Tue.Nov 26, 2024

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Delay and pay: Climate tipping point costs quadruple after waiting

Science Daily: Pharmacology News

The cost of reversing the effects of climate change -- restoring melted polar sea ice, for example -- quickly climbs nearly fourfold soon after a tipping point is crossed, according to new work. Much work has been done to explore the environmental costs tied to climate change. But this new study marks the first time researchers have quantified the costs of controlling tipping points before and after they unfold.

Research 117
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Biden Will Move to Have Medicare, Medicaid Cover GLP-1 Weight-Loss Meds, such as Wegovy, Zepbound

Drugs.com

TUESDAY, Nov. 26, 2024 -- The outgoing Biden administration will propose that pricey GLP-1 obesity medications such as semaglutide (Wegovy), and tirzepatide (Zepbound) be covered by Medicare and Medicaid. However, the move would have to be approved.

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Brain test shows that crabs process pain

Science Daily: Pharmacology News

Researchers have demonstrated that painful stimuli are sent to the brain of shore crabs providing more evidence for pain in crustaceans. EEG style measurements show clear neural reactions in the crustacean's brain during mechanical or chemical stimulation.

Research 105
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Intellectual Property Rights and Regulatory Considerations for Drug Repurposing

Drug Patent Watch

In the ever-evolving landscape of pharmaceutical research and development, drug repurposing has emerged as a promising strategy to bring new treatments to patients more quickly and cost-effectively. However, navigating the complex web of intellectual property rights and regulatory considerations in this field can be challenging.

Drugs 94
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Unexplained heat-wave 'hotspots' are popping up across the globe

Science Daily: Pharmacology News

A striking new phenomenon is emerging: distinct regions are seeing repeated heat waves that are so extreme, they fall far beyond what any model of global warming can predict or explain. A new study provides the first worldwide map of such regions, which show up on every continent except Antarctica like giant, angry skin blotches.

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Biden Will Move to Have Medicare, Medicaid Cover GLP-1 Weight-Loss Meds

Drugs.com

TUESDAY, Nov. 26, 2024 -- The outgoing Biden administration will propose that pricey GLP-1 obesity medications such as semaglutide (Wegovy), and tirzepatide (Zepbound) be covered by Medicare and Medicaid.However, the move would have to be approved.

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Twelve Amazing Guest Blog Contributors!

addgene Blog

It’s a very thankful time of year for those of us at Addgene! And we can’t think of any better way to start off our holiday season than by thanking the twelve guest bloggers and subject matter experts who have contributed to our blog in 2024.

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Magnetic tornado is stirring up the haze at Jupiter's poles

Science Daily: Pharmacology News

Dark ovals in Jupiter's polar haze, visible only at UV wavelengths, were first noticed 25 years ago, then ignored. A new study shows that these dark UV ovals are common, appearing at the south pole in 75% of Hubble Space Telescope images taken since 2015. They appear less often at the north pole. The scientists theorize that a magnetic vortex generated in the ionosphere stirs up and concentrates the hydrocarbon haze that blankets the poles.

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Alector turns to layoffs as Alzheimer’s drug fails

BioPharma Drive: Drug Pricing

The brain drug developer is letting go of around 41 of its 238 employees, in a move the company says will help “align resources” with its strategic priorities.

Drugs 62
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Study Finds GLP-1 Meds, such as Ozempic, Wegovy, Can Also Help the Kidneys

Drugs.com

TUESDAY, Nov. 26, 2024 -- The potential health benefits of GLP-1 diabetes and weight loss meds keep piling up: New research shows they may also shield your kidneys from harm. In the largest study to date on the effects of the drugs on the kidneys.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Roche to buy cell therapy developer Poseida for $1B

BioPharma Drive: Drug Pricing

The deal suggests Roche sees substantial promise in Poseida’s technology, as the offer is 215% above the biotech’s closing share price on Monday.

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There's a Best Option for Patients With Head-and-Neck Cancer Who Can't Take Cisplatin

Drugs.com

TUESDAY, Nov. 26, 2024 -- Cisplatin is the go-to chemotherapy for people battling head-and-neck cancers, but nearly a third of patients can't tolerate its side effects and quit the drug.A new trial offers surprising results on the best second-line.

