Mon.Jun 24, 2024

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Myths about intermittent fasting, debunked

Science Daily: Pharmacology News

Research shows that the increasingly popular weight-loss strategy is safe. Intermittent fasting has become an increasingly popular way to lose weight without counting calories. And a large body of research has shown it s safe. Still, several myths about fasting have gained traction.

Research 328
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Twice-a-Year Injection Gives Women Full Protection Against HIV, Trial Finds

Drugs.com

MONDAY, June 24, 2024 -- Just two injections a year of a new HIV drug protected young women in Africa from infection with the sexually transmitted disease, new trial results show.In announcing the findings, Gilead Sciences Inc. said its HIV.

Trials 279
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Carbon dioxide's heavy stamp on temperature: Doubling CO2 may mean 7 to 14 degree increase

Science Daily: Pharmacology News

A doubling of the amount of CO2 in the atmosphere could cause an increase in the average temperature on earth from 7 to even a maximum of 14 degrees. That is shown in the analysis of sediments from the Pacific Ocean off the coast of California.

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FDA's Move to OK First Menthol Vapes Is Big Mistake, Health Advocates Say

Drugs.com

MONDAY, June 24, 2024 -- The U.S. Food and Drug Administration's decision to authorize the first menthol-flavored e-cigarettes has drawn the the ire of health advocates who say the decision undermines efforts to end the youth vaping epidemic in.

FDA 264
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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New study confirms forever chemicals are absorbed through human skin

Science Daily: Pharmacology News

A study of 17 commonly used synthetic 'forever chemicals' has shown that these toxic substances can readily be absorbed through human skin.

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Facial recognition linked to close social bonds, not social butterflies

Science Daily: Pharmacology News

Do you have trouble recognizing faces, or do you never forget a face? The better you are at facial recognition, the more supportive relationships you are likely to have, regardless of your personality type.

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Timing of Chemo Could Be Key to Pancreatic Cancer Outcomes

Drugs.com

MONDAY, June 24, 2024 -- Giving people with pancreatic cancer chemotherapy both before and after a tumor-removing surgery brought better outcomes than if they got the drugs only after the surgery, new research shows.Researchers at the Yale Cancer.

Research 246
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Star clusters observed within a galaxy in the early Universe

Science Daily: Pharmacology News

The history of how stars and galaxies came to be and evolved into the present day remains among the most challenging astrophysical questions to solve yet, but new research brings us closer to understanding it. New insights about young galaxies during the Epoch of Reionization have been revealed. Observations with the James Webb Space Telescope (JWST) of the galaxy Cosmic Gems arc (SPT0615-JD) have confirmed that the light of the galaxy was emitted 460 million years after the big bang.

Research 300
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Anti- Seizure Meds Are Crucial, But Can Trigger Severe Reactions

Drugs.com

MONDAY, June 24, 2024 -- Specific steps can be taken to reduce the risk of potentially fatal reactions to anti-seizure medications, researchers report in a new review.Performing blood tests, asking patients about risk factors and modifying dosages.

Research 246
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Researchers develop RNA-targeting technology for precisely manipulating parts of human genes

Science Daily: Pharmacology News

Researchers have harnessed a bacterial immune defense system, known as CRISPR, to efficiently and precisely control the process of RNA splicing. The technology opens the door to new applications, including systematically interrogating the functions of parts of genes and correcting splicing deficiencies that underlie numerous diseases and disorders.

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Older Americans in Senior Housing Have Better Health Than Those Living at Home

Drugs.com

MONDAY, June 21, 2024 -- Independent living is important for seniors, but a new study shows it might not be the best thing for their health.Older adults living in senior housing tended to have better health than those who remain in their own homes.

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A hidden treasure in the Milky Way -- Astronomers uncover ultrabright x-ray source

Science Daily: Pharmacology News

Astronomers uncovered that a well-known X-ray binary, whose exact nature has been a mystery to scientists until now, is actually a hidden ultraluminous X-ray source.

