BioPharma Drive: Drug Pricing
DECEMBER 20, 2023
The Healey center is at the front of ALS research and care, earning acclaim from patients, doctors and scientists. Still, the complexities of the disease and of drug development have brought hard-felt losses.
Chemical Biology and Drug Design
DECEMBER 20, 2023
Triptolide can effectively inhibit proliferation and invasion as well as promote apoptosis of HT29 cells. Its mechanism of action may be related to the inhibition of Nrf2 signaling. As such, triptolide is expected to be a potential drug for colorectal cancer treatment. Abstract Triptolide (TPL), the main active ingredient of Tripterygium wilfordii , has anti-inflammatory, immunomodulatory, and antitumor actions.
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Science Daily: Pharmacology News
DECEMBER 20, 2023
The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.
Broad Institute
DECEMBER 20, 2023
With AI, researchers identify a new class of antibiotic candidates By Tom Ulrich December 20, 2023 Breadcrumb Home With AI, researchers identify a new class of antibiotic candidates New compounds can kill methicillin-resistant Staphylococcus aureus (MRSA), an often-lethal bacterial pathogen By Anne Trafton, MIT News Office December 20, 2023 Methicillin-resistant Staphylococcus aureus (gold) on the remains of an immune cell (red) Related people James Collins Related programs Infectious Disease an
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
DECEMBER 20, 2023
Conventional wisdom suggests that searching online to evaluate the veracity of misinformation would reduce belief in it. But a new study by a team of researchers shows the opposite occurs: Searching to evaluate the truthfulness of false news articles actually increases the probability of believing misinformation.
Drugs.com
DECEMBER 20, 2023
WEDNESDAY, Dec. 20, 2023 -- The new COVID variant known as JN.1 was named a "variant of interest" by the World Health Organization on Tuesday, which means health officials are now closely tracking its rapid spread across the globe.So far, the.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
DECEMBER 20, 2023
WEDNESDAY, Dec. 20, 2023 -- Women struggling with fertility and using in vitro fertilization (IVF) to conceive sometimes turn to supplements for help.Unfortunately, a new study finds only weak evidence to support that strategy.
Science Daily: Pharmacology News
DECEMBER 20, 2023
An artificial intelligence-driven system has autonomously learned about certain Nobel Prize-winning chemical reactions and designed a successful laboratory procedure to make them. The AI did so in just a few minutes and correctly on its first attempt. According to the authors, this is the first time that a non-organic intelligence planned, designed and executed this complex reaction that was invented by humans.
Drugs.com
DECEMBER 20, 2023
WEDNESDAY, Dec. 20, 2023 -- Beyond a myriad of other consequences, childhood trauma appears to raise the specter of chronic pain in adulthood, new research shows.Researchers pored over 75 years' worth of data involving more than 826,000 people.
SCIENMAG: Medicine & Health
DECEMBER 20, 2023
A new study from Lawson Health Research Institute and Western University published in the journal Microbiome has found changes in the microbiome in multiple locations in the body are linked to the formation of kidney stones.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
DECEMBER 20, 2023
WEDNESDAY, Dec. 20, 2023 -- Many patients with advanced colon cancers who are successfully treated with immunotherapy and then stop those treatments appear to face little risk of tumor progression two years later.That's the main finding from a.
Science Daily: Pharmacology News
DECEMBER 20, 2023
Researchers develop transistor that simultaneously processes and stores information like the human brain. Transistor goes beyond categorization tasks to perform associative learning. Transistor identified similar patterns, even when given imperfect input. Previous similar devices could only operate at cryogenic temperatures; new transistor operates at room temperature, making it more practical.
Drugs.com
DECEMBER 20, 2023
WEDNESDAY, Dec. 20, 2023 — Warmer weather linked to climate change is likely to cause rampaging clouds of mosquitos in the future, a new study forecasts.Rising temperatures can make it tougher for the predators that feast on mosquito larvae to.
Science Daily: Pharmacology News
DECEMBER 20, 2023
A research team has uncovered a previously undetected mechanism in mice -- starring the genetic molecule RNA -- that could explain how each sensory cell, or neuron, in mammalian noses becomes tailored to detect a specific odor chemical.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
DECEMBER 20, 2023
WEDNESDAY, Dec. 20, 2023 -- Anxiety, depression and post-traumatic stress are common among people caring for the victim of a recent stroke, a new study has found.Nearly 30% of caregivers of severe stroke patients experience stress and emotional.
Conversations in Drug Development Trends
DECEMBER 20, 2023
In November 2023, at Outsourcing Clinical Trials Dach in Zurich, our Executive Director, Oncology Strategy Lead, Matt Cooper , presented “Delivering Oncology Studies – Challenges and Considerations.” His presentation covered various aspects of oncology clinical programs, focusing on study design trends, with reference to both the recently implemented FDA Project Optimus guidance and studies we have seen from sponsors.
Drugs.com
DECEMBER 20, 2023
WEDNESDAY, Dec. 20, 2023 -- Early research in mice could be getting closer to the roots of what causes Parkinson's disease.A "pathological" form of a common brain protein, alpha-synuclein, could play a role in the death of dopamine-rich brain.
