Drug Discovery World
FEBRUARY 2, 2024
Head of clinical trials at the University College London (UCL) Dementia Research Centre, Dr Cath Mummery, has been announced as the Director of a new network of dementia trial sites across the country. The UK government has authorised £49.9 ($63.4) million of new funding to improve access to clinical trials and help accelerate the development of new treatments.
Science Daily: Pharmacology News
FEBRUARY 2, 2024
Fake news works for wallabies and elephants. Herbivores can cause substantial damage to crops or endangered or protected plants, with traditional methods to deter foraging lethal, expensive or ineffective. Biologists are now using aromas from plants naturally repellent with remarkable success to deter the animals.
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Drug Discovery World
FEBRUARY 2, 2024
The DDW team is looking forward to meeting you at SLAS2024, Boston, US on 3-7 February. New for this year is the DDW track at the SLAS Ignite Theater , co-sponsored by Integra Biosciences and Hamamatsu Corporation. Industry experts will share their experiences of how drug discovery technology is driving innovation from bench to bedside. The track is free to attend but spaces are limited.
Chemical Biology and Drug Design
FEBRUARY 2, 2024
Terpenes are compounds that inhibit the growth of Leishmania spp, Schistosoma spp, and Echinococcus spp, cause changes in parasite ultrastructure, inhibit enzyme activity, and modulate the immune response. Their use in combination therapy decreases the concentration of the reference drug used. Abstract Existing chemotherapy for neglected tropical diseases (NTDs) can often be toxic and ineffective, highlighting the necessity for new treatments.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
FEBRUARY 2, 2024
News round-up for 29 January – 2 February by DDW Digital Content Editor Diana Spencer. Sunday 4 February is World Cancer Day, an international awareness day led by the Union for International Cancer Control (UICC), so the round-up this week will focus on oncology, including the UK approval of a rare blood cancer drug and a novel production process for CAR-T therapies.
Antidote
FEBRUARY 2, 2024
Endometrial cancer, also known as endometrial carcinoma or uterine cancer , is a condition that approximately 66,000 individuals are diagnosed with annually, and instances rise roughly 2% in the United States each year. Because it is often caught early, a person’s prognosis is typically good — but it is still a disheartening diagnosis that significantly impacts the lives of those who experience it.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drug Target Review
FEBRUARY 2, 2024
What specific limitations in mirroring diseases in humans are commonly observed when using animal models for preclinical research? The standard animal model paradigm for drug discovery does not translate well to effects in patients for a number of reasons. For one, animal models require disease induction, either genetic or surgical modifications, diet, or application of a disease inducing agent or toxin, yet this is nothing like how diseases progress in humans, which typically take years to deve
Drug Discovery World
FEBRUARY 2, 2024
For this year’s SLAS2024 conference in Boston (which takes place 3-7 February), DDW’s Megan Thomas narrates articles from the DDW SLAS2024 supplement as part of the DDW Events podcast series. This is episode one, called, “A welcome to SLAS 2024”, which includes two comment pieces. Thomas wrote the first one, The journey from lab to patient , which focuses on the theme of the track curated by DDW taking place in the Ignite Theater at SLAS 2024.
Fierce BioTech
FEBRUARY 2, 2024
The annual J.P. Morgan Healthcare Conference is a key date in the industry calendar that is always met with reflection and anticipation. | In this exclusive interview, ICON Biotech President Chris Smyth paints a picture of the operating environment facing biotechs in 2024.
Drug Discovery World
FEBRUARY 2, 2024
NeoPhore has announced a further extension of £9.6 million (approximately $12.2 million) to its Series B financing round, bringing the total raised to £31.1 million (approximately $39.5 million). The company is building a pipeline of small molecule drugs targeting novel proteins across the DNA mismatch repair (MMR) pathway to generate next-generation immuno-oncology therapeutics to improve clinical outcomes for cancer patients.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
BioPharma Drive: Drug Pricing
FEBRUARY 2, 2024
The California biotech is the third this year to go public, following stock offerings from CG Oncology and Arrivent Biopharma.
Drug Discovery World
FEBRUARY 2, 2024
Dr Mike Tarselli , Chief Scientific & Knowledge Officer at TetraScience, was Scientific Director of SLAS until 2020, and will be chairing his first event this year. He shares his insight with Megan Thomas. From pharma to non-profit “I probably wouldn’t have the role I have now if I hadn’t worked for SLAS,” Tarselli reflects. When he first got involved with the organisation, he had been the Associate Director of Novartis for the previous five years.
Drugs.com
FEBRUARY 2, 2024
FRIDAY, Feb. 2, 2024 (HealthDay News) -- Everyone knows someone who gets COVID-19 repeatedly, and they probably also have that annoying friend who's never had the illness. What gives? According to new research, over the long-term it's probably.
Drug Channels
FEBRUARY 2, 2024
Today’s guest post comes from Divya Iyer, SVP of Go-to-Market Strategy at GoodRx. Divya shares highlights from GoodRx’s new research report: The GoodRx Effect: How GoodRx Improves the Economics of Healthcare. She highlights how GoodRx’s integrated pharma copay cards help to improve medication access, therapy adherence, and overall health outcomes. Click here to download the full report and learn more about partnering with GoodRx to drive patient access for your brand.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
FEBRUARY 2, 2024
FRIDAY, Feb. 2, 2024 -- Exercise is crucial to recovering from a stroke, helping victims regain lost physical and mental function.And stroke survivors are more likely to remain physically active -- or even exercise more than before -- if they have.
