Drug Patent Watch

DECEMBER 12, 2024

Identifying branded drugs with a low likelihood of generic entry has become a crucial strategy for companies looking to expand their product portfolio through in-licensing. This approach not only helps maintain market exclusivity but also ensures a steady revenue stream for pharmaceutical companies. In this comprehensive guide, we’ll explore the intricacies of identifying such drugs and leveraging them for successful in-licensing opportunities.

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Licensing Licensing Drugs Biosimilars 90

Chemical Biology and Drug Design

DECEMBER 12, 2024

The inhibitory profile of triaminopyrimidines was expanded and low nM IC 50 alky and aryl variants of CK-1-41 were discovered. Docking supported previous work indicating allosteric inhibition of caspase-1. Analogs with electrophilic warheads were created and inhibited caspase-1 in a partially reversible, time-dependent manner with experimental and docking results supporting allostery.

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Small Molecule Drugs Research 100

addgene Blog

DECEMBER 12, 2024

Prime Editing: Precise and Flexible CRISPR Editing Over 75,000 pathogenic genetic variants have been identified in humans and cataloged in the ClinVar database. Previously developed genome editing methods using nucleases and base editors have the potential to correct only a minority of those variants in most cell types. But prime editing, a CRISPR technique developed in David Lius lab in 2019, has added considerably more precision and flexibility to the CRISPR editing world.

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DNA 98

Perficient: Drug Development

DECEMBER 12, 2024

In today’s digital marketing landscape, delivering personalized and cohesive customer experiences across multiple channels is essential. Salesforce Marketing Cloud Advertising Studio empowers businesses to integrate their advertising efforts with customer data, enabling targeted and effective campaigns. This blog explores the features, benefits, and practical applications of Advertising Studio, providing insights into how it can enhance your marketing strategy.

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Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Drug Patent Watch

DECEMBER 12, 2024

The pharmaceutical industry relies heavily on Contract Development and Manufacturing Organizations (CDMOs) to outsource various stages of drug development and manufacturing. With the increasing complexity of drug development and the need for efficient, cost-effective solutions, selecting the right CDMO is crucial. Evaluating CDMO performance is a critical step in this process, ensuring that the chosen partner can meet the required standards and deliver high-quality products.

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Perficient: Drug Development

DECEMBER 12, 2024

Social media is a pivotal component of any marketing strategy in today’s digital era. Salesforce Marketing Cloud Social Studio offers a comprehensive platform for managing, scheduling, creating, and monitoring social media posts. This enables businesses to effectively engage with their audience and monitor their brand presence across various social channels.

Marketing 52

Marketing 52

Perficient: Drug Development

DECEMBER 12, 2024

Let me take you on a journey. Imagine youre a manager of a large library with books scattered across countless shelves. Some visitors come asking for books by title, others by author, and some want a list of all available books in a specific genre. You cant prepare every possible answer in advance. Instead, you need a system to adapt on the fly to their ever-changing questions.

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Engineering 52

Metabolite Tales Blog

DECEMBER 12, 2024

The Current State of Biotransformation Science Industry Survey of In Vitro and In Vivo Practices, Clinical Translation, and Future Trends To end this year of highlighted papers around the subject of biotransformation and metabolism, we feature a paper published by the Translatability of MetID In Vitro Systems Working Group, a subgroup of the International IQ Consortium.

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Perficient: Drug Development

DECEMBER 12, 2024

Imagine youre a small business owner. Every morning, you log into Salesforce, but instead of spending hours sorting through leads, crafting follow-up emails, and analyzing customer feedback, you find it all done for you. Your CRM didnt just sit thereit worked while you slept. Sounds incredible, right? Welcome to 2025, where Salesforces Einstein GPT is transforming CRM as we know it.

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Marketing Production 52

Drug Channels

DECEMBER 12, 2024

This week, Im rerunning some popular posts while I prepare for tomorrows Drug Channels Outlook 2025 live video webinar. During the webinar, I'll share some thoughts on how vertical integration will affect the buy-and-bill channel. Click here to see the original post from September 2024. Time for DCIs annual update on the channels for provider-administered drugs.

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Specialty Pharmacies Pharmacy Pharmaceuticals Drugs 52

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Perficient: Drug Development

DECEMBER 12, 2024

Welcome to our ongoing series on Universal Design for Healthcare! In this segment, well explore the importance of Visual Disabilities in Healthcare. Universal design for visual disabilities in healthcare is vital for creating an inclusive and equitable system that serves all patients, regardless of their visual abilities. Here are some reasons why it matters: Why Universal Design for Visual Disabilities in Healthcare Matters Promotes Equal Access to Care Universal design ensures that individuals

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Drug Patent Watch

DECEMBER 12, 2024

The generic drug market in the United States faces significant challenges, including price volatility, supply chain disruptions, and strategies employed by brand-name manufacturers to delay market entry. These challenges can lead to drug shortages, price spikes, and reduced affordability for patients and payers. To address these issues, several market-based proposals and regulatory reforms have been suggested.

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Marketing Drugs FDA FDA Approval 52

Perficient: Drug Development

DECEMBER 12, 2024

Welcome to our ongoing series on Universal Design for Healthcare! In this segment, well explore the importance of Visual Disabilities in Healthcare. Creating a healthcare environment that is accessible to individuals with visual disabilities is crucial for delivering equitable and high-quality care. Universal design principles aim to make healthcare facilities, services, and information accessible to all, including those with visual impairments.

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Drug Target Review

DECEMBER 12, 2024

Stem cells often drive our bodies regeneration, with the capacity to differentiate into a myriad of different cell types that can mend or replace ageing or damaged tissue. As result of this unique power, stem cells hold great therapeutic promise. But to realise their full potential in the space, we need to understand and commandeer the epigenetic processes that drive their differentiation.

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Therapies DNA Molecular Biology Immune Response 59

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Advarra

DECEMBER 12, 2024

Selecting an electronic institutional review board (eIRB) system is a critical decision for institutions looking to streamline their research compliance processes. Navigating the eIRB landscape can be overwhelming for researchers, human research protection program (HRPP) team members, and institutions alike. The responsibility to manage submissions, track approvals, and ensure compliance with increasingly complex regulatory standards is a top priority for the research community.

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Compliance Regulations Research Clinical Trials 52