Science Daily: Pharmacology News
DECEMBER 20, 2023
Using artificial intelligence, researchers discovered a class of compounds that can kill methicillin-resistant Staphylococcus aureus (MRSA), a drug-resistant bacterium that causes more than 10,000 deaths in the U.S. each year.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
DECEMBER 20, 2023
WEDNESDAY, Dec. 20, 2023 -- Long left to the fringes of the recreational drug culture, psilocybin -- the hallucinatory ingredient in "magic mushrooms" — has recently been making inroads as a legitimate (and fast-acting) antidepressant.Research.
SCIENMAG: Medicine & Health
DECEMBER 20, 2023
Having high cholesterol and high blood pressure before the age of 55 has a lasting impact on your risk of heart disease in later life – even if you subsequently lower your levels Credit: geralt, Pixabay, CC0 ([link] Having high cholesterol and high blood pressure before the age of 55 has a lasting impact on […]
Drugs.com
DECEMBER 20, 2023
WEDNESDAY, Dec. 20, 2023 — What's even more nerve-wracking than paying taxes?The holidays, according to a majority of Americans, who say it takes them weeks to recover from seasonal stress. "The holidays are an easy time to justify putting.
SCIENMAG: Medicine & Health
DECEMBER 20, 2023
UTICA, N.Y. – Jason R. McCarthy, Ph.D., associate professor of biomedical research and translational medicine and scientific operations director at MMRI, recently published an innovative manuscript titled, Biomimetic Nanomaterials for the Immunomodulation of the Cardiosplenic Axis Post-Myocardial Infarction.
Science Daily: Pharmacology News
DECEMBER 20, 2023
Researchers have identified a species of frog new to science. The Indonesian amphibian is the size of a quarter, unlike its two-pound cousins, and has tiny fangs. Nearly uniquely among amphibians, they lay their eggs on the leaves of trees, and the males guard and tend to the nests.
Cytel
DECEMBER 20, 2023
Perspectives covers a wide range of topics related to real-world evidence and real-world data, from overcoming health inequalities in product development to the use of externally controlled trials to the expanding role of artificial intelligence, and much more.
Science Daily: Pharmacology News
DECEMBER 20, 2023
Supercomputer helped astronomers develop PRIYA, the largest suite of hydrodynamic simulations yet made of large-scale structure in the universe.
BioPharma Drive: Drug Pricing
DECEMBER 20, 2023
The Dutch biotech’s star product has lost some luster after a second failed Phase 3 trial in two months, this time for a skin condition called pemphigus.
sptlabtech
DECEMBER 20, 2023
As we reflect on another year, we invite you to join us in anticipating more innovations in 2024. Stay tuned for further updates and announcements from SPT Labtech, as we continue to empower the scientific community with our cutting-edge automated solutions. Stay Curious, Stay Innovated.
Drug Patent Watch
DECEMBER 20, 2023
This chart shows the pharmaceutical companies with the most patents in Cyprus. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is… The post Which pharmaceutical companies have the most drug patents in Cyprus? appeared first on DrugPatentWatch - Make Better Decisions.
Covalent Modifiers
DECEMBER 20, 2023
Ka Yang,Rebecca L. Whitehouse,Shane L. Dawson,Lu Zhang,Jeffrey G. Martin,Douglas S. Johnson,Joao A. Paulo,Steven P. Gygi,Qing Yu Cell Chemical Biology 2023 DOI: [link] Chemoproteomics has made significant progress in investigating small-molecule-protein interactions. However, the proteome-wide profiling of cysteine ligandability remains challenging to adapt for high-throughput applications, primarily due to a lack of platforms capable of achieving the desired depth using low input in 96- or 384-
Drug Patent Watch
DECEMBER 20, 2023
Annual Drug Patent Expirations for BENDEKA Bendeka is a drug marketed by Eagle Pharms and is included in one NDA. It is available from one supplier. There are sixteen patents… The post New patent for Eagle Pharms drug BENDEKA appeared first on DrugPatentWatch - Make Better Decisions.
Covalent Modifiers
DECEMBER 20, 2023
Hartmann, P., Bohdan, K., Hommrich, M. et al. Nat. Chem. 2023 [link] Cysteine conjugation is an important tool in protein research and relies on fast, mild and chemoselective reactions. Cysteinyl thiols can either be modified with prefunctionalized electrophiles, or converted into electrophiles themselves for functionalization with selected nucleophiles in an independent step.
Drug Patent Watch
DECEMBER 20, 2023
Icosapent ethyl is the generic ingredient in two branded drugs marketed by Apotex, Dr Reddys, Hikma, Strides Pharma, Teva Pharms Usa, Zydus, and Amarin Pharms and, and is included in… The post New tentative approval for Ascent Pharms drug icosapent ethyl appeared first on DrugPatentWatch - Make Better Decisions.
Drugs.com
DECEMBER 20, 2023
WEDNESDAY, Dec. 20, 2023 -- Exposure to a common chemical group found in many household products may delay or even prevent a woman from becoming pregnant, a new study says.Phthalates can lower a woman’s odds of becoming pregnant by up to 18% in.
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