Drug Discovery World

NOVEMBER 8, 2023

Kinnov Therapeutics’ Phase II study for its lead compound KT-110 has shown that the treatment can halve alcohol consumption amongst heavy drinkers in three months. The trial showed that KT-110 has superior efficacy in significantly reducing alcohol consumption in heavy drinkers by 26 to 30 grams (2.6-3 drinks) per day compared to the placebo. This increased to 50 grams (five drinks) per day compared to the baseline measure at the start of treatment.

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Forbes: Drug Truths

NOVEMBER 8, 2023

Medicare will save money but there will be fewer new medicines.

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Drug Discovery World

NOVEMBER 8, 2023

Deepika Khedekar , Associate Centralized Clinical Lead at IQVIA, explains how artificial intelligence could make clinical trials more accurate, accessible and standardised. Over 19 million 1 hearts succumb to cardiovascular disease yearly, while around 10 million 2 lives are claimed by cancer every year. To put this scale into perspective, these numbers surpass the combined population of the Netherlands, Hong Kong, and Singapore.

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BioPharma Drive: Drug Pricing

NOVEMBER 8, 2023

A gene editing therapy developed by Vertex Pharmaceuticals and CRISPR Therapeutics can mute sickle cell disease’s most damaging symptoms. Yet treatment may not be as simple as its dramatic benefit makes it seem.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Drug Discovery World

NOVEMBER 8, 2023

The UK lags comparable countries, including France and Germany, on the degree of availability of treatments for rare diseases, according to a new report. The report by the BIA and consultancy firm PwC has highlighted the progress that has been made in improving access to rare disease treatments in the UK, and the challenges that remain. The report, ‘Evaluating patient access to rare disease treatments: Insights from the UK and beyond’, is based on a series of interviews and focus groups with key

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Disease Treatment International Pharmaceuticals 130

NIOSH Science Blog: Drugs

NOVEMBER 8, 2023

Despite legislation and improved technology, data from Massachusetts hospitals show that sharps injuries have increased in the operating room (OR) [1]. These injuries place healthcare workers at risk of exposure to bloodborne pathogens (BBPs). There is an urgent need to renew efforts to protect healthcare workers inside the operating room. The Massachusetts data highlight a gap and the need to establish a national surveillance program that would help hospitals develop further measures to prevent

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Hospitals 114

BioPharma Drive: Drug Pricing

NOVEMBER 8, 2023

The pharmaceutical company will sell the GLP-1 drug, branded as Zepbound, at a list price about 20% lower than Novo Nordisk's competing drug Wegovy.

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Pharmaceutical Companies FDA Drugs Pharmaceuticals 123

Drug Discovery World

NOVEMBER 8, 2023

The DDW Turning Science into Business Summit, ‘Cancer research opportunities and advances ’ is a free summit offering expert thought leadership on cancer research, precision medicine and immunotherapy. Sponsored by Taconic, the event will take place online on 16 November at 7AM PST / 10AM EST / 3PM GMT / 4PM CET and will be available on-demand. You will hear from Joseph R Peterson, PhD, CTO & Co-founder, SimBioSys, in his session on genomics and personalised medicine ‘Unlock novel cancer ins

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Research Science Drugs 130

Antidote

NOVEMBER 8, 2023

The medical research industry is fast-moving. Despite the fact that the average clinical trial lasts about 10 years , new discoveries are happening all the time. However, keeping up with new developments can be a challenge.

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Clinical Trials Trials Research 105

SCIENMAG: Medicine & Health

NOVEMBER 8, 2023

1 in 25 carries a genotype that is associated with a shortened lifespan Credit: deCODE Genetics 1 in 25 carries a genotype that is associated with a shortened lifespan Scientists at deCODE genetics, a subsidiary of Amgen, have published a study on actionable genotypes detected in the Icelandic population and their association with lifespan.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Science Daily: Pharmacology News

NOVEMBER 8, 2023

Physicists have trapped electrons in a pure crystal, marking the first achievement of an electronic flat band in a three-dimensional material. The results provide a new way for scientists to explore rare electronic states in 3D materials.

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BioPharma Drive: Drug Pricing

NOVEMBER 8, 2023

CEO Chris Viehbacher said the company has “the elements to think about a return to topline growth.” Yet, that goal hinges on the successful commercialization of multiple new products.

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Production 67

Science Daily: Pharmacology News

NOVEMBER 8, 2023

New research helps explain how sharp patterns form on zebras, leopards, tropical fish and other creatures. Their findings could inform the development of new high-tech materials and drugs.

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Chemical Biology and Drug Design

NOVEMBER 8, 2023

Cover Image © molekuul_be/Shutterstock.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

NOVEMBER 8, 2023

A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug's power against fungal infections while doing away with its toxicity, researchers report.

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The Open Targets Blog

NOVEMBER 8, 2023

This summer, Jason Menkiti joined the Open Targets team as part of an eight-week internship through Health Data Research UK and the 10,000 Black Interns programme , which aims to provide STEM students and graduates with an experience related to improving healthcare through data research. Jason recently graduated with a Masters in Computer Science from the University of Warwick.

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International Science Disease Research 64

Science Daily: Pharmacology News

NOVEMBER 8, 2023

Scientists just made a breakthrough discovery in revealing how planets are made. By observing water vapor in protoplanetary disks, they confirmed a physical process involving the drifting of ice-coated solids from the outer regions of the disk into the rocky-planet zone.

