Mon.May 20, 2024

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AI collaboration shows success for novel heart failure target  

Drug Discovery World

AstraZeneca has added a novel target for heart failure to its discovery portfolio through its collaboration with BenevolentAI. This novel target for heart failure was discovered using BenevolentAI’s AI-drug discovery platform and experimentally validated by AstraZeneca. This is the first target to be selected from the extended collaboration with AstraZeneca, highlighting continued positive progress in the field of target identification.

Disease 148
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Stomach Paralysis Risk May Rise in People Taking Ozempic and Similar Drugs

Drugs.com

MONDAY, May 20, 2024 -- New, real-world research confirms that the blockbuster weight-loss drugs that millions of Americans have been taking to shed pounds can trigger stomach paralysis in some patients.“Although these drugs do work and should be.

Drugs 133
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Technology: Artificial intelligence, machine learning and lab automation

Drug Discovery World

In this free webinar, hosted by DDW and sponsored by Benchling, you will learn about technology through the lens of artificial intelligence (AI), machine learning and lab automation. You will hear from Jonathan Wingfield, Principal Scientist at AstraZeneca; Abraham Heifets, CEO at Atomwise; Raminderpal Singh, AI Expert at HitchhikersAI; and Helen Liu-Mayo, Product Manager, Machine Learning at Benchling.

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'Vigorous melting' at Antarctica's Thwaites 'Doomsday' Glacier

Science Daily: Pharmacology News

Glaciologists show evidence of warm ocean water intruding kilometers beneath grounded ice at Thwaites Glacier in West Antarctica. The findings suggest that existing climate models are underestimating the impact of ocean and ice interactions in future sea level rise projections.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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GLP-1 receptor agonists market to reach $125 billion by 2033

Drug Discovery World

Glucagon-like peptide-1 (GLP-1) receptor agonist sales for the type 2 diabetes and obesity markets are forecast to reach over $125 billion in the seven major markets (7MM) by 2033, according to analysts GlobalData. GLP-1 receptor agonists like Ozempic (semaglutide) are a class of incretin mimetic medicines for the treatment of type 2 diabetes and obesity.

Marketing 130
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Brain 'assembloids' mimic human blood-brain barrier

Science Daily: Pharmacology News

Major advance promises to accelerate the understanding and improved treatment of a wide range of brain disorders, including stroke, cerebral vascular disorders, brain cancer, Alzheimer's disease, Huntington disease, Parkinson's disease, and other neurodegenerative conditions.

Disease 128

More Trending

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Record low Antarctic sea ice 'extremely unlikely' without climate change

Science Daily: Pharmacology News

Scientists have found that the record-low levels of sea ice around Antarctica in 2023 were extremely unlikely to happen without the influence of climate change. This low was a one-in-a-2000-year event without climate change and four times more likely under its effects.

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Therapies designed to dismantle cancer’s escape mechanisms show promise for patients

BioPharma Drive: Drug Pricing

Hear from IO Biotech CEO Dr. Mai-Britt Zocca about the potential of therapeutic vaccines to strip the defenses used by cancer cells to keep the immune system at bay.

Therapies 113
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1 in 4 Parents Say Their Teen Drinks Caffeine Daily

Drugs.com

MONDAY, May 20, 2024 -- Many teens are spending their days buzzed on caffeine, with their parents mostly unaware of the potential risks, a new national poll says.A quarter of parents reported that caffeine is basically part of their teen’s daily.

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Webb Telescope offers first glimpse of an exoplanet's interior

Science Daily: Pharmacology News

A surprisingly low amount of methane and a super-sized core hide within the cotton candy -- like planet WASP-107 b.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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New Blood Test Could Spot Dangerous Type of Stroke

Drugs.com

MONDAY, May 20, 2024 -- When a stroke hits, "time is brain," doctors say, with neurons beginning to die off in minutes. Quickly figuring out which type of stroke a patient has been hit with is crucial. Now, an experimental blood test might speed.

