Broad Institute

OCTOBER 30, 2024

Researchers map communities of single cells in metastatic breast cancers By Corie Lok October 30, 2024 Breadcrumb Home Researchers map communities of single cells in metastatic breast cancers The team compared different single-cell and spatial profiling methods to explore the diversity of cells in metastatic breast cancer biopsies. By Sarah C.P. Williams October 30, 2024 Credit: Cecil Fox, National Cancer Institute, National Institutes of Health Human breast cancer tissue with cancer cells (purp

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Research RNA Medical Schools Treatment 127

Nvidia Developer: Drug Discovery

OCTOBER 30, 2024

The integration of AI in drug discovery is revolutionizing the way researchers approach the development of new treatments for various diseases. Traditional. The integration of AI in drug discovery is revolutionizing the way researchers approach the development of new treatments for various diseases. Traditional methods are often time-consuming and costly, with the process of bringing a new drug to market taking up to 15 years and costing between $1–2B.

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Drugs Treatment Disease Research 126

BioPharma Drive: Drug Pricing

OCTOBER 30, 2024

Third quarter Mounjaro and Zepbound sales, while up substantially versus the same period last year, grew little compared to the second quarter amid inventory decreases in the U.S.

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Drugs 118

Science Daily: Pharmacology News

OCTOBER 30, 2024

A new study unveils a surprising discovery: a substantial amount of meltwater is temporarily stored within the Greenland Ice Sheet during summer months. For the first time, an international group of researchers was able to quantify meltwater with positioning data. The finding challenges current models of how ice sheets contribute to global sea level rise.

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International Research 122

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

BioPharma Drive: Drug Pricing

OCTOBER 30, 2024

The partners no longer intend to develop Zurzuvae for one of the most common forms of depression, citing the time and cost of running new studies that would satisfy the FDA.

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FDA 119

Science Daily: Pharmacology News

OCTOBER 30, 2024

New research in our Milky Way has revealed a neutron star that rotates around its axis at an extremely high speed. It spins 716 times per second, making it one of the fastest-spinning objects ever observed.

Research 120

Research 120

Science Daily: Pharmacology News

OCTOBER 30, 2024

A new study finds that up to 215 million hectares of land (an area larger than Mexico) in humid tropical regions around the world has the potential to naturally regrow. That much forest could store 23.4 gigatons of carbon over 30 years and also have a significant impact on concerns like biodiversity loss and water quality. The study showed that more than half of the area with strong potential for regrowth was in five countries: Brazil, Mexico, Indonesia, China, and Colombia.

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BioPharma Drive: Drug Pricing

OCTOBER 30, 2024

Archon Biosciences, co-founded by the winner of the 2024 Nobel Prize in Chemistry, emerged from stealth Wednesday with $20 million in seed capital.

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Science Daily: Pharmacology News

OCTOBER 30, 2024

It would take far longer than the lifespan of our universe for a typing monkey to randomly produce Shakespeare, a new study reveals.

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Fierce BioTech

OCTOBER 30, 2024

| While artificial intelligence is on everyone’s minds and in many R&D plans, adoption of generative AI has been slow so far in life sciences.

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Science 118

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Science Daily: Pharmacology News

OCTOBER 30, 2024

Chronic, low-level lead poisoning is a major risk factor for cardiovascular disease in adults and cognitive deficits in children, even at levels previously thought to be safe, Low-level lead poisoning is a risk factor for preterm. Annually 5.5 million deaths from cardiovascular disease attributed to low-level lead poisoning; accounts for a loss of 765 million IQ points in children.

Disease 117

Disease 117

Drug Target Review

OCTOBER 30, 2024

Imagine being able to create an in vitro replica of a diseased organ to study the molecular mechanism underlying the illness. Now take a step further: envision testing drugs in these organoids to identify the ones that can treat disease safely and effectively without needing to run expensive clinical trials first. Further still, think about implanting these mini organs into the patient to restore lost function.

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Treatment Disease Clinical Trials Molecular Biology 105

Science Daily: Pharmacology News

OCTOBER 30, 2024

A new study sheds light on how the blood-borne parasite that causes African sleeping sickness in humans and related diseases in cattle and other animals establishes long-term infections in hosts. Using a mouse model, the researchers showed that Trypanosoma brucei essentially plays a game of hide-and-seek by setting up shop in its hosts' tissues, allowing it to constantly change its protective surface coat and evade antibodies.

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Immune Response Disease Research 114

Drugs.com

OCTOBER 30, 2024

WEDNESDAY, Oct. 30, 2024 -- In the highest tally ever recorded for tuberculosis cases, the World Health Organization reported Tuesday that over 8 million people worldwide were diagnosed with the lung disease last year.Of that number, 1.25 million.

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Disease 111

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

BioPharma Drive: Drug Pricing

OCTOBER 30, 2024

The British pharma’s experience during the third quarter mirrored that of rival Pfizer, which also reported lower sales of its competing RSV shot.

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Vaccine 116

Drugs.com

OCTOBER 30, 2024

WEDNESDAY, Oct. 30, 2024 -- Pancreatic cancer rates are rising in adults younger than 50, but many continue to believe it’s a disease that only affects the elderly, a new survey shows.Folks in that age range also say they wouldn’t be able to ide.

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Disease 105

Science Daily: Pharmacology News

OCTOBER 30, 2024

In a new study, researchers discovered that tweaking the texture of any surface and adding a thin layer of graphene oxide prevents 100% of frost from forming on surfaces for one week or potentially even longer. This is 1,000 times longer than current, state-of-the-art anti-frosting surfaces.

