Fri.Jun 14, 2024

article thumbnail

Some CRISPR screens may be missing cancer drug targets

Broad Institute

Some CRISPR screens may be missing cancer drug targets By Allessandra DiCorato June 14, 2024 Breadcrumb Home Some CRISPR screens may be missing cancer drug targets Current CRISPR guides don’t work equally well in cells from people of all ancestries, which could lead to false negative results. By Allessandra DiCorato June 14, 2024 Credit: Ricardo Job-Reese, Broad Communications CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically t

Drugs 145
article thumbnail

Tiny New Zealand bird delivers a lesson in birdsong evolution

Science Daily: Pharmacology News

Scientists are rethinking the evolution of vocal learning in birds. New Zealand's smallest bird, the rifleman or titipounamu, may have a rudimentary version of the talent possessed by parrots, hummingbirds and songbirds.

124
124
article thumbnail

FDA Tells Vaccine Makers to Target New COVID Variant for Fall

Drugs.com

FRIDAY, June 14, 2024 -- COVID vaccine makers will be advised to update their shots to target the KP.2 variant, an offshoot of the JN.1 variant that spread widely last winter, the U.S. Food and Drug Administration announced Thursday. It's a.

Vaccine 115
article thumbnail

Infectious H5N1 influenza virus in raw milk rapidly declines with heat treatment

Science Daily: Pharmacology News

The amount of infectious H5N1 influenza viruses in raw milk rapidly declined with heat treatment in laboratory research. However, small, detectable amounts of infectious virus remained in raw milk samples with high virus levels when treated at 72 degrees Celsius (161.6 degrees Fahrenheit) for 15 seconds -- one of the standard pasteurization methods used by the dairy industry.

Virus 116
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

ADHD Patients Could Face Disrupted Access to Meds Following Fraud Case

Drugs.com

FRIDAY, June 14, 2024 -- The two top officers of a telehealth company that began to distribute ADHD drugs widely during the pandemic have been charged with health care fraud, the U.S. Department of Justice announced Thursday. The arrests will.

Drugs 111
article thumbnail

Sharks have depleted functional diversity compared to the last 66 million years

Science Daily: Pharmacology News

New research has found that sharks retained high levels of functional diversity for most of the last 66 million years, before steadily declining over the last 10 million years to its lowest value in the present day.

More Trending

article thumbnail

High-precision measurements challenge our understanding of Cepheids

Science Daily: Pharmacology News

Scientists have clocked the speed of Cepheid stars -- 'standard candles' that help us measure the size of the universe -- with unprecedented precision, offering exciting new insights about them.

93
article thumbnail

'Good Days and Bad:' Catherine, Princess of Wales, Gives Cancer Update

Drugs.com

FRIDAY, June 14, 2024 -- Catherine, Princess of Wales, has released the first update on her cancer journey since announcing her diagnosis in late March.In a message posted to her Instagram account on Friday, the princess, 42, said that, "I am.

98
article thumbnail

Takeda circles a leukemia drug; J.P. Morgan moves into biotech investing

BioPharma Drive: Drug Pricing

The Japanese pharma paid $100 million to secure option rights to an Ascentage drug. Elsewhere, J.P. Morgan Private Capital closed its first fund and the FDA gave new COVID shot advice.

FDA 67
article thumbnail

Even Temporary Loneliness Can Harm Physical Health

Drugs.com

THURSDAY, June 14, 2024 -- You don't consider yourself a lonely person generally, but sometimes have days where feelings of loneliness set in. If you're one of those people, even that transient loss of connection with others could be impacting your.

98
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Radiopharma drugmaker Telix pulls US IPO plans

BioPharma Drive: Drug Pricing

The Australia-based company had proposed raising $202 million via an initial stock sale, but withdrew its filing, citing its shares’ recent price appreciation on Australia’s stock exchange.

67
article thumbnail

Just 1 in 20 Animal Studies Yield Treatments That Make it to Humans

Drugs.com

FRIDAY, June 14, 2024 -- Animal studies are often considered a first step in finding new drugs and treatments for human diseases, but a new review has discovered that precious few actually produce real-world therapies. Only 5% of therapies tested.

article thumbnail

Which pharmaceutical drugs have the most drug patents in Bulgaria?

Drug Patent Watch

This chart shows the drugs with the most patents in Bulgaria. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.

Drugs 59
article thumbnail

GLP-1 Meds May Help Extremely Obese Qualify for Weight-Loss Surgery

Drugs.com

FRIDAY, June 14, 2024 -- Taking a cutting-edge weight-loss drug could help extremely obese patients drop enough pounds to be eligible for bariatric surgery, a new study shows. Patients with extreme obesity -- a BMI of 70 or more -- are at higher.

