Wed.Dec 04, 2024

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How did humans and dogs become friends? Connections in the Americas began 12,000 years ago

Science Daily: Pharmacology News

A new study sheds light on how long humans in the Americas have had relationships with the ancestors of today's dogs -- and asks an 'existential question': What is a dog?

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Lilly’s Zepbound beats Novo’s Wegovy in high-stakes obesity drug trial

BioPharma Drive: Drug Pricing

Results from the head-to-head study showed treatment with Zepbound resulted in 47% greater relative weight loss than Wegovy, a finding that could advantage Lilly in the companies’ market competition.

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20th century lead exposure damaged American mental health

Science Daily: Pharmacology News

Exposure to car exhaust from leaded gas during childhood altered the balance of mental health in the U.S. population, making generations of Americans more depressed, anxious and inattentive or hyperactive, according to researchers. They estimate that 151 million cases of psychiatric disorder over the past 75 years have resulted from American children's exposure to lead.

Research 328
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Zepbound Bests Wegovy for Weight Loss in New Trial

Drugs.com

WEDNESDAY, Dec. 4, 2024 -- Zepbound, the new GLP-1 weight-loss drug from Eli Lilly & Co., has outperformed its main competitor, Wegovy, in a clinical trial funded by Lilly."Given the increased interest around obesity medications, we conducted.

Trials 279
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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The surprising effect of stress on your brain’s reward system

Science Daily: Pharmacology News

Some people bounce back from trauma, but others get caught in depressive loops that sap the joy from their lives.

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Largest study of CTE in male ice hockey players finds odds increased 34% with each year played

Science Daily: Pharmacology News

A large study, of 77 deceased male ice hockey players, has found that the odds of having chronic traumatic encephalopathy (CTE) increased by 34% each year played, and 18 of 19 National Hockey League players had CTE. CTE is a neurodegenerative disease caused by repeated traumatic brain injuries and most frequently found in former contact sport athletes exposed to repetitive head impacts (RHI).

Disease 302
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Could High-Fructose Corn Syrup in Foods Help Speed Cancer?

Drugs.com

WEDNESDAY, Dec. 4, 2024 -- The sugar known as fructose could be a kind of rocket fuel for cancer cells, and lowering fructose intake could be one way to fight the disease, new research suggests.Fructose is already ubiquitous in American diets, due.

Disease 264
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We might feel love in our fingertips - but did the Ancient Mesopotamians?

Science Daily: Pharmacology News

A multidisciplinary team of researchers studied a large body of texts to find out how people in the ancient Mesopotamian region (within modern day Iraq) experienced emotions in their bodies thousands of years ago.

Research 296
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American Seniors Struggle to Pay Medical Bills More Than Peers in Other Wealthy Countries

Drugs.com

WEDNESDAY, Dec. 4, 2024 -- American seniors still pay more for health care than their counterparts in most other wealthy countries do, despite coverage by Medicare, a new study finds.They are also more likely to postpone or skip needed care because.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Owning a home in the US linked to longer life

Science Daily: Pharmacology News

A new study finds that owning a home in early adult life adds approximately four months to the lives of male Americans born in the early twentieth century.

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Even Minutes-Long Exercise 'Bursts' Can Help Women's Hearts

Drugs.com

WEDNESDAY, Dec. 4, 2024 -- Take the stairs. Tote heavy shopping bags. Walk up that hill. Play tag with a kid or a pet.Weaving these tiny bursts of vigorous physical activity into everyday life can halve a woman’s risk of a heart attack, a new study.

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The heart has its own 'brain'

Science Daily: Pharmacology News

New research shows that the heart has a mini-brain -- its own nervous system that controls the heartbeat. A better understanding of this system, which is much more diverse and complex than previously thought, could lead to new treatments for heart diseases.