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Research 102

Drugs.com

OCTOBER 30, 2024

WEDNESDAY, Oct. 30, 2024 -- Big surges in new autism diagnoses among young adults, as well a rise in diagnoses for girls and young women, have driven a near-tripling of U.S. autism cases in just over a decade, researchers report. Data on over 12.

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Research 105

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

OCTOBER 30, 2024

Researchers have joined forces to give a boost to spatial memory by creating a unique experimental setup that combines non-invasive deep-brain stimulation, virtual reality training, and fMRI imaging. The study demonstrates that targeted, painless electric impulses to the hippocampus and adjacent structures, a deep brain region implied in memory and spatial navigation, can improve the brain's ability to recall locations and navigate more effectively.

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Research 97

Drug Patent Watch

OCTOBER 30, 2024

The pharmaceutical industry is known for its complex regulatory environment and lengthy product development processes. One often overlooked aspect of this industry is the potential benefits of abandoned and expired patents. These patents can provide opportunities for companies to bring new products to market at a lower cost and with reduced development time.

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Pharmaceuticals Production Drugs Marketing 80

Science Daily: Pharmacology News

OCTOBER 30, 2024

Researchers have demonstrated a network connection between quantum processors over metropolitan distances. Their result marks a key advance from early research networks in the lab towards a future quantum internet. The team developed fully independently operating nodes and integrated these with deployed optical internet fiber, enabling a 25-km quantum link.

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Research 95

DrugBank

OCTOBER 30, 2024

At DrugBank, we’re dedicated to empowering pharmaceutical researchers with data that drives impactful results. Now, through our partnership with Snowflake, we’re making it even easier than ever for you to access high-quality, actionable data in a secure, and scalable environment designed to keep pace with your research needs. With this integration, we’re focused on enhancing your ability to access the data you need, when you need it.

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Production Clinical Trials Packaging Compliance 75

Science Daily: Pharmacology News

OCTOBER 30, 2024

Geneticists have deciphered the prehistory of aurochs -- the animals that were the focus of some of the most iconic early human art -- by analyzing 38 genomes harvested from bones dating across 50 millennia and stretching from Siberia to Britain. The aurochs roamed in Europe, Asia and Africa for hundreds of thousands of years. Adorned as paintings on many a cave wall, their domestication to create cattle gave us a harnessed source of muscle, meat and milk.

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DNA 93

BioPharma Drive: Drug Pricing

OCTOBER 30, 2024

The funding for Axonis, which is developing novel medicines for pain and epilepsy, reflects growing confidence in precision therapies for neurological diseases, one investor told BioPharma Dive.

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Therapies Disease Drugs 75

Science Daily: Pharmacology News

OCTOBER 30, 2024

New research into the long-term dynamics of transplanted stem cells in a patient's body explains how age affects stem cell survival and immune diversity, offering insights that could make transplants safer and more successful.

Research 90

Research 90

Drugs.com

OCTOBER 30, 2024

WEDNESDAY, Oct. 30, 2024 -- Bullying among American teens remains a big threat, with more than a third (34%) saying they've been bullied over the past year, new government data shows. According to the report's authors, bullying occurs when a person.

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Government 95

Science Daily: Pharmacology News

OCTOBER 30, 2024

Anecdotes abound of wildlife behaving 'drunk' after eating fermented fruits, but despite this, nonhuman consumption of ethanol has been assumed to be rare and accidental. Ecologists now challenge this assumption. They argue that since ethanol is naturally present in nearly every ecosystem, it is likely consumed on a regular basis by most fruit- and nectar-eating animals.

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Drugs.com

OCTOBER 30, 2024

WEDNESDAY, Oct. 30, 2024 -- Half of young Americans between the ages of 12 and 17 spend at least four hours each day on their smartphones, computers or televisions, a new survey shows."As technology has become more integrated into teenagers’ lives.

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Science Daily: Pharmacology News

OCTOBER 30, 2024

Energy-making chloroplasts from algae have been inserted into hamster cells, enabling the cells to photosynthesize light, according to new research in Japan. It was previously thought that combining chloroplasts (chlorophyll containing structures in the cells of plants and algae) with animal cells was not possible, and that the chloroplasts would not survive or function.

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Engineering Research 76

Drugs.com

OCTOBER 30, 2024

WEDNESDAY, Oct. 30, 2024 -- A lack of health insurance coverage raises the risk that cancers among Black and Hispanic Americans will be caught too late, a new study suggests. Being uninsured accounts for a significant proportion of racial and.

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BioPharma Drive: Drug Pricing

OCTOBER 30, 2024

Even though Biogen raised earnings guidance, the company still has “some potentially concerning signals” in its base business, according to one analyst.

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Production 69

Perficient: Drug Development

OCTOBER 30, 2024

This is not a rant, but rather a learning, there are thousands of ways to do something wrong, very few to do it right. I must say, I have been a part of few that went wrong for sure and hence this blog. In the early and dreamy years of my career, I was once part of a project team that decided to “go Agile” because, hey, it’s the new millennium, and you know, it’s trendy, and everyone’s doing it.

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Production 52

Fierce BioTech

OCTOBER 30, 2024

Optimizing Imaging Response Criteria for Improved Outcomes in Oncology Clinical Trials Enhance clinical trial outcomes by customizing radiologic assessment criteria with expert insights. This whitepaper covers the limitations of standard criteria like RECIST, Lugano, and RANO and shows how tailored imaging solutions can clarify ambiguities, optimize assessments, and adapt to new oncology therapies, driving higher success rates in regulatory approvals. dfarris Wed, 10/30/2024 - 15:03 Enhance clin

Clinical Trials 52

Clinical Trials Trials Therapies Research 52