Broad Institute

JANUARY 9, 2025

Scientists engineer CRISPR enzymes that evade the immune system By Allessandra DiCorato January 9, 2025 Breadcrumb Home Scientists engineer CRISPR enzymes that evade the immune system The new genome-editing tools could lead to safer, more efficient gene therapies. By Allessandra DiCorato January 9, 2025 Credit: Natalie Velez, Broad Communications Related news Researchers uncover new CRISPR-like system in animals that can edit the human genome The core components of CRISPR-based genome-editing th

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Science Daily: Pharmacology News

JANUARY 9, 2025

A new study provides the first comprehensive global estimates of the amount of water stored in Earth's plants and the amount of time it takes for that water to flow through them. The information is a missing piece of the puzzle in understanding the global water cycle and how that cycle is being altered by changes in land use and climate.

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Drugs.com

JANUARY 9, 2025

THURSDAY, Jan. 9, 2025 -- Over-the-counter (OTC) drugs acetaminophen and ibuprofen are better at managing dental pain than opioids.People who had their wisdom teeth removed got better results from an acetaminophen/ibuprofen combo than with a.

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Drugs 111

Science Daily: Pharmacology News

JANUARY 9, 2025

A battery that needs feeding instead of charging? This is exactly what researchers have achieved with their 3D-printed, biodegradable fungal battery. The living battery could supply power to sensors for agriculture or research in remote regions. Once the work is done, it digests itself from the inside.

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Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

BioPharma Drive: Drug Pricing

JANUARY 9, 2025

The results suggest Bayer’s elinzanetant may help a broader group of women with vasomotor symptoms, which are associated with menopause as well as a common breast cancer therapy.

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Therapies Drugs 103

Science Daily: Pharmacology News

JANUARY 9, 2025

Hydroclimate whiplash -- rapid swings between intensely wet and dangerously dry weather -- has already increased globally due to climate change, with further large increases expected as warming continues, according to a team of researchers.

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Research 107

Science Daily: Pharmacology News

JANUARY 9, 2025

Sabre-toothed predators -- best know from the infamous Smilodon -- evolved multiple times across different mammal groups. A new study reveals why: these teeth were 'functionally optimal' and highly effective at puncturing prey.

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BioPharma Drive: Drug Pricing

JANUARY 9, 2025

Political and economic uncertainty hangs over the industry, while major bets on metabolic and immune disease drug research are set to play out.

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Drug Research Disease Research Drugs 67

Science Daily: Pharmacology News

JANUARY 9, 2025

Construction materials such as concrete and plastic have the potential to lock away billions of tons of carbon dioxide, according to a new study by civil engineers and earth systems scientists. The study shows that combined with steps to decarbonize the economy, storing CO2 in buildings could help the world achieve goals for reducing greenhouse gas emissions.

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Engineering 93

Drugs.com

JANUARY 9, 2025

THURSDAY, Jan. 9, 2024 -- Some of the most effective public policies for suicide prevention arent crafted with suicide or mental health in mind, a new study says.Efforts to increase the minimum wage, prohibit gender discrimination, or reduce a.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Science Daily: Pharmacology News

JANUARY 9, 2025

An international research team has discovered a new type of skeletal tissue that offers great potential for advancing regenerative medicine and tissue engineering.

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Engineering International Research 82

BioPharma Drive: Drug Pricing

JANUARY 9, 2025

The biotech will stop developing two drugs and lay off nearly three-quarters of its staff after its lead therapy wasn’t as potent in early testing as the company expected.

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Science Daily: Pharmacology News

JANUARY 9, 2025

Researchers have developed IRIS, a smart ring that allows users to point and click to control smart devices. The prototype Bluetooth ring contains a small camera which sends an image of the selected device to the user's phone. The user can control the device clicking a small button or -- for devices with gradient controls, such as a speaker's volume -- rotating the ring.

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Research 71

BioPharma Drive: Drug Pricing

JANUARY 9, 2025

The newly launched biotech is equipped with rights to a trio of weight loss medicines licensed from China-based Sciwind Biosciences, led by an oral therapy ready for Phase 2 testing.

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Licensing Licensing Therapies Drugs 62

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Science Daily: Pharmacology News

JANUARY 9, 2025

Chimpanzees bear genetic adaptations that help them thrive in their different forest and savannah habitats, some of which may protect against malaria, according to a study by an international team.

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Drugs.com

JANUARY 9, 2025

THURSDAY, Jan. 9, 2025 -- A pain-relieving medication might be safer for seniors than first thought.A new study published Jan. 7 in the Annals of Internal Medicine says Gabapentin is widely used to help treat chronic pain and nerve pain.

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International 59

Covalent Modifiers

JANUARY 9, 2025

Matthew Bogyo, Tulsi Upadhyay, Emily Woods, Stephen Ahator. Kjersti Julin, Franco Faucher, Marijn Hollander, Nichole Pedowitz, Daniel Abegg, Isabella Hammond, Ifeanyichukwu Eke, Sijie Wang, Shiyu Chen, John Bennett, Jeyun Jo, Christian Lentz, Alex Adibekian, Matthias Fellner Research Square Preprint 2025 [link] 10.21203/rs.3.rs-5494070/v1 Staphylococcus aureus is a leading cause of bacteria-associated mortality worldwide.

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Fragment Screening Regulations Research 59

Drugs.com

JANUARY 9, 2025

THURSDAY, Jan. 9, 2025 -- AI might be able to boost the success rates of in vitro fertilization among hopeful families.An AI program can help doctors analyze ultrasound scans to determine the best timing for a hormone injection associated with egg.

