Drug Discovery World

FEBRUARY 28, 2024

Lu Rahman selects some of the year’s interesting and noteworthy advances in cancer research drug discovery and development. As always, a year within cancer drug discovery and development brings with it significant breakthroughs, and 2023 has been no exception. Figures from the Amercian Cancer Society 1 state that “a little over 1.9 million new cancer cases are expected to be diagnosed in the US in 2023”.

Drug Development 163

Drug Development Research Clinical Trials Drugs 163

Nvidia Developer: Drug Discovery

FEBRUARY 28, 2024

Predicting 3D protein structures from amino acid sequences has been an important long-standing question in bioinformatics. In recent years, deep. Predicting 3D protein structures from amino acid sequences has been an important long-standing question in bioinformatics. In recent years, deep learning–based computational methods have been emerging and have shown promising results.

Bioinformatics 138

Bioinformatics Drugs 138

Drug Discovery World

FEBRUARY 28, 2024

The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended the approval of a Type II variation for Carvykti (ciltacabtagene autoleucel; cilta-cel) for the earlier treatment of relapsed and refractory multiple myeloma (RRMM). The recommended indication for cilta-cel is for the treatment of adult patients with RRMM, who have received at least one prior therapy, including an immunomodulatory agent (IMiD) and a proteasome inhibitor (PI), have dem

Therapies 130

Therapies Treatment FDA Production 130

Drugs.com

FEBRUARY 28, 2024

WEDNESDAY, Feb. 28, 2024 -- PFAS "forever" chemicals, increasingly linked to health risks, will no longer be added to food packaging handled by American consumers, the U.S. Food and Drug Administration announced Wednesday."Grease-proofing materials.

Packaging 111

Packaging FDA Drugs 111

Advertisement

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

FEBRUARY 28, 2024

The first 20 participants have been enrolled in a multicentre trial to test whether ImmunityBio’s Nant Cancer Vaccine (NCV) could potentially prevent colon and other cancers in individuals with Lynch syndrome. The vaccine comprises a tri-valent Adenovirus (Tri-Ad5) in combination with the company’s IL-15 superagonist N-803. With enrolment of the first two open-label phases of the trial completed, the study will now proceed to a randomised controlled Phase II study, which will include up to 186 i

Vaccine 130

Vaccine Trials Drugs Disease 130

Drugs.com

FEBRUARY 28, 2024

WEDNESDAY, Feb. 28, 2024 -- Once thought to be a bygone disease, measles is making a comeback in the United States and globally as folks shun a safe, surefire way to prevent it: The measles vaccine. But what is measles, and how easily does it.

Vaccine 111

Vaccine Disease 111

Drugs.com

FEBRUARY 28, 2024

WEDNESDAY, Feb. 28, 2024 -- What if you'd been treated for years for a condition, only to find out that you'd long ago been misdiagnosed?That's what's happening to a sizable number of Americans who are taking allergy meds (to little effect) when in.

110

110

Drug Discovery World

FEBRUARY 28, 2024

A new whitepaper is now available from DDW and Sartorius entitled ‘ iPSC-Derived Motor Neurons and Microglia From ALS Background Display Disease Phenotype ’. Induced pluripotent stem cell (iPSC)-derived cells are a significant resource for disease modelling. They allow the use of cells directly from affected patients and have the potential to guide these cells towards multiple lineages.

Disease 130

Disease Drugs 130

On Medicine

FEBRUARY 28, 2024

What is Perthes’ disease? Perthes’ Disease is a rare condition that affects the developing femoral head (the “ball” of the “ball and socket” hip joint) of a child due to poor blood supply. In this condition, the blood supply to the femoral head is disrupted and this leads to joint deformity. The destruction typically causes the femoral head to flatten and not fit well in the acetabulum (the “socket” of the hip joint).

