Wed.May 08, 2024

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There's a New Set of COVID Variants Called FLiRT: What You Need to Know

Drugs.com

WEDNESDAY, May 8, 2024 -- The virus behind COVID has mutated again, this time producing variants nicknamed FLiRT, the U.S. Centers for Disease Control and Prevention (CDC) has reported.The variants are appearing in wastewater sampling, the CDC.

Virus 130
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Drug patents protect pharma profits. Track when they’ll expire here.

BioPharma Drive: Drug Pricing

Intellectual property is the foundation of the drug industry’s business model. This database will track key patent expiry dates for 30 top-selling medicines.

Drugs 131
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Swarms of miniature robots clean up microplastics and microbes, simultaneously

Science Daily: Pharmacology News

When old food packaging, discarded children's toys and other mismanaged plastic waste break down into microplastics, they become even harder to clean up from oceans and waterways. These tiny bits of plastic also attract bacteria, including those that cause disease. Researchers describe swarms of microscale robots (microrobots) that captured bits of plastic and bacteria from water.

Packaging 123
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AstraZeneca withdraws COVID-19 vaccine, citing declining demand

BioPharma Drive: Drug Pricing

The move ends a turbulent saga for AstraZeneca, which successfully developed a coronavirus shot but struggled to sell it amid competition and the emergence of rare but serious side effects.

Vaccine 120
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Possible atmosphere surrounding rocky exoplanet

Science Daily: Pharmacology News

Researchers may have detected atmospheric gases surrounding 55 Cancri e, a hot rocky exoplanet 41 light-years from Earth. This is the best evidence to date for the existence of any rocky planet atmosphere outside our solar system.

Research 121
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About 90% of U.S. Adults Are On the Way to Heart Disease

Drugs.com

WEDNESDAY, May 8, 2024 -- Nine of 10 American adults are in the early, middle or late stages of a syndrome that leads to heart disease, a new report finds, and almost 10% have the disease already."Poor cardiovascular, kidney, and metabolic health.

Disease 105

More Trending

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Big Rise in Emergencies Involving Synthetic Weed Among Kids, Adults

Drugs.com

WEDNESDAY, May 8, 2024 -- Calls to U.S. poison centers regarding so-called synthetic cannabis jumped 88% between 2021 and 2022, as use of these legally sold products rose, research shows.Synthetic cannabis contain varying forms of the active.

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Rock steady: Study reveals new mechanism to explain how continents stabilized

Science Daily: Pharmacology News

Ancient, expansive tracts of continental crust called cratons have helped keep Earth's continents stable for billions of years, even as landmasses shift, mountains rise and oceans form. A new mechanism may explain how the cratons formed some 3 billion years ago, an enduring question in the study of Earth's history.

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Drive to Be 'Perfect' Parent Isn't Healthy, Survey Finds

Drugs.com

THURSDAY, May 8, 2024 -- Parents striving to be “perfect” will never attain that goal, and the aim isn’t even healthy for their families, a new study says.The risks of striving for perfection are such that researchers have now created a scale.

Research 105
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'Wraparound' implants represent new approach to treating spinal cord injuries

Science Daily: Pharmacology News

A tiny, flexible electronic device that wraps around the spinal cord could represent a new approach to the treatment of spinal injuries, which can cause profound disability and paralysis. A team of engineers, neuroscientists and surgeons developed the devices and used them to record the nerve signals going back and forth between the brain and the spinal cord.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Dogs Brought to U.S. Must Be Microchipped, Older Than 6 Months: CDC

Drugs.com

WEDNESDAY, May 8, 2024 -- Dogs brought into the United States from abroad must be compliant with new rules to help fight rabies in this country, according to updated guidance from the Centers for Disease Control and Prevention issued.

Disease 105
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Children sleep problems associated with psychosis in young adults

Science Daily: Pharmacology News

Children who experience chronic lack of sleep from infancy may be at increased risk of developing psychosis in early adulthood, new research shows.

Research 121
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How CDISC SDTM Improves Cost & Quality in ISS/ISE in 2024

Quanticate

When investigating the efficacy and safety of a new drug/device it is sometimes necessary to combine the research from multiple clinical trials for your analysis. In such cases, it is important to consider the cost and quality of producing integrated summaries and how CDISC SDTM (Clinical Data Interchange Standards Consortium Study Data Tabulation Model) can aid in reducing costs and improving quality for Integrated Summary of Safety (ISS) and Integrated Summary of Efficacy (ISE) submissions.

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Heavy snowfall and rain may contribute to some earthquakes

Science Daily: Pharmacology News

Episodes of heavy snowfall and rain likely contributed to a swarm of earthquakes over the past several years in northern Japan, researchers find. Their study shows climate conditions could initiate some earthquakes.

Research 110
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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How Mindfulness Could Help Folks Quit Opioids

Drugs.com

WEDNESDAY, May 8, 2024 — Using mindfulness to help people trying to overcome opioid addiction can boost their odds of continuing treatment, new research shows.The approach helps folks how to deal with tension, savor life and reframe their.

Treatment 104
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New target for potential leukemia therapy

Science Daily: Pharmacology News

Investigators discovered that a subset of myeloid and lymphoid leukemias depend on a molecular complex called PI3Kgamma for survival. The study provides both mechanistic and preclinical evidence supporting the rapid initiation of clinical trials for patients with acute myeloid leukemia (AML) to test an existing medicine that inhibits the complex, called eganelisib, both alone and in combination with the most used AML chemotherapy, cytarabine.