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Amgen obesity drug cuts weight in study, but results miss Wall Street’s high mark

BioPharma Drive: Drug Pricing

Shares in Amgen fell by double digits Tuesday on results for the company’s MariTide shot, which is viewed as a potential rival to Wegovy and Zepbound.

Drugs 62
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The NIOSH Respirator Fit Evaluation Challenge

NIOSH Science Blog: Drugs

Millions of workers across the United States rely on tight-fitting respirators to keep them safe on the job. These workers have a wide variability in facial features and dimensions, making it challenging to identify specific respirator models and sizes that will provide a proper fit. If a respirator does not properly fit, forming a tight seal against the wearer’s face, then it may not provide the expected level of protection.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Roche’s TIGIT-targeting drug for cancer fails its biggest test

BioPharma Drive: Drug Pricing

Long-awaited results released Tuesday showed adding tiragolumab to Roche's immunotherapy Tecentriq did not extend survival in a closely followed Phase 3 study called SKYSCRAPER-01.

Drugs 57
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ADA Compliance – Frontend Developer’s Guide

Perficient: Drug Development

Why ADA Compliance matters in web development Making web content accessible to everyone is not just a requirement – it’s a commitment. ADA Compliance in front-end development ensures websites are navigable and usable for all, including people with disabilities. This enhances user experiences, boosts search engine optimization (SEO), and protects against accessibility-related legal issues.

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Gentlemen, Start Your Engines: DEA’s Marijuana Rescheduling Hearing Begins Monday

FDA Law Blog: Biosimilars

By Larry K. Houck — Last May the Department of Justice (“DOJ”) and the Drug Enforcement Administration (“DEA”) issued a Notice of Proposed Rulemaking (“NPRM”) to transfer marijuana from schedule I of the Controlled Substances Act (“CSA”) to schedule III. Schedules of Controlled Substances: Rescheduling of Marijuana, 89 Fed. Reg. 44,597 (May 21, 2024).

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Universal Design for Cognitive Disabilities in Healthcare –Simplifying Medical Terminology – 7

Perficient: Drug Development

Medical jargon can often be complex and confusing, creating barriers to understanding for patients with cognitive disabilities. Simplifying medical terminology ensures that healthcare information is accessible, clear, and easy to comprehend. Here’s how to effectively simplify medical language: The Importance of Simplifying Medical Terminology Simplifying medical terminology helps patients with cognitive disabilities understand their health conditions, treatment options, and care instructions.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Beyond Data Collection: How Modern EDC Systems Are Becoming Clinical Intelligence Hubs

Crucial Data Solutions

For years, electronic data capture (EDC) systems have been the backbone of clinical trials, efficiently collecting and managing study data. The post Beyond Data Collection: How Modern EDC Systems Are Becoming Clinical Intelligence Hubs appeared first on Crucial Data Solutions.

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Universal Design for Cognitive Disabilities in Healthcare –Utilizing Diagrams and Charts – 8

Perficient: Drug Development

Visual aids like diagrams and charts play a crucial role in making healthcare information more accessible and comprehensible. They provide a visual representation of complex concepts, helping patients with cognitive disabilities better understand their health conditions and treatments. Here’s how healthcare providers can effectively use diagrams and charts: The Importance of Diagrams and Charts Diagrams and charts simplify complex information, making it easier for patients to visualize and grasp

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"Pink Cocaine", Otherwise Known As Tusi

Common Sense for Drug Policy Blog

"Pink Cocaine", Otherwise Known As Tusi "The tusi phenomenon complicates the drug landscape because it has the potential to confuse both people who use and researchers alike. With respect to people who use, given the drug concoction’s name, people may assume the drug is 2C/2C-B. Since many partiers are unfamiliar with 2C series drugs ( 14 ), there is also potential for people to simply think this is a new (and perhaps benign) drug – especially given that the powder is pink with a sweet scent.

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Frequently Asked Questions about L2C

Broad Institute

Frequently Asked Questions about L2C By Maria Nemchuk November 26, 2024 Breadcrumb Home Frequently Asked Questions about L2C Answers to some of the most common questions we receive are listed below as a resource for researchers, physicians, patients, caregivers, and patient advocacy groups. Please feel free to contact us with additional questions. As a note, we cannot offer medical advice or interpret test results.

