Drug Discovery World
MAY 1, 2024
Oxford University spin-out Infinitopes Precision Immunomics has completed a £12.8 ($16) million seed funding round led by Octopus Ventures. The round was heavily oversubscribed, also drawing in funds from Cancer Research Horizons, Cancer Research Institute, CRIS Cancer Foundation, Kindred Capital, Manta Ray, Martlet Capital, Meltwind Advisory, Saras Capital, Wilbe Capital, and expert angel investors.
Science Daily: Pharmacology News
MAY 1, 2024
The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought. In a study on rats, a team of scientists has found that physical activity causes many cellular and molecular changes in all 19 of the organs they studied in the animals.
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Drug Discovery World
MAY 1, 2024
DDW’s Megan Thomas speaks to industry experts and thought leaders about the potential for therapeutic antibodies in 2024. Many of the best-selling drugs in 2023 were monoclonal antibody (mAB) therapies, including Keytruda (pembrolizumab), Humira (adalimumab), and Dupixent (dupilumab) 1. This won’t come as a surprise when you look at industry milestones achieved in 2023 and looking ahead, this shows no signs of slowing down.
Science Daily: Pharmacology News
MAY 1, 2024
A research team using the ChemCam instrument onboard NASA's Curiosity rover discovered higher-than-usual amounts of manganese in lakebed rocks within Gale Crater on Mars, which indicates that the sediments were formed in a river, delta, or near the shoreline of an ancient lake.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
MAY 1, 2024
A drop in the prices of non-human primates (NHPs) in China indicates a post-pandemic slowdown in Chinese drug development, according to a report in the Financial Times. The price of NHPs in China increased from $4,000 per animal in 2019 to $26,000 in 2022, but by the end of 2023, had fallen to $11,000. The figures are taken from UBS data. UBS China healthcare analyst Chen Chen said the price increase was due to “booming investment” in drug discovery in the first two years of the Covid-19 pandemi
Science Daily: Pharmacology News
MAY 1, 2024
With recent studies having established the presence of nano and microplastic particles in the respiratory systems of both human and bird populations, new research has modeled what happens when people breathe in different kinds of plastic particles and where they end up.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
MAY 1, 2024
Scientists are harnessing cells to make new types of materials that can grow, repair themselves and even respond to their environment. These solid 'engineered living materials' are made by embedding cells in an inanimate matrix that's formed in a desired shape. Now, researchers have 3D printed a bioink containing plant cells that were then genetically modified, producing programmable materials.
BioPharma Drive: Drug Pricing
MAY 1, 2024
Sales of the shingles vaccine Shingrix and the RSV shot Arexvy helped fuel quarterly revenue totals that surpassed analyst expectations, though the company warned momentum could slow in the months ahead.
Science Daily: Pharmacology News
MAY 1, 2024
The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in mice.
Drugs.com
MAY 1, 2024
WEDNESDAY, May 1, 2024 -- Hormone replacement therapy can safely ease middle-aged women’s symptoms during early menopause, data from a major women’s health study show. Women younger than 60 can use hormone replacement to treat symptoms.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
MAY 1, 2024
The body clock has a significant impact on the performance of NBA players. Data shows vastly better win ratio for home teams from the Western Time Zone Area (PDT) when playing an EDT team, compared to vice versa.
Drugs.com
MAY 1, 2024
WEDNESDAY, May 1, 2024 -- People drinking raw unpasteurized milk are at risk for potentially contracting bird flu, the U.S. Food and Drug Administration warned Wednesday.“We continue to strongly advise against the consumption of raw milk,” Dr.
BioPharma Drive: Drug Pricing
MAY 1, 2024
The move broadens the antitrust regulator’s campaign against allegedly “improper or inaccurate” patent listings by drugmakers to include top-selling medicines for weight loss, diabetes, asthma and COPD.
Science Daily: Pharmacology News
MAY 1, 2024
An experimental influenza vaccine carrying more than 80,000 variations of hemagglutinin antigens caused the immune system of mice and ferrets to respond more strongly to less variable portions of the virus. This is a big step forward in efforts at the Duke Human Vaccine Institute to develop a universal, long-lasting flu shot.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
MAY 1, 2024
Sales of the transthyretin amyloidosis treatment widely beat Wall Street forecasts in the first quarter. The company aims to extend its patent exclusivity.
Science Daily: Pharmacology News
MAY 1, 2024
During sleep, the brain weakens the new connections between neurons that had been forged while awake -- but only during the first half of a night's sleep, according to a new study.
Perficient: Drug Development
MAY 1, 2024
We are proud to announce Perficient has been awarded HCL Software’s Gold Reseller Award! This award comes as recognition for our continued collaboration and outstanding performance in regard to sales and delivery in 2023. As an HCL Software strategic partner, we actively drive innovation into HCL’s roadmap and collaborate closely from a product innovation and support perspective.
Science Daily: Pharmacology News
MAY 1, 2024
A new documentary has recreated the face of a 75,000-year-old female Neanderthal whose flattened skull was discovered and rebuilt from hundreds of bone fragments by a team of archaeologists and conservators.
