Drug Discovery World

MARCH 15, 2024

Valneva Scotland scooped two prizes at Scotland’s Life Sciences Awards 2024, including the award for Innovation – Pharma Services And Drug Discovery, in a ceremony on 14 March in Glasgow. Valneva Scotland is focused on vaccines for infectious diseases with significant unmet medical needs. The company’s vaccine for Chikungunya virus (IXCHIQ) was approved by the US Food and Drug Administration (FDA) in November 2023 and is the world’s first and only vaccine for Chikungunya.

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BioPharma Drive: Drug Pricing

MARCH 15, 2024

The company expects initial uptake of Rezdiffra, which costs $47,400 per year, to be slow as doctors and insurers establish the protocols needed to find patients eligible for treatment.

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Drug Discovery World

MARCH 15, 2024

News round-up for 11-15 March by DDW Digital Content Editor Diana Spencer. Following the recent AD/PD 2024 conference, which took place on 5-9 March in Lisbon, Portugal, there have been a number of key announcements regarding investigational therapies for neurological disorders, particularly Alzheimer’s disease and Parkinson’s disease. The top stories: New drug shows promising neuroprotective effects Galimedix Therapeutics has announced data showing small molecule GAL-201 has neuroprotective and

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Drug Target Review

MARCH 15, 2024

The discovery and development phases of biotherapeutic drugs leverage multiple technologies and processes across upstream and downstream stages of the bioprocess workflow. Advancements in cell line development (CLD), including screening and selection of final clones, scale up, automation and digitalisation have enabled precision and enhanced productivity.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

MARCH 15, 2024

Biotechnology company Allyx Therapeutics has reported positive Phase Ib clinical data for its lead compound, ALX-001, a first-in-class, synapse-targeted, disease-modifying oral therapy in development for neurodegenerative diseases. The findings were presented at the AD/PD 2024 Conference in Lisbon. The Phase Ib study examined the safety, tolerability and pharmacokinetics of twice-daily oral doses of ALX-001 in 32 heathy adult participants aged 50-80.

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Science Daily: Pharmacology News

MARCH 15, 2024

A new study challenges the current model of the universe by showing that, in fact, it has no room for dark matter.

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Research 130

Drugs.com

MARCH 15, 2024

FRIDAY, March 15, 2024 -- A parasite that can kill dogs has been found in a portion of the Colorado River that runs through Southern California.Heterobilharzia americana is a flatworm usually referred as liver fluke. It has never been reported.

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Drug Discovery World

MARCH 15, 2024

Exploristics and Exonate have announced the completion of a successful collaboration to optimise the study design for Exonate’s upcoming Phase IIb study for diabetic eye disease. The collaboration has supported ongoing development of Exonate’s lead candidate, EXN407, following a recent successful Phase Ib/IIa study in November. Using Exploristics’ study simulation software platform, KerusCloud, the companies established a more efficient, data-driven approach to study design and protocol developm

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Drugs.com

MARCH 15, 2024

FRIDAY, March 15, 2024 -- A salmon-and-mushroom sushi roll proved deadly for two restaurant patrons in Montana last year, and experts are sounding the alarm on the dangers of undercooked morel mushrooms. A total of 51 patrons at an unnamed.

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Drug Channels

MARCH 15, 2024

Today’s guest post comes from Josh Marsh, Vice President and General Manager of Sonexus™ Access and Patient Support at Cardinal Health. Josh discusses factors that drive manufacturers to insource versus outsource patient support services. He shares data from a Cardinal Health survey of biopharmaceutical companies and offers four factors to consider when evaluating your patient support program.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

MARCH 15, 2024

FRIDAY, March 15, 2024 -- Playing fetch or grooming Fido isn't just good for your precious pooch — it also benefits your brain.Such interactions appear to strengthen brain waves associated with rest and relaxation, South Korean researchers report.

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Collaborative Drug

MARCH 15, 2024

“Long Covid ‘Brain Fog’ May Be Due to Leaky Blood-Brain Barrier Ozempic Taking off in China? Is Exercise More Effective For Women than Men?

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Drugs.com

MARCH 15, 2024

FRIDAY, March 15, 2024 -- Attention, America: ignore the "experts" on TikTok and put your shoes on.Barefootin' is risky business, according to Dr. Sari Priesand, a foot specialist at Michigan Medicine-University of Michigan in Ann Arbor."Keep the.

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SCIENMAG: Medicine & Health

MARCH 15, 2024

The liver is not only the largest internal organ but also vital for human life as a metabolic center. It also possesses remarkable self-healing powers: even when large portions are removed, such as during surgery, they quickly regenerate in healthy individuals.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

MARCH 15, 2024

FRIDAY, March 15, 2024 -- Astronauts who have never had headaches may develop migraines and other tension-type headaches for the first time when they go into space.A side effect of zero gravity, these headaches start with motion sickness as.

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BioPharma Drive: Drug Pricing

MARCH 15, 2024

A majority of experts believed that the factors that may have led to an increased risk of early death in testing of Carvykti and Abecma aren’t as likely to occur outside of a clinical trial.

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Drugs.com

MARCH 15, 2024

FRIDAY, March 15, 2024 -- Millions of Americans whose livers develop scar tissue due to a common disease now have the first approved drug, Rezdiffra, to treat the condition, the U.S. Food and Drug Administration announced Thursday.The condition is.