Therapies 105
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Candy Company Recalls Products Due to Salmonella Risk

Drugs.com

WEDNESDAY, May 8, 2024 -- A Midwestern candy company has issued a massive recall due to the risk of salmonella tainting some of its products.Palmer Candy Company of Sioux City, Iowa, is recalling “white coated confectionary items” because they.

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Chemists produce new-to-nature enzyme containing boron

Science Daily: Pharmacology News

Chemists created an enzyme with boronic acid at its reactive center. This approach can produce more selective reactions with boron, and allows the use of directed evolution to improve its catalytic power.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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How Bad Was Beethoven's Lead Poisoning?

Drugs.com

WEDNESDAY, May 8, 2024 -- No one knows what caused the liver and kidney disease that led to Ludwig van Beethoven’s untimely death.But one popular theory – that high lead levels killed the great composer – should be ruled out, researchers.

Disease 98
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'Mathematical microscope' reveals novel, energy-efficient mechanism of working memory that works even during sleep

Science Daily: Pharmacology News

Researchers have discovered a mechanism that creates memories while reducing metabolic cost, even during sleep. This efficient memory occurs in a part of the brain that is crucial for learning and memory, and where Alzheimer's disease begins.

Disease 98
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Study Finds Heart Damage in 'Couch Potato' Kids

Drugs.com

WEDNESDAY, May 8, 2024 -- Children and young adults who are couch potatoes could wind up with enlarged hearts, increasing their risk of heart attack, stroke and early death.Sedentary behavior contributed as much as 40% to the total increase in.

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A new, low-cost, high-efficiency photonic integrated circuit

Science Daily: Pharmacology News

Researchers have developed scalable photonic integrated circuits, based on lithium tantalate, marking a significant advancement in optical technologies with potential to widespread commercial applications.

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Helping Your Child Make Friends With a Child With Autism

Drugs.com

WEDNESDAY, May 8, 2024 -- Kids are very likely to make the acquaintance of a child diagnosed with autism spectrum disorder at some point, whether they know it or not.

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Which pharmaceutical drugs have the most drug patents in Slovakia?

Drug Patent Watch

This chart shows the drugs with the most patents in Slovakia. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.

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More Than 321,000 U.S. Kids Lost a Parent to Drug ODs in a Decade

Drugs.com

WEDNESDAY, May 8, 2024 -- More than 320,000 U.S. children lost a parent to drug overdose during the past decade, according to a new study reported May 8 in JAMA Psychiatry.What’s more, the death rate accelerated during the period, more than.

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Regeneron gene therapy improves hearing in two children

BioPharma Drive: Drug Pricing

The results add to an early but growing body of evidence suggesting gene therapy may improve outcomes in young kids with a genetic form of deafness.

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Drug Patent Expirations for the Week of May 5, 2024

Drug Patent Watch

DUAVEE (bazedoxifene acetate; estrogens, conjugated) Wyeth pharms Patent: 6,479,535 Expiration: May 6, 2024 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs,… Source

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How does your genetics affect your weight and can drugs help?

Elrig

How does your genetics affect your weight and can drugs help? | Insights from Giles Yeo How does your genetics affect your weight and can drugs help? We were able to have a chat with Giles Yeo, who researches the genetics of body weight, looking at how the brain influences of eating behaviour to find out more. Our brains make decisions on whether or not we should eat from hormone signals which tell it how much fat we currently have stored and what we have recently eaten.

Drugs 59
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Mandatory HTAR Implementation in the EU: Part 2

thought leadership

How ProPharma Can Help You Ensure Compliance with the New HTAR Requirements The new Health Technology Assessment Regulation (HTAR) will set new requirements for pharmaceutical companies seeking registration and market access in the European Union (EU) for their products. This includes preparation and submission of a Joint Clinical Assessment (JCA) report to the European Commission (EC) before product launch.

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New patent for Novartis drug FABHALTA

Drug Patent Watch

Annual Drug Patent Expirations for FABHALTA Fabhalta is a drug marketed by Novartis and is included in one NDA. It is available from one supplier.

Drugs 59
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People Incarcerated in US Jails Receiving Medication for Opioid Use Disorder

Common Sense for Drug Policy Blog

People Incarcerated in US Jails Receiving Medication for Opioid Use Disorder "At midyear 2019, the highest percentage of confined persons receiving MAT was reported in jails in the Northeast (3%), followed by jails in the Midwest and West (1% each) and jails in the South (0.4%) (table 7). Jails in the South accounted for more than half (53%) of the confined jail population at midyear 2019 but nearly a quarter (24%) of jail inmates receiving MAT (not shown in tables).

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Medrio vs Vial | Pros and Cons

Vial

As technological advancements drive the pharmaceutical industry forward, the shift towards digitalization, particularly with electronic data capture (EDC) systems, has become increasingly prominent. The concept of EDC, a computerized system designed to replace paper-based data collection methods, has significantly evolved since its emergence in the early 2000s.

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Announcing Our First Book: Origins

Codon

Our first book, Origins , is now available for purchase. It’s an anthology featuring eight essays, two interviews, and one work of fiction. The book is an ode to scientific progress, and the articles within tell stories about everything from the origins of synthetic biology to the discovery of an antimalarial drug in China and the invention of the micropipette.