Drug Discovery World
MAY 21, 2024
A new study has demonstrated the clinical utility of a machine-learning gene risk score biomarker to predict patient response to Ozempic (semaglutide) and reduce variability. The study ‘Performance of a Machine-Learning Gene Risk Score Biomarker on Predicting Response to Semaglutide’ was led by the Mayo Clinic and presented at Digestive Disease Week 2024.
Science Daily: Pharmacology News
MAY 21, 2024
Researchers have for the first time been able to pin down a prehistoric settlement of early farmers in northern Greece dating back more than 7,000 years to the year. For this they combined annual growth ring measurements on wooden building elements with the sudden spike of cosmogenic radiocarbon in 5259 BC. This provides a reliable chronological reference point for many other archaeological sites in Southeast Europe.
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Drug Discovery World
MAY 21, 2024
The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. From a weight loss drug that prevents heart attacks and a gene therapy that restores hearing, to a vaccine that can treat viruses that don’t exist yet, our chosen news stories this week all represent potential breakthroughs in their respective fields.
Science Daily: Pharmacology News
MAY 21, 2024
Currently available flu medications only target the virus after it has already established an infection, but what if a drug could prevent infection in the first place? Now, scientists have designed drug-like molecules to do just that, by thwarting the first stage of influenza infection.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
MAY 21, 2024
Takara Bio has launched PrimeCap T7 RNA Polymerase (low dsRNA), a mutant T7 RNA polymerase suitable for mRNA therapeutic research and development. PrimeCap T7 RNA Polymerase is a mutant T7 RNA polymerase that has been genetically engineered to maintain high-performance RNA synthesis activity while reducing dsRNA production to less than 10%. Further genetic modifications have resulted in a four-fold reduction of cap analogue concentration in the IVT reaction whilst maintaining a capping efficienc
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- Powerful COVID vaccines could be setting people’s immune systems up to successfully fight off not just future COVID variants, but other types of coronaviruses as well, a new study shows.People repeatedly vaccinated for.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- A quit-smoking drug appears to help people drop their vaping addiction, a new study shows.Vapers who took varenicline (Chantix) were significantly more likely to quit using e-cigarettes loaded with nicotine than those.
Drug Discovery World
MAY 21, 2024
The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. From a weight loss drug that prevents heart attacks and a gene therapy that restores hearing, to a vaccine that can treat viruses that don’t exist yet, our chosen news stories this week all represent potential breakthroughs in their respective fields.
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- Matcha green tea has the potential to keep gum disease at bay, a new study finds.Lab experiments show that matcha can inhibit the growth of Porphyromonas gingivalis, one of the main bacterial culprits behind gum.
Drug Discovery World
MAY 21, 2024
Traditional drug discovery is time-consuming and expensive, and numerous industry studies are showing a year-on-year decrease in return on investment from R&D efforts across the board. Join DDW and FUJIFILM Wako on 24 May 3PM BST to learn more about how AI-AAM (AI-Amino-Acid Mapping), its new proprietary scaffold-hopping method based on AI and chemical simulation techniques, can be used to address this challenge, accelerating the identification of hit compounds and improvements in compound s
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- Fetal exposure to fluoride from a mom-to-be's drinking water might raise the odds for physical and mental health issues in toddlers, new research suggests. The study, which was funded by the U.S. National Institutes of.
Science Daily: Pharmacology News
MAY 21, 2024
Scientists discover 'zoned development' in dinosaur skin, with zones of reptile-style scales and zones of bird-like skin with feathers. A new dinosaur skin fossil has been found to be composed of silica -- the same as glass.
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- Gallbladder cancer rates are steadily increasing among Black Americans, even as they remain stable or decline for most other Americans, a new study warns.Further, growing numbers of cases among Black people are not being.
BioPharma Drive: Drug Pricing
MAY 21, 2024
The U.K. pharma expects to launch 20 new drugs by then, among them complex medicines for cancer as well as treatments for weight loss.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- The legalization of cannabis and the popularity of its edible versions is having an unexpected effect: More seniors landing in emergency departments with overdoses.A new Canadian study found "cannabis poisonings" in the.
Science Daily: Pharmacology News
MAY 21, 2024
A new study suggests better nutrition might help prevent cognitive decline. Working with a group of 100 cognitively healthy participants aged 65 to 75, a research team combined neuroscience with nutritional science to identify a specific nutrient profile linked with better performance on cognitive tests. Nutrient biomarkers identified via blood tests revealed a combination of fatty acids, antioxidants and carotenoids, and two forms of Vitamin E and choline -- very similar to the Mediterranean di
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- Hip replacement is a major, arduous elective surgery, and rehabilitation afterwards takes time, according to an expert from Johns Hopkins Medicine in Baltimore.It'll also take coordinated planning between yourself, your.
