Drug Discovery World

JULY 17, 2024

The US Food and Drug Administration (FDA) has granted Regenerative Medicine Advanced Therapy (RMAT) designation to Kyverna Therapeutic’s CAR-T candidate KYV-101 for refractory stiff-person syndrome (SPS). KYV-101 is an autologous, fully human CD19 CAR-T cell product candidate for use in B cell-driven autoimmune diseases. The RMAT designation was based on positive clinical outcomes in patients treated in Germany under a named-patient treatment option.

Therapies 130

Therapies FDA Trials Treatment 130

Science Daily: Pharmacology News

JULY 17, 2024

Have you ever wondered how insects are able to go so far beyond their home and still find their way? The answer to this question is not only relevant to biology but also to making the AI for tiny, autonomous robots. Drone-researchers felt inspired by biological findings on how ants visually recognize their environment and combine it with counting their steps in order to get safely back home.

Research 136

Research 136

Drug Discovery World

JULY 17, 2024

A drug commonly used to treat cystic fibrosis improved outcomes for patients with severe Covid-19 pneumonia in a recent clinical trial. The drug, dornase alfa, could be used to treat other respiratory infections, according to the data from researchers at UCL, UCLH and the Francis Crick Institute. The study found that dornase alfa reduced hyper-inflammation in Covid-19 pneumonia patients, which occurs when the body’s immune system reacts too strongly and can lead to tissue damage and death.

Clinical Trials 130

Clinical Trials Drugs Hospitals Trials 130

Science Daily: Pharmacology News

JULY 17, 2024

Researchers report that psilocybin, the active ingredient in magic mushrooms, destabilizes a critical network of brain areas involved in introspective thinking. The findings provide a neurobiological explanation for the drug's mind-bending effects.

Research 122

Research Drugs 122

Advertisement

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

JULY 17, 2024

WEDNESDAY, July 17, 2024 (HeathDay News) -- Sleeping long hours one night but only a few hours the next can be unhealthy, with a new study finding "irregular" sleep patterns could be a risk factor for type 2 diabetes.The results "underscore the.

115

115

Science Daily: Pharmacology News

JULY 17, 2024

Researchers have demonstrated that the layered multiferroic material nickel iodide (NiI2) may be the best candidate yet for devices such as magnetic computer memory that are extremely fast and compact. Specifically, they found that NiI2 has greater magnetoelectric coupling than any known material of its kind.

Research 116

Research 116

Science Daily: Pharmacology News

JULY 17, 2024

An environmental engineering team has discovered that specific bacterial species can cleave the strong fluorine-to-carbon bond certain kinds of 'forever chemical' water pollutants, offering promise for low-cost treatments of contaminated drinking water.

Engineering 116

Engineering Treatment 116

Drugs.com

JULY 17, 2024

WEDNESDAY, July 17, 2024 -- Just two years after the launch of the nation's three-digit crisis hotline, more than 10 million calls, texts and chat messages have been fielded by counselors, U.S. health officials announced Tuesday. Introduced in July.

105

105

Science Daily: Pharmacology News

JULY 17, 2024

High-protein diets, known as 'Paleolithic diets', are popular. Using mouse models, scientists have studied their impact. While effective in regulating weight and stabilizing diabetes, these diets are not without risks. Excess protein greatly increases ammonium production, overwhelming the liver. Excess ammonium can cause neurological disorders and, in severe cases, lead to coma.

Regulations 115

Regulations Production 115

Drugs.com

JULY 17, 2024

WEDNESDAY, July 17, 29024 -- In a joint effort to curb the illegal sales of food products containing delta-8 THC, the U.S. Food and Drug Administration and the Federal Trade Commission said Tuesday they have warned five companies to stop marketing.

Production 105

Production Marketing Drugs 105

Advertisement

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Science Daily: Pharmacology News

JULY 17, 2024

Researchers have established new criteria for a memory-loss syndrome in older adults that specifically impacts the brain's limbic system. It can often be mistaken for Alzheimer's disease.

Disease 113

Disease Research 113

BioPharma Drive: Drug Pricing

JULY 17, 2024

Jefferies analyst Andrew Tsai views growing sales for J&J’s depression treatment as evidence that psychedelics like it can be commercially viable.

Treatment 114

Treatment Drugs 114

Science Daily: Pharmacology News

JULY 17, 2024

Biology researchers have developed a new antibody therapy that can neutralize a wide variety of HIV-1 strains. They found success in an unlikely source -- llamas.

Therapies 118

Therapies Research 118

Drugs.com

JULY 17, 2024

WEDNESDAY, July 17, 2024 -- Autopsies of deceased boxers and pro football players have long confirmed that repeat head injuries can lead to a devastating brain condition known as chronic traumatic encephalopathy (CTE).Now, research supports the.

Research 98

Research 98

Advertisement

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

JULY 17, 2024

In an era when the creation of artificial intelligence (AI) images is at the fingertips of the masses, the ability to detect fake pictures -- particularly deepfakes of people -- is becoming increasingly important. So what if you could tell just by looking into someone's eyes? That's the compelling finding of new research which suggests that AI-generated fakes can be spotted by analyzing human eyes in the same way that astronomers study pictures of galaxies.

Research 112

Research 112

Drugs.com

JULY 17, 2024

WEDNESDAY, July 17, 2024 -- Defiance, tantrums, aggression: All signs of a condition called conduct disorder, which Mental Health America says affects up to 16% of boys and 9% of girls.Now, research is revealing real differences in the brain.

Research 98

Research 98

Science Daily: Pharmacology News

JULY 17, 2024

Cut marks on fossils could be evidence of humans exploiting large mammals in Argentina more than 20,000 years ago, according to a new study.

