A greener, more effective way to kill termites
Science Daily: Pharmacology News
MAY 31, 2024
Scientists have discovered a highly effective, nontoxic, and less expensive way to lure hungry termites to their doom.
Fri.May 31, 2024
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Almost 1 in 3 Americans Know Someone Who's Died From a Drug Overdose
Drugs.com
MAY 31, 2024
FRIDAY, May 31, 2024 -- As the opioid addiction crisis continues to lay waste to American life, a new survey finds that nearly a third of U.S. adults now know someone who's died of a drug overdose. Conducted in the spring of 2023, the survey of.
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Martian meteorites deliver a trove of information on Red Planet's structure
Science Daily: Pharmacology News
MAY 31, 2024
Mars has a distinct structure in its mantle and crust with discernible reservoirs, and this is known thanks to meteorites that scientists have analyzed. These results are important for understanding not only how Mars formed and evolved, but also for providing precise data that can inform recent NASA missions like Insight and Perseverance and the Mars Sample Return.
Caffeine Affects Dopamine Function in Parkinson's Patients
Drugs.com
MAY 31, 2024
FRIDAY, May 31, 2024 -- Caffeine has been associated with a reduced risk of developing Parkinson’s disease, but a new study says a coffee jolt might not be good for people already diagnosed with the brain disorder. Consuming caffeine appears.
Bridging Innovation & Patient Care: The Growing Role of AI
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
FDA staff outline shortcomings of Lykos data for MDMA therapy
BioPharma Drive: Drug Pricing
MAY 31, 2024
Ahead of an advisory panel meeting, agency staff identified several sticking points in the clinical results backing Lykos’ ecstasy-based treatment for PTSD.
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Discovery of a DCAF11-dependent cyanoacrylamide-containing covalent degrader of BET-proteins
Covalent Modifiers
MAY 31, 2024
Gary Tin, Marko Cigler, Matthias Hinterndorfer, Kevin D. Dong, Hana Imrichova, Steven P. Gygi, Georg E. Winter, Bioorganic & Medicinal Chemistry Letters , 2024 [link] Targeted protein degradation is mediated by small molecules that induce or stabilize protein–protein interactions between targets and the ubiquitin–proteasome machinery. Currently, there remains a need to expand the repertoire of viable E3 ligases available for hijacking.
Mediterranean Diet Cuts Women's Risk of Early Death by 23%
Drugs.com
MAY 31, 2024
FRIDAY, May 31, 2024 -- Experts have long extolled the benefits of the Mediterranean diet and a new study adds to that evidence, finding it cuts the odds for an early death in women by 23%. “For women who want to live longer, our study says.
FDA delays decision on Dupixent in COPD; Summit makes a bold claim
BioPharma Drive: Drug Pricing
MAY 31, 2024
Regeneron and Sanofi now expect an FDA verdict in September. Elsewhere, Summit claimed victory over Keytruda and Neurocrine’s longtime CEO revealed plans to step down.
Could Tough Workouts Trigger a Hot Flash?
Drugs.com
MAY 31, 2024
FRIDAY, May 31, 2024 -- While going through menopause, many women who gain weight head to the gym for intense workouts, but new research suggests that too much exercise may help trigger another side effect: hot flashes. In a report published May 29.
From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Inclusive Pattern Generation Protocols to Decode Thiol-Mediated Uptake
Covalent Modifiers
MAY 31, 2024
Saidbakhrom Saidjalolov, Filipe Coelho, Vincent Mercier, Dimitri Moreau, and Stefan Matile ACS Central Science 2024 10 (5), 1033-1043 DOI: 10.1021/acscentsci.3c01601 Thiol-mediated uptake (TMU) is an intriguing enigma in current chemistry and biology. While the appearance of cell-penetrating activity upon attachment of cascade exchangers (CAXs) has been observed by many and is increasingly being used in practice, the molecular basis of TMU is essentially unknown.
Suicidal Impulses May Peak During Restless Nights
Drugs.com
MAY 31, 2024
FRIDAY, May 31, 2024 -- The wee hours of the morning could be the most dangerous for someone on the brink of suicide or homicide, a new study shows. There’s a five-fold greater risk for suicide and an eight-fold greater risk for homicide.
Novartis study points to larger role for targeted leukemia drug
BioPharma Drive: Drug Pricing
MAY 31, 2024
Results from a trial called ASC4FIRST show Scemblix outperformed Gleevec and other kinase inhibitors in treating newly diagnosed chronic myeloid leukemia.
