Mon.Dec 18, 2023

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AI's memory-forming mechanism found to be strikingly similar to that of the brain

Science Daily: Pharmacology News

An interdisciplinary team consisting of researchers has revealed a striking similarity between the memory processing of artificial intelligence (AI) models and the hippocampus of the human brain. This new finding provides a novel perspective on memory consolidation, which is a process that transforms short-term memories into long-term ones, in AI systems.

Research 139
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Q&A: How to jump-start new psychiatric and neurological drug development

Broad Institute

Q&A: How to jump-start new psychiatric and neurological drug development By Tom Ulrich December 18, 2023 Breadcrumb Home Q&A: How to jump-start new psychiatric and neurological drug development Stanley Center director Steve Hyman talks about a new report he co-authored that explores the obstacles in developing new treatments and how to overcome them By Tom Ulrich December 18, 2023 Steven Hyman Related people Steven Hyman Related programs Stanley Center for Psychiatric Research Related News Scien

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Integrating network pharmacology and experimental verification to investigate the pharmacological mechanisms of Buzhong Yiqi decoction in the treatment of non?small cell lung cancer

Chemical Biology and Drug Design

The Buzhong Yiqi decoction can suppress the development and progression of non-small cell lung cancer in vitro. The Buzhong Yiqi decoction could inhibit cell viability and proliferation and induce cell apoptosis of non-small cell lung cancer A549 and H1299 cells. The Buzhong Yiqi decoction regulated the PI3K-AKT signaling pathway in non-small cell lung cancer A549 cells.

Treatment 100
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Exoplanets'climate -- it takes nothing to switch from habitable to hell

Science Daily: Pharmacology News

The Earth is a wonderful blue and green dot covered with oceans and life, while Venus is a yellowish sterile sphere that is not only inhospitable but also sterile. However, the difference between the two bears to only a few degrees in temperature. A team of astronomers has achieved a world's first by managing to simulate the entirety of the runaway greenhouse process which can transform the climate of a planet from idyllic and perfect for life, to a place more than harsh and hostile.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Synthetic derivatives of natural cinnamic acids as potential anti?colorectal cancer agents

Chemical Biology and Drug Design

Twenty-four new derivatives of natural cinnamic acids were designed and synthesized as promising anti-colorectal cancer agents. Their activity was evaluated against HCT116, SW480, HT29, LoVo, and DLD1 cells, in which they induce apoptosis. Abstract Cinnamic acid and its derivatives represent attractive building blocks for the development of pharmacological tools.

Research 100
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COVID Can Raise Long-Term Odds for Irregular Heartbeat

Drugs.com

MONDAY, Dec. 18, 2023 -- Add another post-COVID hazard to the list: Research suggests having the illness could raise risks for dangerous irregular heart beats.According to Swedish researchers, the odds a person might develop atrial fibrillation --.

Research 111

More Trending

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Cinnamon in Applesauce That Sickened Kids May Have Been Deliberately Tainted With Lead

Drugs.com

MONDAY, Dec. 18, 2023 -- Cinnamon used in applesauce pouches that have been tied to high lead levels in kids may have been deliberately tainted with the toxic element, a source at the U.S. Food and Drug Administration says."We’re still in the.

Drugs 111
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Artificial intelligence can predict events in people's lives

Science Daily: Pharmacology News

Artificial intelligence can analyze registry data on people's residence, education, income, health and working conditions and, with high accuracy, predict life events.

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Men Who Want to Be Dads Should Take a Break From Alcohol

Drugs.com

MONDAY, Dec. 18, 2023 -- Much has been made of the effects a pregnant woman's drinking could have on the health of her unborn child.But alcohol consumption by men also increases the risk of birth defects in newborns – and a new study shows that.

