BioPharma Drive: Drug Pricing
JUNE 7, 2024
A vote against MDMA-assisted therapy set back a high-profile treatment. Proponents argue the panel offered few solutions to longstanding problems, making the path forward unclear.
ASPET
JUNE 7, 2024
While acute inflammation serves essential functions in maintaining tissue homeostasis, chronic inflammation is causally linked to many diseases. Macrophages are a major cell-type that orchestrates inflammatory processes. During inflammation, macrophages undergo polarization and activation, thereby mobilizing pro-inflammatory and anti-inflammatory transcriptional programs that regulate ensuing macrophage functions.
Drugs.com
JUNE 7, 2024
FRIDAY, June 7, 2024 -- Roughly 1 in 6 people who stop taking an antidepressant will experience symptoms caused by discontinuing the drug, a new review finds.However, only 1 in 35 will experience severe symptoms after dropping their medication.
ASPET
JUNE 7, 2024
Beta-adrenergic receptors (β-AR) are expressed on the membranes of various cell types and their activation affects body water balance by modulating renal sodium and water excretion, cardiovascular function and metabolic processes. However, β-AR-associated body fluid imbalance has not been well characterised. In the present study, we hypothesized that chronic β-AR stimulation increases electrolyte and water content at the tissue level.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
JUNE 7, 2024
FRIDAY, June 7, 2024 -- A ban on Juul e-cigarettes has been reversed, the U.S. Food and Drug Administration announced Thursday.Why? The agency said it needs to review both new court decisions and updated data from the vape maker. While the.
ASPET
JUNE 7, 2024
Triple-negative breast cancer (TNBC) is characterized by high mortality rates primarily due to its propensity for metastasis. Addressing this challenge necessitates the development of effective antimetastatic therapies. This study aimed to identify natural compounds with potential antimetastatic properties mainly based on the high-throughput phenotypic screening system.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Reprocell
JUNE 7, 2024
In his opening remarks during a welcome reception at the 27 th annual meeting of the American Society of Gene & Cell Therapy , Maryland Secretary of Commerce Kevin Anderson touted the most recent accomplishments of biotech companies including Regenexbio, MaxCyte, and AstraZeneca. What these companies have in common is that they are all in the heart of Maryland’s biotech corridor in Montgomery County and their successes contribute to Maryland’s mission to make the state a biotech hub.
Drugs.com
JUNE 7, 2024
FRIDAY, June 7, 2024 -- Severe forms of autism could be linked to overgrowth of the brain’s outer layer that starts while a baby is in the womb, a new study finds.Toddlers with autism have cerebral cortexes -- often referred to as “gray matter” -- t.
Science Daily: Pharmacology News
JUNE 7, 2024
Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, this study, is an unbiased gene-editing approach to increase gene expression and downstream photosynthetic activity. The approach is more difficult than transgenic breeding, but could potentially preempt regulatory issues by changing DNA already within the plant, allowing the plants to get in the ha
Drugs.com
JUNE 7, 2024
FRIDAY, June 7, 2024 -- New research shows that a set of healthy lifestyle habits can help preserve brain function in folks with mild cognitive impairment or early dementia.About 71% of patients who ate healthy, exercised regularly and engaged in.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Science Daily: Pharmacology News
JUNE 7, 2024
Ancient apes in Germany co-existed by partitioning resources in their environment, according to a new study.
Drugs.com
JUNE 7, 2024
FRIDAY, June 7, 2024 -- Anthrax disease in humans is rare and when it does occur, it's usually during hot, dry summers.That's why the case of a Texas rancher who developed anthrax in January of this year piqued the interest of investigators at the.
Drug Target Review
JUNE 7, 2024
How does Immunocore’s TCR technology differentiate itself from other approaches to targeted cancer therapy? Our proprietary ImmTAC (Immune Mobilizing Monoclonal TCRs Against Cancer) technology is comprised of a bispecific molecule where the effector end (anti-CD3) is designed to specifically activate the immune system (ie, T cells) against tumour cells to destroy them.
Drugs.com
JUNE 7, 2024
FRIDAY, June 7, 2024 -- Vigorous exercise more than once a week can lower the risk of dementia for people with high blood pressure, a new clinical trial shows.People who engaged each week in vigorous physical activity had lower rates of mild.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
BioPharma Drive: Drug Pricing
JUNE 7, 2024
After 34 years, Geron finally has an approved medicine in Rytelo. Elsewhere, Shionogi disclosed disappointing obesity drug data and AbbVie got some good trial news.
Drugs.com
JUNE 7, 2024
FRIDAY, June 7, 2024 -- An extended course of the antiviral drug Paxlovid won’t ease a person’s Long COVID symptoms, a new study finds. People who took Paxlovid for 15 days -- three times as long as it’s prescribed for an initial.
Agency IQ
JUNE 7, 2024
BY CHELSEY MCINTYRE, PHARMD Since the passage of the Dietary Supplement Health and Education Act (DSHEA) 30 years ago, the U.S. dietary supplement market has grown into a vast industry that has little in common with its DSHEA-era predecessor. Over the years, the retroactive structure of DSHEA has encouraged the influx of bad actors who have identified the dietary supplement sector as a venue for the introduction of unapproved drugs into the U.S. market.