Drugs.com
MAY 1, 2024
WEDNESDAY, May 1, 2024 -- In yet another sign that bird flu is spreading widely among mammals, a new report finds more than half of cats at the first Texas dairy farm to have cows test positive for bird flu this spring died after drinking raw.
Science Daily: Pharmacology News
MAY 1, 2024
Researchers have discovered a potential 'cosmic glitch' in the universe's gravity, explaining its strange behavior on a cosmic scale.
Drugs.com
MAY 1, 2024
WEDNESDAY, May 1, 2024 -- Feeling angry constricts blood vessels in unhealthy ways and could raise a person's long-term odds for heart disease, new research warns.“If you’re a person who gets angry all the time, you’re having chronic injuries.
Science Daily: Pharmacology News
MAY 1, 2024
Researchers have provided new age estimates and revised provenance information for the Liujiang human fossils, shedding light on the presence of Homo sapiens in the region. Using advanced dating techniques including U-series dating on human fossils, and radiocarbon and optically stimulated luminescence dating on fossil-bearing sediments, the study revealed new ages ranging from approximately 33,000 to 23,000 years ago.
Drugs.com
MAY 1, 2024
WEDNESDAY, May 1, 2024 -- Organic walnuts from a California grower that were distributed to health food and co-op stores in 19 states have been linked to serious cases of E. coli illness, federal officials reported Tuesday.So far, 12 people have.
NIOSH Science Blog: Drugs
MAY 1, 2024
The Current Situation with Falls In 2022 falls from elevation represented approximately 81% of all fatal and 20% of all nonfatal slips, trips, and falls for all industry workers (BLS 2023a, BLS 2023b). Many of these falls occurred in the construction industry, and significantly impact construction employers, workers, and their families. In fact, construction workers made up nearly half (49%) of all fatal occupational slips, trips, and falls (BLS 2023).
Drugs.com
MAY 1, 2024
WEDNESDAY, May 1, 2024 -- A toxin found in paint strippers that's responsible for 85 U.S. deaths over the past five decades will be phased out for many uses, under an Environmental Protection Agency rule finalized Tuesday. The cancer-causing.
Perficient: Drug Development
MAY 1, 2024
That was a decent gap since 1.5 years ago Sitecore previously released a feature-full version of their XM/XP platform, namely 10.3 was released on December 1st of 2022. That is why I was very excited to look through the newest release of the vendor’s self-hosted platforms and familiarize myself with its changes. First and foremost, the 10.4 platforms could be exclusively obtained from a new download page which has moved to its new home at Sitecore Developer Portal.
Drugs.com
MAY 1, 2024
WEDNESDAY, May 1, 2024 -- Women approaching menopause appear to be at higher risk of depression, a new review indicates.
Drug Target Review
MAY 1, 2024
How have advancements in antibody-drug conjugates (ADCs) expanded treatment options for different types of cancer? The design of ADCs has advanced considerably since initial efforts in the 1980’s, when using polyclonal antibodies and unoptimised payloads, linkers and conjugation strategies failed to provide patient benefit. The advent of monoclonal antibodies paired with improvements in each ADC design component has led to the approval of 11 ADCs with more than 180 ADCs currently in clinical dev
BioPharma Drive: Drug Pricing
MAY 1, 2024
The partnership follows Astellas’ investment in the biotech last year and adds to its portfolio of donor-derived cellular medicines.
Science Daily: Pharmacology News
MAY 1, 2024
Conventional plant regeneration approaches by cell culture require the external application of plant growth regulators, including hormones. However, optimizing culture conditions can be laborious. Now, researchers have developed a novel plant regeneration system that omits the need for hormone application by genetically regulating the expression of genes that control plant cell differentiation.
Drugs.com
MAY 1, 2024
WEDNESDAY, May 1, 2024 -- Getting the HPV shot in adolescence can spare kids a lifetime of risk for cervical and other cancers related to the virus, but only half of American kids are up-to-date on these shots.Now, a new review suggests that if.
Perficient: Drug Development
MAY 1, 2024
As of mid-February 2024, the Spring ‘24 release was generally available across all instances of Health Cloud bringing with it a host of improvements and added functionality for healthcare organizations. The new features and enhancements offer opportunities for efficiency, security, and insights. Home Health Advanced visit scheduling enables healthcare organizations to proactively manage care delivery, optimizing resource allocation and enhancing patient outcomes.
Drug Patent Watch
MAY 1, 2024
Annual Drug Patent Expirations for NEXTSTELLIS Nextstellis is a drug marketed by Mayne Pharma and is included in one NDA. It is available from one supplier.
Fierce BioTech
MAY 1, 2024
New modality - Peptides Innovations and A Comprehensive Synthetic Peptide Drug Discovery Platform dwunderlin Wed, 05/01/2024 - 17:28 Wed, 06/19/2024 - 10:00 Resource Type Webinar Yuyan Chen Wanyong Feng Jingjing Zhu Promotion Start Thu, 05/02/2024 - 16:00 Promotion End Sat, 11/02/2024 - 16:00 Duration 60 Minutes Peptides emerge as a new promising modality in different area, such as GLP-1 analogues, PDC, PPI inhibitors etc.
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