U.S. Deaths Linked to ATVs Rose by a Third in One Year
Drugs.com
MAY 31, 2024
FRIDAY, May 31, 2024 -- In just one year, U.S. deaths linked to the use of all-terrain vehicles (ATVs) jumped by a third, according to the latest report from the Consumer Product Safety Commission. With another summer set to begin and ATVs brought.
How Machine Learning Drives Clinical Trial Efficiency
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
On National Cancer Survivors Day, celebrating the power of research
Antidote
MAY 31, 2024
This Sunday, June 2, is National Cancer Survivors Day , designed to be a celebration for those who have survived cancer and an inspiration for those recently diagnosed. Since 1991, the national cancer death rate has dropped by 33% , partially due to advancements in treatment, early detection, and reduced smoking rates.
Stress, Discrimination Add to Cancer Burden for LGBTQ+ Americans
Drugs.com
MAY 31, 2024
FRIDAY, May 31, 2024 -- While LGBTQ+ people have higher risk factors for cancer, they are apt to face discrimination when in need of high-quality medical care, a new report shows. In particular, LGBTQ+ people have to worry that a health care.
New tentative approval for MSN drug dabigatran etexilate mesylate
Drug Patent Watch
MAY 31, 2024
Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five… Source
1 in 8 Older Americans Are Stricken With Traumatic Head Injury
Drugs.com
MAY 31, 2024
FRIDAY, May 31, 2024 -- About one in eight U.S. seniors will be treated for a traumatic brain injury, typically during a fall, a new study finds. Medicare data shows that about 13% of seniors suffered a severe concussion during an average follow-up.
Deliver Fast, Flexible Clinical Trial Insights with Spotfire
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
New tentative approval for Annora Pharma drug brivaracetam
Drug Patent Watch
MAY 31, 2024
Brivaracetam is the generic ingredient in two branded drugs marketed by Ucb Inc, Aurobindo Pharma Ltd, Lupin Ltd, Sunshine, and Zydus Pharms and, and is included in seven NDAs.
Night Owls Could Be Upping Their Mental Health Risks
Drugs.com
MAY 31, 2024
FRIDAY, May 31, 2024 -- People who regularly stay up until the wee hours of the morning could be harming their mental health, a new study finds. Regardless of whether people were morning larks or a night owls, they tended to have higher rates of.
Which pharmaceutical drugs have the most drug patents in Czech Republic?
Drug Patent Watch
MAY 31, 2024
This chart shows the drugs with the most patents in Czech Republic.
Unpacking FDA’s long-awaited platform technology designation program and guidance
Agency IQ
MAY 31, 2024
BY RACHEL COE, MSC Months overdue, the FDA’s Platform Technologies Designation guidance document has just been published by the agency. AgencyIQ breaks down what the designation means for sponsors and its limits for product sponsors. As part of the 2023 Consolidated Appropriations Act (Section 2503), Congress directed FDA to establish a new “Platform Technologies Designation” program.
Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
New patent for Maia Pharms drug ANGIOMAX RTU
Drug Patent Watch
MAY 31, 2024
Annual Drug Patent Expirations for ANGIOMAX+RTU Angiomax Rtu is a drug marketed by Maia Pharms Inc and is included in one NDA. It is available from three suppliers.
What we expect the EPA to do in June 2024
Agency IQ
MAY 31, 2024
BY WALKER LIVINGSTON, ESQ In this returning feature, AgencyIQ looks at public data to determine what the EPA is planning to do in the month ahead, including deadlines, meetings, events, planned regulations, comment periods, and more. The EPA has delayed the release of several TSCA risk management rules for existing chemicals – these may be released in June.
New patent for Sun Pharm drug WINLEVI
Drug Patent Watch
MAY 31, 2024
Annual Drug Patent Expirations for WINLEVI Winlevi is a drug marketed by Sun Pharm and is included in one NDA. It is available from one supplier.
AdComm votes in favor of new colorectal cancer screening test, but questions about serial testing and labeling remain
Agency IQ
MAY 31, 2024
BY LAURA DIANGELO, MPH In May 2024, the FDA’s Molecular and Clinical Genetics Device panel voted 7-2 in favor of the approval of a new blood-based screening test for colorectal cancer, which would be the first blood-based test of this type. Discussions at the panel meeting highlighted questions about the role of screening tests and their place in the clinical workflow, labeling for screening indications, and the challenges of studying “repeat” tests.
Custom Metadata Types and Custom Settings in Salesforce
Perficient: Drug Development
MAY 31, 2024
In Salesforce, data storage and configuration management are crucial for maintaining robust and scalable applications. Two powerful tools that Salesforce developers and administrators frequently use to handle this are Custom Metadata Types and Custom Settings. While both serve unique purposes, they offer distinct benefits and come with their own best practices.
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