Mon.Apr 22, 2024

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Few Young Adults Could Administer Naloxone to Reverse Fentanyl Overdose

Drugs.com

MONDAY, April 22, 2024 -- Even though fentanyl-linked fatal overdoses are soaring among young adults, a new survey of American college students found that just 1 in 7 knew how to administer the overdose antidote drug naloxone.Many who took the.

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3 in 5 parents play short order cook for young children who don't like family meal

Science Daily: Pharmacology News

While most parents of preschool and elementary aged children strive to give their children a balanced, nutritional diet, some of their strategies to promote healthy eating may backfire, a national poll suggests.

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Lilly to buy injectable drug plant in manufacturing ramp-up

BioPharma Drive: Drug Pricing

The acquisition of a Nexus Pharmaceuticals facility in Wisconsin could help Lilly better meet demand for injectable medicines, like those it makes for diabetes and obesity.

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AI and physics combine to reveal the 3D structure of a flare erupting around a black hole

Science Daily: Pharmacology News

Based on radio telescope data and models of black hole physics, a team has used neural networks to reconstruct a 3D image that shows how explosive flare-ups in the disk of gas around our supermassive black hole might look.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Bristol Myers taps startup to boost CAR-T production

BioPharma Drive: Drug Pricing

A partnership with Cellares, worth up to $380 million, is meant to help Bristol Myers speed and scale manufacture of the complex cellular treatments.

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EPA Designates Two 'Forever Chemicals' as Hazardous

Drugs.com

MONDAY, April 22, 2024 -- Two common PFAS "forever chemicals" have been deemed hazardous substances by the Environmental Protection Agency.The new designation, enacted under the country's Superfund law, will let the EPA investigate and clean up.

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Eisai hunts for next Alzheimer’s drug with new research pact

BioPharma Drive: Drug Pricing

A collaboration with BioArctic will focus on a technology designed to more effectively deliver drugs in the brain, following similar efforts by Roche.

Research 118
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Giant galactic explosion exposes galaxy pollution in action

Science Daily: Pharmacology News

Astronomers have produced the first high-resolution map of a massive explosion in a nearby galaxy, providing important clues on how the space between galaxies is polluted with chemical elements.

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What Folks Consider 'Old Age' Is Getting Older

Drugs.com

MONDAY, April 22, 2024 -- People’s idea of “old age” is aging itself, with middle-aged folks and seniors believing that old age starts later in life than did peers from decades ago, a new study finds.The study revolves around the question.

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This alloy is kinky

Science Daily: Pharmacology News

Researchers have uncovered a remarkable metal alloy that won t crack at extreme temperatures due to kinking, or bending, of crystals in the alloy at the atomic level. Unlike most materials, the new alloy keeps its shape and resists cracking at both high and low temperature extremes, making it potentially suitable for demanding applications like high-efficiency aerospace engines.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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A-Fib More Common in Middle-Aged Folk Than Thought

Drugs.com

MONDAY, April 22, 2024 -- The dangerous heart rhythm disorder called atrial fibrillation is becoming more common in middle-aged people, a new study warns.More than a quarter of patients at the University of Pittsburgh Medical Center (UPMC) seeking.

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Perficient Wins the Köerber OMS New Partner of the Year 2023 North America!

Perficient: Drug Development

We’re excited to share some wonderful news with you all! Perficient achieved the Köerber 2023 Evolve Partner Award for New OMS Partner of the Year North America. We see this as a shared achievement, one that wouldn’t be possible without the support of our incredible team and partner Köerber. Recognizing Excellence in the Supply Chain The Evolve Partner Awards have been established to recognize the efforts of Köerber’s partners in key Sales and Customer Success categories, which are related

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U.S. Measles Cases Reach 125, Surpassing Recent Peak in 2022

Drugs.com

MONDAY, April 22, 2024 -- Measles infections continue to spread across the country, with 125 cases now reported in 18 states, new U.S. government data shows.That is more cases than were reported in all of 2022, the most recent annual peak.

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Superradiant atoms could push the boundaries of how precisely time can be measured

Science Daily: Pharmacology News

Superradiant atoms can help us measure time more precisely than ever. In a new study, researchers present a new method for measuring the time interval, the second, mitigating some of the limitations that today's most advanced atomic clocks encounter. The result could have broad implications in areas such as space travel, volcanic eruptions and GPS systems.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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WHO Chief Sounds Alarm on Bird Flu Circulating in U.S. Cattle

Drugs.com

MONDAY, April 22, 2024 -- The H5N1 avian flu virus that's infecting U.S. cattle is increasingly showing up in mammals -- a dangerous sign that it could someday easily infect people.That's the warning issued late last week by World Health.

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Developing the next generation of antibody drug conjugates

Drug Target Review

What are the primary methods used for bioconjugation in antibody drug-conjugate (ADC) development, and how do they influence the stability and efficacy of the resulting ADCs? Site-specific conjugation methods are primarily utilised for a significant portion of ADCs in clinical developments. Despite excellent pharmacokinetic and stable antibody-linker connections, such ADCs have yet to receive market approval.

