Tue.Jan 02, 2024

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Conversations from Cancer Research Horizons’ Innovation Summit 2023 

Drug Discovery World

Cancer Research Horizon’s Innovation Summit 2023 took place on 21 November 2023 at the Royal Society of Medicine, and included talks from researchers translating their research, as well as networking with members of the entrepreneurial ecosystem. DDW’s Megan Thomas spoke to a range of attendees. Trends for cancer research Dr Alessia Errico, is a technology transfer professional, specialised in the field of oncology, and the Associate Director for Search & Evaluation at Cancer Research

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Evolution might stop humans from solving climate change

Science Daily: Pharmacology News

Human culture has evolved to allow humans to extract resources and helped us expand to dominate the biosphere. But the same evolutionary processes may counteract efforts to solve new global environmental threats like climate change, according to a new study. Tackling the climate crisis will require worldwide regulatory, technical and economic systems supported by strong global cooperation.

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Do JAK inhibitors increase the risk of serious adverse events?

Drug Discovery World

South Korean researchers have found that the use of Janus kinase (JAK) inhibitors as a treatment for atopic dermatitis (AD) is not associated with a greater risk of serious adverse events. While several biologic treatment approaches have been proposed in the recent years for the treatment of AD, they often fall short of providing the required care in relieving symptoms of moderate-to-severe AD.

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New study from the RVC explores malaria invasion to help develop life-saving vaccine

Drug Discovery Today

Researchers from the Royal Veterinary College (RVC) and University of Oxford have led an innovative project investigating the progression of malaria infection and the role of the parasite to better aid the development of an effective malaria vaccine and significantly reduce rates of deaths from the disease.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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10 clinical trials to watch in the first half of 2024

BioPharma Drive: Drug Pricing

A non-addictive pain pill faces its definitive test, while study results in ALS, a rare heart disease and lung cancer could have far-reaching implications.

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More Americans Will Only Have to Pay $35 a Month for Insulin in 2024

Drugs.com

TUESDAY, Jan. 2, 2024 -- Managing diabetes will be a less expensive proposition for more Americans in 2024.Sanofi has officially joined Novo Nordisk and Eli Lilly in lowering the cost of insulin to $35 a month for many patients. The three.

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FDA ends busy year with three drug rejections

BioPharma Drive: Drug Pricing

Amgen had its bid for full approval of the cancer drug Lumakras turned back by the agency, which also issued complete response letters to Zealand Pharma and Merck & Co. in December.

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Ants recognize infected wounds and treat them with antibiotics

Science Daily: Pharmacology News

The African Matabele ants are often injured in fights with termites. Their conspecifics recognize when the wounds become infected and initiate antibiotic treatment.

Treatment 120
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Talk of the Towne episode 09: BrightFocus Foundation

Antidote

The latest episode of Antidote’s quarterly podcast series Talk of the Towne is available now! Talk of the Towne is focused on bridging the gap between clinical discussion and patient centricity, hosted by Antidote’s Senior Clinical Informatics Manager, Dr. Richard Towne, PharmD.

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'Juvenile T. rex' fossils are a distinct species of small tyrannosaur

Science Daily: Pharmacology News

A new analysis of fossils believed to be juveniles of T. rex now shows they were adults of a small tyrannosaur, with narrower jaws, longer legs, and bigger arms than T. rex. The species, Nanotyrannus lancensis, was first named decades ago but later reinterpreted as a young T. rex. The new study shows Nanotyrannus was a smaller, longer-armed relative of T. rex, with a narrower snout.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Know the Facts About Glaucoma

Drugs.com

TUESDAY, Jan. 2, 2024 -- Glaucoma can steal your sight before you even realize it, and early diagnosis is the best way to prevent it.Many of the 3 million Americans who have glaucoma are unaware of it because they have no symptoms, according to the.

