Sun.Jan 14, 2024

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Study reveals function of little-understood synapse in the brain

Science Daily: Pharmacology News

New research for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer's disease, to a type of brain cancer known as glioma. Neuroscientists focused on the synapse connecting neurons to a non-neuronal cell, known as oligodendrocyte precursor cells.

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Design, Synthesis, X-ray Crystallography, and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease

Covalent Modifiers

Md Ashraf-Uz-Zaman, Teck Khiang Chua, Xin Li, Yuan Yao, Bala Krishna Moku, Chandra Bhushan Mishra, Vasanthi Avadhanula, Pedro A. Piedra, and Yongcheng Song ACS Infectious Diseases 2023 DOI: 10.1021/acsinfecdis.3c00565 Highly contagious SARS-CoV-2 coronavirus has infected billions of people worldwide with flu-like symptoms since its emergence in 2019.

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NASA analysis confirms 2023 as warmest year on record

Science Daily: Pharmacology News

Earth's average surface temperature in 2023 was the warmest on record, according to an analysis by NASA. Global temperatures last year were around 2.1 degrees Fahrenheit (1.2 degrees Celsius) above the average for NASA's baseline period (1951-1980), scientists from NASA's Goddard Institute for Space Studies (GISS) in New York reported.

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New patent expiration for Acadia Pharms drug NUPLAZID

Drug Patent Watch

Annual Drug Patent Expirations for NUPLAZID Nuplazid is a drug marketed by Acadia Pharms Inc and is included in two NDAs. It is available from one supplier. There are fourteen… The post New patent expiration for Acadia Pharms drug NUPLAZID appeared first on DrugPatentWatch - Make Better Decisions.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Earth-sized planet discovered in 'our solar backyard'

Science Daily: Pharmacology News

Astronomers have discovered a planet closer and younger than any other Earth-sized world yet identified. It's a remarkably hot world whose proximity to our own planet and to a star like our sun mark it as a unique opportunity to study how planets evolve.

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New patent for Hisamitsu drug SECUADO

Drug Patent Watch

Annual Drug Patent Expirations for SECUADO Secuado is a drug marketed by Hisamitsu and is included in one NDA. It is available from one supplier. There are five patents protecting… The post New patent for Hisamitsu drug SECUADO appeared first on DrugPatentWatch - Make Better Decisions.

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New patent for Bristol drug AUGTYRO

Drug Patent Watch

Annual Drug Patent Expirations for AUGTYRO Augtyro is a drug marketed by Bristol and is included in one NDA. It is available from one supplier. The generic ingredient in AUGTYRO… The post New patent for Bristol drug AUGTYRO appeared first on DrugPatentWatch - Make Better Decisions.

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Unveiling the World of Universal Design

Perficient: Drug Development

Greetings, dear readers! Today marks the commencement of an exciting new series that delves into the realm of innovation, accessibility, and the pursuit of creating a world that embraces everyone. Our inaugural topic is one that forms the foundation of inclusive design – “Universal Design.” Join us on this journey as we unravel the principles, significance, and real-world applications of Universal Design, a philosophy that envisions a world where products, environments, and systems a

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New patent for Azurity drug EPRONTIA

Drug Patent Watch

Annual Drug Patent Expirations for EPRONTIA Eprontia is a drug marketed by Azurity and is included in one NDA. It is available from one supplier. There are two patents protecting… The post New patent for Azurity drug EPRONTIA appeared first on DrugPatentWatch - Make Better Decisions.

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New patent expiration for Cubist Pharms drug DIFICID

Drug Patent Watch

Annual Drug Patent Expirations for DIFICID Dificid is a drug marketed by Cubist Pharms Llc and is included in two NDAs. It is available from one supplier. There are six… The post New patent expiration for Cubist Pharms drug DIFICID appeared first on DrugPatentWatch - Make Better Decisions.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Which pharmaceutical companies have the most cream dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most cream dosed drugs. For a different perspective, see the most popular dosage types. The companies with the most cream dosed drugs… The post Which pharmaceutical companies have the most cream dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.