Tue.Oct 22, 2024

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Paws of polar bears sustaining ice-related injuries in a warming Arctic

Science Daily: Pharmacology News

Polar bears in some parts of the high Arctic are developing ice buildup and related injuries to their feet. The changes appear to be an unexpected consequence of climate change, related to changing conditions in a warming Arctic.

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RNA editing: emerging from CRISPR’s shadow

BioPharma Drive: Drug Pricing

Early study data from Wave Life Sciences suggests how editing RNA may yield viable medicines. Large and small drugmakers say such results are just the start.

RNA 353
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Bilingualism may maintain protection against Alzheimer's

Science Daily: Pharmacology News

In a study, researchers use neuroimaging methods to examine brain resilience in regions of the brain linked to language and aging. They found that the hippocampus in bilinguals with Alzheimer's disease was noticeably larger than those who were monolingual when matched for age, education, cognitive function and memory, which suggests that there may be some form of brain maintenance related to bilingualism.

Disease 322
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Fatal Opioid-Meth Overdoses Have Fallen in U.S. by More Than a Third

Drugs.com

TUESDAY, Oct. 22, 2024 -- Expanded access to addiction treatment and the overdose-reversal med naloxone likely prompted a 37% reduction in OD deaths linked to opioids taken with meth or other stimulant drugs, a new study suggests.OD death rates.

Treatment 290
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Wearable cameras allow AI to detect medication errors

Science Daily: Pharmacology News

A team of researchers says it has developed the first wearable camera system that, with the help of artificial intelligence, detects potential errors in medication delivery. In a test, the video system recognized and identified, with high proficiency, which medications were being drawn in busy clinical settings. The AI achieved 99.6% sensitivity and 98.8% specificity at detecting vial-swap errors.

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More Trending

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At-Home Brain Stimulation Treatment Can Safely Ease Depression

Drugs.com

TUESDAY, Oct. 22, 2024 -- At-home brain stimulation therapy can safely and effectively treat severe to moderate depression, a new clinical trial shows.Rates of treatment response and depression remission were three times higher in people receiving.

Treatment 279
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Geometric mechanics shape the dog's nose

Science Daily: Pharmacology News

The noses of many mammals, such as dogs, ferrets and cows, feature grooves forming a multitude of polygons. A team has analyzed in detail how these patterns form in the embryo using 3D imaging techniques and computer simulations. The researchers discovered that differential growth of the skin tissue layers leads to the formation of domes, which are mechanically supported by the underlying blood vessels.

Research 270
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Light Therapy Might Help Ease 'Dry' Form of Macular Degeneration

Drugs.com

TUESDAY, Oct. 22, 2024 -- Light therapy could be a useful treatment for the most common form of age-related macular degeneration, a new study says.The therapy, called photobiomodulation or “red light” therapy, can reduce the risk of vision loss and.

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Starboard makes case for change at Pfizer, citing research, M&A missteps

BioPharma Drive: Drug Pricing

The activist investor claims Pfizer failed to capitalize on the windfall earned from its COVID-19 vaccine and, in the process, destroyed tens of billions of dollars in market value.

Research 206
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Listeria Danger Spurs Nationwide Recall of Frozen Waffles

Drugs.com

TUESDAY, Oct. 22, 2024 -- Treehouse Foods Inc. has recalled dozens of frozen waffle products because of potential listeria contamination.The recalled products were distributed throughout the United States and Canada and packed in various formats.

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Otsuka’s startup bet pays off with kidney disease drug results

BioPharma Drive: Drug Pricing

A medicine the pharma acquired in a $430 million buyout of Visterra in 2018 succeeded in a Phase 3 trial in IgA nephropathy, a crowded corner of drug research.

Disease 156
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Washington Becomes 6th State to Report Bird Flu in Humans

Drugs.com

TUESDAY, Oct. 22, 2024 (HealthDayNews) -- Four farm workers who helped cull poultry on an commercial egg farm in Washington are presumed to have been infected with bird flu, making that state the sixth in the country to report human H5N1 infections.

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FDA names Tarver as new head of device center

BioPharma Drive: Drug Pricing

Michelle Tarver will officially replace longtime CDRH leader Jeff Shuren, who stepped down from the role earlier this year.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Cataract Surgery Could Save Your Eyesight and Maybe Your Life

Drugs.com

TUESDAY, Oct. 22, 2024 -- Cataract surgery could restore good vision to older people and by doing so cut their odds for potentially life-threatening falls, a new study finds.Folks who got the surgery had significantly lower odds for bone fractures.