Doctors 105
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Innovative 3D printing could revolutionize treatment for cataracts and other eye conditions

Science Daily: Pharmacology News

Rsearchers have developed the first 3D printable ocular resins, marking a significant breakthrough in manufacturing specialist lenses for implantation in the human eye.

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BIO to restructure, lay off staff in shakeup of lobbying group

BioPharma Drive: Drug Pricing

Thirty employees will leave as part of the reorganization, which the group said is meant to bring "stronger focus and greater impact" to its work.

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Meerkat chit-chat

Science Daily: Pharmacology News

Researchers unravel the vocal interactions of meerkat groups and show they use two different types of interactions to stay in touch.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Could Infertility Treatment Raise Postpartum Heart Risks?

Drugs.com

MONDAY, May 20, 2024 -- Women treated for infertility were twice as likely as those who conceived naturally to be hospitalized with heart disease within a year of delivery, recent research shows.They are particularly likely to land in the hospital.

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Forbion-backed biotech Progentos debuts with $65M for MS drug

BioPharma Drive: Drug Pricing

Progentos says the money will go toward expanding its pipeline and pushing an experimental treatment for multiple sclerosis through "proof of concept” testing.

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World leaders still need to wake up to AI risks

Science Daily: Pharmacology News

Leading AI scientists are calling for stronger action on AI risks from world leaders, warning that progress has been insufficient since the first AI Safety Summit six months ago. Then, the world's leaders pledged to govern AI responsibly. However, twenty-five of the world's leading AI scientists say not enough is actually being done to protect us from the technology's risks.

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European Commission, in ‘unprecedented’ move, declines to revoke approval of PTC Duchenne drug

BioPharma Drive: Drug Pricing

Rather than endorse the recommendation of the EMA, the commission called for a new review for Translarna that considers “the totality of the evidence” compiled to date.

Drugs 67
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Fertility Treatments Safe for Breast Cancer Survivors With Cancer-Linked Genes

Drugs.com

MONDAY, May 20, 2024 -- Fertility treatments such as in vitro fertilization (IVF) and other methods don't boost the odds for tumor recurrence in young women who've survived breast cancer and carry the BRCA cancer genes, a reassuring, new report.

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Dyne shares jump on trial data for muscle disease drugs

BioPharma Drive: Drug Pricing

Updated study results for the biotech’s medicines for myotonic dystrophy Type 1 and Duchenne muscular dystrophy appeared to impress analysts and investors on Wall Street.

Disease 62
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New patent for Ani Pharms drug PURIFIED CORTROPHIN GEL

Drug Patent Watch

Annual Drug Patent Expirations for PURIFIED+CORTROPHIN+GEL Purified Cortrophin Gel is a drug marketed by Ani Pharms and is included in one NDA. It is available from one supplier.

Drugs 59
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Tracking Exercise by Steps or Minutes? Study Finds Either Method Boosts Health

Drugs.com

MONDAY, May 20, 2024 -- Some folks like to count their daily steps, while others prefer exercising for a certain amount of time during a day or a week.Luckily, either approach boosts health, a new study finds.Exercise targets based on either step.

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New patent for Baxter Hlthcare drug NOURESS

Drug Patent Watch

Annual Drug Patent Expirations for NOURESS Nouress is a drug marketed by Baxter Hlthcare Corp and is included in one NDA. It is available from one supplier.

Drugs 59
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In a Shift, Pediatricians' Group Says Breastfeeding Safe When HIV-Positive Mom Is Properly Treated

Drugs.com

MONDAY, May 20, 2024 -- The nation’s top pediatrics group has reversed its decades-old position on HIV-positive mothers breastfeeding their infants.The American Academy of Pediatrics now says it’s generally safe for moms with HIV to breastfeed.

