Sun.Jul 30, 2023

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Neuroprotective potential of saroglitazar in 6?OHDA induced Parkinson's disease in rats

Chemical Biology and Drug Design

SG restored striatal histopathological damage and dopamine concentration in rat striatum, and behavioural alterations in rats. Thus, SG proved neuroprotective effects in rat model of PD. Abstract Parkinson's disease (PD) is a neurodegenerative disorder that affects 2%–3% of the population worldwide. Clinical presentation of PD includes motor and non-motor symptoms.

Disease 100
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Novel vaccine may hold key to prevent or reduce the impact of Alzheimer’s disease

SCIENMAG: Medicine & Health

Research Highlights: A novel vaccine that targets a protein involved in Alzheimer’s disease helped eliminate toxic cells in mice with the condition. After vaccination, the mice had fewer amyloid plaques and less inflammation in brain tissue and showed improvement in behavior and awareness. Embargoed until 12 p.m. CT/1 p.m.

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New patent expiration for Astrazeneca Ab drug QTERNMET XR

Drug Patent Watch

Annual Drug Patent Expirations for QTERNMET+XR Qternmet Xr is a drug marketed by Astrazeneca Ab and is included in one NDA. There are seven patents protecting this drug. Drug patent… The post New patent expiration for Astrazeneca Ab drug QTERNMET XR appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
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Oxycodone prescriptions after delivery not linked to longer-term opioid use compared to codeine prescriptions

SCIENMAG: Medicine & Health

Postpartum prescriptions for oxycodone were not associated with increased risk of longer-term opioid use compared to codeine prescriptions, according to new research published in CMAJ (Canadian Medical Association Journal) [link] Over the last 10 years, there has been a shift to fewer codeine prescriptions and an increase in prescriptions for stronger opioids, such as hydrocodone, […]

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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New patent expiration for Astrazeneca Ab drug ONGLYZA

Drug Patent Watch

Annual Drug Patent Expirations for ONGLYZA Onglyza is a drug marketed by Astrazeneca Ab and is included in one NDA. It is available from two suppliers. There are two patents… The post New patent expiration for Astrazeneca Ab drug ONGLYZA appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
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LTSC2022 images for XM Cloud are available

Perficient: Drug Development

It somehow passed silent, but XM Cloud now also has ltsc2022 images which will also allow you running you local XM Cloud development in a Process isolation mode on Windows 11. I was routinely poking XM Cloud starterkit codebase, once came across a new parameter introduced within Init.ps1 script: [Parameter(Mandatory = $false, HelpMessage = "Specifies os version of the base image.

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Building Traefik images with ltsc2022 for your Sitecore deployments

Perficient: Drug Development

Since recent you can benefit from Sitecore providing ltsc2022 images for your XM/XP solutions which I previously covered in a seperate article. However, looking at your cluster you may see not all the images are ltsc2022 compatible – there is a 1809-based Traefik image, which is coming separately outside of Sitecore docker registry. Now, it’s good time to get rid of that only left 1809-based Traefik image.

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New patent expiration for Astrazeneca Ab drug KOMBIGLYZE XR

Drug Patent Watch

Annual Drug Patent Expirations for KOMBIGLYZE+XR Kombiglyze Xr is a drug marketed by Astrazeneca Ab and is included in one NDA. It is available from one supplier. There are three… The post New patent expiration for Astrazeneca Ab drug KOMBIGLYZE XR appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
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Ouch! You Injured a Nail: Tips on Best Treatment

Drugs.com

SUNDAY, July 30, 2023 -- If you've ever slammed a door on your finger, you know how badly an injured nail feels, but do you know how to treat one? First, do what you can to prevent one. "To prevent a nail injury, I tell my patients to keep their.

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New patent expiration for Astrazeneca Ab drug QTERN

Drug Patent Watch

Annual Drug Patent Expirations for QTERN Qtern is a drug marketed by Astrazeneca Ab and is included in two NDAs. It is available from one supplier. There are nine patents… The post New patent expiration for Astrazeneca Ab drug QTERN appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Mounjaro, Orforglipron, and CagriSema Line Up to Challenge Ozempic, Wegovy for Weight Loss

Drugs.com

SUNDAY July 30, 2023 -- After drugmaker Novo Nordisk tweaked its diabetes drug Ozempic into Wegovy — a formulation expressly designed to help users shed pounds — sales of both drugs skyrocketed.

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Drug Patent Expirations for the Week of July 30, 2023

Drug Patent Watch

DEXILANT SOLUTAB (dexlansoprazole) Takeda pharms usa Patent: 6,664,276 Expiration: Jul 30, 2023 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact… The post Drug Patent Expirations for the Week of July 30, 2023 appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
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Which pharmaceutical drugs have the most drug patents in Croatia?

Drug Patent Watch

This chart shows the drugs with the most patents in Croatia. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.… The post Which pharmaceutical drugs have the most drug patents in Croatia? appeared first on DrugPatentWatch - Make Better Decisions.