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Inhaled Insulin Could Help Folks With Type 1 Diabetes Avoid Needles

Drugs.com

MONDAY, June 24, 2024 -- Inhaled insulin could be a better option than injections or pumps for some patients with type 1 diabetes, a new clinical trial shows.Patients using inhaled insulin (Afrezza) plus long-lasting insulin degludec injections had.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Geologists expect Chang'e-6 lunar surface samples to contain volcanic rock and impact ejecta

Science Daily: Pharmacology News

On June 25, China's Chang'e-6 (CE-6) lunar probe is set to return to Earth, carrying the first surface samples collected from the farside of the Moon. In anticipation of this historic event, scientists are publishing their predictions for the unique materials that may be found in the CE-6 samples.

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U.S. Supreme Court Agrees to Hear Case on Medical Care for Transgender Youth

Drugs.com

MONDAY, June 24, 2024 -- The U.S. Supreme Court announced Monday that it would hear a case on a Tennessee law that bans transgender minors from receiving certain medical treatments in that state.The banned treatments include puberty-blocking drugs.

Treatment 239
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Obesity drugs from Altimmune, Hengrui show potential; Lilly details Zepbound sleep apnea data

BioPharma Drive: Drug Pricing

The American Diabetes Association’s annual meeting provided a forum for early trial results on several would-be weight loss drug competitors.

Drugs 148
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Covalent Modifiers - Untitled Article

Covalent Modifiers

Nickolas J. Serniuck, Eden Kapcan, Duane Moogk, Allyson E. Moore, Benjamin P.M. Lake, Galina Denisova, Joanne A. Hammill, Jonathan L. Bramson, Anthony F. Rullo, Molecular Therapy: Oncology , 2024 , 200842, [link] Proximity-induction of cell-cell interactions via small molecules represents an emerging field in basic and translational sciences. Covalent anchoring of these small molecules represents a useful chemical strategy to enforce proximity, however it remains largely unexplored for driving c

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Novo fills in positive picture for preventive hemophilia drug

BioPharma Drive: Drug Pricing

Phase 3 trial results should support an approval application for the drug, which analysts view as a potential competitor to Roche’s blockbuster medicine Hemlibra.

Drugs 148
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Rates of Distress, Depression Have Doubled Among Transgender Americans Since 2014

Drugs.com

MONDAY, June 24, 2024 -- The rate of self-reported mental distress and depression among American adults who identify as transgender or gender-diverse (TGD) has more than doubled between 2014 and 2022, an analysis of federal health data.

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Bridging science and humanity: Systems thinking in clinical trial design

BioPharma Drive: Drug Pricing

Benefits of adopting the systems thinking approach in clinical trial design.

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Why Are Brain Tumors More Deadly for Kids in Poorer Neighborhoods?

Drugs.com

MONDAY, June 24, 2024 -- U.S. children with inoperable brain tumors appear to die sooner and find it harder to get care if they live in poorer neighborhoods, a new study finds.Children from higher-income areas had more than double the average.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Alnylam says heart drug succeeds in closely watched study

BioPharma Drive: Drug Pricing

Positive results from a Phase 3 trial of vutrisiran in transthyretin amyloidosis cardiomyopathy come eight months after the FDA rejected another medicine Alnylam developed for the condition.

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'A Pretty Cool Experience:' Having a Kidney Transplant While Awake

Drugs.com

MONDAY, June 24, 2024 -- John Nicolas was deep into kidney transplant surgery when he decided to ask his doctors if they’d started yet.“At one point during surgery, I recall asking, ‘Should I be expecting the spinal anesthesia to kick in?’” Nicolas.

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The role of a specialty pharmacy in enhancing patient access to rare and gene therapies

BioPharma Drive: Drug Pricing

Four critical components in which the right specialty pharmacy partner can bring rare and gene therapy manufacturers the scale, expertise and capabilities needed to drive enhanced patient access.

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Leveraging 505(b)(2) to Innovate Beyond Existing Drug Patents

Drug Patent Watch

The 505(b)(2) regulatory pathway provides an attractive avenue for drug developers to bring new products to market by leveraging existing data on approved drugs. This pathway allows modifications and improvements to be made to existing drugs, while potentially reducing development costs and timelines compared to the traditional new drug application (NDA) route.

Drugs 105
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The Next Generation of Vaccine Mega Trials

PPD

In the realm of vaccine development, mega trials — studies enrolling 5,000 subjects or more — have been instrumental in the fight against many pathogens, including influenza, rotavirus, malaria, RSV and most recently in the rapid development of vaccines against COVID-19. The landscape of these trials is evolving, influenced by technological advancements, changing industry standards and innovative clinical trial designs.

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