Science Daily: Pharmacology News
MAY 6, 2024
About 79% of clinical trial participants experienced measurable improvement after receiving experimental, CRISPR-based gene editing that is designed to fix a rare form of blindness, according to a new article.
ASPET
MAY 6, 2024
Substantial clinical and preclinical evidence indicates that transient receptor potential vanilloid 1 (TRPV1) receptors are expressed on terminals of colorectal chemoreceptors and mechanoreceptors and are involved in various rectal hypersensitivity disorders with common features of colorectal overactivity. These stimulatory properties of TRPV1 receptors on colorectal function suggested that brief stimulation of TRPV1 might provide a means of pharmacologically activating the colorectum to induce
Drugs.com
MAY 6, 2024
MONDAY, May 6, 2024 -- Scientists are busy working on a vaccine that might fight strains of the COVID virus SARS-CoV-2 that haven't even emerged yet.The effort from a British team at the University of Cambridge is already showing promise in mouse.
ASPET
MAY 6, 2024
Constitutive androstane receptor (CAR) and peroxisome proliferator-activated receptor α (PPARα) are members of the nuclear receptor superfamily, which regulates various physiological and pathological processes. Phase separation is a dynamic biophysical process that biomacromolecules form liquid-like condensates, which have been identified as a contributor to many cellular functions, such as signal transduction and transcription regulation.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
MAY 6, 2024
MONDAY, May 6, 2024 -- An injectable gene therapy caused measurable improvements in vision among a small group of people with inherited blindness, an early-stage clinical trial says.Researchers recruited 14 people with Leber Congenital Amaurosis.
ASPET
MAY 6, 2024
Cancers affecting women, such as breast, uterine, ovarian, endometrial and cervical cancers, have become increasingly prevalent. The growing incidence and death rates associated with these cancers warrant the development of innovative and alternative approaches to current treatments. This article investigates the association of women's cancers with a molecular target known as protease-activated receptor 2 (PAR2), a G-protein coupled receptor that is expressed on the surface of cancer cells.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
MAY 6, 2024
MONDAY, May 6, 2024 -- Worries over health-related costs are plaguing the minds of older Americans of all backgrounds, a new poll suggests.Five of the six health-related issues that most people found very concerning had to do with health care.
BioPharma Drive: Drug Pricing
MAY 6, 2024
A 12-year-old boy in the Washington, D.C., area is set become the first patient treated with Lyfgenia since its U.S. approval last December.
Drug Target Review
MAY 6, 2024
Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? My journey in STEM has been both challenging and immensely fulfilling. Early in my career, I had a bad experience in one of my first jobs, helping in the lab as a young student. My professor’s seeming support of my work quickly shifted into a more personal interest in me.
Drugs.com
MAY 6, 2024
MONDAY, May 6, 2024 -- A new combination therapy appears to boost the response rate for liver cancer patients receiving immunotherapy, according to results from a phase 2 clinical trial.The combo therapy involves bavituximab, a drug that.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
FDA Law Blog: Biosimilars
MAY 6, 2024
By Lisa M. Baumhardt, Senior Medical Device Regulation Expert & Adrienne R. Lenz, Principal Medical Device Regulation Expert — FDA recently issued a draft guidance which would update the agency’s Cybersecurity in Medical Devices: Quality System Considerations and Content of Premarket Submissions guidance. The draft guidance provides recommendations on what is required to meet cybersecurity obligations under section 524B of the Food, Drug and Cosmetic Act (FD&C).
Science Daily: Pharmacology News
MAY 6, 2024
Billions of years ago, Venus may have harbored as much water as Earth. Today, almost all of it has disappeared. A new study may help to explain why.
Drugs.com
MAY 6, 2024
MONDAY, May 6, 2024 -- A potentially dangerous spike in blood pressure known as preeclampsia can occur in 1 in every 25 pregnancies, but an accurate test to spot those women at highest risk has remained elusive.Now, Canadian researchers at.
Science Daily: Pharmacology News
MAY 6, 2024
Astronomers observed the elusive starlight surrounding some of the earliest quasars in the universe. The findings may shed light on how the earliest supermassive black holes became so massive despite having a relatively short amount of cosmic time in which to grow.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
MAY 6, 2024
MONDAY, May 6, 2024 -- Pets and pet owners who come into contact with Bausch & Lomb's "Project Watson" dog eye wipes could be at risk for infection if the products come from certain lots.The wipes are used to clean a dog's eyelids, but two.
Science Daily: Pharmacology News
MAY 6, 2024
New discoveries about Jupiter could lead to a better understanding of Earth's own space environment and influence a long-running scientific debate about the solar system's largest planet.
