Thu.Oct 17, 2024

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Global carbon dioxide emissions from forest fires increase by 60 percent

Science Daily: Pharmacology News

A major new study reveals that carbon dioxide emissions from forest fires have surged by 60 percent globally since 2001, and almost tripled in some of the most climate-sensitive northern boreal forests.

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After rejections, AbbVie secures approval for Parkinson’s drug

BioPharma Drive: Drug Pricing

Vyalev’s clearance is the second victory for AbbVie in Parkinson’s this year, following an April readout for a drug acquired through its Cerevel buyout.

Drugs 131
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Why do we love carbs? The origins predate agriculture and maybe even our split from Neanderthals

Science Daily: Pharmacology News

A new study reveals how the duplication of the salivary amylase gene may not only have helped shape human adaptation to starchy foods, but may have occurred as far back as more than 800,000 years ago, long before the advent of farming.

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Listeria Recall Expands to Include Nearly 12 Million Pounds of Meat, Poultry

Drugs.com

THURSDAY, Oct. 17, 2024 -- A national recall of meat and poultry has been expanded to include close to 12 million pounds of products that may have been contaminated with listeria, U.S. health officials announced. In addition, the updated recall.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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New mRNA vaccine created to prevent and treat C. difficile

Science Daily: Pharmacology News

A new vaccine provides hope for treating and even preventing the highly contagious and difficult-to-treat Clostridioides difficile infection, more commonly known as C. difficile or C. diff. In animal models, this first mRNA-LNP C. difficile vaccine was found to protect against C. difficile first-time infections and relapsing infections by inducing a robust immune response, promote clearance of existing C. diff bacteria from the gut, and even overcome deficits in host immunity to protect animals

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The Right Time is Now to Get Your Flu Vaccine

Drugs.com

THURSDAY, Oct. 17, 2024 -- Folks who want solid protection during the cold and flu season should get the influenza vaccine now, the U.S. Food and Drug Administration says. The ideal time to get the flu vaccine is by the end of October, the FDA said.

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More Trending

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What's the Best Clot-Buster Med After Stroke?

Drugs.com

THURSDAY, Oct. 17, 2024 -- An off-label clot-busting drug appears to work slightly better in treating stroke patients than an approved medication, a new review finds. The clot-buster tenecteplase is associated with a slightly higher likelihood of.

Drugs 105
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Controlling prosthetic hands more precisely by the power of thought

Science Daily: Pharmacology News

Researchers have developed a novel training protocol for brain-computer interfaces in a study with rhesus monkeys. The method enables precise control of prosthetic hands using signals from the brain alone. Researchers were able to show that the neural signals that control the different hand postures in the brain are primarily important for this control, and not, as previously assumed, signals that control the movement's velocity.

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Sage to cut one-third of workforce, streamline drug pipeline

BioPharma Drive: Drug Pricing

The restructuring, which follows clinical setbacks in Alzheimer’s, Parkinson’s and tremor, will also involve the departure of five senior executives.

Drugs 111
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Concerning levels of PFAS in fish miles away from large contamination source

Science Daily: Pharmacology News

Fish can accumulate high levels of per- and polyfluoroalkyl substances (PFAS), even far from sources of contamination, according to a new study. The research highlights the need for expanded monitoring in watersheds affected by large PFAS sources, such as military bases across the country that have been contaminated by the use of PFAS-containing foams for fire-training and firefighting activities.

Research 109
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Sanofi, expanding in radiopharma, strikes a joint venture deal

BioPharma Drive: Drug Pricing

The French drugmaker will invest 300 million euros into a new entity that will develop lead isotope-based therapies for cancer under the Orano Med brand.

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Quantum research breakthrough uses synthetic dimensions to efficiently process quantum information

Science Daily: Pharmacology News

A new study opens the door to cutting-edge solutions that could contribute to the realization of a system capable of processing quantum information in a simple yet powerful way. The work presents a method for manipulating the photonic states of light in a never-before-seen way, offering greater control over the evolution of photon propagation. This control makes it possible to improve the detection and number of photon coincidences, as well as the efficiency of the system.