Drugs 98
article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

How AI Accelerates Clinical & Drug Development Timelines

Fierce BioTech

How AI Accelerates Clinical & Drug Development Timelines pesurya Fri, 06/14/2024 - 10:59 Wed, 09/11/2024 - 14:00 Resource Type Webinar Viswa Colluru, Ph.D. Tony Cardozo Todd Rudo, M.D. Beth Williams Duration 60 Minutes As the drug development landscape rapidly evolves, artificial intelligence (AI) is emerging as a transformative force, fundamentally reshaping processes and enhancing efficiencies.

article thumbnail

New Form of Psychotherapy Might Help Ease Chronic Pain

Drugs.com

FRIDAY, June 14, 2024 -- A new form of psychotherapy appears to work even better at treating chronic pain in older adults than gold-standard cognitive behavioral therapy (CBT), a new study finds. U.S. veterans who received emotional awareness and.

article thumbnail

3 PIM Analytics Tools to Drive More Sales

Perficient: Drug Development

Importance of Product Data in Driving Sales When you don’t have a storefront and a salesperson to do the talking, your product content has to be rich. So, your task is to reduce the uncertainty as much as possible. Remember, customers won’t always buy the better product; they prefer the product they better understand and can find. PIM Analytics can be important tool in your toolkit to make sure your product content is working as intended.

article thumbnail

Dolphins Off Florida, Georgia Have High Levels of Mercury

Drugs.com

THURSDAY, June 14, 2024 -- Dolphins living off the coasts of Georgia and Florida have elevated levels of mercury in their bodies, new research shows. That could have implications for people, said a team led by Colleen Bryan, a research biologist at.

article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

How Spatial Omics Is Unleashing the Potential of Regenerative Medicine

Fierce BioTech

How Spatial Omics Is Unleashing the Potential of Regenerative Medicine Spatial omics, the study of molecular profiles within their spatial context, is revolutionizing regenerative medicine by offering insights into tissue organization and disease pathology. Download this free whitepaper today which addresses why spatial omics is a key enabler of research that could transform lives. smarcus Fri, 06/14/2024 - 11:48 Spatial omics, the study of molecular profiles within their spatial context, is rev

Disease 52
article thumbnail

Loaded, Unlocked Guns Common in American Homes, Study Finds

Drugs.com

FRIDAY, June 14, 2024 -- In half of American homes containing a loaded gun, that gun is kept unsecured and ready for potential use, often with children in the home, new research shows. The finding is especially troubling given the link between gun.

article thumbnail

Usability and Experience (UX) in Universal Design Series: Impact on Diverse User Groups – 5

Perficient: Drug Development

Embracing Diversity: The Impact of Usability and UX on Diverse User Groups In this installment of our Usability and Experience (UX) in Universal Design series, we will explore the profound impact that usability and UX principles have on diverse user groups. Universal Design aims to create products, environments, and systems that are accessible and inclusive for everyone, regardless of their abilities, age, cultural background, or cognitive differences.

article thumbnail

Animal Studies Suggest New Treatment Target for Spinal Cord Injury

Drugs.com

FRIDAY, June 14, 2024 -- Spinal cord injuries can cause the body to go haywire, with misfiring nerves causing dangerous “fight-or-flight” responses. This makes typical and normally harmless problems like having a full bladder prompt.

article thumbnail

AbbVie joins in latest gastrointestinal drug chase

BioPharma Drive: Drug Pricing

Following Roche, Merck and others into a hot field, the Humira maker will pay $150 million to license a preclinical TL1A antibody for IBD.

article thumbnail

Swimming 'Microbots' Could Speed Meds to Lung Tumors, Early Study Suggests

Drugs.com

FRIDAY, June 14, 2024 -- Scientists have developed microscopic robots capable of swimming through the lungs to deliver chemotherapy directly to lung cancer cells. In early testing, these microbots extended the average survival time of lab mice.

94
article thumbnail

Getting to the Heart of Science with Sophie Dubois

Alta Sciences

Getting to the Heart of Science with Sophie Dubois blussier Fri, 06/14/2024 - 21:16 HTML The Stories That Inspire In this video, our very own Sophie Dubois shares what led her to Altasciences and how the company’s core values and mission of helping to improve lives resonate with her. Image Getting_to_the_Heart_of_Science_With_Sophie_Dubois.

Science 40
article thumbnail

The Regulatory Binder Checklist For Clinical Trial Sites

Advarra

A regulatory binder is essential for managing clinical trial documents, ensuring regulatory compliance, and facilitating audits. It organizes critical documents; provides easy access for trial monitors, auditors, and regulatory authorities; and serves as a reference for the research team. Though not legally binding, maintaining a regulatory binder is highly recommended for all intervention trials.