Wed.Oct 30, 2024

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Large meltwater accumulation revealed inside Greenland Ice Sheet

Science Daily: Pharmacology News

A new study unveils a surprising discovery: a substantial amount of meltwater is temporarily stored within the Greenland Ice Sheet during summer months. For the first time, an international group of researchers was able to quantify meltwater with positioning data. The finding challenges current models of how ice sheets contribute to global sea level rise.

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Researchers map communities of single cells in metastatic breast cancers

Broad Institute

Researchers map communities of single cells in metastatic breast cancers By Corie Lok October 30, 2024 Breadcrumb Home Researchers map communities of single cells in metastatic breast cancers The team compared different single-cell and spatial profiling methods to explore the diversity of cells in metastatic breast cancer biopsies. By Sarah C.P. Williams October 30, 2024 Credit: Cecil Fox, National Cancer Institute, National Institutes of Health Human breast cancer tissue with cancer cells (purp

Research 127
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It's not to be. Universe too short for Shakespeare typing monkeys

Science Daily: Pharmacology News

It would take far longer than the lifespan of our universe for a typing monkey to randomly produce Shakespeare, a new study reveals.

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Organoids: the versatile platform for discovery and regeneration

Drug Target Review

Imagine being able to create an in vitro replica of a diseased organ to study the molecular mechanism underlying the illness. Now take a step further: envision testing drugs in these organoids to identify the ones that can treat disease safely and effectively without needing to run expensive clinical trials first. Further still, think about implanting these mini organs into the patient to restore lost function.

Treatment 105
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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One of the fastest-spinning stars in the Universe

Science Daily: Pharmacology News

New research in our Milky Way has revealed a neutron star that rotates around its axis at an extremely high speed. It spins 716 times per second, making it one of the fastest-spinning objects ever observed.

Research 330

More Trending

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Low-level lead poisoning is still pervasive in the US and globally

Science Daily: Pharmacology News

Chronic, low-level lead poisoning is a major risk factor for cardiovascular disease in adults and cognitive deficits in children, even at levels previously thought to be safe, Low-level lead poisoning is a risk factor for preterm. Annually 5.5 million deaths from cardiovascular disease attributed to low-level lead poisoning; accounts for a loss of 765 million IQ points in children.

Disease 328
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Biogen, Sage admit a defeat in major depression

BioPharma Drive: Drug Pricing

The partners no longer intend to develop Zurzuvae for one of the most common forms of depression, citing the time and cost of running new studies that would satisfy the FDA.

FDA 280
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'Black box' of stem cell transplants opened in blood study

Science Daily: Pharmacology News

New research into the long-term dynamics of transplanted stem cells in a patient's body explains how age affects stem cell survival and immune diversity, offering insights that could make transplants safer and more successful.

Research 299
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Once Again, Tuberculosis Becomes World's Top Infectious Disease Killer

Drugs.com

WEDNESDAY, Oct. 30, 2024 -- In the highest tally ever recorded for tuberculosis cases, the World Health Organization reported Tuesday that over 8 million people worldwide were diagnosed with the lung disease last year.Of that number, 1.25 million.

Disease 279
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Farewell frost! New surface prevents frost without heat

Science Daily: Pharmacology News

In a new study, researchers discovered that tweaking the texture of any surface and adding a thin layer of graphene oxide prevents 100% of frost from forming on surfaces for one week or potentially even longer. This is 1,000 times longer than current, state-of-the-art anti-frosting surfaces.

Research 296
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Lilly shares fall as obesity drug sales miss forecasts

BioPharma Drive: Drug Pricing

Third quarter Mounjaro and Zepbound sales, while up substantially versus the same period last year, grew little compared to the second quarter amid inventory decreases in the U.S.

Drugs 278
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A rudimentary quantum network link between Dutch cities

Science Daily: Pharmacology News

Researchers have demonstrated a network connection between quantum processors over metropolitan distances. Their result marks a key advance from early research networks in the lab towards a future quantum internet. The team developed fully independently operating nodes and integrated these with deployed optical internet fiber, enabling a 25-km quantum link.

Research 294
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GSK vaccine sales sink on lower demand for RSV, shingles shots

BioPharma Drive: Drug Pricing

The British pharma’s experience during the third quarter mirrored that of rival Pfizer, which also reported lower sales of its competing RSV shot.

