Wed.Jul 24, 2024

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Scientists assess how large dinosaurs could really get

Science Daily: Pharmacology News

A study looks at the maximum possible sizes of dinosaurs, using the carnivore, Tyrannosaurus rex, as an example. Using computer modelling, experts produced estimates that T. Rex might have been 70% heavier than what the fossil evidence suggests.

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Big Drop in U.S. Kids, Teens Misusing Prescription Meds

Drugs.com

WEDNESDAY, July 24, 2024 -- Misuse of illicit prescription drugs is falling dramatically among U.S. high school students, a new study says.The percentage of seniors who say they’ve misused prescription drugs in the past year has dropped to 2% in 2.

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New study confirms mammal-to-mammal avian flu spread

Science Daily: Pharmacology News

A new study provides evidence that a spillover of avian influenza from birds to dairy cattle across several U.S. states has now led to mammal-to-mammal transmission -- between cows and from cows to cats and a raccoon.

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More Americans With Diabetes Are Turning to Marijuana

Drugs.com

WEDNESDAY, July 24, 2024 -- As marijuana loses much of its stigma and laws around its use relax, Americans are increasingly consuming it medically and recreationally.Americans with diabetes are no exception, a new study finds. The number of adults.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Neuroscientists discover brain circuitry of placebo effect for pain relief

Science Daily: Pharmacology News

Researchers have discovered a novel pain control pathway that links the cingulate cortex in the front of the brain, through the pons region of the brainstem, to cerebellum in the back of the brain.

Research 121
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Huge Warehouses Can Create Unhealthy Neighborhoods

Drugs.com

WEDNESDAY, July 24, 2024 -- Online retail giants like Amazon have made it easier for people to buy what they want when they want it, but that convenience comes at a cost to people’s health, a new study says.Huge warehouses that support online s.

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Average Hip, Knee Replacement Patient May Be Getting Younger

Drugs.com

WEDNESDAY, July 24, 2024 -- Brent Ruch, a collegiate basketball center, opted to have his left knee replaced at age 35 after struggling with pain for years.“Walking with a limp and living with a consistent aching pain was physically and emotionally.

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Komodo dragons have iron-coated teeth to rip apart their prey

Science Daily: Pharmacology News

Scientists have discovered that the serrated edges of Komodo dragons' teeth are tipped with iron. The study gives new insight into how Komodo dragons keep their teeth razor-sharp and may provide clues to how dinosaurs like Tyrannosaurus rex killed and ate their prey.

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Arizona Health Officials Warn of Uptick in Hantavirus Cases

Drugs.com

WEDNESDAY, July 24, 2024 -- Arizona health officials are reporting an increase in hantavirus infections, which are spread by rodents and can cause severe respiratory illness.In a recent health alert, the Arizona Department of Health Services.

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Nanoscale device simultaneously steers and shifts frequency of optical light, pointing the way to future wireless communication channels

Science Daily: Pharmacology News

A tunable metasurface can control optical light in space and time, offering a path toward new ways of wirelessly and securely transmitting large amounts of data both on Earth and in space.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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COVID-19 Won't Raise Odds for Chronic Fatigue Syndrome: Study

Drugs.com

WEDNESDAY, July 24, 2024 -- COVID-19 doesn’t raise a person’s risk of developing chronic fatigue syndrome more than any other infectious disease, a new study finds.The rate of chronic fatigue syndrome following a brief illness was roughly the same b.

Disease 105
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Whale shark tracked for record-breaking four years

Science Daily: Pharmacology News

Researchers have been tracking a 26-foot endangered whale shark -- named 'Rio Lady' -- with a satellite transmitter for more than four years -- a record for whale sharks and one of the longest tracking endeavors for any species of shark.

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Autobahn raises $100M on investor interest in neuropsych drugs

BioPharma Drive: Drug Pricing

Autobahn’s lead candidate is designed to stimulate thyroid hormone receptors as a way to complement existing antidepressants.

Drugs 116
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New study supports stable mantle chemistry dating back to Earth's early geologic history and over its prodigious evolution

Science Daily: Pharmacology News

A new analysis of rocks thought to be at least 2.5 billion years old helps clarify the chemical history of Earth's mantle -- the geologic layer beneath the planet's crust. The findings hone scientists' understanding of Earth's earliest geologic processes, and they provide new evidence in a decades-long scientific debate about the geologic history of Earth.

Research 101
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Risk of Mental Illness Rises for Kids Treated in ICUs

Drugs.com

WEDNESDAY, July 24, 2024 -- Youngsters so sick they’ve needed treatment in an ICU appear to bear the scars of that experience years later, a new study finds.Children and teenagers treated in an intensive care unit have a significantly higher risk o.

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How Rembrandt combined special pigments for golden details of The Night Watch

Science Daily: Pharmacology News

Chemists have for the first time established how Rembrandt applied special arsenic sulfide pigments to create a 'golden' paint.

