-loss drugs like Ozempic or SGLT2 diabetes medications like Jardiance or Farxiga both helped p.

Drugs 289
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Asthma may place children at risk of memory difficulties

Science Daily: Pharmacology News

Asthma is associated with memory difficulties in children, and early onset of asthma may exacerbate memory deficits, according to a new study.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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FDA approves new CAR-T competitor to Gilead’s Tecartus

BioPharma Drive: Drug Pricing

Developer Autolus set a list price of $525,000 for its new cell therapy, which it will sell for a type of leukemia under the brand name Aucatzyl.

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FDA lifts pause on Novavax flu vaccine trials

BioPharma Drive: Drug Pricing

After an investigation, the agency concluded that a case of muscle weakness in one of Novavax’s trials was actually ALS and unrelated to vaccination.

Vaccine 256
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Was 'Snowball Earth' a global event? Study delivers best proof yet

Science Daily: Pharmacology News

A series of rocks hiding around Colorado's Rocky Mountains may hold clues to a frigid period in Earth's past when glaciers several miles thick covered the entire planet.

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Report Finds Big Disparities in Americans' Well-Being by Region

Drugs.com

MONDAY, Nov. 11, 2024 -- Americans’ well-being varies widely between different regions of the nation, a new study reports.People in the southern U.S., Appalachia and the Rust Belt states score lowest on the Human Development Index (HDI), a c.

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Swirling polar vortices likely exist on the Sun

Science Daily: Pharmacology News

Like the Earth, the Sun likely has swirling polar vortices, according to new research. But unlike on Earth, the formation and evolution of these vortices are driven by magnetic fields.

Research 282
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Diabetes & Kidney Trouble Can Bring Heart Disease Decades Earlier

Drugs.com

MONDAY, Nov. 11, 2024 -- People with both type 2 diabetes and chronic kidney disease face a heart health double-whammy, a new study says.Men with both diabetes and kidney disease will develop heart health problems 28 years earlier than those.

Disease 246
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Compact error correction: Towards a more efficient quantum 'hard drive'

Science Daily: Pharmacology News

Two quantum information theorists have solved a decades-old problem that will free up quantum computing power.

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Could Asthma Harm a Child's Memory Skills?

Drugs.com

MONDAY, Nov. 11, 2024 -- Asthma is associated with memory problems in children, a new study has found. Further, the early onset of asthma might worsen potential memory deficits in kids, researchers found. This is the first study to make such a.

Research 246
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Super microscope shows nanoscale biological process for the first time

Science Daily: Pharmacology News

A new microscope is capable of live imaging of biological processes in such detail that moving protein complexes are visible.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Hourglass-Shaped Stent Might Ease Tough-to-Treat Angina

Drugs.com

MONDAY, Nov. 11, 2024 -- Recurring angina chest pain in people with a certain type of heart disease can be tough to treat, but a new hourglass-shaped stent could be a real advance, researchers report.People with what's known as microvascular.

Disease 246
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A milestone in the study of octopus arms

Science Daily: Pharmacology News

Research describes a computational model that captures the intricate muscular architecture of an octopus arm.

Research 264
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Obesity-Linked Heart Deaths Nearly Tripled in U.S. Over Past Two Decades

Drugs.com

MONDAY, Nov. 11, 2024 -- Lives lost to obesity-related heart disease have nearly tripled over the past twenty years, a new study reports.Heart disease deaths linked to obesity increased 2.8-fold between 1999 and 2020, according to findings.

Disease 246
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Redefining Acceleration of the Drug Development Journey

PPD

It is hard to ignore some of the most pressing, long-term trends driving the push to accelerate innovation and progress in drug development. From an aging population increasing health care demand to urgent, unmet medical needs, there are clear drivers to advance safe and effective medicines to patients faster than ever. According to the United Nation’s 2024 World Population Prospects data, the global population of those 65 years old and over will grow from 0.8 billion in 2023 to 1.2 billion in 2

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Have an Implanted Defibrillator? Triple-Digit Heatwaves Could Pose Danger

Drugs.com

MONDAY, Nov. 11, 2024 -- Thousands of Americans with heart trouble have small implanted defibrillators, to help regulate their heartbeat and keep cardiac events at bay. But new research finds that on extremely hot days, people with the devices face.

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Managing Drug Patent Portfolios Effectively

Drug Patent Watch

Effective management of drug patent portfolios is crucial for pharmaceutical companies to maintain market exclusivity, protect revenue streams, and drive innovation. A robust patent strategy aligned with business goals is essential for maximizing value and staying competitive in the pharmaceutical landscape.

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How ADHD May Influence a Child's Weight

Drugs.com

MONDAY, Nov. 11, 2024 -- Attention-deficit/hyperactivity disorder can influence a child’s weight in ways that will shape their long-term health, a new study says.Kids with ADHD tend to have lower birth weight, which increases their risk of d.

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AbbVie’s $9B bet collapses as closely watched schizophrenia drug fails studies

BioPharma Drive: Drug Pricing

Shares in AbbVie slumped Monday after the company disclosed its psychiatric medicine emraclidine didn’t best placebo in two Phase 2 trials.

Trials 148
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Bystanders More Readily Perform CPR If 911 Operator Instructs

Drugs.com

MONDAY, Nov. 11, 2024 -- You encounter someone collapsed on the sidewalk and quickly dial 911. Whether or not the operator instructs you on how to deliver cardiopulmonary resuscitation (CPR) could mean life or death, especially if the victim is.

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Cigna confirms it is not pursuing Humana acquisition

BioPharma Drive: Drug Pricing

The formal denial comes after Cigna CEO David Cordani tried to push back on persistent speculation of a Humana merger earlier this fall.

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Biomarker Analysis in Drug Development: Boosting Precision Medicine

Crown Bioscience

Introduction to Biomarkers in Drug Development Biomarkers have become a cornerstone in the advancement of modern drug development and precision medicine. A biomarker, short for biological marker, is a measurable indicator of some biological state or condition. These can be proteins, genes, or other molecules that signal an abnormal or normal process in the body.

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Thinking inside the box: How SmartLabs is driving new collaborations to support the life science industry in global innovation hubs

BioPharma Drive: Drug Pricing

Seamlessly scale and adapt to match the rapid pace and complexity of modern science.

Science 130
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Einstein's equations collide with the mysteries of the Universe

Science Daily: Pharmacology News

Why is the expansion of our Universe accelerating? Twenty-five years after its discovery, this phenomenon remains one of the greatest scientific mysteries. Solving it involves testing the fundamental laws of physics, including Albert Einstein's general relativity. Researchers compared Einstein's predictions with data from the Dark Energy Survey. Scientists discovered a slight discrepancy that varies with different periods in cosmic history.

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