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New patent expiration for Glaxosmithkline drug VENTOLIN HFA

Drug Patent Watch

Annual Drug Patent Expirations for VENTOLIN+HFA Ventolin Hfa is a drug marketed by Glaxosmithkline and is included in one NDA. It is available from nine suppliers. There are two patents… The post New patent expiration for Glaxosmithkline drug VENTOLIN HFA appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 96
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Drug Discovery Industry Roundup with Barry Bunin — December 18, 2023

Collaborative Drug

Discover the impact of 'junk DNA' on cancer, teen obesity treatments, Neanderthal genes on sleep patterns, and Nobel discoveries shaping medicine

DNA 102
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Team led by UMASS Amherst discovers how to sabotage antibiotic-resistant ‘superbugs’

SCIENMAG: Medicine & Health

Antibiotic-resistant “superbugs” that can defeat efforts to kill them are an urgent public health crisis, and according to the Centers for Disease Control, more than 2.8 million antibiotic-resistant infections occur each year. Researchers across the world are scrambling to meet the challenge.

Disease 91
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Rate of Severe Obesity in Kids Is Rising Again

Drugs.com

MONDAY, Dec. 18, 2023 -- Severe obesity appears to be on the rise among young U.S. children, based on data from a federal supplemental nutrition program.About 2% of children between 2 and 4 years of age in the Women, Infants and Children (WIC).

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Toronto study identifies new concepts for GLP-1 action in the brain, the 2023 Science magazine breakthrough of the year

SCIENMAG: Medicine & Health

Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine. Credit: please credit Colin Dewar Research pioneer Dr.

Science 90
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Pivotal Life Sciences reloads with $389M, hunting for deals in a downturn

BioPharma Drive: Drug Pricing

The firm is tracking startups that launched during the biotechnology sector’s peak a few years ago but now need fresh funds to move their programs forward, one of its investors said.

Science 75
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Melatonin and carcinogenesis in mice: The 50th anniversary of relationships

SCIENMAG: Medicine & Health

“[…] murine models proved to be valuable and, in some cases, indispensable for advancing melatonin applications in oncology […].” Credit: 2023 Anisimov and Golubev “[…] murine models proved to be valuable and, in some cases, indispensable for advancing melatonin applications in oncology […].

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Apes remember friends they haven't seen for decades

Science Daily: Pharmacology News

Apes recognize photos of groupmates they haven't seen for more than 25 years and respond even more enthusiastically to pictures of their friends, a new study finds. The work, which demonstrates the longest-lasting social memory ever documented outside of humans, and underscores how human culture evolved from the common ancestors we share with apes, our closest relatives.

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Early-life diseases linked to lifelong childlessness

SCIENMAG: Medicine & Health

Led by Aoxing Liu and senior authors Melinda Mills, Andrea Ganna and an international team, the study examined the link between 414 early-life diseases and lifetime childlessness in over 2.5 million individuals born in Finland and Sweden.

Disease 85
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Resolve to Keep Your Allergies, Asthma in Check in 2024

Drugs.com

MONDAY, Dec. 18, 2023 -- If you're one of the 50 million Americans with asthma or allergies, 2024 is another year to redouble efforts to manage them.But how?“It’s not always easy to get allergies and asthma under control,” allergist Dr.

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Thalassemia screening in Thailand: Medical Sciences Dean advocates for elevated trust

SCIENMAG: Medicine & Health

– Insights from Professor Sakorn Pornprasert, Dean, Faculty of Associated Medical Sciences at Chiang Mai University, on raising thalassemia awareness in Thailand. Credit: BGI Genomics – Insights from Professor Sakorn Pornprasert, Dean, Faculty of Associated Medical Sciences at Chiang Mai University, on raising thalassemia awareness in Thailand.

Science 83
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Most U.S. Parents Plan to Vaccinate Kids Against Flu, RSV: Survey

Drugs.com

MONDAY, Dec. 18, 2023 -- Most parents plan to have their kids vaccinated against influenza and respiratory syncytial virus (RSV), even as COVID-19 vaccine acceptance flags, a new poll finds.Seven in 10 parents (71%) plan to have their children get.