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What the Minnesota Timberwolves Coach Chris Finch and Perficient’s Envision Framework Have In Common

Perficient: Drug Development

Being an avid basketball fan, I have enjoyed watching the Minnesota Timberwolves ’ success on the court to begin the 2023-2024 season. And being the basketball geek that I am, I did research to find out what the Timberwolves have done differently this season compared to other seasons that have helped them vault up to the top of the standings through the first month and a half of play.

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Webinar: Accelerating Large-Scale Genomics Research

Nvidia Developer: Drug Discovery

Learn how the Francis Crick Institute is using NVIDIA Clara Parabricks to enable key parts of TRACERx EVO, a new program that builds on the discoveries made in. Learn how the Francis Crick Institute is using NVIDIA Clara Parabricks to enable key parts of TRACERx EVO, a new program that builds on the discoveries made in the world’s largest long-term lung study.

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Living With a Depressed Loved One Can Take Mental, Financial Toll

Drugs.com

TUESDAY, Jan. 2, 2024 -- Reduced income, unemployment and mental health issues are more common among people who live with a loved one diagnosed with depression, new research shows.“These findings indicate that the impact of depressive symptoms.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Is oxygen the cosmic key to alien technology?

Science Daily: Pharmacology News

Astrophysicists outline the links between atmospheric oxygen and the potential rise of advanced technology on distant planets.

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Regret After Gender-Affirming Surgery Is Largely a Myth, Experts Say

Drugs.com

TUESDAY, Jan. 2, 2024 — Despite a common belief in the medical community and elsewhere, the vast majority of people who undergo gender-affirming surgery do not regret it later.In all, less than 1% of people who underwent gender-affirming surgery.

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Healthy omega-3 fats may slow deadly pulmonary fibrosis, research suggests

SCIENMAG: Medicine & Health

Could healthy fats found in nuts and fish slow the progression of potentially deadly lung scarring known as pulmonary fibrosis and delay the need for lung transplants?

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From NYC to DC and beyond, cities on the East Coast are sinking

Science Daily: Pharmacology News

Major cities on the U.S. Atlantic coast are sinking, in some cases as much as 5 millimeters per year -- a decline at the ocean's edge that well outpaces global sea level rise, confirms new research. Particularly hard hit population centers such as New York City and Long Island, Baltimore, and Virginia Beach and Norfolk are seeing areas of rapid 'subsidence,' or sinking land, alongside more slowly sinking or relatively stable ground, increasing the risk to roadways, runways, building foundations,

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Memory, brain function, and behavior: exploring the intricate connection through fear memories

SCIENMAG: Medicine & Health

In a world grappling with the complexities of mental health conditions like anxiety, depression, and PTSD, new research from Boston University neuroscientist Dr. Steve Ramirez and collaborators offers a unique perspective. The study, recently published in the Journal of Neuroscience, delves into the intricate relationship between fear memories, brain function, and behavioral responses.

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Researchers identify new coding mechanism that transfers information from perception to memory

Science Daily: Pharmacology News

Our memories are rich in detail: we can vividly recall the color of our home, the layout of our kitchen, or the front of our favorite cafe. How the brain encodes this information has long puzzled neuroscientists.

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Uncovering How Tiny Plastics Threaten Our Soil and Health

SCIENMAG: Medicine & Health

The widespread presence of tiny plastics, known as microplastics and nanoplastics, in our environment is raising alarm. These particles, coming from various sources like industrial waste or larger plastic breakdown, are increasingly found in water, soil, and air.

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Defibrillators Now Mandatory at Some Gyms, Stadiums -- Why Aren't More People Using Them?

Drugs.com

TUESDAY, Jan. 2, 2024 -- Because athletes young and old can suffer cardiac arrest, some states have mandated the placement of automated external defibrillators (AEDs) in gyms, stadiums and other sports venues.But a new study finds the use of AEDs.

