Drug Discovery World
JANUARY 9, 2024
Thirteen new-to-market therapeutics and drugs poised to launch in 2024 will achieve ‘blockbuster’ status by 2029 or deliver game-changing benefits to patients. They include therapeutics for conditions including breast cancer, haemophilia A, sickle cell disease, Crohn’s disease, ulcerative colitis, respiratory syncytial virus (RSV) and multiple myeloma, among others.
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan. 9, 2024 -- HIV pre-exposure prophylaxis (PrEP) is a lifeline for Americans, many of them gay men, who are at high risk of contracting the virus that causes AIDS.But a case that is winding its way through the court system might push.
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Drug Discovery World
JANUARY 9, 2024
In a first for 2024, DDW will be hosting the SLAS Ignite Theater track on the theme of ‘Innovation & technology: from lab to patient’. It will take place at SLAS2024 in Boston on 5 and 6 February 2024 and is co-sponsored by Integra Biosciences and Hamamatsu Corporation. Simon Bushell DDW is delighted to announce that the programme will feature Simon Bushell, SVP of Molecular Discovery of Entact Bio.
BioPharma Drive: Drug Pricing
JANUARY 9, 2024
Albert Bourla acknowledged Pfizer’s difficult 2023, while a biotech CEO spoke with BioPharma Dive about building neuroscience startups.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
JANUARY 9, 2024
Merck has agreed a deal with Inspirna for ompenaclid (RGX-202), a first-in-class oral inhibitor of the creatine transport channel SLC6A8 and SLC6A8-targeting follow-on compounds. Ompenaclid is currently being evaluated in a Phase II study for the second-line treatment of RAS-mutated (RASmut) advanced or metastatic colorectal cancer (mCRC). “Over the past decade, the treatment paradigm for patients with RAS-mutated CRC, accounting for approximately 45% of the second-line population, has not seen
Drug Patent Watch
JANUARY 9, 2024
A recent story by NPR echoes the findings of a collaboration between DrugPatentWatch and Bloomberg, which examined increasing competition between generic drug makers. The NPR article discusses the challenges in… The post NPR on how low Drug Prices can Shortages appeared first on DrugPatentWatch - Make Better Decisions.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Perficient: Drug Development
JANUARY 9, 2024
Medical device industry trends for 2024. The medical device industry is in a constant state of evolution. We are seeing more sophisticated consumer expectations, advancements in technology, regulatory changes, and changing healthcare needs – just to name a few. As we gaze into our crystal ball, five key trends have bubbled up. Let’s look at what is poised to impact the medical device industry in 2024.
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan. 9, 2024 -- Eight Philadelphia residents are known to have contracted measles, the city's department of health said in an update on the outbreak released Monday.Measles is highly infectious, and Philadelphia health care staff are.
Science Daily: Pharmacology News
JANUARY 9, 2024
As the potter works the spinning wheel, the friction between their hands and the soft clay helps them shape it into all kinds of forms and creations. In a fascinating parallel, sea squirt oocytes (immature egg cells) harness friction within various compartments in their interior to undergo developmental changes after conception.
Drug Channels
JANUARY 9, 2024
For 2024, the three largest pharmacy benefit managers (PBMs)—Caremark (CVS Health), Express Scripts (Cigna), and OptumRx (United Health Group)—have again each excluded 600 or more drugs from their standard formularies. You can find our updated counting below. This year, Humira and its 13 biosimilars will provide the most intriguing formulary drama. Unfortunately, the gross-to-net bubble will remain a fixture for this category, despite a price war led by almost half of the biosimilars.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan.9, 2024 -- Patients with the most common form of pancreatic cancer could benefit from an experimental therapeutic vaccine, a small new clinical trial shows.The vaccine, called ELI-002 for now, is targeted to what are known as.
Science Daily: Pharmacology News
JANUARY 9, 2024
Astronomers have found a brown dwarf (an object more massive than Jupiter but smaller than a star) with infrared emission from methane, likely due to energy in its upper atmosphere. This is an unexpected discovery because the brown dwarf, W1935, is cold and lacks a host star; therefore, there is no obvious source for the upper atmosphere energy. The team speculates that the methane emission may be due to processes generating aurorae.
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan. 9, 2024 -- A 'secret shopper' study finds that for many American families, accessing inpatient treatment for a teen battling addiction can be next to impossible.“If you are a family in crisis and you have a kid for whom outpatient.
Science Daily: Pharmacology News
JANUARY 9, 2024
Analysis of iron meteorites from the earliest years of the solar system indicate that the planetary 'seeds' that ultimately formed Earth contained water.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan. 9, 2024 -- It's an approach that's becoming more widespread: Receiving hospital-level care in the home.A new study finds that folks "hospitalized" at home tend to do at least as well as if they’d been checked into a hospital for.
NIOSH Science Blog: Drugs
JANUARY 9, 2024
A recent webinar from the National Occupational Research Agenda’s Cancer, Reproductive, Cardiovascular, and Other Chronic Disease Prevention (CRC) cross-sector council describes research related to the potential effects of occupational physical activity on workers’ cardiovascular health. This blog summarizes the webinar and discusses the differences between (1) leisure-time physical activity, and (2) occupational physical activity in relation to cardiovascular health and other potential health c
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan. 9, 2024 — Teens who are active are doing their bones a lasting favor, Japanese researchers report."Physical exercise in adolescence affects BMD [bone mineral density] more than 50 years later in older adults," said lead researcher.
SCIENMAG: Medicine & Health
JANUARY 9, 2024
Amsterdam, January 9, 2024 – The Journal of Alzheimer’s Disease (JAD), published by IOS Press, is pleased to announce the appointment of new co-Editor-in-Chief, Paula I. Moreira, PhD. Dr.