Disease 109

Disease Doctors Treatment Trials 109

Drug Discovery World

FEBRUARY 28, 2024

A new study has highlighted the role of specific neuronal circuits in the brain involved in the development of anxiety, and distinct mechanisms of action of the therapeutic delta opioid receptor (DOP) agonist KNT-127. Understanding the neural circuits and molecular mechanisms that trigger anxiety can aid in the development of effective targeted pharmacological treatments.

Regulations 130

Regulations Therapies Science Treatment 130

Advertisement

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Perficient: Drug Development

FEBRUARY 28, 2024

Adobe Summit 2024 is right around the corner, and we’re excited to sit down with the executive director of marketing applications at Morgan Stanley Dorothy Joseph on March 27 at 11:30 A.M PST at The Grand Lux Café in The Palazzo. Perficient’s Jay Jackson, director of Adobe Digital Marketing and CDP, will host a fireside chat with Joseph about the global financial services leader’s successful journey to consolidate and optimize the Adobe Experience Platform.

Marketing 109

Marketing 109

Drugs.com

FEBRUARY 28, 2024

WEDNESDAY, Feb. 28, 2024 -- Live musical performances speak to the soul, stimulating the brain in ways more powerful than listening to a recorded tune does, new research finds.“Our study showed that pleasant and unpleasant emotions performed as.

Research 105

Research 105

Fierce BioTech

FEBRUARY 28, 2024

mRNA innovation is one of the most exciting and impactful areas of healthcare globally today. | Sitting down with Guido Seidel, Managing Director of Wacker Biotech, we explore some of the key challenges, opportunities and innovations for pharmaceutical companies to consider in mRNA manufacturing.

Pharmaceutical Companies 102

Pharmaceutical Companies Pharmaceuticals 102

Drugs.com

FEBRUARY 28, 2024

WEDNESDAY, Feb. 28, 2024 -- Pesticides and herbicides used in farming appear to increase people’s risk of Parkinson’s disease, a new, preliminary study finds.People exposed to pesticides and herbicides are 25% to 36% more likely to develop.

Disease 104

Disease 104

Advertisement

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

FEBRUARY 28, 2024

Stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of Alzheimer's protein via the brain's glymphatic system, new study suggests.

103

103

Drugs.com

FEBRUARY 28, 2024

WEDNESDAY, Feb. 28, 2024 -- Folks who use marijuana have a greater risk of heart attack and stroke, with the odds rising even higher when they partake every day, a new study finds.Both daily and non-daily marijuana users had an increased risk of.

98

98

SCIENMAG: Medicine & Health

FEBRUARY 28, 2024

“Ovarian cancer (OC) is the third most prevalent type of gynecologic cancer affecting women after cervical and uterine cancer [1]. It is also considered the most fatal of all gynecological cancers […]” Credit: 2024 De Matteis et al.

94

94

Drugs.com

FEBRUARY 28, 2024

WEDNESDAY, Feb. 28, 2024 -- The historic overturning of Roe v. Wade in 2022 has not had any significant effect on the number of abortions performed each month in the United States, new data shows.The #WeCount report tracks abortion rates across.

98

98

Science Daily: Pharmacology News

FEBRUARY 28, 2024

More frequent use of cannabis was associated with higher odds of adverse cardiovascular outcomes, finds new study.

117

117

Drugs.com

FEBRUARY 28, 2024

WEDNESDAY, Feb. 28, 2024 -- Rural homeowners face a greater threat from odorless, radioactive radon gas than people living in urban areas, and it's likely due to the wells they rely on for their water supply, a new study shows.On average, people.

98

98

Science Daily: Pharmacology News

FEBRUARY 28, 2024

Scientists working with data from NASA's James Webb Space Telescope (JWST) have obtained the first full spectra of some of the earliest starlight in the universe. The images provide the clearest picture yet of very low-mass, newborn galaxies, created less than a billion years after the Big Bang, and suggest the tiny galaxies are central to the cosmic origin story.