Treatment 285
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Dec 2024 - Q4 Product Update Webinar: Curves and AI

Collaborative Drug

We recently hosted our December 2024 Q4 Product Update Webinar, showcasing significant enhancements to the CDD Vault platform. The webinar covered four key modules: Curves and AI. Let's dive into the exciting updates for each module.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Massive asteroid impacts did not change Earth's climate in the long term

Science Daily: Pharmacology News

Two massive asteroids hit Earth around 35.65 million years ago, but did not lead to any lasting changes in the Earth's climate, according to a new study.

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Atea plans Phase 3 study for hepatitis C drug after mid-stage results

BioPharma Drive: Drug Pricing

The struggling biotech company is looking to break into the lucrative hepatitis C market with the promise of an easier treatment regimen.

Treatment 252
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Astronomers close to solving mystery of how universe's giant galaxies formed

Science Daily: Pharmacology News

Astrophysicists find the birth sites of gigantic elliptical galaxies which they say gives new clues about how they were formed. The galaxies look like bulging footballs and how they were created remains a mystery to scientists -- until now.

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20th Century Lead Exposures Took Grim Toll on Americans' Health

Drugs.com

WEDNESDAY, Dec. 4, 2024 -- Decades of lead exposure from car exhaust altered the mental health of millions of Americans, making them more prone to depression, anxiety and ADHD, a new study claims.Lead was first added to gasoline in 1923 to help.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Mammoth as key food source for ancient Americans

Science Daily: Pharmacology News

Scientists have uncovered the first direct evidence that ancient Americans relied primarily on mammoth and other large animals for food. Their research sheds new light on both the rapid expansion of humans throughout the Americas and the extinction of large ice age mammals.

Research 282
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E. Coli Outbreak Linked to McDonald's Quarter Pounders Declared Over

Drugs.com

WEDNESDAY, Dec. 4, 2024 (Healtday News) -- An investigation into an E. coli outbreak linked to McDonald's Quarter Pounders has officially been closed, the U.S. Food and Drug Administration announced Tuesday.In total, 104 people from 14 states were.

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Manta rays inspire fast swimming soft robot yet

Science Daily: Pharmacology News

A team of researchers has beaten its own record for the fastest swimming soft robot, drawing inspiration from manta rays to improve their ability to control the robot's movement in the water.

Research 274
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Almost a Third of U.S. Retail Pharmacies Have Closed Since 2010

Drugs.com

WEDNESDAY, Dec. 4, 2024 -- About a third of America’s pharmacies have closed since 2010, amounting to an “unprecedented decline” in neighborhood drug stores, a new study finds.The drop began in 2018, primarily driven by store closures among chain ph.

Pharmacy 246
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Optimizing Generic Drug Development with Machine Learning

Drug Patent Watch

The pharmaceutical industry is undergoing a significant transformation with the advent of machine learning methods. These methods have the potential to revolutionize the drug discovery process by enhancing the efficiency and accuracy of identifying and developing new drug candidates.

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Smoking/Vaping Combo Lowers Odds for Quitting Nicotine

Drugs.com

WEDNESDAY, Dec. 4, 2024 -- People who smoke and vape are less able to break free of their nicotine addiction than folks who only have one of those habits, a new review concludes.Instead, these “dual users” are more likely to eventually drop vaping a.

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Dewpoint, Mitsubishi partner on ALS drug in deal worth up to $480M

BioPharma Drive: Drug Pricing

The collaboration is another vote of confidence in Dewpoint’s biomolecular condensates research, which had already attracted interest from the likes of Bayer and Novo Nordisk.

Drugs 156
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Genes Highlight Who'll Benefit From Multiple Myeloma Treatment With Venclexta

Drugs.com

WEDNESDAY, Dec. 4, 2024 -- Genetic tests can show which patients with the blood cancer multiple myeloma should respond to targeted therapy, a new study finds. A special six-gene pattern can help predict who are more likely to respond well to.

Treatment 162
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UnitedHealthcare CEO Brian Thompson fatally shot in NYC

BioPharma Drive: Drug Pricing

The NYPD confirmed the shooting, which caused UnitedHealth to end an investor conference early on Wednesday. Thompson, 50, had been with UnitedHealth since 2004.

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