Wed.May 15, 2024

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A simple quantum internet with significant possibilities

Science Daily: Pharmacology News

It's one thing to dream up a quantum internet that could send hacker-proof information around the world via photons superimposed in different quantum states. It's quite another to physically show it's possible. That's exactly what physicists have done, using existing Boston-area telecommunication fiber, in a demonstration of the world's longest fiber distance between two quantum memory nodes to date.

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Eisai sets new revenue target for Alzheimer’s drug Leqembi

BioPharma Drive: Drug Pricing

The annual forecast, which comes as Eisai and Biogen have begun submitting a more convenient form of Leqembi for approval, looks “more realistic” than previous guidance, according to Jefferies analysts.

Drugs 122
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Animal brain inspired AI game changer for autonomous robots

Science Daily: Pharmacology News

A team of researchers has developed a drone that flies autonomously using neuromorphic image processing and control based on the workings of animal brains. Animal brains use less data and energy compared to current deep neural networks running on GPUs (graphic chips). Neuromorphic processors are therefore very suitable for small drones because they don't need heavy and large hardware and batteries.

Research 138
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Early Hints at a Gene Therapy Cure for Herpes

Drugs.com

WEDNESDAY, May 15, 2024 -- An experimental gene therapy could one day provide a first-ever cure for genital and oral herpes, researchers report.The gene therapy removed 90% or more of oral herpes infection in lab mice, and it also suppressed how.

Therapies 119
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Robots' and prosthetic hands' sense of touch could be as fast as humans

Science Daily: Pharmacology News

Research could pave the way for a prosthetic hand and robot to be able to feel touch like a human hand. The technology could also be used to help restore lost functionality to patients after a stroke.

Research 138
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FDA Approves First Self-Test Collection Kit for HPV

Drugs.com

WEDNESDAY, May 15, 2024 -- The U.S. Food and Drug Administration has approved a kit that will allow women to collect their own vaginal sample for HPV screening, a move that could increase early detection in those at risk for cervical cancer. Women.

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Avian Flu Virus Showing Up in NYC Wild Birds

Drugs.com

WEDNESDAY, May 15, 2024 -- The H5N1 avian flu virus has been discovered in a small number of wild birds in New York City.The highly infectious and severe virus was detected in fecal samples in six New York City birds representing four different.

Virus 115
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Highly pathogenic avian flu detected in New York City wild birds

Science Daily: Pharmacology News

A small number of New York City wild birds carry highly pathogenic H5N1 avian influenza, according to a recent study.

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Could a Low-Cal Keto Diet Help Ease Acne?

Drugs.com

WEDNESDAY, May 15, 2024 -- In a small pilot study, some young women looking to lose weight on a low-calorie keto diet got an unexpected benefit: Their acne began to clear up.“These findings represent an opportunity to control a skin disease that.

Disease 105
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First 'warm-blooded' dinosaurs may have emerged 180 million years ago

Science Daily: Pharmacology News

The ability to regulate body temperature, a trait all mammals and birds have today, may have evolved among some dinosaurs early in the Jurassic period about 180 million years ago. The new study looked at the spread of dinosaurs across different climates on Earth throughout the Mesozoic Era (the dinosaur era lasting from 230 to 66 million years ago), drawing on 1,000 fossils, climate models and the geography of the period, and dinosaurs' evolutionary trees.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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New patent for Mallinckrodt Hosp drug INOMAX

Drug Patent Watch

Annual Drug Patent Expirations for INOMAX Inomax is a drug marketed by Mallinckrodt Hosp and is included in one NDA. It is available from one supplier.

Drugs 105
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Wavefunction matching for solving quantum many-body problems

Science Daily: Pharmacology News

Strongly interacting systems play an important role in quantum physics and quantum chemistry. Stochastic methods such as Monte Carlo simulations are a proven method for investigating such systems. However, these methods reach their limits when so-called sign oscillations occur. This problem has now been solved using the new method of wavefunction matching.

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Report Highlights Big Gaps in Cancer Outcomes Based on Race

Drugs.com

WEDNESDAY, May 15, 2024 -- U.S. cancer death rates are continuing to drop, falling by 33% between 1991 and 2020.However, not all Americans are reaping the benefits from advances in cancer prevention, early detection and treatment, a new report from.

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Robotic 'SuperLimbs' could help moonwalkers recover from falls

Science Daily: Pharmacology News

SuperLimbs, a system of wearable robotic limbs, can physically support an astronaut and lift them back on their feet after a fall, helping them conserve energy for other essential tasks.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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U.S. Drug Overdose Deaths Decline for First Time in 7 Years

Drugs.com

WEDNESDAY, May 15, 2024 -- The relentless rise in deaths from drug overdose in the United States may finally have stalled: New data from 2023 show the first decline in such deaths since 2018."Statistics indicate there were an estimated 107,543 drug.

Drugs 98
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The crystallization of memory: Study reveals how practice forms new memory pathways in the brain

Science Daily: Pharmacology News

A new study has shown that repetitive practice not only is helpful in improving skills but also leads to profound changes in the brain's memory pathways.

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New Blood Test Could Help Spot Preeclampsia in First Trimester

Drugs.com

WEDNESDAY, May 15, 2024 -- Preeclampsia can be a life-threatening complication of pregnancy, but a new blood test can help predict a woman's risk for the condition while she is in her first trimester, the test's maker said Wednesday.It’s the.