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Perficient: Drug Development

NOVEMBER 8, 2023

Perficient is pleased to announce that our work in health equity, diversity and inclusion has gained recognition in the 2023 eHealthcare Leadership Awards. Our work in the healthcare industry emphasizes the importance of a well-planned and executed strategy for addressing health equity, diversity, and inclusion. This work creates a healthier and more welcoming environment for team members to build patient trust, elevate consumer satisfaction and drive higher-quality care.

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Science 64

Science Daily: Pharmacology News

NOVEMBER 8, 2023

Huntington's disease causes involuntary movements and dementia, has no cure, and is fatal. Scientists have now shown they can slow its progression in flies and worms, opening the door to human treatments.

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Disease Treatment 72

BioPharma Drive: Drug Pricing

NOVEMBER 8, 2023

Company head Bill Anderson said Bayer may separate its consumer health or crop science business, and signaled “significant” layoffs are in the future.

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Science 67

Science Daily: Pharmacology News

NOVEMBER 8, 2023

When animals 'sing' sitting on the ground -- such as when crickets chirp -- their volume and reach increase dramatically, by as much as ten-fold. This result contradicts long-held beliefs in the field of animal communication, which presume the ground is a hindrance to sound transmission.

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BioPharma Drive: Drug Pricing

NOVEMBER 8, 2023

The agency claims intellectual property for emergency allergy shot EpiPen and asthma medication Advair was “improperly listed” in an FDA database.

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FDA 67

Science Daily: Pharmacology News

NOVEMBER 8, 2023

Neuroscientists have discovered a fascinating connection between the retention of early life memories and brain developmental trajectories associated with autism.

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Drug Patent Watch

NOVEMBER 8, 2023

Annual Drug Patent Expirations for XEPI Xepi is a drug marketed by Ferrer Internacional and is included in one NDA. It is available from one supplier. There are three patents… The post New patent expiration for Ferrer Internacional drug XEPI appeared first on DrugPatentWatch - Make Better Decisions.

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Cytel

NOVEMBER 8, 2023

Written by Natalia Muehlemann, Vice President, Clinical Development, and Ari Brettman, Senior Managing Director, Blackstone Life Sciences When working with investors, it’s critical that drug and device developers consider how their clinical trial design aligns with investment priorities. Natalia Muehlemann and Ari Brettman discuss what investors look for when evaluating clinical development programs, and the value of simulation-guided design in informing decisions and facilitating communication

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Clinical Trials Trials Clinical Development Science 59

Drug Patent Watch

NOVEMBER 8, 2023

Annual Drug Patent Expirations for OPFOLDA Opfolda is a drug marketed by Amicus Therap Us and is included in one NDA. It is available from one supplier. The generic ingredient… The post New patent for Amicus Therap drug OPFOLDA appeared first on DrugPatentWatch - Make Better Decisions.

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Science Daily: Pharmacology News

NOVEMBER 8, 2023

Under propofol general anesthesia, sensory input still reaches the brain, but signals do not spread. A new study suggests consciousness requires cortical regions to all be 'on the same page.

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Drug Patent Watch

NOVEMBER 8, 2023

Annual Drug Patent Expirations for UPNEEQ Upneeq is a drug marketed by Rvl Pharms and is included in one NDA. It is available from one supplier. There are eleven patents… The post New patent for Rvl Pharms drug UPNEEQ appeared first on DrugPatentWatch - Make Better Decisions.

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Fierce BioTech

NOVEMBER 8, 2023

Unlocking the Future: Navigating the Next Phase of Biologics through the CDMO Lens pesurya Wed, 11/08/2023 - 14:04 Wed, 12/13/2023 - 11:00 Resource Type Webinar Elena Dukhovlinova, Ph.D. Will Boomershine Michelle Mayer Promotion Start Wed, 11/15/2023 - 09:00 Promotion End Wed, 05/15/2024 - 09:00 Duration 60 Minutes Explore the pivotal role of Contract Development and Manufacturing Organizations (CDMOs) in the biopharmaceutical industry.

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Production 52

Drug Patent Watch

NOVEMBER 8, 2023

Annual Drug Patent Expirations for IGALMI Igalmi is a drug marketed by Bioxcel and is included in one NDA. It is available from one supplier. There are four patents protecting… The post New patent for Bioxcel drug IGALMI appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

Fierce BioTech

NOVEMBER 8, 2023

We are living in a period of what feels like an exponential rate of change when it comes to advances in technology and innovation. | Mary Claire Duch of Real Chemistry and Kathleen Tregoning from Cerevel Therapeutics talk all things AI in biotech, as well as the importance of countering misinformation through accurate and well-targeted communications.

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Drug Patent Watch

NOVEMBER 8, 2023

Annual Drug Patent Expirations for BOSULIF Bosulif is a drug marketed by Pf Prism Cv and is included in two NDAs. It is available from two suppliers. There are five… The post New patent for Pf Prism drug BOSULIF appeared first on DrugPatentWatch - Make Better Decisions.

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Perficient: Drug Development

NOVEMBER 8, 2023

Introduction to Vue.js: Vue.js is a user-friendly and progressive JavaScript framework that simplifies building dynamic web applications. It’s known for its flexibility and ease of integration, making it a popular choice for developers. Here’s a straightforward guide to creating a Vue.js application: Prerequisites: Node.js version 10.6.0 or greater installed on your computer.

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Drug Discovery World

NOVEMBER 8, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. On Day 1, Tuesday 14 November 2023, the tracks include: Display of biologics, antibody-based cancer therapies, safety and efficacy of bispecific antibodies, modulating the tumour microenvironment, optimisation and developability, and cell line and systems engineering.

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