Sat.Jun 29, 2024

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Tips to Safely Helping Your Baby Through Teething Pain

Drugs.com

SATURDAY, June 29, 2024 -- Tending to a teething baby is tough: Parents want to help, but might not be sure how.Teething typically begins around 4 to 7 months of age, as the 20 or so "baby teeth" that will emerge by the age of 3 begin to form. The.

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Design of a covalent protein-protein interaction inhibitor of SRPKs to suppress angiogenesis and invasion of cancer cells

Covalent Modifiers

Cai, G., Bao, Y., Li, Q. et al. Commun Chem 7 , 144 (2024). [link] Serine–arginine (SR) proteins are splicing factors that play essential roles in both constitutive and alternative pre-mRNA splicing. Phosphorylation of their C-terminal RS domains by SR protein kinases (SRPKs) regulates their localization and diverse cellular activities. Dysregulation of phosphorylation has been implicated in many human diseases, including cancers.

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DrugPatentWatch Week in Review

Drug Patent Watch

Patent Expirations and Generic Competition This week saw several major blockbuster drugs facing patent expirations, potentially opening the market for […] Source

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RETURN TO ARTICLES ASAPPREVARTICLENEXT N-Acyl-N-Alkyl Sulfonamide Probes for Ligand-Directed Covalent Labeling of GPCRs: The Adenosine A2B Receptor as Case Study

Covalent Modifiers

Bert L. H. Beerkens, Vasiliki Andrianopoulou, Xuesong Wang, Rongfang Liu, Gerard J. P. van Westen, Willem Jespers, Adriaan P. IJzerman, Laura H. Heitman, and Daan van der Es ACS Chemical Biology 2024 DOI: 10.1021/acschembio.4c00210 Small molecular tool compounds play an essential role in the study of G protein-coupled receptors (GPCRs). However, tool compounds most often occupy the orthosteric binding site, hampering the study of GPCRs upon ligand binding.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Which pharmaceutical companies have the most drug patents in Australia?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Australia. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.

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Development of a Dual Factor Activatable Covalent Targeted Photoacoustic Imaging Probe for Tumor Imaging

Covalent Modifiers

Jiho Song , Tianqu Zhai , Heung Sik Hahm , Yuancheng Li , Hui Mao , Xueding Wang , Janggun Jo , Jae Won Chang , Angew. Chem. Int. Ed. 2024 , e202410645. [link] Photoacoustic imaging (PAI) is an emerging modality in biomedical imaging with superior imaging depth and specificity. However, PAI still has significant limitations, such as the background noise from endogenous chromophores.

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Navigating Salesforce Record Types: A Beginner’s Guide

Perficient: Drug Development

Hello Trailblazers… In today’s world which is full of innovations and technologies, Salesforce is a powerful customer relationship management (CRM) platform that offers numerous customization options to fit the unique needs of businesses. One of the essential features that allow for such customization is “Record Types.” Record Types in Salesforce enable organizations to manage different business processes, page layouts, and picklist values for various users.

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Understanding Java Enum ConditionType in Katalon Studio. Pt1

Perficient: Drug Development

Introduction Katalon Studio’s ConditionType enum is a key feature that allows testers to define specific criteria for interacting with web elements. This flexibility is crucial for creating robust and reliable automated tests. The ConditionType enum provides a variety of condition types, each serving a unique purpose in the identification and interaction with web elements.

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Understanding Java Enum ConditionType in Katalon Studio. Pt2

Perficient: Drug Development

Introduction In this follow-up blog, we will explore the remaining condition types available in the ConditionType enum. Understanding these additional condition types will further enhance your ability to create robust and flexible test automation scripts in Katalon Studio. Each condition type serves a unique purpose in defining criteria for identifying and interacting with web elements, ensuring the reliability and accuracy of your automated tests.

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