91

91

Drugs.com

FEBRUARY 28, 2024

WEDNESDAY, Feb. 28, 2024 -- Babies born to mothers who experience profound grief during pregnancy may be vulnerable to heart failure much later in life, new research suggests."If future studies support our findings, the implementation of early.

Research 98

Research 98

SCIENMAG: Medicine & Health

FEBRUARY 28, 2024

Heart, lungs, brain, aorta: elevated to the highest league as an organ Credit: Medical Center – University of Freiburg / Britt Schilling Heart, lungs, brain, aorta: elevated to the highest league as an organ “Recognising the aorta as an organ puts it on a par with the heart, lungs or brain.

87

87

Science Daily: Pharmacology News

FEBRUARY 28, 2024

A genetic change in our ancient ancestors may partly explain why humans don't have tails like monkeys.

112

112

SCIENMAG: Medicine & Health

FEBRUARY 28, 2024

Based on decades-long observations of centenarians, author Dan Buettner (Blue Zones) conjectures that people live longer when they get up and move around after sitting for twenty minutes. Now, a rigorous new study published in the Journal of the American Heart Association (JAHA) has data showing that older women who sat for 11.

84

84

Drugs.com

FEBRUARY 28, 2024

WEDNESDAY, Feb. 28, 2024 -- According to the advocacy group Autism Speaks, one in every 36 U.S. children has an autism spectrum disorder (ASD). Early diagnosis is crucial to helping to treat the condition, but how is a diagnosis done? The U.S.

75

75

SCIENMAG: Medicine & Health

FEBRUARY 28, 2024

Medical University of South Carolina neuroscientist Bashar Badran, Ph.D., was one of only 10 investigators nationwide recognized for their research at the fifth annual scientific meeting of the National Institutes of Health – Helping to End Addiction Long-Term (NIH HEAL) Initiative in Bethesda, Maryland. Badran received an honorable mention for the NIH HEAL Initiative Trailblazer Award.

Research 80

Research 80

BioPharma Drive: Drug Pricing

FEBRUARY 28, 2024

The acquisition of Proof Diagnostics, which was formed to develop a COVID-19 test, gives Ginkgo a library of novel enzymes that can be used to make genetic medicines.

70

70

SCIENMAG: Medicine & Health

FEBRUARY 28, 2024

New York, NY [February 28, 2024]—Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients. Credit: Zhang & Song et al.

Research 74

Research 74

BioPharma Drive: Drug Pricing

FEBRUARY 28, 2024

Shares of the Australian biotech rocketed up about 55% after the company announced results from a mid-stage study in generalized anxiety disorder.

Therapies 73

Therapies 73

SCIENMAG: Medicine & Health

FEBRUARY 28, 2024

Studies at MIT and elsewhere are producing mounting evidence that light flickering and sound clicking at the gamma brain rhythm frequency of 40 Hz can reduce Alzheimer’s disease (AD) progression and treat symptoms in human volunteers as well as lab mice.

Disease 69

Disease Research 69

Drug Patent Watch

FEBRUARY 28, 2024

Annual Drug Patent Expirations for DYMISTA Dymista is a drug marketed by Mylan Speciality Lp and is included in one NDA. It is available from two suppliers. There are four… The post New patent expiration for Mylan Speciality drug DYMISTA appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 59

Drugs Marketing 59

SCIENMAG: Medicine & Health

FEBRUARY 28, 2024

A collaborative research endeavor by scientists in the Departments of Radiology, Neurology, and Psychology and Neuroscience at the UNC School of Medicine have demonstrated the deleterious effects of chronic cocaine use on the functional networks in the brain.

Research 65

Research 65

Drug Patent Watch

FEBRUARY 28, 2024

Annual Drug Patent Expirations for VELSIPITY Velsipity is a drug marketed by Pfizer and is included in one NDA. It is available from two suppliers. There are six patents protecting… The post New patent for Pfizer drug VELSIPITY appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 59

Drugs Marketing 59