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Enlarged spaces in infant brains linked to higher risk of autism, sleep problems

SCIENMAG: Medicine & Health

Throughout the day and night, cerebrospinal fluid (CSF) pulses through small fluid-filled channels surrounding blood vessels in the brain, called perivascular spaces, to flush out neuroinflammation and other neurological waste. A disruption to this vital process can lead to neurological dysfunction, cognitive decline, or developmental delays.

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Tome acquires startup Replace, gaining new genome editing tools

BioPharma Drive: Drug Pricing

The deal is the second startup sale engineered by University of California, Berkeley scientist Shakked Halperin, and gives Tome a way to insert or delete small DNA sequences into the genome.

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Demystifying a key receptor in substance use and neuropsychiatric disorders

SCIENMAG: Medicine & Health

New York, NY (January 2, 2024)—Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric disorders. This discovery may pave the way for the development of improved medications targeting the same pathway.

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Novartis deepens ties with Voyager via $100M gene therapy deal

BioPharma Drive: Drug Pricing

The deal builds on an existing alliance and includes tools Novartis will use in gene therapies for Huntington’s disease and spinal muscular atrophy.

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New patent for Axsome Malta drug SUNOSI

Drug Patent Watch

Annual Drug Patent Expirations for SUNOSI Sunosi is a drug marketed by Axsome Malta and is included in one NDA. It is available from two suppliers. There are eighteen patents… The post New patent for Axsome Malta drug SUNOSI appeared first on DrugPatentWatch - Make Better Decisions.

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Citrus Supplement, Diosmin, Could Ease Swelling After Knee Replacement

Drugs.com

TUESDAY, Jan. 2, 2024 -- A diet supplement derived from citrus fruits reduced swelling and pain after knee replacement surgery, a new clinical trial found. The flavonoid supplement, diosmin, could offer a new approach to painful swelling after the.

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Unlocking the Power of Java Streams: Simplifying Code with Efficiency

Perficient: Drug Development

Overview of Java Streams Java introduced streams in version 8 to simplify and optimize code writing. A stream is a sequence of objects supporting various methods to achieve a desired result. Using streams can reduce a long set of codes to just a few lines. Streams enable performing operations such as filtering, mapping, reducing, and sorting. These operations drastically reduce code complexity.

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'Substantial Demand' for Abortion Pills Ordered in Advance, Study Finds

Drugs.com

TUESDAY, Jan. 2, 2024 -- A U.S. online provider of the mifepristone/misoprostol abortion pill combo saw a ten-fold jump in orders when the Dobbs decision overturning Roe v. Wade was first leaked in 2022, a new study finds.Such orders declined a bit.

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Seamless Collaboration: Elevating Testing Efficiency with Katalon Studio-JIRA Integration

Perficient: Drug Development

Katalon Studio stands as a robust and user-friendly test automation solution, designed to meet the evolving needs of software testing. Offering a comprehensive suite of features, Katalon Studio empowers testers to efficiently create, execute, and manage automated tests across web and mobile applications JIRA is a leading project management and issue-tracking tool renowned for its versatility and adaptability.

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Tips From an Expert as You Start 'Dry January'

Drugs.com

TUESDAY, Jan. 2, 2024 -- Many folks’ New Year resolutions include having a Dry January, and that’s a wise move, experts say.Taking even a one-month break from booze can lead to significant improvements in physical and mental health, said.

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5 Tips To Ease the Find Care Experience for Patients and Members

Perficient: Drug Development

Consumers across every age group expect healthcare digital experiences that match the ease and convenience of making purchases online, reserving a restaurant, booking private accommodations, getting personalized movie recommendations, filing taxes, and even virtually buying a car. However, the consumer-patient journey is far more complex and multifaceted than other everyday consumer experiences.

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Citrus Supplement Could Ease Swelling After Knee Replacement

Drugs.com

TUESDAY, Jan. 2, 2024 -- A diet supplement derived from citrus fruits reduced swelling and pain after knee replacement surgery, a new clinical trial found.The flavonoid supplement, diosmin, could offer a new approach to painful swelling after the.