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Program Tripled Number of Completed At-Home Colon Cancer Tests

Drugs.com

TUESDAY, Nov. 26, 2024 -- People are three times more likely to undergo at-home colon cancer screening if they’re provided a free test, a new study says.About 30% of patients mailed a free stool test kit completed their screening within six months.

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People

Broad Institute

People By Maria Nemchuk November 26, 2024 Breadcrumb Home People Leadership Anna Greka : Founder and Chair L2C Accelerator Wendy Chung : Co-Chair L2C Accelerator Team Jillian Shaw: Senior Scientific Advisor L2C Accelerator Ed McBride: Associate Director of Project Management Katie Liguori: Operations Specialist Scientists and Collaborators Sumaiya Iqbal Mehrtash Babadi Stacey Gabriel Heidi Rehm Paul Blainey John Doench Anne Carpenter Niall Lennon Aziz Al’Khafaji Tim Tickle Sarah Morton Rajat Gup

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Preschoolers' Tantrums Can Be Early Sign of ADHD

Drugs.com

TUESDAY, Nov. 26, 2024 -- Preschoolers prone to tantrums appear to have a higher risk of attention-deficit/hyperactivity disorder (ADHD) by the time they reach school age, a new study says.Young children who struggle to control their emotions and.

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Bun 1.0: Transforming JavaScript Development with Speed and Efficiency

Perficient: Drug Development

In the ever-evolving landscape of JavaScript development, speed, efficiency, and simplicity are the key players. Enter Bun 1.0, a groundbreaking JavaScript runtime & toolkit designed to elevate your development process to unparalleled heights. In this comprehensive blog, we will delve into the world of Bun 1.0, exploring its features, benefits, and how it is reshaping how developers build and test JavaScript and TypeScript projects.

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Mom's Healthy Diet in Pregnancy Pays Big Dividends for Baby

Drugs.com

TUESDAY, Nov. 26, 2024 -- Moms who eat right during pregnancy are setting their kids up for good health, a new study says.Expectant mothers who ate a quality diet were more likely to have kids with healthy birth weights, steadier growth patterns.

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Lumen – A light weight framework

Perficient: Drug Development

Laravel is a popular, open-source PHP web framework designed to make web development easier and more efficient by offering a range of built-in tools and features. It is widely known for its powerful and feature-rich framework, but for smaller, high-performance applications, Laravel’s full stack may not always be necessary. In such cases, Lumen, a lightweight micro-framework built by the creators of Laravel, is a fantastic alternative.

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Scientists Spot Gene That Could Help Cause Miscarriages

Drugs.com

TUESDAY, Nov. 26, 2024 -- A gene that causes accelerated reproductive aging is directly tied to the risk of miscarriage in younger women, a new study says.A mutation of the gene KIF18A speeds up the aging process of eggs in younger women.

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Why Immutability Matters in Redux: A Guide to Better State Management

Perficient: Drug Development

Introduction Redux, a predictable state container for JavaScript applications, relies on the principle of immutability to manage state changes efficiently. In this blog post, we’ll explore what immutability is, why it’s crucial in the context of Redux, and how it simplifies state management. Understanding Immutability Immutability refers to the state of being unchangeable.

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Long COVID Brain Fog: Could the Lungs Hold Clues?

Drugs.com

TUESDAY, Nov. 26, 2024 -- The “brain fog” of long COVID might be due to impaired lung function following a person’s infection, a new small-scale study says.Reduced gas exchange in the lungs – oxygen coming in, carbon dioxide going out -- appears to.

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Meet the ZoBio SPR Team: Advancing Drug Discovery Around the Clock

Zobio

Drug discovery doesn’t sleep, and neither does our SPR (Surface Plasmon Resonance) team. While the Assay Group takes a well-deserved weekend break and goes for dinner tonight, our relentless SPR team is tirelessly screening compounds, revealing critical insights that help drive discovery forward. Meet the Team: Each of our SPR machines brings unique strengths to the lab, earning their names and personalities for how they support our research.

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Concussions Slow Brain Activity in High School Football Players

Drugs.com

TUESDAY, Nov. 26, 2024 (HeathDay News) -- A potentially important form of brain signaling appears to be affected whenever concussion strikes, according to new research involving high school football players.“This study is important because it p.