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Doctors 59

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Covalent Modifiers

JANUARY 9, 2025

Tomonori Tamura, Masaharu Kawano, and Itaru Hamachi Chemical Reviews 2024 DOI: 10.1021/acs.chemrev.4c00745 The term undruggable refers to proteins or other biological targets that have been historically challenging to target with conventional drugs or therapeutic strategies because of their structural, functional, or dynamic properties. Drugging such undruggable targets is essential to develop new therapies for diseases where current treatment options are limited or nonexistent.

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Drugs Therapies Treatment Disease 59

Drugs.com

JANUARY 9, 2025

THURSDAY, Jan. 9, 2025 -- Basking in a sauna can be a nice way to relieve stress or relax muscles following a workout.But soaking too long can increase a persons risk of heat stroke, particularly if they arent well-hydrated, doctors warn.Most cas.

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Doctors 59

Collaborative Drug

JANUARY 9, 2025

Drug Discovery Industry Roundup with Barry Bunin January 9th, 2025

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Drugs 52

Drugs.com

JANUARY 9, 2025

THURSDAY, JAN. 8, 2025 -- Got brain fog? Can't concentrate because you didn't sleep well -- or sleep much at all -- last night? Tiredness and fatigue from sleep deprivation are common problems, says the National Sleep Foundation (NSF). Inadequate.

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Production 52

BioPharma Drive: Drug Pricing

JANUARY 9, 2025

Nearly 30% of the funding poured into healthcare startups last year, including for biotechs, went to companies leveraging artificial intelligence, according to Silicon Valley Bank.

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Drugs.com

JANUARY 9, 2025

THURSDAY, Jan. 9, 2025 -- Exercising now can increase your chances of successfully fighting cancer in the future.Even low levels of exercise provided protection against cancer, a new study published Jan. 7 in the British Journal of Sports Medicine.

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Disease 52

Drug Patent Watch

JANUARY 9, 2025

Navigating the complex landscape of drug development and manufacturing can be a daunting task. Enter the Contract Development and Manufacturing Organization (CDMO) a lifeline for many startups looking to bring their innovative therapies to market. But how do you, as a startup, ensure you’re making the most of this crucial partnership? Let’s dive into the best CDMO practices that can set your startup on the path to success.

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Compliance Drug Development Therapies Pharma Companies 52

Drugs.com

JANUARY 9, 2025

THURSDAY, Jan. 9, 2025 -- Movement is medicine, or so they tell people with knee osteoarthritis -- but are they right?A recent evidence review calls into question just how helpful exercise can be for easing the pain of knee arthritis.Exercise p.

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Research 52

Perficient: Drug Development

JANUARY 9, 2025

Objective Automate the deployment of Azure Kubernetes Service (AKS) using Terraform Cloud Workspaces. This ensures Infrastructure as Code (IaC) is centrally managed, and all changes are traceable. 1. Set Up a Terraform Cloud Workspace Free Account Step 1: Create a Terraform Cloud Account Navigate to [link] Sign up or log in with a valid email ID. Step 2: Create an Organization After logging in, create an organization (if one doesnt already exist): a.

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FDA Law Blog: Biosimilars

JANUARY 9, 2025

By Anne K. Walsh & Hyman, Phelps & McNamara, P.C. & Douglas B. Farquhar This is the first in a series of blog posts on tips for successfully handling an FDA inspection. Using publicly available examples, these lessons will illustrate potential pitfalls and strategies for interacting with FDA during and after an inspection. Although FDA has long taken the position that it has broad authority in how it conducts its inspections, it was not until 2012 that Congress put some teeth behind

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FDA Regulations International Drugs 59

Perficient: Drug Development

JANUARY 9, 2025

MuleSoft and Boomi are two popular businesses that provide reliable solutions for integrating devices, data, and apps in the constantly changing field of enterprise integration. Every platform has distinct characteristics and advantages that make it appropriate for various company requirements. To help you make a wise choice, we will examine the key features and elements of Boomi and MuleSoft in this blog.

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Science Daily: Pharmacology News

JANUARY 9, 2025

A recent study has uncovered the surprising evolutionary origin of the mammalian outer ear, linking it to the gills of ancient fish and marine invertebrates. The research reveals that both structures are composed of elastic cartilage and shares gene control elements that hint at their connection. This finding sheds new light on the evolution of the mammalian ear, highlighting how structures can transform over time to serve new functions.

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Research 92

Perficient: Drug Development

JANUARY 9, 2025

The Evolution of Java and Its Significance in Enterprise Applications Java has been the go-to language for enterprise software development for decades, offering a solid and reliable platform for building scalable applications. Over the years, it has evolved with each new version. Security Enhancements of Java 17 Long-Term Support Java 17, being a Long-Term Support (LTS) release, is a strategic choice for enterprises using MuleSoft.

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Compliance 52

Science Daily: Pharmacology News

JANUARY 9, 2025

Antibiotic-resistant Salmonella is a serious public health concern that has increased in recent years as the bacteria have developed ways to survive drugs. According to the U.S. Centers for Disease Control and Prevention, people can get Salmonella from eating contaminated food products or from infected people or animals -- typically via unintentional contact with feces via touching hands or stroking a pet.

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Perficient: Drug Development

JANUARY 9, 2025

The Agentforce World Tour has been a groundbreaking series of events, showcasing how Salesforce is revolutionizing work and customer service with AI-driven solutions. Here are some key takeaways from the recent sessions in New York , Atlanta , Dallas , and Chicago. New York – November 20 Harry Wilson, Senior Solutions Architect, highlighted how Salesforce is transforming internal business processes with Slack.

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