Vaccine 273
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Alcohol consumption among non-human animals may not be as rare as previously thought, say ecologists

Science Daily: Pharmacology News

Anecdotes abound of wildlife behaving 'drunk' after eating fermented fruits, but despite this, nonhuman consumption of ethanol has been assumed to be rare and accidental. Ecologists now challenge this assumption. They argue that since ethanol is naturally present in nearly every ecosystem, it is likely consumed on a regular basis by most fruit- and nectar-eating animals.

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Novo takes big step toward ending Ozempic, Wegovy shortages

BioPharma Drive: Drug Pricing

All doses of the two drugs are now listed as available in the U.S., per an FDA database, although the company cautioned patients may still experience "variability" filling their prescriptions.

FDA 265
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Combining VR and non-invasive brain stimulation: A neurotechnology that boosts spatial memory without surgery

Science Daily: Pharmacology News

Researchers have joined forces to give a boost to spatial memory by creating a unique experimental setup that combines non-invasive deep-brain stimulation, virtual reality training, and fMRI imaging. The study demonstrates that targeted, painless electric impulses to the hippocampus and adjacent structures, a deep brain region implied in memory and spatial navigation, can improve the brain's ability to recall locations and navigate more effectively.

Research 269
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What You Don't Know About Pancreatic Cancer Could Harm You

Drugs.com

WEDNESDAY, Oct. 30, 2024 -- Pancreatic cancer rates are rising in adults younger than 50, but many continue to believe it’s a disease that only affects the elderly, a new survey shows.Folks in that age range also say they wouldn’t be able to ide.

Disease 264
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Handling Drug Patent Abandonment: Opportunities and Challenges

Drug Patent Watch

The pharmaceutical industry is known for its complex regulatory environment and lengthy product development processes. One often overlooked aspect of this industry is the potential benefits of abandoned and expired patents. These patents can provide opportunities for companies to bring new products to market at a lower cost and with reduced development time.

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Autism Diagnoses Rising Among U.S. Children, Adults

Drugs.com

WEDNESDAY, Oct. 30, 2024 -- Big surges in new autism diagnoses among young adults, as well a rise in diagnoses for girls and young women, have driven a near-tripling of U.S. autism cases in just over a decade, researchers report. Data on over 12.

Research 264
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High Throughput AI-Driven Drug Discovery Pipeline

Nvidia Developer: Drug Discovery

The integration of AI in drug discovery is revolutionizing the way researchers approach the development of new treatments for various diseases. Traditional. The integration of AI in drug discovery is revolutionizing the way researchers approach the development of new treatments for various diseases. Traditional methods are often time-consuming and costly, with the process of bringing a new drug to market taking up to 15 years and costing between $1–2B.

Drugs 87
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Lack of Insurance Could Mean Later Cancer Diagnoses for Black, Hispanic Americans

Drugs.com

WEDNESDAY, Oct. 30, 2024 -- A lack of health insurance coverage raises the risk that cancers among Black and Hispanic Americans will be caught too late, a new study suggests. Being uninsured accounts for a significant proportion of racial and.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Product Highlight: DrugBank on Snowflake Marketplace

DrugBank

At DrugBank, we’re dedicated to empowering pharmaceutical researchers with data that drives impactful results. Now, through our partnership with Snowflake, we’re making it even easier than ever for you to access high-quality, actionable data in a secure, and scalable environment designed to keep pace with your research needs. With this integration, we’re focused on enhancing your ability to access the data you need, when you need it.

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Half of U.S. Teens Stare at Screens More Than 4 Hours Per Day

Drugs.com

WEDNESDAY, Oct. 30, 2024 -- Half of young Americans between the ages of 12 and 17 spend at least four hours each day on their smartphones, computers or televisions, a new survey shows."As technology has become more integrated into teenagers’ lives.

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Investors put $115M into Axonis amid revived interest in brain drugs

BioPharma Drive: Drug Pricing

The funding for Axonis, which is developing novel medicines for pain and epilepsy, reflects growing confidence in precision therapies for neurological diseases, one investor told BioPharma Dive.

Therapies 171
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1 in 3 U.S. Teens Say They've Been Bullied

Drugs.com

WEDNESDAY, Oct. 30, 2024 -- Bullying among American teens remains a big threat, with more than a third (34%) saying they've been bullied over the past year, new government data shows. According to the report's authors, bullying occurs when a person.

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Biogen optimistic as new products gain traction

BioPharma Drive: Drug Pricing

Even though Biogen raised earnings guidance, the company still has “some potentially concerning signals” in its base business, according to one analyst.