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New patent expiration for Ge Healthcare drug VIZAMYL

Drug Patent Watch

Annual Drug Patent Expirations for VIZAMYL Vizamyl is a drug marketed by Ge Healthcare and is included in one NDA. It is available from one supplier.

Drugs 59
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Catherine Breen

Broad Institute

Catherine Breen By Rose Circeo May 20, 2024 Catherine Breen Chief of Staff, Executive Director of Strategic Initiatives Catherine Breen is the chief of staff and executive director of strategic initiatives at the Broad Institute of MIT and Harvard. The chief of staff plays a critical role as strategic thought partner to the institute Director, key partner to the chief operating officer, and close collaborator with other members of the executive and scientific leadership teams.

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New patent expiration for Alexza Pharms drug ADASUVE

Drug Patent Watch

Annual Drug Patent Expirations for ADASUVE Adasuve is a drug marketed by Alexza Pharms and is included in one NDA. It is available from one supplier.

Drugs 59
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Scientific leadership team

Broad Institute

Scientific leadership team By Rose Circeo May 20, 2024 Breadcrumb Home People Scientific leadership team The Scientific Leadership Team is led by Founding Director Eric S. Lander (chair), with Core Institute Member Feng Zhang (vice-chair). This team of scientists stewards the Broad’s scientific vision, directions, and execution. The SLT identifies promising directions, gathers perspectives, and develops plans for consideration by the Broad community.

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A Beginner’s Guide to C# Selenium Automation: Step-by-Step Tutorial

Perficient: Drug Development

Are you interested in learning more about C# automation but need help determining where to begin? Do not be alarmed! In this step-by-step tutorial, we’ll walk you through starting from scratch with C# automation. After completing this course, you’ll have a strong basis for effectively automating activities with C#. Step 1: Setting Up Your Development Environment Before we begin coding, let’s ensure that you have the necessary tools set up on your system.

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The Transformative Benefits of Microneedling with PRP

Olympian Clinical Research

Microneedling with PRP (Platelet-rich Plasma) has quickly gained popularity in the world of skincare due to its impressive results. At Academic Alliance in Dermatology , we believe in providing treatments that enhance natural beauty. Let’s explore what microneedling with PRP entails and why it could be the perfect addition to your skincare routine. What is Microneedling with PRP?

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Perficient to Host Workshop at B2B Connect

Perficient: Drug Development

From June 10-12, B2B Connect will be in San Diego, and Perficient will be hosting a workshop entitled “How to Prioritize Your Direct-to-Consumer Capabilities: What Should I Do Now vs. Next?” This workshop will discuss how the direct-to-consumer (D2C) business model continues to gain momentum, with new brands and established players continually entering the market; how this trend presents more traditional companies with opportunities to harness the expanding online traffic and drive growth by rai

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Distinguishing the Roles of Preclinical vs. Clinical CROs in Clinical Research

Vial

Distinguishing the Roles of Preclinical vs. Clinical CROs in Clinical Research Randomized clinical trials are the gold-standard of evidence-based medicine, representing the culmination of the long, arduous drug development pipeline. In the field of clinical research , this pipeline can be broken down into several stages and processes specifically designed to rigorously validate the safety and efficacy of new drugs and treatments.

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How to Decentralize Cell and Gene Therapy Treatments

thought leadership

The Challenge: CAGT Treatments Require Time and Lack Availability Persons diagnosed with life threatening diseases which are now treatable with cell and gene therapies (CAGT) often needed to wait for a significant amount of time for treatment due to lack of availability.

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A Memorable Trip to Munnar with Team

Perficient: Drug Development

One fine evening, amidst our busy work life cycle, the project team at Perficient decided to take a break to relax and enjoy nature for our well-being. It all started with a casual conversation during a lunch break. Together, we planned a wonderful trip to Munnar, a breathtaking hill station nestled in the Western Ghats of Kerala, India. Join us as we share our adventure-filled trip to Munnar.

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