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan. 9, 2024 -- An average of 22 U.S. teens die each week from drug overdoses, a death toll driven by the powerful synthetic opioid fentanyl, a new study reports.Researchers also have identified 19 “hotspot” counties where fatal ODs.
SCIENMAG: Medicine & Health
JANUARY 9, 2024
Key takeaways Credit: American College of Surgeons Key takeaways The prevalence and severity of scooter-related injuries, as well as associated health care costs, have significantly increased in the U.S. Compared to bicycle-related injuries, scooter-related injuries more often require surgical management and are associated with greater risks of long bone fractures and paralysis.
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan. 9, 2024 -- "School spirit" appears to provide long-lasting mental health benefits for Black teens, new research finds.School connectedness – the degree to which students feel like part of to their school community – is a.
SCIENMAG: Medicine & Health
JANUARY 9, 2024
Humans are protected by two branches of the immune system. Innate immunity provides built-in defense against widespread characteristics of bacteria and viruses, while adaptive immunity memorizes individual pathogens that a person has already encountered. Vaccines teach the adaptive immune system about new pathogens without having to go through an actual infection.
Science Daily: Pharmacology News
JANUARY 9, 2024
In summer 2022, astronomers detected the most powerful and most distant fast radio burst (FRB) ever observed. Now, astronomers have pinpointed the extraordinary object's birthplace -- and it's rather curious, indeed. Using images from NASA's Hubble Space Telescope, the researchers traced the FRB back to not one galaxy but a group of at least seven galaxies.
SCIENMAG: Medicine & Health
JANUARY 9, 2024
Prof. Sun-Uk Lee of the Department of Neurology and Prof. Euyhyun Park of the Department of Otorhinolaryngology from Korea University’s Anam Hospital discovered a new mechanism of vestibular neuritis. Credit: none Prof. Sun-Uk Lee of the Department of Neurology and Prof.
BioPharma Drive: Drug Pricing
JANUARY 9, 2024
Aiolos, which raised a Series A round three months ago, is developing an antibody that shares a target with Amgen and AstraZeneca’s Tezspire.
SCIENMAG: Medicine & Health
JANUARY 9, 2024
BINGHAMTON, N.Y. — Researchers from Binghamton University, State University of New York are unraveling the workings of Group B Strep (GBS) infections in pregnant women, which could someday lead to a vaccine. Credit: “pregnant woman” by kylieaquino01 is marked with Public Domain Mark 1.0. BINGHAMTON, N.Y.
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan. 9, 2024 -- Social media is abuzz with the possibility that newfangled weight loss drugs can also reduce cravings for alcohol, a new study says.Across a number of Reddit threads, users of weight-loss drugs like Ozempic reported that.
SCIENMAG: Medicine & Health
JANUARY 9, 2024
Brown fat cells convert energy into heat – a key to eliminating unwanted fat deposits. In addition, they also protect against cardiovascular diseases.
New Drug Approvals
JANUARY 9, 2024
Tacaciclib 2768774-66-7 AUR-102 Tacaciclib SCHEMBL24548621 GTPL12880 528.6 g/mol C 30 H 36 N 6 O 3 INN 12755 UNI D3G4JKK1MA (2 S )- N -(5-cyclopropyl-1 H -pyrazol-3-yl)-3-methyl-2-[3-[6-[[( E )-4-morpholin-4-ylbut-2-enoyl]amino]pyridin-3-yl]phenyl]butanamide (αS)-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-α-(1-methylethyl)-3-[6-[[(2E)-4-(4-morpholinyl)-1-oxo-2-buten-1-yl]amino]-3-pyridinyl]benzeneacetamide Benzeneacetamide, N-(5-cyclopropyl-1H-pyrazol-3-yl)-α-(1-methylethyl)-3-[6-[[(2E)-4-(4-morpholinyl)
Drug Patent Watch
JANUARY 9, 2024
Annual Drug Patent Expirations for EXPAREL Exparel is a drug marketed by Pacira Pharms Inc and is included in one NDA. It is available from one supplier. There are nine… The post New patent for Pacira Pharms drug EXPAREL appeared first on DrugPatentWatch - Make Better Decisions.
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan. 9, 2024 -- Depression that emerges around the time of pregnancy raises a woman's risk for suicide sharply and for many years, new Swedish research shows.The study found that a new mom's odds for suicide soars seven-fold in the year.
Drug Patent Watch
JANUARY 9, 2024
Annual Drug Patent Expirations for SUBLOCADE Sublocade is a drug marketed by Indivior and is included in one NDA. It is available from one supplier. There are eleven patents protecting… The post New patent for Indivior drug SUBLOCADE appeared first on DrugPatentWatch - Make Better Decisions.
Fierce BioTech
JANUARY 9, 2024
2024 Drugs to Watch: From R&D Promise to In-market Wins swheeler Tue, 01/09/2024 - 17:53 Tue, 02/20/2024 - 10:00 Resource Type Webinar Mike Ward Renée Aguiar-Lucander Duration 60 minutes Lessons from companies featured in the 2024 Drugs to Watch Report™ This webinar delves into the strategic transformation of research and development (R&D) companies into thriving commercial entities, whether taking on established big pharma incumbents, focusing on orphan diseases, or launching first-in-class med
Drug Patent Watch
JANUARY 9, 2024
Annual Drug Patent Expirations for QINLOCK Qinlock is a drug marketed by Deciphera Pharms and is included in one NDA. It is available from one supplier. There are nineteen patents… The post New patent for Deciphera Pharms drug QINLOCK appeared first on DrugPatentWatch - Make Better Decisions.
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