Mon.Jun 03, 2024

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A technique for more effective multipurpose robots

Science Daily: Pharmacology News

MIT researchers developed a technique to combine robotics training data across domains, modalities, and tasks using generative AI models. They create a combined strategy from several different datasets that enables a robot to learn to perform new tasks in unseen environments.

Research 141
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Structure pill leads to competitive weight loss in obesity study

BioPharma Drive: Drug Pricing

Shares in the company soared by more than 50% as study data showed the pill led to similar levels of weight loss as a rival drug being developed by Eli Lilly.

Drugs 122
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The embryo assembles itself

Science Daily: Pharmacology News

Biological processes depend on puzzle pieces coming together and interacting. Under specific conditions, these interactions can create something new without external input. This is called self-organization, as seen in a school of fish or a flock of birds. Interestingly, the mammalian embryo develops similarly. Scientists now introduce a mathematical framework that analyzes self-organization from a single cell to a multicellular organism.

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U.S. Will Make Millions of Bird Flu Vaccines This Summer

Drugs.com

MONDAY, June 3, 2024 -- As the H5N1 avian flu continues to spread among dairy cows in the United States, nearly 5 million doses of flu vaccine are now being prepared for possible use in humans.Since the outbreak in livestock began this spring, bird.

Vaccine 115
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Fungus breaks down ocean plastic

Science Daily: Pharmacology News

A fungus living in the sea can break down the plastic polyethylene, provided it has first been exposed to UV radiation from sunlight. Researchers expect that many more plastic degrading fungi are living in deeper parts of the ocean.

Research 134
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Lack of Insurance Keeps Many Americans From Best Cancer Meds

Drugs.com

MONDAY, June 3, 2024 -- A cutting-edge class of drugs is saving and extending the lives of cancer patients.But the drugs, called immune checkpoint inhibitors (ICIs), are so expensive that some uninsured Americans can't access them, a new report.

Drugs 111

More Trending

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Male Birth Control Gel Shows Promise in Trial

Drugs.com

MONDAY, June 3, 2024 -- A new hormonal gel could one day be a potential form of birth control for men, researchers reported Sunday.“The development of a safe, highly effective and reliably reversible contraceptive method for men is an unmet need,” s.

Trials 105
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Altered carbon points toward sustainable manufacturing

Science Daily: Pharmacology News

Researchers develop a vastly more productive way to convert carbon dioxide into useful materials and compounds.

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Oral cancer medications: The adherence paradox

BioPharma Drive: Drug Pricing

The number of oral cancer medications is increasing, opening new possibilities for improved convenience, but some studies show much lower adherence rates with oral oncolytics.

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Thawing permafrost: Not a climate tipping element, but nevertheless far-reaching impacts

Science Daily: Pharmacology News

Permafrost soils store large quantities of organic carbon and are often portrayed as a critical tipping element in the Earth system, which, once global warming has reached a certain level, suddenly and globally collapses. Yet this image of a ticking timebomb, one that remains relatively quiet until, at a certain level of warming, it goes off, is a controversial one among the research community.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Perficient Launches PRISM Employee Resource Group

Perficient: Drug Development

New ERG Will Further Perficient’s Progress in Supporting and Empowering the LGBTQ+ Community and its Allies At Perficient, we believe in developing a workforce that is as diverse and inclusive as the clients we work with. We are committed to fostering an environment where we celebrate all colleagues because our people make us unique, their perspectives make us stronger, and the label we all share is talent.

Marketing 105
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How sharks survived a major spike in Earth's temperature

Science Daily: Pharmacology News

The sharks we know today as the open ocean's top predators evolved from stubby bottom dwellers during a dramatic episode of global warming millions of years ago.

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A true liquid biopsy hub – Menarini Silicon Biosystem

BioPharma Drive: Drug Pricing

Liquid biopsy has emerged as a revolutionary tool for clinical trials, offering cellular and cell-free methods that provide valuable insights into disease progression and treatment response.

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Food drove the evolution of giraffes' long neck

Science Daily: Pharmacology News

A study explores body proportions of Masai giraffes, lending insight into why giraffes have such long necks and how this trait might have evolved.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Scientists Spot Gene Behind Form of Intellectual Disability Affecting Thousands Worldwide

Drugs.com

MONDAY, June 3, 2024 -- Mutations in a single newly identified gene are responsible for developmental disorders affecting tens of thousands of people worldwide, a new study claims.The gene – RNU4-2 – can cause a collection of developmental symptoms t.

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Kinship and ancestry of the Celts in Baden-Württemberg, Germany

Science Daily: Pharmacology News

The Celtic culture of the pre-Roman Iron Age in Western and Central Europe has left numerous traces to this day, not least in the form of enormous burial mounds and spectacular archaeological artifacts. Despite this rich legacy, much about this civilization remains hidden from us.

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Sleep Apnea Treatment Can Give Couples' Bond a Boost

Drugs.com

MONDAY, June 3, 2024 -- Strapping a mask to your face can make for a happier marriage, a new study suggests.Relationships with partners flourish if a person with sleep apnea starts using a continuous positive air pressure (CPAP) machine on a.

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Crucial shift in River Nile's evolution during ancient Egypt discovered

Science Daily: Pharmacology News

Researchers have explored how the River Nile evolved over the past 11,500 years and how changes in its geography could have helped shape the fortunes of ancient Egyptian civilization. Research reveals a major shift in the Nile around four thousand years ago, after which the floodplain in the Nile Valley around Luxor greatly expanded.

