Drug Discovery World
JUNE 3, 2024
Thousands of cancer patients in England are set to gain fast-tracked access to trials of mRNA personalised cancer vaccines following the launch of an NHS trial ‘matchmaking’ service to help find new life-saving treatments. The vaccines being jointly developed by biopharmaceutical companies BioNTech and Genentech are still undergoing trials and have not yet been approved by regulators.
Science Daily: Pharmacology News
JUNE 3, 2024
MIT researchers developed a technique to combine robotics training data across domains, modalities, and tasks using generative AI models. They create a combined strategy from several different datasets that enables a robot to learn to perform new tasks in unseen environments.
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Drug Discovery World
JUNE 3, 2024
Previously untreated follicular lymphoma (FL) patients who received epcoritamab with rituximab-lenalidomide (R2) had a 95% overall response rate (ORR), according to preliminary trial data. The results of two ongoing Phase I/II clinical trials evaluating epcoritamab, a T-cell engaging bispecific antibody, were shared at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, in Chicago, US.
Science Daily: Pharmacology News
JUNE 3, 2024
A fungus living in the sea can break down the plastic polyethylene, provided it has first been exposed to UV radiation from sunlight. Researchers expect that many more plastic degrading fungi are living in deeper parts of the ocean.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
JUNE 3, 2024
New data show that an unprecedented 60% of patients with advanced lung cancer given Lorbrena (lorlatinib) remain alive without disease progression after five years. The trial results also demonstrated an 81% reduction in risk of progression or death and 94% reduction in progression of brain metastases compared to Xalkori (crizotinib). The Phase III CROWN trial evaluated the third-generation ALK inhibitor in people with previously untreated, anaplastic lymphoma kinase (ALK)-positive advanced non-
Science Daily: Pharmacology News
JUNE 3, 2024
An international research team has sparked interest in the scientific community with results in quantum physics. In their current study, the researchers reinterpret the Higgs mechanism, which gives elementary particles mass and triggers phase transitions, using the concept of 'magnetic quivers.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
JUNE 3, 2024
Shares in the company soared by more than 50% as study data showed the pill led to similar levels of weight loss as a rival drug being developed by Eli Lilly.
Science Daily: Pharmacology News
JUNE 3, 2024
The Celtic culture of the pre-Roman Iron Age in Western and Central Europe has left numerous traces to this day, not least in the form of enormous burial mounds and spectacular archaeological artifacts. Despite this rich legacy, much about this civilization remains hidden from us.
Drugs.com
JUNE 3, 2024
MONDAY, June 3, 2024 -- A cutting-edge class of drugs is saving and extending the lives of cancer patients.But the drugs, called immune checkpoint inhibitors (ICIs), are so expensive that some uninsured Americans can't access them, a new report.
Science Daily: Pharmacology News
JUNE 3, 2024
The sharks we know today as the open ocean's top predators evolved from stubby bottom dwellers during a dramatic episode of global warming millions of years ago.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
JUNE 3, 2024
MONDAY, June 3, 2024 -- A new hormonal gel could one day be a potential form of birth control for men, researchers reported Sunday.“The development of a safe, highly effective and reliably reversible contraceptive method for men is an unmet need,” s.
Perficient: Drug Development
JUNE 3, 2024
New ERG Will Further Perficient’s Progress in Supporting and Empowering the LGBTQ+ Community and its Allies At Perficient, we believe in developing a workforce that is as diverse and inclusive as the clients we work with. We are committed to fostering an environment where we celebrate all colleagues because our people make us unique, their perspectives make us stronger, and the label we all share is talent.
Science Daily: Pharmacology News
JUNE 3, 2024
A study explores body proportions of Masai giraffes, lending insight into why giraffes have such long necks and how this trait might have evolved.
BioPharma Drive: Drug Pricing
JUNE 3, 2024
The number of oral cancer medications is increasing, opening new possibilities for improved convenience, but some studies show much lower adherence rates with oral oncolytics.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
JUNE 3, 2024
MONDAY, June 3, 2024 -- Strapping a mask to your face can make for a happier marriage, a new study suggests.Relationships with partners flourish if a person with sleep apnea starts using a continuous positive air pressure (CPAP) machine on a.
BioPharma Drive: Drug Pricing
JUNE 3, 2024
Liquid biopsy has emerged as a revolutionary tool for clinical trials, offering cellular and cell-free methods that provide valuable insights into disease progression and treatment response.
Drugs.com
JUNE 3, 2024
MONDAY, June 3, 2024 -- The U.S. Food and Drug Administration is warning parents about a goat milk infant formula potentially tainted with a bacterium that's very dangerous to babies.Crecelac brand formula, already under recall since May 24, could.