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Are Stroke Survivors Getting Too Many Sedatives Like Xanax, Valium?

Drugs.com

THURSDAY, Oct. 17, 2024 -- Doctors might be overprescribing sedatives to stroke survivors, a new study warns. About 5% of people are prescribed a benzodiazepine following a stroke, to help calm anxiety and improve sleep, researchers found.

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Scientists discover fastest degrading bioplastic in seawater

Science Daily: Pharmacology News

Scientists found that cellulose diacetate foam (CDA) is the fastest degrading bioplastic in an ocean environment. This new foam material is demonstrated to be a viable replacement for Styrofoam products and single-use plastics, like food packaging trays, as it achieves all the benefits of plastic but doesn't contribute to plastic pollution. This biodegradable bioplastic foam was evaluated in a flow-through seawater tank.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Silent Damage First: Alzheimer's Disease Could Have Two Phases

Drugs.com

THURSDAY, Oct. 17, 2024 -- Alzheimer’s disease might damage the brain in two distinct phases, a new study suggests. An early phase that occurs slowly and silently appears to lay the groundwork for a second, more widely destructive phase of.

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Engineers unveil breakthrough in ultra-clean biofuel technology

Science Daily: Pharmacology News

Researchers have unveiled a pioneering method for the efficient combustion of biofuels, using a revolutionary Swirl Burst (SB) injector to burn glycerol/methanol blends with near-zero emissions. This new technology enables ultra-clean combustion for fuels that are typically difficult to burn due to their high viscosity.

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Regulatory considerations for biosimilar analytical similarity assessments

Drug Patent Watch

Regulatory Considerations for Biosimilar Analytical Similarity Assessments Biosimilars, or follow-on biologics, are biopharmaceuticals that are highly similar to an already approved biological product.

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Plankton balloon to six times their size in newly discovered mode of oceanic travel

Science Daily: Pharmacology News

Many plankton journey from the cold, dark depths of our oceans to the surface, only to eventually drift down again into the darkness in a perpetual rhythm. Yet, how single-celled phytoplankton, most of which have no appendages to help them swim, make this pilgrimage has remained a mystery. Researchers now describe a species of bioluminescent phytoplankton, called Pyrocystis noctiluca, that balloons to six times their original size of a few hundred microns.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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New Drug Regimen Extends Survival for Cervical Cancer Patients

Drugs.com

THURSDAY, Oct. 17, 2024 -- In some good news for women battling locally advanced cervical cancer, new research shows that adding six weeks of chemotherapy to standard treatment cuts the risk of death by 40 percent. “This is the biggest.

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Microbiome: Drug discovery within the patient

Science Daily: Pharmacology News

Microorganisms do not just colonize the body of mammals during infections. Billions of microbes can be found on and in healthy humans and animals at any given time, communicating with each other via chemical signals and thus influencing their health. In two studies, researchers have now conducted a detailed study of the microbiome, i.e. the totality of all microorganisms, in humans and zoo animals.

Drugs 105
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Celebrating the 2024 Nobel Prize in Chemistry

addgene Blog

We’re big fans of all our depositors here at Addgene — your contributions make the repository what it is. So we’re thrilled this week to congratulate depositor David Baker , who was awarded the Nobel Prize in Chemistry last week alongside Demis Hassabis and John Jumper! The Baker Lab focuses on designing entirely new proteins, improving our understanding of how protein folding works and creating biological tools not found in nature.

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Harnessing vibrations: Engineered material generates electricity from unexpected source

Science Daily: Pharmacology News

Imagine tires that charge a vehicle as it drives, streetlights powered by the rumble of traffic, or skyscrapers that generate electricity as the buildings naturally sway and shudder. These energy innovations could be possible thanks to researchers developing environmentally friendly materials that produce electricity when compressed or exposed to vibrations.

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Weight-Loss Meds Like Wegovy, Ozempic Could Battle Alcoholism

Drugs.com

THURSDAY, Oct. 17, 2024 -- Weight-loss and diabetes drugs like Ozempic, Wegovy, Mounjaro or Zepbound appear to help people battle alcoholism and opioid addiction, a new study finds. People taking this class of drugs, called glucagon-like peptide-1.