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New JAMA Article Recommends Personal Drug Importation To Help American Patients Afford Prescription Drugs

Policy Prescription

Harvard doctors and public health experts recommend using the website PharmacyChecker.com to find international online pharmacies to order more affordable prescription drugs for personal importation when domestic savings strategies fail. They offer this advice in a new article in the Journal of the American Medical Association. Article Review The article, Strategies to Help Patients Navigate High Prescription Drug Costs , offers very digestible and evidence-driven guidance for clinicians to bet

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Could Caffeine in Pregnancy Help Prevent Cerebral Palsy in Kids?

Drugs.com

TUESDAY, Oct. 22, 2024 -- Experiments in sheep are hinting that doses of caffeine given to women in pregnancy, as well as their newborns after birth, could prevent cerebral palsy.Cerebral palsy is a disabling condition often caused by asphyxia --.

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A Defense of Peer Review

Codon

“I think peer review is, like democracy, bad, but better than anything else." — Timothy Bates, University of Edinburgh I used to see peer review as primarily good — an important gatekeeping process, essential for protecting capital “S” Science from all manner of quackery and nonsense. Looking back, I was clearly naive; plenty of junk science gets published in top journals despite the supposed guardrails of peer review.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Seniors Who Split: Rates of 'Gray Divorce' Have Tripled Since 1990

Drugs.com

TUESDAY, Oct. 22, 2024 -- Baby Boom seniors are divorcing at rates triple that of a few decades ago, a new study has found.“Gray divorce” among folks 65 and older increased to 15% in 2022 from 5% in 1990, according to research from the National Cen.

Research 245
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SAS Proc Transpose In Clinical Trial Programming

Quanticate

A blog article by a member of Quanticate's Clinical Programming team exploring SAS Proc Transpose VS SAS Arrays within Clinical Programming

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Eczema Could Be Linked to Poorer Leg Artery Function

Drugs.com

TUESDAY, Oct. 22, 2024 -- The skin condition eczema appears to be linked to a serious condition that can end in leg amputation, a new study finds.People with eczema are at significantly higher risk of developing peripheral vascular disease.

Disease 244
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The Power of Quarterly Business Reviews: How QBRs Drive Growth and Build Client Relationships

Perficient: Drug Development

Let’s be honest – if you’ve ever thought that Quarterly Business Reviews (or QBRs) were a huge headache, you’re not alone! A QBR is an alignment meeting that’s held every three months between a company like Perficient and its clients. When my director first introduced us to the idea, the team was skeptical. It seemed like just another box to check, and my first few QBRs felt more like a chore than an opportunity.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Black Patients 22% More Likely to Die After Bypass Surgeries

Drugs.com

TUESDAY, Oct. 22, 2024 -- Heart bypass operations have gotten safer, but not everyone is benefiting equally: New data shows that Black patients face a 22% higher odds of dying in the hospital after their surgeries.“We found Black patients who have c.

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Universal Design for Auditory Disabilities – Health System – Enhancing Patient Engagement – 4

Perficient: Drug Development

As we continue our series on auditory disabilities in healthcare, it’s crucial to emphasize the significance of creating an inclusive autograph experience. This principle ensures that all patients, regardless of their auditory capabilities, can fully engage and participate in their healthcare journey through accessible and empowering interactions. The Importance of an Inclusive Autograph Experience Autographs and sign-ins are often the first point of interaction between patients and healthcare p

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Even Hardcore Smokers May Quit If Given Right Tools, Study Finds

Drugs.com

TUESDAY, Oct. 22, 2024 -- Smokers find it easier to quit if they’re automatically offered support, even if they didn't ask for it, a new clinical trial finds.Quit rates were higher among health system patients placed in an “opt-out” program, in whic.

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Injection-Related Injuries in People Who Inject Drugs: Skin and Soft Tissue Infection, Vascular Damage, and Wounds

Common Sense for Drug Policy Blog

Injection-Related Injuries in People Who Inject Drugs: Skin and Soft Tissue Infection, Vascular Damage, and Wounds "Common SSTIs include cellulitis ( Figure 1 ) and skin abscesses ( Figure 2 ), 5 and SSTI is common in PWIDs. In one needle exchange program (N = 152), 17.8% (n = 27) had an active abscess and 19.7% (n = 30) had a chronic wound. 6 The upper extremities were the most common place for an abscess, and the lower extremities were most common for chronic wounds.

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Setting the Standard in CGT

Fierce BioTech

Setting the Standard in CGT With unique perspectives from key opinion leaders, this whitepaper examines the challenges associated with process development and manufacturing of cell and gene therapies. Each chapter pulls into focus a different modality and details how you can accelerate commercialization with end-to-end solutions that prioritize performance and scalability with a simplified path to regulatory approvals. smarcus Tue, 10/22/2024 - 09:34 With unique perspectives from key opinion lea