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Collaborative Drug

MARCH 15, 2024

CDD User Group Meeting in Berlin. Contributions from experts at Bayer Co.Lab, PROTEROS biostructures GmbH, Refoxy Pharma, PROSION Therapeutics, Schrödinger.

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Drugs.com

MARCH 15, 2024

FRIDAY, March 15, 2024 -- Scientists have long noticed that folks who eat healthy have healthier brains as they age, including lowered odds for dementia.Now, researchers believe they know why: Regimens like the heart-healthy Mediterranean or DASH.

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Research 96

SCIENMAG: Medicine & Health

MARCH 15, 2024

Science China Life Sciences recently reported on the research results of Lanjuan Li’s team from Zhejiang university. Recent advances in microbiome research have revealed complex changes in gut microecology across various disease states, highlighting their profound impact on disease progression.

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Disease Science Research 78

Drugs.com

MARCH 15, 2024

FRIDAY, March 15, 2024 -- Doctors looking to help their patients head off dementia may want to ask for their address.An international team of researchers has linked accelerated brain aging and a higher risk of thinking declines to living in a.

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SCIENMAG: Medicine & Health

MARCH 15, 2024

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more. GPCRs translate stimuli that hit a cell from outside into an intracellular biochemical signal. Credit: Photo: Dr.

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Drugs.com

MARCH 15, 2024

FRIDAY, March 15, 2024 -- Millions of Americans whose livers develop scar tissue due to a common disease now have the first approved drug, Rezdiffra, to treat the condition, the U.S. Food and Drug Administration announced Thursday. The condition is.

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BioPharma Drive: Drug Pricing

MARCH 15, 2024

Sold as Breyanzi, the therapy is now cleared for use in certain adults with hard-to-treat forms of relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.

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Therapies 73

DrugBank

MARCH 15, 2024

The weight loss industry has emerged as a major hub for innovative research, groundbreaking treatments, and economic opportunity. According to Grand View Research , the global weight loss and weight management market size was valued at $142.5 billion in 2022 and is projected to grow at a compound annual growth rate of 9.94% from 2023 to 2030. Many drug discovery and repurposing initiatives are shifting focus to capturing a share of this market in light of Eli Lilly and the Novo Nordisk success.

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Drug Patent Watch

MARCH 15, 2024

For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.

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Pharmaceuticals Drugs 69

Agency IQ

MARCH 15, 2024

BY AMANDA CONTI Given the progressive nature of Alzheimer’s disease (AD), developing treatments for early-stage populations is crucial. FDA has now issued a second revision to its draft guidance on developing drugs for this population. The guidance walks through appropriate outcomes—including surrogate endpoints—but emphasizes the importance of getting agency input.

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Drug Patent Watch

MARCH 15, 2024

Rifaximin is the generic ingredient in one branded drug marketed by Salix Pharms and is included in one NDA. There are twenty-nine patents protecting this compound.

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Agency IQ

MARCH 15, 2024

BY WALKER LIVINGSTON, ESQ CalRecycle has launched the formal rulemaking process for Senate Bill 54, which will implement a sweeping plan to reduce plastic waste in the state by 2032. The newly released draft regulations, statement of reason and regulatory impact assessment all point to the wide-reaching implications that the rule will have for a variety of industries across the state.

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Drugs.com

MARCH 15, 2024

FRIDAY, March 15, 2024 -- Specialized brain scans may accurately predict whether a psychotic patient will go on to develop treatment-resistant schizophrenia, Dutch researchers report.The scan — called a neuromelanin-sensitive MRI, or NM-MRI for.

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Agency IQ

MARCH 15, 2024

BY LAURA DIANGELO, MPH In late 2023, the FDA finalized a long-awaited guidance on medical device cybersecurity – but also promised updates to that final guidance which would address certain statutory requirements. Today, the agency published a draft version of those “select updates,” which delineate how the FDA will interpret key statutory definitions and provide expectations for documentation and for bringing existing devices into compliance.

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Perficient: Drug Development

MARCH 15, 2024

Perficient, a leader in digital transformation, has been included as a company interviewed in Forrester’s recent report, “ Rethink Enterprise Applications Governance : Refocus Applications Governance And High-Performance IT Exploiting New Technologies To Win, Serve, And Retain Customers.” This comprehensive report explores the evolving landscape of enterprise applications governance, shedding light on the transformative potential of new technologies such as AI and cloud computi

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Government Compliance International Marketing 59

Agency IQ

MARCH 15, 2024

BY COREY JASEPH, MS, RAC The latest webinar from the CORE-MD consortium presented the group’s research into how patient-reported outcome measures have been used in clinical evaluations of high-risk medical devices. Researchers reported their findings from systematic literature reviews and a Delphi study of the use of different patient-reported outcome measures – and how patients thought these tools could be made better.

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Drug Target Review

MARCH 15, 2024

Could you explain how you got into STEM? As a child, I loved creative play, drawing, painting, crafting, and logic problems. Later on at school, Chemistry, Biology, and Art were my favourite subjects. Especially in chemistry, I loved the idea of studying something to understand it and then using that knowledge to make new molecules. Can you describe your personal journey that got you to where you are now?

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