Drugs.com
MAY 6, 2024
MONDAY, May 6, 2024 -- Everyone knows that specific type of sports parent – the over-the-top dad or mom who curses, shouts and even becomes physically aggressive during their kid’s match.While they might think they’re cheering their kid to.
BioPharma Drive: Drug Pricing
MAY 6, 2024
With many chemotherapy and ADHD drugs stuck in stubbornly short supply, several agencies are looking for new solutions.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
MAY 6, 2024
MONDAY, May 6, 2024 — Two-thirds of kids who suffer a subtle type of epileptic seizure go undiagnosed when they seek emergency room treatment, new research shows.“We do not know how many people are walking around with seizures that they are.
DrugBank
MAY 6, 2024
Biologics are revolutionizing modern healthcare. Unlike conventional chemical-based medicines, biologics offer targeted therapies derived from living cells, which can result in more effective and personalized treatments. This category encompasses a broad spectrum of treatments including vaccines, blood components, gene therapies, and more, each tailored to combat diseases in highly specific ways.
Drugs.com
MAY 6, 2024
MONDAY, May 6, 2024 -- Nearly 100,000 U.S. children lost a parent in 2020 to gun violence or drug overdose, a three-fold rise since 1999, according to a new study.
BioPharma Drive: Drug Pricing
MAY 6, 2024
One analyst thinks the collaboration “bodes well” for Gossamer, which has had trouble convincing investors its drug seralutinib can compete on the market.
Drug Patent Watch
MAY 6, 2024
Annual Drug Patent Expirations for SYMDEKO+%28COPACKAGED%29 Symdeko (copackaged) is a drug marketed by Vertex Pharms Inc and is included in one NDA. It is available from one supplier.
BioPharma Drive: Drug Pricing
MAY 6, 2024
The British drugmaker, which has made genetic medicine a larger priority of late, added $140 million to a deal to develop up to 10 gene and cell therapies.
Perficient: Drug Development
MAY 6, 2024
Part 3 in our “ unpack the stack ” series on composable martech is all about the data – specifically, access to the data – the middle layer of the stack. The next set of capabilities we’re exploring is Orchestration and Federation. These two capabilities go well together because they are very similar and have some overlap, so let’s unpack ’em.
Drug Patent Watch
MAY 6, 2024
Annual Drug Patent Expirations for IMBRUVICA Imbruvica is a drug marketed by Pharmacyclics Llc and is included in three NDAs. It is available from one supplier.
BioPharma Drive: Drug Pricing
MAY 6, 2024
The ability to modify drug formulations in real time and dosage strengths is crucial, while adhering to all regulatory standards and maintaining cGMP standards.
Perficient: Drug Development
MAY 6, 2024
Over the last year, I’ve witnessed significant changes transforming the manufacturing industry. One driver of this change – which won’t surprise you – is artificial intelligence (AI) , and it is the most influential force shaping both professional and personal lives. However, AI isn’t the only noteworthy trend manufacturers need to focus on.
Olympian Clinical Research
MAY 6, 2024
Plaque psoriasis, a persistent autoimmune condition characterized by red, scaly patches on the skin, has affected millions worldwide, influencing both physical health and emotional well-being. The journey toward effective treatments has been long and evolving, with recent breakthroughs offering new hope to those living with this challenging condition.
Perficient: Drug Development
MAY 6, 2024
Where’s my order? What’s my tracking number? How do I order spare parts? When will the service technician arrive? These are all common questions lobbed into customer service centers. Your contact center is a living knowledge base where your agents not only cover common questions, but also provide expert-level answers to the complex questions your customers ask.
Fierce BioTech
MAY 6, 2024
Recombinant Antibody Engineering Techniques and Strategies Dive into the cutting-edge world of recombinant antibody engineering, from optimizing your antibody plasmid, to antibody maturation and humanization. Explore innovative techniques and strategies that enhance antibody efficacy, paving the way for breakthroughs in therapeutic development. jkarimi Mon, 05/06/2024 - 10:50 Dive into the cutting-edge world of recombinant antibody engineering, from optimizing your antibody plasmid, to antibody
Drugs.com
MAY 6, 2024
MONDAY, May 6, 2024 -- Parents of newborns diagnosed with cystic fibrosis often are confused about both the disease and their next steps, a new national survey has found.In fact, about half of new parents don’t even know that newborns are.
Drug Patent Watch
MAY 6, 2024
This chart shows the pharmaceutical companies with the most supplementary protection certificates (SPCs) in France.
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