BioPharma Drive: Drug Pricing
MARCH 14, 2025
The agency formulated its advice to manufacturers after coordinating with the CDC and Defense Department. An advisory meeting that's typically held was canceled last month.
Chemical Biology and Drug Design
MARCH 14, 2025
Fragment-based drug discovery (FBDD) was applied to cytochrome P450 3A4 reconstituted in Nanodiscs (NDs) with various lipid compositions. The choice of ND lipid influenced drug membrane interactions and fragment hit rates, demonstrating the critical role of the membrane environment in fragment screening for membrane proteins. ABSTRACT Membrane proteins (MPs) are important yet challenging targets for drug discovery.
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Drugs.com
MARCH 14, 2025
FRIDAY, March 14, 2025 -- Young kids can become seriously ill after drinking sugar-free slushies containing glycerol, a sugar alcohol used to help maintain the drinks icy texture, a new study warns.Children 7 and younger suffered a sudden sharp d.
Science Daily: Pharmacology News
MARCH 14, 2025
A study shows that electrical charges in sprays of water can cause chemical reactions that form organic molecules from inorganic materials. The findings provide evidence that microlightning may have helped create the building blocks necessary for early life on the planet.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
MARCH 14, 2025
FRIDAY, March 14, 2025 -- Only 43 percent of parents report they are able to find accurate and current information on avian influenza A(H5N1), commonly known as bird flu, according to the University of Michigan Health C.S. Mott Children's Hospital.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
MARCH 14, 2025
FRIDAY, March 14, 2025 -- Patients generally dont mind getting AI-written notes from their doctors office, unless they know the note came from a computer program, a new study says.Patients shown messages written by either AI, otherwise known as ar.
Sygnature Discovery
MARCH 14, 2025
Sygnature Discovery offers high throughput screening along with additional hit identification tools including virtual screening, knowledge-based design, and fragment screening. Employing a comprehensive strategy for hit identification, we use the most effective methods to accurately pinpoint hit series that have the highest potential for evolving into compounds with drug-like properties.
Drugs.com
MARCH 14, 2025
FRIDAY, March 14, 2025 -- A muscle-stimulating implant combined with a robotic exoskeleton can help restore movement in people paralyzed by a spinal cord injury, a new study says.The spinal cord implant delivers well-timed electrical pulses to.
Collaborative Drug
MARCH 14, 2025
The 2025 CDD Basel Science Community Meeting brought together researchers, industry experts, and thought leaders to discuss advancements in drug discovery, data management, FAIR data principles, and AI in research.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
MARCH 14, 2025
FRIDAY, March 14, 2025 -- Nostalgia might be met by eyerolls from some, as the emotion might inspire insipid images of rose-tinted glasses, gooey sentimentality and living in a time-lost past.But people prone to nostalgia have an edge when it comes.
Fierce BioTech
MARCH 14, 2025
Innovations in Analytical Testing, Biopharma, and Manufacturing Access our report today for a deep dive into the critical advancements shaping the future of pharmaceutical development. Discover how to ensure drugs meet the highest standards before they reach the market. smarcus Fri, 03/14/2025 - 09:39 Access our report today for a deep dive into the critical advancements shaping the future of pharmaceutical development.
Drugs.com
MARCH 14, 2025
FRIDAY, March 14, 2025 -- Playing with a dog for just 15 minutes can significantly reduce a persons stress, a new study reports.Stressed students who interacted with a friendly dog reported less stress, had a reduced heart rate and had lower l.
DS in Pharmatics
MARCH 14, 2025
Bringing a new drug to market requires more than just scientific innovation. It demands rigorous quality control, reliable manufacturing, and strict adherence to global regulatory standards.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
MARCH 14, 2025
FRIDAY, March 14, 2025 -- Most low-birth-weight toddlers are not on track to be ready to attend school, a new study says.Only one-third of babies born weighing less than 5.5 pounds are ready to attend school by ages 3 to 5, researchers reported in.