128

128

Drugs.com

JULY 17, 2024

WEDNESDAY, July 17, 2024 -- Most salmonella outbreaks linked to poultry are caused by just a few strains of the diarrhea-causing bacteria, a new study finds.There are more than 2,600 different types of salmonella bacteria, but only three strains.

98

98

Science Daily: Pharmacology News

JULY 17, 2024

A new gene therapy treatment for Duchenne muscular dystrophy (DMD) shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those muscles. The research focuses on delivering a series of protein packets inside shuttle vectors to replace the defective DMD gene within the muscles.The gene for dystrophin is one of the largest in the human genome, and is difficult to fit inside a delivery shuttle.

Therapies 110

Therapies Treatment Disease Research 110

Drug Patent Watch

JULY 17, 2024

The High Stakes of Pharmaceutical Patent Litigation In the fiercely competitive pharmaceutical industry, patent disputes can make or break a […] Source

Pharmaceutical Companies 105

Pharmaceutical Companies Pharmaceuticals Drugs 105

Science Daily: Pharmacology News

JULY 17, 2024

Researchers have developed soft, stretchable 'jelly batteries' that could be used for wearable devices or soft robotics, or even implanted in the brain to deliver drugs or treat conditions such as epilepsy.

Research 107

Research Drugs 107

Drugs.com

JULY 17, 2024

WEDNESDAY, July 17, 2024 -- Exercise near bedtime won’t necessarily wreck a person’s sleep, a new study says.Intense exercise is typically discouraged as bedtime approaches, since such activity can disturb sleep by increasing body temperature and he.

96

96

Science Daily: Pharmacology News

JULY 17, 2024

New research has examined the fossil record going back 66 million years and tracked changes to mammalian ecosystems and species diversity on the North American continent.

Research 109

Research 109

Drugs.com

JULY 17, 2024

WEDNESDAY, July 17, 2024 -- It's a little known health condition that can become a nightmare: Regular and sudden episodes of intense nausea and vomiting.Now, new clinical guidance urges people to take notes and speak up if they think they have the.

95

95

Science Daily: Pharmacology News

JULY 17, 2024

Cobras kill thousands of people a year worldwide and current antivenom treatment is expensive and does not effectively treat the necrosis of the flesh where the bite occurs. Using CRISPR technology, scientists have discovered a commonly available drug can stop the necrosis, potentially saving thousands of lives a year.

Treatment 105

Treatment Drugs 105

Drugs.com

JULY 17, 2024

WEDNESDAY, July 17, 2024 -- Many couples may be painfully familiar with the scenario: One partner snores loudly all night long, so the other partner seeks better sleep in another bed.Now, a new survey from the American Academy of Sleep Medicine.

95

95

Science Daily: Pharmacology News

JULY 17, 2024

Scientists have discovered that 'switching off' a protein called IL-11 can significantly increase the healthy lifespan of mice by almost 25 percent.

112

112

Codon

JULY 17, 2024

In a quiet New York town, an amateur scientist has constructed a fully equipped research laboratory in which to advance plant biology research. Sebastian Cocioba wears the word “amateur” as a badge of honor. He’s an educator, molecular florist, and founder at Binomica Labs , a small biology research group focusing on providing an alternative to “exposure-driven and marketing-centric research.” Earlier this year, we sent a photographer to Sebastian’s home labor

Laboratories 94

Laboratories Engineering Molecular Biology Science 94

Science Daily: Pharmacology News

JULY 17, 2024

Despite facing regional threats like deforestation and wildfires, the world's forests continue to be a powerful weapon in the fight against climate change. A new study reveals these vital ecosystems have consistently absorbed carbon dioxide for the past three decades, even as disruptions chip away at their capacity. The study, based on long-term ground measurements combined with remote sensing data, found that forests take up an average of 3.5 0.4 billion metric tons of carbon per year, which is

95

95

Drugs.com

JULY 17, 2024

WEDNESDAY, July 17, 2024 -- Bicycling to work can vastly improve your health and reduce your risk of death, a new study shows.People who bike commute have a 47% lower overall risk of an early death, researchers found.They also are less likely to.

Research 93

Research 93

Broad Institute

JULY 17, 2024

De-risking drug discovery with predictive AI By Tom Ulrich July 17, 2024 Breadcrumb Home De-risking drug discovery with predictive AI A suite of new machine learning models can estimate the safety of potential new drugs By Claire Hendershot July 17, 2024 Related programs Imaging Platform Developing a new drug can take years of research and cost millions of dollars.

Pharmacokinetics 84

Pharmacokinetics Molecular Biology Drugs FDA 84

Science Daily: Pharmacology News

JULY 17, 2024

The newly discovered planet TIC 241249530 b has the most highly elliptical, or eccentric, orbit of any known planet. It appears to be a juvenile planet that is in the midst of becoming a hot Jupiter, and its orbit is providing some answers to how such large, scorching planets evolve.

79

79

BioPharma Drive: Drug Pricing

JULY 17, 2024

Merdad Parsey joined Gilead as its chief medical officer in 2019 and has helped lead the company’s expansion into oncology, with mixed success.

69

69

Perficient: Drug Development

JULY 17, 2024

In our latest episode of “What If? So What?”, we dive deep into the world of semiconductors and the cutting-edge innovations being made at Intel. Host Jim Hertzfeld sits down with Carolyn Henry, vice president and general manager of America’s regional marketing at Intel, to explore the indispensable role of semiconductors in our daily lives.

Marketing 59

Marketing Production 59