Thu.Jan 18, 2024

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Treatment potential for immunotherapy-induced cytokine release syndrome  

Drug Discovery World

Poolbeg Pharma, a biopharmaceutical company focused on the development and commercialisation of medicines targeting diseases with a high unmet medical need, has announced promising in vivo results for POLB 001 in addressing cancer immunotherapy-induced cytokine release syndrome (CRS). POLB 001 demonstrated efficacy in reducing cancer immunotherapy-induced CRS in an in vivo animal model with CRS symptoms significantly improved following administration of POLB 001.

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Study Links Use of Acetaminophen in Pregnancy With Child Behavioral Issues

Drugs.com

THURSDAY, Jan. 18, 2024 -- Expecting moms who often turn to acetaminophen for their aches and pains are more likely to wind up with kids who have behavioral issues, a new study warns.Children between the ages of 2 and 4 were more likely to have.

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New podcast: Why is Europe a drug discovery epicentre?

Drug Discovery World

This is the latest episode of the free DDW narrated podcast, titled “Revolutionary technology for drug discovery and development” which covers three written for Volume 23 – Issue 4, Fall 2022 of DDW. They are called: European drug discovery and development success stories , Basel: A centre for ground-breaking oncology , and On the European CGT landscape, zebras and the future of medicine.

Therapies 148
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Self-powered sensor automatically harvests magnetic energy

Science Daily: Pharmacology News

Researchers have designed a self-powering, battery-free, energy-harvesting sensor. Using the framework they developed, they produced a temperature sensor that can harvest and store the energy from the magnetic field that exists in the open air around a wire.

Research 124
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Why is Europe a drug discovery epicentre?

Drug Discovery World

This is the latest episode of the free DDW narrated podcast, titled “Revolutionary technology for drug discovery and development” which covers three written for Volume 23 – Issue 4, Fall 2022 of DDW. They are called: European drug discovery and development success stories , Basel: A centre for ground-breaking oncology , and On the European CGT landscape, zebras and the future of medicine.

Drugs 130
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Daily Multivitamin Might Help Aging Brains

Drugs.com

THURSDAY, Jan. 18, 2024 -- A daily multivitamin could help people keep their brains healthy as they age, a new trial finds.Results suggest taking multivitamins could help prevent memory loss and slow cognitive aging among older adults, researchers.

Trials 116

More Trending

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Sea otters helped prevent widespread California kelp forest declines over the past century

Science Daily: Pharmacology News

The study reveals dramatic regional kelp canopy changes along the California coast over a 100-year period. During this time there was a significant increase in kelp forest canopy along the central coast, the only region of California where southern sea otters survived after being hunted nearly to extinction for their fur in the 1800s. Contrastingly, kelp canopy decreased in northern and southern regions.

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FDA Approves AI Device That Helps Spot Skin Cancer

Drugs.com

THURSDAY, Jan. 18, 2024 (HealthDay news) -- The first medical device powered by artificial intelligence and designed to help doctors catch skin cancer has been approved by the U.S. Food and Drug Administration.Although not meant to be used as a.

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Researchers create faster and cheaper way to print tiny metal structures with light

Science Daily: Pharmacology News

Researchers have developed a light-based means of printing nano-sized metal structures that is 480 times faster and 35 times cheaper than the current conventional method. It is a scalable solution that could transform a scientific field long reliant on technologies that are prohibitively expensive and slow. Their method is called superluminescent light projection (SLP).

Research 114
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Bayer signals ‘significant’ layoffs in plan to shrink bureaucracy

BioPharma Drive: Drug Pricing

The company said it has secured agreement from labor representatives in Germany for job cuts that will shed “many managerial employees.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Seniors Who Smoke Weed & Drive Are Road Hazards: Study

Drugs.com

THURSDAY, Jan. 18, 2024 -- Many studies have found that getting high on weed and then getting behind the wheel is dangerous for young drivers, and now new research finds it's no different for seniors. In a driving-simulator experiment, seniors who.