Science Daily: Pharmacology News
JUNE 3, 2024
Researchers have explored how the River Nile evolved over the past 11,500 years and how changes in its geography could have helped shape the fortunes of ancient Egyptian civilization. Research reveals a major shift in the Nile around four thousand years ago, after which the floodplain in the Nile Valley around Luxor greatly expanded.
Drugs.com
JUNE 3, 2024
MONDAY, June 3, 2024 -- Ozempic and Wegovy might help lower the risk of pancreatitis in patients with obesity and type 2 diabetes, a new study says.Up to now, doctors have been cautious about prescribing semaglutide to patients with a history of.
Science Daily: Pharmacology News
JUNE 3, 2024
Researchers develop a vastly more productive way to convert carbon dioxide into useful materials and compounds.
Drugs.com
JUNE 3, 2024
MONDAY, June 3, 2024 -- Nerve surgery can reduce the number of headache days for people who suffer frequent migraines, a new review finds.The procedure also can decrease the frequency and intensity of migraine attacks, according to results.
BioPharma Drive: Drug Pricing
JUNE 3, 2024
The alliance hands Lilly an RNA-based therapy in preclinical testing for ALS and frontotemporal dementia, and includes a research collaboration to develop other, similar medicines.
Drugs.com
JUNE 3, 2024
MONDAY, June 3, 2024 -- Ozempic and Wegovy appear to improve people’s sensitivity to tastes, potentially lowering their desire for sweets, a new study suggests.The active ingredient in the weight-loss medications, semaglutide, also appears to a.
Science Daily: Pharmacology News
JUNE 3, 2024
New research has found evidence that fresh water on Earth, which is essential for life, appeared about four billion years ago -- five hundred million years earlier than previously thought.
Drugs.com
JUNE 3, 2024
MONDAY, June 3, 2024 -- There's potential good news for a sizable minority of people battling advanced colon cancer.Doctors in Britain say that an immunotherapy drug, given before surgery, can help many more patients with a specific genetic profile.
thought leadership
JUNE 3, 2024
Regulatory requirements are a formidable challenge for early stage biotechs and top pharma alike. As health authorities continually revise guidelines across diverse markets, companies are tasked with swift adaption to changing regulations. The cost of non-compliance is high: recalls and sanctions may gravely harm a company’s reputation, especially in an industry where patient trust is paramount.
Drugs.com
JUNE 3, 2024
MONDAY, June 3, 2024 -- People who feel lonely and socially isolated might benefit from more sleep, especially if they’re a young adult, a new study suggests.Better sleep is associated with significantly less emotional and social loneliness, r.
BioPharma Drive: Drug Pricing
JUNE 3, 2024
AstraZeneca’s targeted therapy could see wider use after ASCO data. Elsewhere, Caribou sought to course correct and Lilly talked up its next cancer drug.
The Premier Consulting Blog
JUNE 3, 2024
Author: William Bainbridge A Target Product Profile (TPP) serves as the primary strategic framework that aligns commercial and clinical workstreams. When properly defined, the TPP enables drug developers to manage the development equation of risk x cost x time = success, and it starts by keeping the end in mind. Defining the needs of patients, physicians, and payers early in the process ensures a commercially viable product with a potentially higher valuation.
BioPharma Drive: Drug Pricing
JUNE 3, 2024
With new modalities such as gene and cell therapies, RNA therapeutics, complex biologics and more, today’s science brings unprecedented opportunities to address diseases that have long remained out of reach.
NIOSH Science Blog: Drugs
JUNE 3, 2024
Nanotechnology as we know it today did not exist at the time of the Occupational Safety and Health Act of 1970. Yet, its provisions to “assure safe and healthful working conditions” apply to nanotechnology workplaces and other workplaces where engineered nanomaterials are produced or used. Engineered nanomaterials are used in a variety of products and applications, including in energy, electronics, transportation, environmental remediation, and medicine.
Drug Target Review
JUNE 3, 2024
How does COUR Pharmaceuticals’ immune-modifying nanoparticle platform differ from traditional approaches to treating immune-mediated diseases? Most traditional approaches for treating autoimmune and inflammatory diseases treat the inflammatory mediator by trying to either remove or suppress it, for example removal of B cells non-specifically or killing T cells non-specifically that ultimately lead to broad immunosuppression.
Drug Patent Watch
JUNE 3, 2024
Brivaracetam is the generic ingredient in two branded drugs marketed by Ucb Inc, Aurobindo Pharma Ltd, Lupin Ltd, Sunshine, and Zydus Pharms and, and is included in seven NDAs.
Fierce BioTech
JUNE 3, 2024
Enhancing Adjudication Quality Monitoring Learn about leveraging AI, LLMs, and SA for improved adjudication in oncology trials. Discover transformative potential, ChatGPT's role, and innovative strategies. Enhance data accuracy and patient outcomes. Access now for insights. dfarris Mon, 06/03/2024 - 13:16 Learn about leveraging AI, LLMs, and SA for improved adjudication in oncology trials.
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