Mon.Jul 01, 2024

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Proscia teams up with Nucleai to improve access to AI biomarkers

Drug Discovery World

Software company Proscia has partnered with spatial AI biomarker company Nucleai in a collaboration aimed at improving precision medicine biomarkers for clinical trials. The companies are integrating Nucleai’s predictive biomarker solutions into Proscia’s Concentriq software platform and will make them available as part of Proscia’s precision medicine AI portfolio.

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New and improved camera inspired by the human eye

Science Daily: Pharmacology News

Computer scientists have invented a camera mechanism that improves how robots see and react to the world around them. Inspired by how the human eye works, their innovative camera system mimics the tiny involuntary movements used by the eye to maintain clear and stable vision over time.

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CatSci acquires chromatography provider Reach Separations

Drug Discovery World

CatSci has acquired Reach Separations, a specialist chromatography provider for the analysis and purification of therapeutics. The acquisition was supported by Keensight Capital, private equity managers dedicated to pan-European Growth Buyout investments. Headquartered in the UK, and with laboratories in both the UK and France, Reach Separations specialises in chromatography for the analysis and purification of chiral and achiral therapeutics.

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All Diamond Shruumz Edibles Recalled Over High Levels of Mushroom Toxin in Products

Drugs.com

MONDAY, July 1, 2024 -- All Diamond Shruumz edibles have been recalled after the company found high levels of a mushroom toxin in them that may have sickened 39 people in 20 states.The recall includes Diamond Shruumz cones, chocolate bars and.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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From cradle to grave: Novo Nordisk Foundation and cardiometabolic diseases 

Drug Discovery World

Following a trip to Copenhagen, Denmark, DDW’s Megan Thomas reflects on the Novo Nordisk Foundation’s efforts to tackle cardiometabolic diseases. According to presentations given at the Foundation’s HQ, more than 30% of the world’s population is overweight or obese and 537 million people live with diabetes. The World Health Organization (WHO) reports that cardiovascular diseases (CVDs) are the leading cause of death globally, stating that an estimated 17.9 million people died from CVDs in 2019

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Organic material from Mars reveals the likely origin of life's building blocks

Science Daily: Pharmacology News

Two samples from Mars together deliver clear evidence of the origin of Martian organic material. The study presents solid evidence for a prediction made over a decade ago that could be key to understanding how organic molecules, the foundation of life, were first formed here on Earth.

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Common Chemo Drug, Cisplatin, May Be Linked to Hearing Loss

Drugs.com

MONDAY, July 1, 2024 (HealthDay news) -- A 14-year study of testicular cancer survivors suggests that a chemotherapy drug could greatly raise patients' long-term odds for hearing loss. The drug in question, cisplatin, has been a mainstay of cancer.

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New DDW Highlights podcast: 1 July 2024

Drug Discovery World

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week has seen some exciting advances in neuroscience drug discovery, including Phase II clinical trials for two potentially game-changing treatments, a synapse-regenerating drug for Alzheimer’s and a gene therapy for Parkinson’s, as well as the launch of DDW’s latest In Focus repor

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Women Less Likely to Get a 'Secondary Condition' Fixed During a Heart Surgery

Drugs.com

MONDAY, July 1, 2024 -- You're getting heart surgery, but your surgeon notices a new anomaly that perhaps could be fixed at the same time.That's more likely to happen if you're a man than a woman, new studies find.The findings came as little.

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Senior level moves within drug discovery

Drug Discovery World

There have been a significant number of changes in c-level positions within the industry over the last two months. Dale Levitzke, Chief Executive Officer, and Curtis Nicholson, Director of Sales for Europe, Middle East, and Africa (EMEA), Sphere Fluidics: Levitzke brings over 25 years’ experience in the life science tools, biopharma, and biotechnology industries.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Diets Heavy in Ultra-processed Foods Linked to Earlier Death: Study

Drugs.com

MONDAY, July 1, 2024 -- People who eat more ultra-processed foods are more likely to suffer an early death, particularly from heart disease or diabetes, a new study warns.Older adults who consume higher amounts of ultra-processed foods are about.

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DDW Highlights: 1 July 2024

Drug Discovery World

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week has seen some exciting advances in neuroscience drug discovery, including Phase II clinical trials for two potentially game-changing treatments, a synapse-regenerating drug for Alzheimer’s and a gene therapy for Parkinson’s, as well as the launch of DDW’s latest In Focus repor

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Common Chemo Drug May Be Linked to Hearing Loss

Drugs.com

MONDAY, July 1, 2024 (HealthDay news) -- A 14-year study of testicular cancer survivors suggests that a chemotherapy drug could greatly raise patients' long-term odds for hearing loss. The drug in question, cisplatin, has been a mainstay of cancer.

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How can pharmaceutical marketing evolve with generic entry? The example of Lipitor

Drug Patent Watch

Lipitor’s marketing strategy underwent a significant evolution as generic competition emerged, employing aggressive tactics to retain market share and brand […] Source

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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More Green Spaces, Lakes Bring Fewer Hardened Arteries

Drugs.com

MONDAY, July 1, 2024 -- Parks and lakes aren’t just good for your soul -- new research suggests they also appear to protect your arteries.Living near green space and “blue” water space lowers a person’s odds of hardened arteries in middle-aged urban.

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Scientists turn white fat cells into calorie-burning beige fat

Science Daily: Pharmacology News

Researchers have figured out how to turn ordinary white fat cells, which store calories, into beige fat cells that burn calories to maintain body temperature.

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Not 'Out of Your League': Folks Tend to Marry People as Attractive as They Are

Drugs.com

MONDAY, July 1, 2024 -- People largely date and marry people in their own “league,” as far as beauty is concerned, a new review finds.Men and women are fairly accurate at rating their own physical attractiveness, and they tend to choose mates who ha.