Research 105
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Partner spotlight: Advancing melanoma clinical trials with Melanoma Research Alliance

Antidote

Antidote’s mission is to connect patients with medical research so medical breakthroughs can take place. A key part of our strategy is partnering with nonprofits and patient advocacy groups. We provide our clinical trial matching technology, Antidote Match, at no cost to these organizations, to help patients and caregivers discover new research opportunities and connect to clinical trials quickly and easily.

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Infant Deaths Higher in States Where Abortion is Banned: Report

Drugs.com

THURSDAY, Jan. 18, 2024 -- Abortion bans are intended to preserve the lives of children, proponents say, but a new study has found infants are more likely to die in the states with the most restrictive laws.States with the tightest abortion laws.

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Gene therapy biotech Jaguar spins out manufacturing company

BioPharma Drive: Drug Pricing

Called Advanced Medicine Partners, the new company will offer specialized cell and gene therapy manufacturing services to biotech and pharma clients.

Therapies 113
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Five-Year Survival for Pancreatic Cancer Has Risen to 13%

Drugs.com

THURSDAY, Jan. 18, 2024 -- Pancreatic cancer is known as a 'silent killer' because it's usually only detected in its later stages.But there's a glimmer of good news for patients: The five-year survival rate for people with the disease has crept up.

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Third major study finds evidence that daily multivitamin supplements improve memory and slow cognitive aging in older adults

Science Daily: Pharmacology News

Researchers tested the effects of a daily multivitamin on cognitive changes in a study of 573 participants with in-person visits in the COSMOS trial. The researchers also conducted a meta-analysis among over 5,000 non-overlapping participants across the three separate cognition studies within the COSMOS trial. Results showed a statistically significant benefit for cognition among participants taking the multi-vitamin compared to placebo, suggesting that a multi-vitamin could help prevent memory

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Non-White U.S. Kids Get Worse Pediatric Care

Drugs.com

THURSDAY, Jan. 18, 2024 -- Pediatric care for kids who aren’t white is worse across the United States, a new study finds.Racial inequities for children of color are pervasive, extending from neonatal care, emergency medicine and surgery to.

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Mini-robots modeled on insects may be smallest, lightest, fastest ever developed

Science Daily: Pharmacology News

Two insect-like robots, a mini-bug and a water strider may be the smallest, lightest and fastest fully functional micro-robots ever known to be created. Such miniature robots could someday be used for work in areas such as artificial pollination, search and rescue, environmental monitoring, micro-fabrication or robotic-assisted surgery. Reporting on their work in the proceedings of the IEEE Robotics and Automation Society's International Conference on Intelligent Robots and Systems, the mini-bug

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Norovirus outbreaks are detectable by wastewater monitoring earlier than by other surveillance methods depending on reporting practices, making this a potentially important public health tool

SCIENMAG: Medicine & Health

Norovirus outbreaks are detectable by wastewater monitoring earlier than by other surveillance methods depending on reporting practices, making this a potentially important public health tool. Credit: Ammerman et al, 2024. CC-BY 4.

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Study reveals a universal pattern of brain wave frequencies

Science Daily: Pharmacology News

The six anatomical layers of the mammalian brain cortex show distinct patterns of electrical activity which are consistent throughout the entire cortex and across several animal species, including humans, a study has found.

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Researchers awarded $2.7 million grant to develop the faba bean as a sustainable mid-Atlantic crop

SCIENMAG: Medicine & Health

Consider the faba bean, also known as the fava bean or broad bean. Credit: Photo by Suzanne Pruitt for Virginia Tech. Consider the faba bean, also known as the fava bean or broad bean. The bright-green legume has been enjoyed as a diet staple for thousands of years in Africa, Asia, and the Mediterranean.

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Ancient 'chewing gum' reveals stone age diet

Science Daily: Pharmacology News

What did people eat on the west coast of Scandinavia 10,000 years ago? A new study of the DNA in a chewing gum shows that deer, trout and hazelnuts were on the diet. It also shows that one of the individuals had severe problems with her teeth.

