Chemical Biology and Drug Design

JUNE 2, 2024

The antiproliferative and pro-apoptotic functions of quercetin in breast cancer cell lines are mediated by targeting and suppressing PI3K/Akt/mTOR/PTEN signal transduction. Abstract Recently, natural compounds such as quercetin have gained an increasing amount of attention in treating breast cancer. However, the exact mechanisms responsible for the antiproliferative functions of quercetin are not completely understood.

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Treatment Research 100

BioPharma Drive: Drug Pricing

JUNE 2, 2024

Study results showed the antibody-drug conjugate helped stave off disease progression better than a standard treatment. But eye-related side effects remained common.

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Drugs Treatment Disease 120

Drugs.com

JUNE 2, 2024

SUNDAY, June 2, 2024 -- Cerebral aneurysms: For most people, the word signals a sudden, fatal brain bleed that seemingly comes out of nowhere. However, an expert at Penn State Health says that in many cases these brain blood vessel ruptures are.

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BioPharma Drive: Drug Pricing

JUNE 2, 2024

The findings, from a trial testing Imfinzi in limited-stage small cell lung cancer, could help AstraZeneca expand the drug's use.

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Trials Drugs 120

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Drug Patent Watch

JUNE 2, 2024

Brivaracetam is the generic ingredient in two branded drugs marketed by Ucb Inc, Aurobindo Pharma Ltd, Lupin Ltd, Sunshine, and Zydus Pharms and, and is included in seven NDAs.

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Drugs Marketing 59

BioPharma Drive: Drug Pricing

JUNE 2, 2024

The results are a step forward for antibody-drug conjugates, which Enhertu makers AstraZeneca and Daiichi Sankyo see replacing chemo in many tumors.

Drugs 69

Drugs 69

Perficient: Drug Development

JUNE 2, 2024

Automation is an essential element in the dynamic field of software development and testing, as it helps achieve uniformity and efficiency. Selenium, an open-source web browser automation tool, has greatly enhanced the testing process for many developers and testers. However, adding artificial intelligence (AI) can improve Selenium’s performance even more.

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Research 40

Drug Patent Watch

JUNE 2, 2024

This chart shows the drugs with the most supplementary protection certificates (SPCs).

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Drugs Pharmaceuticals 59

FDA Law Blog: Drug Discovery

JUNE 2, 2024

By Adrienne R. Lenz, Principal Medical Device Regulation Expert — FDA’s Office of Women’s Health (OWH) recently celebrated its 30th anniversary. This office was formed in 1994 to promote the inclusion of women in clinical trials and to provide leadership on topics related to the health of women. Given that FDA was founded in 1906 and the Federal Food, Drug and Cosmetic Act went into effect in 1938, the OWH’s thirty years of existence, while an important milestone, constitutes a very small amou

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FDA Clinical Trials Regulations Trials 64

Codon

JUNE 2, 2024

Today we launch Issue 03 of Asimov Press. Read our full Editors’ Note and preview upcoming articles by clicking here. Read this article on our website by clicking here. It was 1905, and the French biologist Lucien Cuénot had a puzzle on his hands. He had been breeding mice in an attempt to decipher the patterns of coat color inheritance, but one of his crosses wasn’t behaving as expected.

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Laboratories Research Disease Science 123

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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