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CDC Warns of Shortage of Bottles Needed for Crucial Blood Tests

Drugs.com

WEDNESDAY, July 24, 2024 -- Hospitals and clinical laboratories across the United States are facing a critical shortage of bottles used to culture blood samples, federal health officials report.Without the ability to culture blood, patients might.

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Trees reveal climate surprise -- bark removes methane from the atmosphere

Science Daily: Pharmacology News

Tree bark surfaces play an important role in removing methane gas from the atmosphere.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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The Future of Drug Discovery: Tackling the Undruggable with New Biotechnologies

DrugBank

In the constantly evolving field of drug discovery, the term “undruggable” refers to proteins and targets in the body that, until recently, were considered impossible to treat with traditional drugs. Thanks to emerging technologies and innovative pharmacological tools, we’re expanding our "drug discovery toolbox" and finding ways to tackle these tough targets.

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Researchers record images and data of a shark experiencing a boat strike

Science Daily: Pharmacology News

Researchers have captured what they believe is the first ever video of a shark or any large marine animal being struck by a boat.

Research 112
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Drafting Detailed Drug Patent Claims: The Art and Science of Pharmaceutical IP Protection

Drug Patent Watch

In the high-stakes world of pharmaceutical innovation, drafting detailed drug patent claims is a critical process that can make or break a company’s future.

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Dark matter flies ahead of normal matter in mega galaxy cluster collision

Science Daily: Pharmacology News

Astronomers have untangled a messy collision between two massive clusters of galaxies in which the clusters' vast clouds of dark matter have decoupled from the so-called normal matter.

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Twice-Yearly Shot Protects At-Risk Women Against HIV

Drugs.com

WEDNESDAY, July 24, 2024 -- Just two shots a year of an HIV treatment provided complete protection against infections in highly at-risk women, researchers reported Wednesday.In the study of about 5,000 women in South Africa and Uganda, those given.

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Images of nearest 'super-Jupiter' open a new window to exoplanet research

Science Daily: Pharmacology News

Using the James Webb Space Telescope (JWST), astronomers imaged a new exoplanet that orbits a star in the nearby triple system Epsilon Indi. The planet is a cold super-Jupiter exhibiting a temperature of around 0 degrees Celsius and a wide orbit comparable to that of Neptune around the Sun. This measurement was only possible thanks to JWST's unprecedented imaging capabilities in the thermal infrared.

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Biologic Product Hopping: Innovation or Market Manipulation?

Drug Patent Watch

As patents expire on blockbuster biologic drugs, manufacturers are increasingly employing a controversial tactic known as “product hopping” to maintain […] Source

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Building a molecular brain map to understand Alzheimer's disease

Science Daily: Pharmacology News

Resulting atlas of the aging human brain holds molecular insights into the brain's vulnerability and resilience.

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The Regulatory Maze: How Generic Drugs Navigate FDA Approval

Drug Patent Watch

In the high-stakes world of pharmaceuticals, generic drugs have become the unsung heroes of healthcare accessibility.

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New groups of methane-producing organisms in Yellowstone

Science Daily: Pharmacology News

The team verified that microbes found in Yellowstone National Park hot springs produce methane to grow.

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Novartis invests in bispecifics for cancer; Bob Langer steps down from Moderna board

BioPharma Drive: Drug Pricing

The Swiss pharma is paying Dren Bio $150 million to partner on “targeted myeloid engagers.” Elsewhere, Geron is losing its commercial chief and Biovectra will sell to Agilent for $925 million.

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Research Confirms Chronic High Blood Pressure's Link to Stroke

Drugs.com

WEDNESDAY, July 24, 2024 -- Having high blood pressure in adulthood greatly raises the odds for multiple types of stroke, a new study confirms.“Our results suggest that early diagnosis and sustained control of high blood pressure over the lifespan a.

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PBMs battle bipartisan scrutiny as lawmakers eye reforms

BioPharma Drive: Drug Pricing

Top executives at CVS Caremark, Optum Rx and Express Scripts made a rare congressional appearance to defend their companies’ drug pricing policies.

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Better Screening Key to Closing U.S. 'Race Gap' in Colon Cancer Deaths

Drugs.com

WEDNESDAY, July 24, 2024 -- Black Americans are almost a third more likely to die from colon cancer than their white peers, and one key to closing that divide could be better cancer screening, a new report finds.That means getting Black Americans.

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Part three: pragmatic guidelines to getting the best out of LLMs

Drug Target Review

In our previous article, published Monday 15 July, we presented a simple case example to download and practise with ChatGPT, 1 or other accessible LLM systems. In this article, we address the challenging topic of guidelines that will lead to useful scientific insights. Thank you to Nina Truter 2 for her support. The guidelines are separated into two sections: those specific to using ChatGPT, and those to use when deciding on which LLM system to use.