Research 117
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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FDA Warns of Bacterial and Other Dangers From Recalled Infant Formula

Drugs.com

MONDAY, June 3, 2024 -- The U.S. Food and Drug Administration is warning parents about a goat milk infant formula potentially tainted with a bacterium that's very dangerous to babies.Crecelac brand formula, already under recall since May 24, could.

FDA 98
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Eli Lilly adds ALS drug prospect with QurAlis deal

BioPharma Drive: Drug Pricing

The alliance hands Lilly an RNA-based therapy in preclinical testing for ALS and frontotemporal dementia, and includes a research collaboration to develop other, similar medicines.

RNA 87
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GLP-1 Weight Loss Meds Might Keep Your Pancreas Healthy

Drugs.com

MONDAY, June 3, 2024 -- Ozempic and Wegovy might help lower the risk of pancreatitis in patients with obesity and type 2 diabetes, a new study says.Up to now, doctors have been cautious about prescribing semaglutide to patients with a history of.

Doctors 98
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Fresh findings: Earliest evidence of life-bringing freshwater on Earth

Science Daily: Pharmacology News

New research has found evidence that fresh water on Earth, which is essential for life, appeared about four billion years ago -- five hundred million years earlier than previously thought.

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Nerve Surgery May Help Some Battling Severe Migraine

Drugs.com

MONDAY, June 3, 2024 -- Nerve surgery can reduce the number of headache days for people who suffer frequent migraines, a new review finds.The procedure also can decrease the frequency and intensity of migraine attacks, according to results.

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ASCO24: Tagrisso in the spotlight, Caribou’s adjustment and Lilly’s KRAS competitor

BioPharma Drive: Drug Pricing

AstraZeneca’s targeted therapy could see wider use after ASCO data. Elsewhere, Caribou sought to course correct and Lilly talked up its next cancer drug.

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Could New Weight-Loss Drugs Be Changing Women's Taste for Sweets?

Drugs.com

MONDAY, June 3, 2024 -- Ozempic and Wegovy appear to improve people’s sensitivity to tastes, potentially lowering their desire for sweets, a new study suggests.The active ingredient in the weight-loss medications, semaglutide, also appears to a.

Drugs 96
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Thinking inside the box: How SmartLabs is supporting the science of tomorrow

BioPharma Drive: Drug Pricing

With new modalities such as gene and cell therapies, RNA therapeutics, complex biologics and more, today’s science brings unprecedented opportunities to address diseases that have long remained out of reach.

Science 59
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Gene-Targeted Immunotherapy Boosts Survival for Some Colon Cancer Patients

Drugs.com

MONDAY, June 3, 2024 -- There's potential good news for a sizable minority of people battling advanced colon cancer.Doctors in Britain say that an immunotherapy drug, given before surgery, can help many more patients with a specific genetic profile.

Drugs 96
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Honing Your Vault RIMS Environment for Peak Performance

thought leadership

Regulatory requirements are a formidable challenge for early stage biotechs and top pharma alike. As health authorities continually revise guidelines across diverse markets, companies are tasked with swift adaption to changing regulations. The cost of non-compliance is high: recalls and sanctions may gravely harm a company’s reputation, especially in an industry where patient trust is paramount.

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Better Sleep Might Bring Less Loneliness

Drugs.com

MONDAY, June 3, 2024 -- People who feel lonely and socially isolated might benefit from more sleep, especially if they’re a young adult, a new study suggests.Better sleep is associated with significantly less emotional and social loneliness, r.

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NIOSH Risk Assessment of Engineered Nanomaterials

NIOSH Science Blog: Drugs

Nanotechnology as we know it today did not exist at the time of the Occupational Safety and Health Act of 1970. Yet, its provisions to “assure safe and healthful working conditions” apply to nanotechnology workplaces and other workplaces where engineered nanomaterials are produced or used. Engineered nanomaterials are used in a variety of products and applications, including in energy, electronics, transportation, environmental remediation, and medicine.

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The OIG Don’t Like That: Rockin’ The Casbah, Rockin’ the Casbah

FDA Law Blog: Biosimilars

By Jeffrey N. Wasserstein — Today’s email brings an interesting, and somewhat confusing settlement of what should have been an ordinary antikickback statute case , and may bring about a clash between what many companies do and what the government may be objecting to. Or, perhaps your loyal blogger is reading too much into a brief settlement document.

Doctors 52
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5 Essentials for Building a Robust Target Product Profile

The Premier Consulting Blog

Author: William Bainbridge A Target Product Profile (TPP) serves as the primary strategic framework that aligns commercial and clinical workstreams. When properly defined, the TPP enables drug developers to manage the development equation of risk x cost x time = success, and it starts by keeping the end in mind. Defining the needs of patients, physicians, and payers early in the process ensures a commercially viable product with a potentially higher valuation.

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Treating immune-mediated diseases with nanoparticles

Drug Target Review

How does COUR Pharmaceuticals’ immune-modifying nanoparticle platform differ from traditional approaches to treating immune-mediated diseases? Most traditional approaches for treating autoimmune and inflammatory diseases treat the inflammatory mediator by trying to either remove or suppress it, for example removal of B cells non-specifically or killing T cells non-specifically that ultimately lead to broad immunosuppression.

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