Mon.Jan 01, 2024

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Stachydrine represses the proliferation and enhances cell cycle arrest and apoptosis of breast cancer cells via PLA2G2A/DCN axis

Chemical Biology and Drug Design

Herbal medicine has become a safe, non-toxic and easily available source of cancer-treating compounds. Chinese motherwort (YiMuCao, Leonurus japonicus ) is a traditional Chinese herb showing beneficial effects for obstetrical and gynecological diseases. Among the active compounds, Stachydrine has been widely investigated, which makes us wonder whether Stachydrine can also exert its tumor-suppressive effects on BC.

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America's Doctors Offer 10 Health Resolutions as You Start a New Year

Drugs.com

MONDAY, Jan. 1, 2024 -- Still weighing whether to make a New Year’s resolution? Or perhaps regretting letting your healthy habits slide during the holidays?Either way, the American Medical Association (AMA) has ten recommendations to help.

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Which pharmaceutical companies have the most drug patents in Ireland?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Ireland. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is… The post Which pharmaceutical companies have the most drug patents in Ireland? appeared first on DrugPatentWatch - Make Better Decisions.

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FDA End-of-Year Release of Warning Letters Impresses (or Depresses)

FDA Law Blog: Biosimilars

By Douglas B. Farquhar & Aisha T. Evans* & Irene Namata* — Primacy and recency are recognized psychological phenomena: people tend to remember the first thing they hear, and the last. It’s why litigators concentrate on their opening statement to a jury, and their closing argument. Maybe that’s also why FDA last week publicized the highest number of important Warning Letters of the year (compared with prior releases in 2023).

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Determining Whether a Syringe Services Program Saves Money

Common Sense for Drug Policy Blog

Determining Whether a Syringe Services Program Saves Money "Methods "The research literature on the effectiveness of syringe services programs in controlling HIV transmission among persons who inject drugs and guidelines for syringe services program that are “functioning very well” were used to estimate the cost-saving threshold at which a syringe services program becomes cost-saving through preventing HIV infections versus lifetime treatment of HIV.

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Spending on Needle and Syringe Service Programs Globally

Common Sense for Drug Policy Blog

Spending on Needle and Syringe Service Programs Globally "Our systematic review identified 55 NSP unit cost estimates from 14 middle and high-income countries. Higher unit costs were associated with countries with higher HSRI and fewer syringes distributed, and with newer programs, which confirmed our hypothesis. The number of intervention components included was not seen to affect the unit cost, possibly because the majority of programs did not include any additional WHO-recommended interventio

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Cost-Effectiveness of Syringe Service Programs and Medications for Opioid Use Disorder

Common Sense for Drug Policy Blog

Cost-Effectiveness of Syringe Service Programs and Medications for Opioid Use Disorder "This study indicates that the SSP+MOUD [Syringe Service Program + Medications for Opioid Use Disorder] combination program is an effective harm-reduction strategy to prevent HCV cases among opioid IDUs and is cost-effective if payers are willing to pay $4,699 or more per avoided case of HCV.

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Cost Savings From Preventing HIV Infection

Common Sense for Drug Policy Blog

Cost Savings From Preventing HIV Infection "Effective treatment has increased life expectancy after HIV infection, and deaths from non-AIDS-related causes now exceed deaths from AIDS for those with HIV in the US [ 35 ]. Medical costs of treating HIV-infected individuals as they age now include costs of both HIV-related and HIV-unrelated medical care.

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Cost Savings From Syringe Service Programs in Baltimore, MD and Philadelphia, PA

Common Sense for Drug Policy Blog

Cost Savings From Syringe Service Programs in Baltimore, MD and Philadelphia, PA Editor's Note: This article has the following correction: "In the December 1, 2019 Supplement 2 of JAIDS Journal of Acquired Immune Deficiency Syndromes , in the article titled “Using Interrupted Time Series Analysis to Measure the Impact of Legalized Syringe Exchange on HIV Diagnoses in Baltimore and Philadelphia”, the authors mistakenly reported the estimated cost savings for Baltimore to be $62.4 million annually