Covalent Modifiers
MARCH 14, 2025
ACS Chem. Biol. 2025 [link] Human Papillomavirus (HPV) is linked to multiple cancers, most significantly cervical cancer, for which HPV infection is associated with nearly all cases. Essential to the oncogenesis of HPV is the function of the viral protein E6 and its role in degrading the cell cycle regulator p53. Degradation of p53, and the resultant loss of cell cycle control, is mediated by E6 recruitment of the E3 ubiquitin ligase E6AP and subsequent ubiquitination of p53.
Drugs.com
MARCH 14, 2025
FRIDAY, March 14, 2025 -- Senate Democrats are raising concerns about Dr. Mehmet Ozs nomination to lead the Centers for Medicare and Medicaid Services (CMS), alleging he significantly underpaid Medicare and Social Security taxes in recent years.A m.
Chemical Biology and Drug Design
MARCH 14, 2025
ABSTRACT Twelve thiazole-pyrazole analogues 4 , 6 , and 8 were synthesized by introducing various pyrazole systems into the core, 2-((4-acetylphenyl)amino)-4-methylthiazole ( 2 ), through many synthetic approaches. The density functional theory (DFT) study of the synthesized analogues revealed coincided configurations of their highest occupied and lowest unoccupied molecular orbitals (HOMO and LUMO), except for the nitro derivatives, in which the intramolecular charge-transfer (CT) may be denote
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drug Target Review
MARCH 14, 2025
Sujeegar Jeevanandam, a veteran with 13 years of experience in life sciences R&D solutions, shares key insights into the evolving role of artificial intelligence in drug discovery. Drawing from his extensive work with pharmaceutical and biotechnology companies across North America, Sujeegar offers a unique perspective on how AI adoption might mirror previous technological shifts in the industry.
Drugs.com
MARCH 14, 2025
FRIDAY, March 14, 2025 -- Hours before his scheduled Senate confirmation, the White House has withdrawn the nomination of Dr. Dave Weldon to lead the U.S. Centers for Disease Control and Prevention (CDC).Weldon, a Republican and former congressman.
Perficient: Drug Development
MARCH 14, 2025
Quarkus has gained traction as a modern Java framework designed for cloud-native development. In my previous blog , I discussed why learning Quarkus is a great choice. Today, lets dive deeper into one of its standout features: Live Coding. What is Quarkus Live Coding? Live Coding in Quarkus provides an instant development experience where changes to your applications code, configuration, and even dependencies are reflected in real time without restarting the application.
Drug Channels
MARCH 14, 2025
Todays guest post comes from Jordan Armstrong, Vice President of Business Development at AssistRx. Jordan discusses the uptick in direct-to-consumer (DTC) models for life sciences organizations looking to navigate market challenges and improve patient access. He goes on to describe some potential risks and complexities associated with these models. To learn about AssistRxs technology solutions designed to simplify the patient experience and reduce channel costs, meet with AssistRx at the Drug Ch
Perficient: Drug Development
MARCH 14, 2025
Shoptalk Spring 2025 in Las Vegas is only a few weeks away, and our experts cannot wait to reconnect with brands and discuss where the industry is headed. They have been busy scheduling meetings , packing their mics, and making predictions about which technologies and strategies retailers and ecommerce brands will be placing their bets on this year.What do they believe is a safe bet?
BioPharma Drive: Drug Pricing
MARCH 14, 2025
President Trump’s nominee to run the FDA secured the Senate HELP Committee’s backing. Elsewhere, Sutro cut jobs and a cell and gene therapy pilot appeared to survive.
Drugs.com
MARCH 14, 2025
FRIDAY, March 14, 2025 -- Two Harvard medical school professors are suing the Trump administration, arguing that their research was unfairly removed from a government-run website.Their studies, focused on improving patient safety and reducing.
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