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New PET/CT technique accurately diagnoses adrenal gland disorder, informs personalized treatment plans

SCIENMAG: Medicine & Health

Reston, VA—A novel imaging approach, 68Ga-pentixafor PET/CT, has been shown to accurately identify sub-types of primary aldosteronism (an adrenal gland disorder), outperforming traditional methods for diagnosis.

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DNA becomes our 'hands' to construct advanced nanoparticle materials

Science Daily: Pharmacology News

A new paper describes a significant leap forward in assembling polyhedral nanoparticles. The researchers introduce and demonstrate the power of a novel synthetic strategy that expands possibilities in metamaterial design. These are the unusual materials that underpin 'invisibility cloaks' and ultrahigh-speed optical computing systems.

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Knowing what dogs like to watch could help veterinarians assess their vision

SCIENMAG: Medicine & Health

Ever wonder what kind of TV shows your dog might choose if they could work the remote control? New research from the University of Wisconsin–Madison’s School of Veterinary Medicine provides some answers, but the study was more interested in solving a longstanding problem in veterinary medicine than turning canine companions into couch potatoes.

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Complement system causes cell damage in long Covid

Science Daily: Pharmacology News

Long Covid patients suffer from chronic symptoms such as fatigue or shortness of breath. As researchers have discovered, this is to some extent due to a part of our immune system called the complement system. The study identified a pattern in the blood proteins that will improve the diagnosis and perhaps also the targeted treatment of long Covid.

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6 in 10 sampled under-5s in India have micronutrient deficiencies, and 4 in 10 have anaemia, per survey of 17,230 children

SCIENMAG: Medicine & Health

6 in 10 sampled under-5s in India have micronutrient deficiencies, and 4 in 10 have anaemia, per survey of 17,230 children. Credit: Yadav et al., 2024, PLOS Global Public Health, CC-BY 4.0 ([link] 6 in 10 sampled under-5s in India have micronutrient deficiencies, and 4 in 10 have anaemia, per survey of 17,230 children.

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CRISPR 101 eBook.en español

addgene Blog

We have been gifted a Spanish translation of our CRISPR 101 eBook, 1st edition, that we are excited to make available as part of our eBook collection.

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RCSI research shows new benefits of weight loss for type 2 diabetes

SCIENMAG: Medicine & Health

18 January 2024: Researchers in the School of Population Health at RCSI University of Medicine and Health Sciences have provided new evidence of the health benefits of weight loss efforts that lead to diabetes remission for type 2 diabetes patients.

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Mouse Study Hints at New, Safe Way to Counter Allergies

Drugs.com

THURSDAY, Jan. 18, 2023 -- Allergic to peanuts? To cats? To pollen?A new targeted therapy may have the potential to help a person ward off an allergic reaction prompted by the specific source of their allergy, Northwestern University researchers.

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IIT: 5 new projects funded by the European Research Council to translate basic research results into real-world applications

SCIENMAG: Medicine & Health

Genoa (Italy), January 18th 2024 – Gianni Ciofani, Francesco Di Stasio, Giacomo Novembre, Velia Siciliano, and Agnieszka Wykowska are the researchers at the Istituto Italiano di Tecnologia (Italian Institute of Technology-IIT) who have been awarded Proof of Concept (PoC) grants by the European Research Council (ERC) today.

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Lightest black hole or heaviest neutron star? MeerKAT uncovers a mysterious object in Milky Way

Science Daily: Pharmacology News

An international team of astronomers have found a new and unknown object in the Milky Way that is heavier than the heaviest neutron stars known and yet simultaneously lighter than the lightest black holes known.

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BridgeBio strikes drug royalty deal for cash infusion

BioPharma Drive: Drug Pricing

The biotech will receive $500 million upon FDA approval of its rare disease drug acoramidis after selling 5% sales royalties to two investment firms.

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New patent for Springworks drug OGSIVEO

Drug Patent Watch

Annual Drug Patent Expirations for OGSIVEO Ogsiveo is a drug marketed by Springworks and is included in one NDA. It is available from one supplier. There are ten patents protecting… The post New patent for Springworks drug OGSIVEO appeared first on DrugPatentWatch - Make Better Decisions.

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