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Pandemic Had Only Minor Effect on Young Kids' Development

Drugs.com

MONDAY, April 22, 2024 -- The pandemic caused only “modest” delays in developmental milestones for infants and toddlers, a new study has found.

Research 105
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Support for Existing Expertise: Community-focused training initiatives to improve the safety and health of Tribal buffalo herd workers

NIOSH Science Blog: Drugs

American bison, also known as buffalo, are the largest land mammal in North America and are perfectly adapted to the harsh landscape of the high plains, capable of surviving extreme winters, vast changes in temperature, drought conditions, high humidity, and many diseases that impact other hoofed mammals. In recent decades, indigenous communities across North America and organizations such as the Intertribal Buffalo Council (ITBC) have led efforts to bring the buffalo home to Tribal lands.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Relationship With Partner Affects Outcomes for Breast Cancer Survivors

Drugs.com

MONDAY, April 22, 2024 -- A strong relationship can help a breast cancer survivor thrive in the aftermath of their terrible ordeal, a new study finds.

Treatment 105
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Pharmas form joint venture to jumpstart Japanese drug research

BioPharma Drive: Drug Pricing

A new initiative backed by Takeda, Astellas and Sumitomo Mitsui Banking aims to combat a decade-long decline in drug R&D productivity in Japan.

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Drug Patent Expirations for the Week of April 21, 2024

Drug Patent Watch

SOOLANTRA (ivermectin) Galderma labs lp Patent: 7,550,440 Expiration: Apr 22, 2024 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.

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How can pharma speed time to treatment? Digital tools can help

BioPharma Drive: Drug Pricing

Treatment delays can seriously impact patients’ health outcomes. But by leveraging digital tools, pharma can help them find and access specialist care early in their journey.

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Many Parents Cook Special Meals for Little Picky Eaters: Poll

Drugs.com

MONDAY, April 22, 2024 -- Parents too often wave the white flag when it comes to young picky eaters, a new survey finds.Three out of five parents say they’re willing to play personal chef and cobble up a separate meal for a child who balks at the.

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Defining Probability of Success in Clinical Trial Design with Commercial Software and R Coding

Cytel

Written by Boaz N. Adler, Director, Global Product Engagement, and J. Kyle Wathen, Vice President, Scientific Strategy & Innovation One of the pivotal metrics considered when designing a clinical trial is the study’s probability of success, which can be measured in several ways. Each definition of probability of success has benefits and limitations both in the way it is measured, and the way it is accounted for in study design and execution.

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Ipsen, Skyhawk to develop RNA-targeting pills for rare brain diseases

BioPharma Drive: Drug Pricing

The deal, which could be worth up to $1.8 billion, is the latest research collaboration involving small molecule drugs that modify RNA.

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New patent for Esperion Theraps drug NEXLETOL

Drug Patent Watch

Annual Drug Patent Expirations for NEXLETOL Nexletol is a drug marketed by Esperion Theraps Inc and is included in one NDA. It is available from one supplier.

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Meet the Expert: Sarah Giorgio

thought leadership

Our "Meet the Expert" series introduces you to our team of experts around the world. This "behind the curtain" view will help you get to know who we are on a professional and personal level, and highlight how our colleagues work together on our higher purpose to improve patient health and safety throughout the complete product lifecycle.

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New patent expiration for Currax drug ONZETRA XSAIL

Drug Patent Watch

Annual Drug Patent Expirations for ONZETRA+XSAIL Onzetra Xsail is a drug marketed by Currax and is included in one NDA. It is available from one supplier.

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Understanding Perceptible Information for Multi-Modal Communication in Universal Design – 1

Perficient: Drug Development

In the realm of universal design, ensuring that information is perceptible through various modes of communication is paramount to creating inclusive environments. This involves accommodating the diverse needs and preferences of individuals, regardless of their abilities or backgrounds. Let’s explore why understanding perceptible information for multi-modal communication is essential in universal design.

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New patent expiration for Horizon drug RAYOS

Drug Patent Watch

Annual Drug Patent Expirations for RAYOS Rayos is a drug marketed by Horizon and is included in one NDA. It is available from one supplier.

Drugs 59
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Understanding Perceptible Information for Clear and Consistent Feedback in Universal Design – 2

Perficient: Drug Development

In the pursuit of universal design, providing clear and consistent feedback is essential for ensuring that individuals can interact with products, environments, and services effectively, regardless of their abilities. Let’s delve into why understanding perceptible information for clear and consistent feedback is crucial in universal design. Feedback Loop Clear and consistent feedback creates a feedback loop between users and their environment or interaction, enabling individuals to underst

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Recorded Presentations: CDD 20th Anniversary User Group Meeting

Collaborative Drug

Recorded Presentations from CDD Experts

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Understanding Perceptible Information for Accessible Pedestrian Crossings in Universal Design – 3

Perficient: Drug Development

In the realm of universal design, ensuring accessible pedestrian crossings is essential for promoting safety, independence, and inclusivity for individuals of all abilities. Let’s explore why understanding perceptible information is crucial for creating accessible pedestrian crossings and how it contributes to universal design principles. Safety and Accessibility Accessible pedestrian crossings ensure the safety and accessibility of pedestrians, including individuals with disabilities, old