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Eisai and Bristol Myers cancel cancer ADC deal

BioPharma Drive: Drug Pricing

The Japan-based drugmaker said its U.S. partner’s “portfolio prioritization efforts” led to the termination. It will refund part of an upfront payment.

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Prosthetic Legs Controlled by Person's Own Neural System Bring Natural Gait

Drugs.com

MONDAY, July 1, 2024 -- “Smart” prosthetic legs can help amputees achieve a natural walking gait, but it’s done through robotic sensors and algorithms that drive the limb forward at predetermined rates.A better way would be to give people full contr.

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Dampening the 'seeds' of hurricanes

Science Daily: Pharmacology News

Increased atmospheric moisture may alter critical weather patterns over Africa, making it more difficult for the predecessors of many Atlantic hurricanes to form, according to a new study.

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FDA Study Shows Pasteurization Kills Bird Flu in Milk

Drugs.com

MONDAY, July 1, 2024 -- As bird flu continues to spread among U.S. dairy cows, reassuring new government research finds the pasteurization process widely used in the industry effectively kills all bird flu virus in milk.In a health update posted.

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Sixty-million-year-old grape seeds reveal how the death of the dinosaurs may have paved the way for grapes to spread

Science Daily: Pharmacology News

Scientists discovered the oldest fossil grapes in the Western Hemisphere, which help show how after the death of the dinosaurs, grapes spread across the world.

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Eli Lilly inks another radiopharma deal, gaining option to buy startup

BioPharma Drive: Drug Pricing

Under an arrangement with Radionetics, Lilly will have rights to acquire the San Diego biotechnology company for $1 billion.

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Weight change across common antidepressant medications

Science Daily: Pharmacology News

A new study compared weight change across eight common first-line antidepressants for patients taking an antidepressant for the first time. The study found differences in weight change between the different antidepressants after medication initiation, with bupropion consistently showing the least weight gain. The study adds rigorous evidence on expected weight gain across common antidepressant treatments.

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10 clinical trials to watch in the second half of 2024

BioPharma Drive: Drug Pricing

Study results are expected for a pair of closely watched obesity drugs, while key tests await for a high-priced AbbVie acquisition and one of 2023’s largest IPOs.

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The evidence is mounting: humans were responsible for the extinction of large mammals

Science Daily: Pharmacology News

Human hunting, not climate change, played a decisive role in the extinction of large mammals over the last 50,000 years. This conclusion comes from researchers who reviewed over 300 scientific articles from many different fields of research.

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Tai Chi Can Benefit Breast Cancer Survivors in Many Ways

Drugs.com

MONDAY, July 1, 2024 -- Tai Chi appears to improve sleep, and as a result reduces inflammation and boosts the immune systems of breast cancer survivors, a new study says.The ancient Chinese martial arts practice relies on slow, precise movements.

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Largest ever genetic study of age of puberty in girls shows links with weight gain

Science Daily: Pharmacology News

Genes can indirectly influence the age at which girls have their first period by accelerating weight gain in childhood, a known risk factor for early puberty. Other genes can directly affect age of puberty, some with profound effects.

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With new IPO pitch, Artiva touts ‘natural killer’ cell therapy for autoimmune disease

BioPharma Drive: Drug Pricing

Like many of its cell therapy peers, Artiva, which originally sought an IPO in 2021, has shifted its strategy in hopes of riding a recent wave of investor interest in autoimmune disease research.

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Self-assembling, highly conductive sensors could improve wearable devices

Science Daily: Pharmacology News

To advance soft robotics, skin-integrated electronics and biomedical devices, researchers have developed a 3D-printed material that is soft and stretchable -- traits needed for matching the properties of tissues and organs -- and that self-assembles. Their approach employs a process that eliminates many drawbacks of previous fabrication methods, such as less conductivity or device failure, the team said.

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A Molecular Biologist’s Advice For Life

LifeSciVC

Having just turned 50, I’ve been reflecting on my first half-century of late… many fun and impactful moments, a few regrets, and a life I’ve tried to live to the fullest. One thread that has run throughout it has been my passion for science as a lens for looking at the world. In particular, I love connecting science to daily life. I’m reminded of the DuPont advertising slogan of “ Better Living Through Chemistry ” – which was representative of the role of science in improving everyday lives in t

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Layers of carbonate provide insight into the world of the ancient Romans

Science Daily: Pharmacology News

Archaeologists face a major challenge when they intend to acquire information about buildings or facilities of which only ruins remain. This was a particular challenge for the remnants of the Roman water mills in Barbegal in Southern France, dating back to the 2nd century CE. This unique industrial complex consisted of 16 water wheels placed in parallel rows.

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Celebrating 20 Years of the Nanotechnology Research Center: Highlights from Engineering Controls and Personal Protective Equipment

NIOSH Science Blog: Drugs

As the National Institute for Occupational Safety and Health (NIOSH) Nanotechnology Research Center (NTRC) marks its 20th anniversary, we celebrate the creative work of the Engineering Controls and Personal Protective Equipment (PPE) critical topic area, one of the ten critical nanotechnology topic areas of the NTRC. NIOSH researchers have established both research publications and guidance to help reduce worker exposures to engineered nanoparticles and biological aerosol particles.

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A prosthesis driven by the nervous system helps people with amputation walk naturally

Science Daily: Pharmacology News

With a new surgical intervention and neuroprosthetic interface, researchers restored a natural walking gait in people with amputations below the knee. Seven patients were able to walk faster, avoid obstacles, and climb stairs more naturally than people with a traditional amputation.