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New patent expiration for Glaxo Grp drug ADVAIR HFA

Drug Patent Watch

Annual Drug Patent Expirations for ADVAIR+HFA Advair Hfa is a drug marketed by Glaxo Grp Ltd and is included in one NDA. It is available from three suppliers. There are… The post New patent expiration for Glaxo Grp drug ADVAIR HFA appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 77
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Point radiopharma drug results disappoint in prostate cancer study

BioPharma Drive: Drug Pricing

While the study met its goal, the drug’s benefit was less than analysts had predicted, an outcome that could hasten a planned takeover by Eli Lilly.

Drugs 70
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New patent for Astellas drug XTANDI

Drug Patent Watch

Annual Drug Patent Expirations for XTANDI Xtandi is a drug marketed by Astellas and is included in two NDAs. It is available from one supplier. There are three patents protecting… The post New patent for Astellas drug XTANDI appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 64
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Neighborhoods Influence Whether or Not Folks Take Their Heart Failure Meds

Drugs.com

MONDAY, Dec. 15, 2023 -- Heart failure is a major killer. However, a new study finds that heart failure patients living in poorer neighborhoods are much less likely to pick up lifesaving meds from local pharmacies, compared to patients living in.

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Trials, Data, Diversity – H1’s Top 5 Diagnoses (Predictions) for Biotech and Pharma in 2024

H1 Blog

How will AI impact clinical trials? Will FDA legislation improve diversity? What platforms will key opinion leaders adopt? Every year, we take a look at annual predictions to help life sciences, pharmaceutical, and healthcare companies understand larger industry trends and dynamics to prepare for the new year. These forecasts, curated by our own experts and thought leaders, shed light on the changes set to reshape the healthcare and pharmaceutical sectors.

Trials 64
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What Is Dandruff & How Is It Treated?

Drugs.com

MONDAY, Dec. 18, 2023 -- Dandruff becomes more common in the cold winter months, when the chilly air and dry heat causes a person’s scalp to flake and itch.But while it might be an annoying and unattractive condition, dandruff doesn’t mean you.

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Global inventory of sound production brings us one step closer to understanding aquatic ecosystems

Science Daily: Pharmacology News

Our understanding of which aquatic species produce sounds just took a big step forward. Scientists have created an inventory of species confirmed or expected to produce sound underwater.

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Foundation behind Novo Nordisk to invest $260M in vaccine R&D

BioPharma Drive: Drug Pricing

The newly established initiative, which consists of a research center and an accelerator, will focus on developing vaccines for tuberculosis, influenza and group A streptococcus.

Vaccine 60
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Fatigued 'Frenchies': Flat-Faced Dogs Get Worse Sleep

Drugs.com

MONDAY, Dec. 18, 2023 -- French Bulldogs might be the most widespread breed in the world, but the fancy, flat-faced pooches pay a high price for their popularity, a new study warns.The shortened skulls and large, round heads that make Frenchies so.

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Structure shares sink as obesity pill misses expectations in small study

BioPharma Drive: Drug Pricing

Results from a Phase 2 trial fell short of what’s been seen with a similar Eli Lilly medicine, causing the closely watched biotech’s shares to plummet.

Trials 64
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LWC – Validating Email Already exists in Database using Apex

Perficient: Drug Development

Hello Trailblazers, In this blog post, we are going to learn how we can apply custom validation in LWC to the Email field to make it unique. We’ll validate whether the Email is already exist in database or not. Acceptance Criteria : In an account creation form, create a custom validation on the Email field so that the user should not enter a duplicate email value.

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New tentative approval for Ascent Pharms drug icosapent ethyl

Drug Patent Watch

Icosapent ethyl is the generic ingredient in two branded drugs marketed by Apotex, Dr Reddys, Hikma, Strides Pharma, Teva Pharms Usa, Zydus, and Amarin Pharms and, and is included in… The post New tentative approval for Ascent Pharms drug icosapent ethyl appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 59