Science Daily: Pharmacology News
MAY 21, 2024
Sudden, severe dry spells known as flash droughts are rising in intensity around the world, with a notable exception in mountainous Central Asia, where flash drought extent is shrinking, according to new research. Heat and changes to precipitation patterns caused by a warming climate are driving these trends, the study found.
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- You've watched others shed pounds in a matter of weeks after taking one of the new blockbuster weight-loss drugs, so you decide to try one of the medications yourself, only to discover the needle on your bathroom scale.
BioPharma Drive: Drug Pricing
MAY 21, 2024
Since pivoting from oncology, the startup has raised close to $300 million and advanced an ulcerative colitis drug into mid-stage testing.
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- Giving patients a choice between screening methods could help doctors detect colon cancer earlier, a new study shows.More than double the number of patients underwent colon cancer screening if they were given a choice of.
BioPharma Drive: Drug Pricing
MAY 21, 2024
The U.K. drugmaker aims to catch up in developing new tumor-fighting technologies — areas where it has lagged behind leaders like Novartis and J&J.
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- If you've quit smoking and have switched to vaping instead, your odds for lung cancer won't fall as steeply as if you quit nicotine altogether, new research suggests.“This is the first large population-based study to.
Drug Patent Watch
MAY 21, 2024
Annual Drug Patent Expirations for BELSOMRA Belsomra is a drug marketed by Merck Sharp Dohme and is included in one NDA. It is available from one supplier.
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- Heat waves and heat domes are particularly dangerous to kids with asthma, a new study finds.Daytime heat waves are associated with 19% increased odds that a child with asthma will wind up in the hospital, researchers.
addgene Blog
MAY 21, 2024
If you are job searching, you may be wondering if you need to go to the effort of writing a cover letter. After all, they’re less common than they were ten years ago, and it does take a bit of time to craft one. We still think they're useful, so we've updated our cover letter blog post to help you write the best one possible!
Drugs.com
MAY 21, 2024
TUESDAY, May 21, 2024 -- Many kids can get an occasional upset tummy, but what if your child's stomachaches are more persistent?Dr. David Ziring, associate director of the Pediatric Inflammatory Bowel Disease Program at Cedars-Sinai Guerin.
Science Daily: Pharmacology News
MAY 21, 2024
The analysis of fat traces in over one hundred pottery vessels reveals deep changes in food consumption and preparation by communities living in central Germany between the Early Neolithic and the Late Bronze Age, as well as in their relation with innovations in pottery styles and decorations. In a groundbreaking study, researchers identified a generalized inclusion of dairy products in prehistoric diets, a preference in consuming pork with the arrival of communities from the Eurasian Steppe, an
BioPharma Drive: Drug Pricing
MAY 21, 2024
CEO Cyrus Mozayeni said the company is taking a different approach than other developers of antibody-drug conjugates, though it’s keeping details close.
Science Daily: Pharmacology News
MAY 21, 2024
University of Copenhagen astrophysicists help explain a mysterious phenomenon, whereby stars suddenly vanish from the night sky. Their study of an unusual binary star system has resulted in convincing evidence that massive stars can completely collapse and become black holes without a supernova explosion.
Covalent Modifiers
MAY 21, 2024
Simon C. C. Lucas, J. Henry Blackwell, Ulf Börjesson, David Hargreaves, Alexander G. Milbradt, Samiyah Ahmed, Mark J. Bostock, Carine Guerot, Andrea Gohlke, Olaf Kinzel, Michelle L. Lamb, Nidhal Selmi, Christopher J. Stubbs, Nancy Su, Qibin Su, Haiou Luo, Ting Xiong, Xiaoqian Zuo, Sana Bazzaz, Corey Bienstock, Paolo A. Centrella, Kyle E. Denton, Diana Gikunju, Marie-Aude Guié, John P.
Science Daily: Pharmacology News
MAY 21, 2024
See how an autonomous robot created a shock-absorbing shape no human ever could -- and what it means for designing safer helmets, packaging, car bumpers, and more.
BioPharma Drive: Drug Pricing
MAY 21, 2024
The collaboration, which gives Lilly access to Aktis’ technology in return for $60 million, adds to a flurry of dealmaking in the radiopharma field.
Science Daily: Pharmacology News
MAY 21, 2024
While humans feature a sophisticated sense of smell, insects have a much more basic olfactory system. Yet they depend upon smell to survive. Scientists have figured out how fruit flies use a simple but efficient system to recognize odors, and the answer lies at the edges of their antennae.
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