Drugs.com
JUNE 7, 2024
FRIDAY, June 7, 2024 -- If your child is among the youngest in their school grade, it's more likely they'll be mistakenly identified by teachers as having ADHD or autism, a new study confirms."Adults involved in identifying or raising concerns over.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Agency IQ
JUNE 7, 2024
BY WALKER LIVINGSTON, ESQ The Environmental Protection Agency (EPA) has proposed a suite of actions for n-methylpyrrolidone (NMP), including capping concentrations at 45% and implementing a series of bans for consumer, commercial, and industrial uses. Under the Toxic Substances Control Act (TSCA), the EPA is required to conduct risk evaluations of chemicals.
Cytel
JUNE 7, 2024
In this latest edition of the Career Perspectives series, we are excited to introduce our readers to Karl Karu, Senior Statistical Programmer in Functional Service Provider (FSP) at Cytel. Karl is based in Estonia and joined Cytel in September 2023. Join us as we delve into his refreshing and enthusiastic perspective on statistical programming and the skills it requires, the importance of communication with sponsors, and a work-life balance when working from home.
Agency IQ
JUNE 7, 2024
BY LAURA DIANGELO, MPH Under the FDA’s Bioresearch Monitoring (BIMO) program, the agency oversees the operation of regulated research. After a Congressional directive, the agency has now released new draft guidance on the processes and practices on BIMO inspections. The new draft guidance comes as there is a major overhaul of the Office of Regulatory Affairs (ORA) in the works, and new authorities on Remote Regulatory Assessments (RRAs) are being implemented.
Quanticate
JUNE 7, 2024
Discover how Risk-Based Quality Management (RBQM) optimizes clinical data management for improved safety, efficiency, and regulatory compliance in clinical trials
Agency IQ
JUNE 7, 2024
BY COREY JASEPH, MS, RAC While the European Commission has been laser-focused on the number of medical device and IVD certificates, AgencyIQ is taking a look at progress toward designating Notified Bodies to the European medical device and diagnostics regulations. While designation numbers are up, there are still concerns that manufacturers need to be aware of.
Common Sense for Drug Policy Blog
JUNE 7, 2024
Community Pharmacies and Harm Reduction "Community pharmacies are essential healthcare destinations that serve as an optimal resource for addressing non-urgent inquiries, such as safe injecting practices, management of adverse drug reactions, and medication provision, thus reducing the burden on general practitioners (GPs) [ 1 , 2 ]. Pharmacists also have a role in addressing social determinants of health and promoting health equity, including the support of primary prevention strategies such as
Agency IQ
JUNE 7, 2024
BY SCOTT STEPHENS, MPA The Commission has issued uniform rules governing data requirements and a work program for safeners and synergists, constituent compounds that, like active substances, must be approved for use in plant protection products in the EU. Almost 10 years late, the new framework’s arrival will represent significant changes in the regulation of these pesticide substances.
Common Sense for Drug Policy Blog
JUNE 7, 2024
Community Pharmacies and Anabolic-Androgenic Steroid Consumers "With the growing availability of AAS [Anabolic-Androgenic Steroids] through online platforms [ 71 , 72 ] the traditional reliance on social networks and healthcare providers for access to injecting equipment and safer use information has diminished [ 73 – 76 ]. This unregulated supply of AAS and other PIEDs from online sources is accompanied by misleading information regarding the benefits and risks associated with their use [ 13 ,
Antidote
JUNE 7, 2024
Recruiting and retaining patients are two of the most challenging aspects of clinical trials. The average clinical trial must extend its recruitment timeline by 71%, and up to 30% of patients will eventually drop out. While patients can leave a trial if it is not a good fit for them, there are patient-centric approaches that can make enrolling and participating in a study a more enjoyable experience.
Drug Channels
JUNE 7, 2024
Today’s guest post comes from Nasir Ali, Chief Product Officer at CareMetx. Nasir highlights manufacturers' top objectives and vendor metrics from CareMetx’s recent survey of leaders and decision makers in the specialty pharmaceutical industry. He then outlines key questions to help manufacturers evaluate their potential hub partners. You can donwload CareMetx’s full 2024 Patient Services Report here: Revealing Manufacturer Priorities: Patients Naturally Take Center Stage.
Drug Patent Watch
JUNE 7, 2024
Annual Drug Patent Expirations for ILEVRO Ilevro is a drug marketed by Harrow Eye and is included in one NDA. It is available from two suppliers.
Reprocell
JUNE 7, 2024
Discover how functional genomics is transforming IBD treatment with groundbreaking research on ETS2's role in inflammation.
Drug Patent Watch
JUNE 7, 2024
This chart shows the pharmaceutical companies with the most supplementary protection certificates (SPCs) in Norway.
Agency IQ
JUNE 7, 2024
The FDA tried to call the dietary supplement industry’s bluff. It appears to have blinked. Since the passage of the Dietary Supplement Health and Education Act (DSHEA) 30 years ago, the U.S. dietary supplement market has grown into a vast industry that has little in common with its DSHEA-era predecessor. Over the years, the retroactive structure of DSHEA has encouraged the influx of bad actors who have identified the dietary supplement sector as a venue for the introduction of unapproved drugs i
Alta Sciences
JUNE 7, 2024
Locations_on_map_Clinical ehdem Fri, 06/07/2024 - 15:38 Image Locations_on_map_Clinical.
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