Sun.Jun 02, 2024

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Quercetin inhibits breast cancer cell proliferation and survival by targeting Akt/mTOR/PTEN signaling pathway

Chemical Biology and Drug Design

The antiproliferative and pro-apoptotic functions of quercetin in breast cancer cell lines are mediated by targeting and suppressing PI3K/Akt/mTOR/PTEN signal transduction. Abstract Recently, natural compounds such as quercetin have gained an increasing amount of attention in treating breast cancer. However, the exact mechanisms responsible for the antiproliferative functions of quercetin are not completely understood.

Treatment 100
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GSK builds case for return of multiple myeloma drug Blenrep

BioPharma Drive: Drug Pricing

Study results showed the antibody-drug conjugate helped stave off disease progression better than a standard treatment. But eye-related side effects remained common.

Drugs 118
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What Is a Cerebral Aneurysm? What Are the Signs?

Drugs.com

SUNDAY, June 2, 2024 -- Cerebral aneurysms: For most people, the word signals a sudden, fatal brain bleed that seemingly comes out of nowhere. However, an expert at Penn State Health says that in many cases these brain blood vessel ruptures are.

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AstraZeneca immunotherapy extends survival by two years in rarer type of lung cancer

BioPharma Drive: Drug Pricing

The findings, from a trial testing Imfinzi in limited-stage small cell lung cancer, could help AstraZeneca expand the drug's use.

Trials 117
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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New tentative approval for Annora Pharma drug brivaracetam

Drug Patent Watch

Brivaracetam is the generic ingredient in two branded drugs marketed by Ucb Inc, Aurobindo Pharma Ltd, Lupin Ltd, Sunshine, and Zydus Pharms and, and is included in seven NDAs.

Drugs 59
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With new Enhertu data, an ADC could overtake chemo in breast cancer

BioPharma Drive: Drug Pricing

The results are a step forward for antibody-drug conjugates, which Enhertu makers AstraZeneca and Daiichi Sankyo see replacing chemo in many tumors.

Drugs 69

More Trending

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Enhancing Selenium with AI Capabilities: Integrating Image Recognition, NL, and ML

Perficient: Drug Development

Automation is an essential element in the dynamic field of software development and testing, as it helps achieve uniformity and efficiency. Selenium, an open-source web browser automation tool, has greatly enhanced the testing process for many developers and testers. However, adding artificial intelligence (AI) can improve Selenium’s performance even more.

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Which drugs have supplementary protection certificates in the most countries?

Drug Patent Watch

This chart shows the drugs with the most supplementary protection certificates (SPCs).

Drugs 59
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Women’s Health a Focus for FDA and Biden Administration

FDA Law Blog: Drug Discovery

By Adrienne R. Lenz, Principal Medical Device Regulation Expert — FDA’s Office of Women’s Health (OWH) recently celebrated its 30th anniversary. This office was formed in 1994 to promote the inclusion of women in clinical trials and to provide leadership on topics related to the health of women. Given that FDA was founded in 1906 and the Federal Food, Drug and Cosmetic Act went into effect in 1938, the OWH’s thirty years of existence, while an important milestone, constitutes a very small amou

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Origins of the Lab Mouse

Codon

Today we launch Issue 03 of Asimov Press. Read our full Editors’ Note and preview upcoming articles by clicking here. Read this article on our website by clicking here. It was 1905, and the French biologist Lucien Cuénot had a puzzle on his hands. He had been breeding mice in an attempt to decipher the patterns of coat color inheritance, but one of his crosses wasn’t behaving as expected.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.