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Astronomers detect ancient lonely quasars with murky origins

Science Daily: Pharmacology News

Astronomers observed ancient quasars that appear to be surprisingly alone in the early universe. The findings challenge physicists' understanding of how such luminous objects could have formed so early on in the universe, without a significant source of surrounding matter to fuel their growth.

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The Promise of a Direct-to-Patient Model—Breaking Down What’s Really Needed for Better Patient Access

Drug Channels

Today’s guest post comes from Greg Skalicky, President, EVERSANA and Faruk Abdullah, President, Professional Services & Chief Business Officer, EVERSANA Greg and Faruk walk through the marketplace pressures driving Direct-to-Patient commercialization models. They argue that a technology-enabled infrastructure, combined with clinical and reimbursement support specialists, can improve patients' access to new therapies, shorten the time to therapy, and enable better overall clinical outco

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Visible light energy yields two-for-one deal when added to CO2 recycling process

Science Daily: Pharmacology News

By combining visible light and electrochemistry, researchers have enhanced the conversion of carbon dioxide into valuable products and stumbled upon a surprising discovery. The team found that visible light significantly improved an important chemical attribute called selectivity, opening new avenues not only for CO2 conversion but also for many other chemical reactions used in catalysis research and chemical manufacturing.

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The Data-Driven Future of Drug Development

DrugBank

Data science has emerged as an innovative tool in the biopharmaceutical industry, leveraging the power of machine learning and artificial intelligence to drive innovation and efficiency across the entire drug development lifecycle. By harnessing the vast amounts of data generated throughout the development pipeline, pharmaceutical companies can accelerate the discovery of novel therapies, optimize clinical trial design, enhance drug safety monitoring, and deliver personalized medicine, ultimatel

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Life-saving spongelike 'bandage' rapidly stops hemorrhaging and mitigates risk of infection

Science Daily: Pharmacology News

Researchers created a liquid gel that quickly transforms into a spongelike antimicrobial foam to stymie severe bleeding and ultimately preserve lives.

Research 105
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New diagnostic approach for bacterial infections shows promise in the clinic

Broad Institute

New diagnostic approach for bacterial infections shows promise in the clinic By Leah Eisenstadt October 17, 2024 Breadcrumb Home New diagnostic approach for bacterial infections shows promise in the clinic In a pilot study with patient samples, the technology performed as well as the current gold-standard methods, yielding accurate results within hours instead of days.

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Forever Chemicals found in bottled and tap water from around the world

Science Daily: Pharmacology News

Scientists have discovered toxic 'Forever Chemicals' present in samples of drinking water from around the world.

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Vaping Rates Hit Record Lows for U.S. High School Students

Drugs.com

THURSDAY, Oct. 17, 2024 -- Is vaping finally losing its coolness for American teens? The latest tally of federal data finds that 550,000 school kids, mostly high schoolers, quit using e-cigarettes in 2024. Vaping rates fell from 10% of high school.

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Identifying the genes that viruses 'steal' from ocean microbes

Science Daily: Pharmacology News

A new study gets scientists closer to more fully understanding where viruses fit into the global ocean picture of cycling nutrients such as nitrogen, phosphorus and, of particular interest, carbon. Researchers report on their creation of a catalog of genes that viruses 'stole' from the marine microbes they infected across all of the world's oceans, identifying and organizing almost 23,000 genes known as auxiliary metabolic genes (AMGs), including over 7,000 never previously documented.

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Perficient Scores Three Top Workplaces Culture Excellence Awards

Perficient: Drug Development

Awards Recognize Perficient for Prioritizing a People-First Mindset and Workplace Experience We’re thrilled to share that Perficient has been recognized by Energage and Nectar with three 2024 Top Workplaces Culture Excellence Awards : Professional Development Top Workplaces, Top Workplaces for Appreciation, and Employee Well-Being Top Workplaces! This recognition underscores our unwavering commitment to fostering a world-class culture that challenges, champions, and celebrates our people.

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