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Some mice may owe their monogamy to a newly evolved type of cell

Science Daily: Pharmacology News

What makes the oldfield mouse steadfastly monogamous throughout its life while its closest rodent relatives are promiscuous? The answer may be a previously unknown hormone-generating cell. Scientists discover the cells and hormones that inspire mice to nurture their young; the same hormones are also present in humans.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Pedal Power: Biking Could Help Prevent Knee Arthritis

Drugs.com

WEDNESDAY, May 15, 2024 -- People who regularly ride bikes throughout their life are less likely to develop knee arthritis, a new study suggests.Bicyclists are 17% less likely to have knee pain and 21% less likely to have symptoms of knee.

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An astrocytic pH regulator that can repair the blood-brain barrier and reverse brain damage caused by ischemic stroke

Science Daily: Pharmacology News

A recent study has found that an ion transporter protein that regulates the pH of specific brain cells can repair the blood-brain barrier and restore normal brain function after ischemic stroke. The study has revealed novel and specific therapeutic targets for ischemic stroke and related brain conditions for which no targeted treatments exist currently.

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Unlocking Undruggable Targets: Shifting Paradigms in Modern Drug Discovery

DrugBank

The road to developing effective drugs is fraught with both promise and challenge, particularly when it comes to what scientists call "undruggable" targets. Let's break down what this means and why it matters to us all. The Evolution of Drug Discovery: From Dark Rooms to Precision Targets In the past, drug discovery often felt like a lucky guess.

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Detection of an Earth-sized exoplanet orbiting the ultracool dwarf star SPECULOOS-3

Science Daily: Pharmacology News

Astronomers have just discovered a new Earth-sized exoplanet around SPECULOOS-3, an 'ultracool dwarf' star as small as Jupiter, twice as cold as our Sun, and located 55 light-years from Earth. After the famous TRAPPIST-1, SPECULOOS 3 is the second planetary system discovered around this type of star.

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Blackstone-backed biotech launches with up to $300M for immune drug

BioPharma Drive: Drug Pricing

Uniquity Bio emerged from stealth mode ready to begin Phase 2 trials of an antibody targeting the protein TSLP in asthma and COPD.

Trials 75
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When saying 'please' is more strategic than magic

Science Daily: Pharmacology News

By kindergarten age, most children have been taught that 'please' is a magic word. 'Please' is an expression of politeness that shows courtesy and respect, turning a potential demand into a request that will -- poof! -- magically be granted. But a new study on the ways people make requests of one another suggests that 'please' might not be an all-purpose marker of politeness, but rather a more focused, strategic tool to manage frictions or obstacles among family members, friends and even coworke

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Bolt Biotherapeutics to lay off staff, abandon lead ADC candidate

BioPharma Drive: Drug Pricing

The company will cut its workforce by half and shuffle leadership as it discontinues testing of the drug trastuzumab imbotolimod.

Drugs 72
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Jet-propelled sea creatures could improve ocean robotics

Science Daily: Pharmacology News

Scientists have discovered that colonies of gelatinous sea animals swim through the ocean in giant corkscrew shapes using coordinated jet propulsion, an unusual kind of locomotion that could inspire new designs for efficient underwater vehicles.

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Novo Holdings buys stake in life sciences tools company; BioMarin lays off 170

BioPharma Drive: Drug Pricing

The parent of Novo Nordisk is acquiring 60% ownership of Single Use Support. Elsewhere, ICER is raising questions about a PTSD drug and BioMarin is cut jobs after a pipeline review.

Science 72
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Next-generation sustainable electronics are doped with air

Science Daily: Pharmacology News

Semiconductors are the foundation of all modern electronics. Now, researchers have developed a new method where organic semiconductors can become more conductive with the help of air as a dopant. The study is a significant step towards future cheap and sustainable organic semiconductors.

Research 122
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Which pharmaceutical drugs have the most drug patents in Mexico?

Drug Patent Watch

This chart shows the drugs with the most patents in Mexico. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.

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Iconic baobabs: The origin and long-distance travels of upside down trees

Science Daily: Pharmacology News

The research cracks the code on the iconic baobab tree's origin story, revealing their surprising origins in Madagascar and incredible long-distance dispersals to Africa and Australia. The study unveils how baobabs developed unique pollination mechanisms -- some attracting hawkmoths, others lemurs, and even bats -- showcasing remarkable evolutionary adaptations.

Research 120
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New patent for Norton Waterford drug QVAR REDIHALER

Drug Patent Watch

Annual Drug Patent Expirations for QVAR+REDIHALER Qvar Redihaler is a drug marketed by Norton Waterford and is included in one NDA. It is available from three suppliers.

Drugs 59
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Join Us for an HPM/Lighthouse Labs Webinar: What the FDA’s Final Rule Means for the Future of Laboratory Developed Tests; Thursday, May 16, 2024: 12:00-1:00 PM EDT

FDA Law Blog: Biosimilars

On April 29, the FDA issued their long-awaited, controversial Final Rule governing the oversight of laboratory developed tests ( LDTs ). This new rule will dramatically alter the LDT regulatory landscape, while at the same time requiring significant operational changes and posing strategic challenges for many LDTs. The final rule also created exemptions for some other LDTs.

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Kickstarting the use of AI for biotechs: part one

Drug Target Review

To calibrate our expectations over the use of AI, the following gives a sobering perspective 1. According to Patrick Malone, a principal at KdT Ventures in the US, clinical wins are rarities in biotech, where an estimated five or 10 percent of drugs that head into human testing actually get approved. 1 “If you take the hype and PR at face value over the last 10 years, you would think it goes from five percent to 90 percent,” Malone said of AI.