Covalent Modifiers
FEBRUARY 2, 2024
Seong Ho Hong, Anand Divakaran, Akane Osa, Oscar W. Huang, Ingrid E. Wertz, and Daniel K. Nomura ACS Chemical Biology 2024 DOI: [link] Targeted protein degradation with proteolysis targeting chimeras (PROTACs) is a powerful therapeutic modality for eliminating disease-causing proteins through targeted ubiquitination and proteasome-mediated degradation.
Drugs.com
FEBRUARY 2, 2024
FRIDAY, Feb. 2, 2024 -- Patients who are bleeding out have a better chance of surviving if they’re given whole blood transfusions, a new study shows.Traditionally, patients with significant bleeding are given transfusions of specific blood.
Science Daily: Pharmacology News
FEBRUARY 2, 2024
Do climate change deniers bend the facts to avoid having to modify their environmentally harmful behavior? Researchers ran an online experiment involving 4,000 US adults, and found no evidence to support this idea. The authors of the study were themselves surprised by the results. Whether they are good or bad news for the fight against global heating remains to be seen.
Drugs.com
FEBRUARY 2, 2024
FRIDAY, Feb. 2, 2024 -- It's known by the street name "gas station heroin," but a new government report finds the highly addictive supplement Neptune's Fix may also contain synthetic pot.The product has already been linked to seizures, brain.
SCIENMAG: Medicine & Health
FEBRUARY 2, 2024
Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus Rajewsky from the Max Delbrück Center now report in “Science Immunology.” Credit: Elijah D. Lowenstein and Xun Li, K.
Drugs.com
FEBRUARY 2, 2024
FRIDAY, Feb. 2, 2024 -- Women are much more prone than men to develop autoimmune diseases like rheumatoid arthritis, multiple sclerosis and lupus.Now, researchers have come up with a potential explanation for that -- one that's rooted in genes that.
SCIENMAG: Medicine & Health
FEBRUARY 2, 2024
Clinical trials and medical research have been historically lacking in diversity among all groups. Credit: Hackensack Meridian Health Clinical trials and medical research have been historically lacking in diversity among all groups.
Drugs.com
FEBRUARY 2, 2024
FRIDAY, Feb. 2, 2024 -- Dementia seems like a disorder that’s always haunted the human race.But this form of severe memory loss is actually a modern malady, if classical Greek and Roman physicians are to be believed.A new analysis of ancient.
SCIENMAG: Medicine & Health
FEBRUARY 2, 2024
New York, NY (February 2, 2024) – Clinique and Icahn School of Medicine at Mount Sinai today announced a philanthropic partnership to establish the Mount Sinai-Clinique Healthy Skin Dermatology Center.
Drugs.com
FEBRUARY 2, 2024
FRIDAY, Feb. 2, 2024 -- In some good news for those folks who rolled up their sleeves for the latest COVID vaccine last fall, new government research shows the updated shots halve the chances of getting a symptomatic infection.“Everything from.
SCIENMAG: Medicine & Health
FEBRUARY 2, 2024
With a $300,000 grant, the Welch Foundation is supporting University of Texas at Arlington research into why some types of Mycobacterium tuberculosis (Mtb), the bacteria that causes the lung disease tuberculosis (TB), do not respond to treatments.
Drugs.com
FEBRUARY 2, 2024
FRIDAY, Feb. 2, 2024 -- It might take a combination of treatments to rein in problem acne in teens and adults, updated guidelines from the American Academy of Dermatology (AAD) suggest.The guidelines on the all-too-common condition (acne affects.
Science Daily: Pharmacology News
FEBRUARY 2, 2024
Astronomers have shown new atmospheric detail in a set of 15 exoplanets similar to Neptune. While none could support humanity, a better understanding of their behavior might help us to understand why we don't have a small Neptune, while most solar systems seem to feature a planet of this class.
Drugs.com
FEBRUARY 2, 2024
FRIDAY, Feb. 2, 2024 -- Advanced brain recording techniques have revealed how neurons in the human brain work together to produce speech.The recordings provide a detailed map of how people think about what words they want to say and then speak them.
BioPharma Drive: Drug Pricing
FEBRUARY 2, 2024
A regulatory filing shows the firm is putting together a new multibillion-dollar fund, roughly two years after raising a similar amount.
Drugs.com
FEBRUARY 2, 2024
FRIDAY, Feb. 2, 2024 -- For stroke survivors, the relative affluence of their neighborhood could be a factor in how well and how soon they recover, new research shows.Compared to Americans living in better-off locales, those living in areas plagued.
Drug Patent Watch
FEBRUARY 2, 2024
Annual Drug Patent Expirations for UBRELVY Ubrelvy is a drug marketed by Abbvie and is included in one NDA. It is available from one supplier. There are six patents protecting… The post New patent for Abbvie drug UBRELVY appeared first on DrugPatentWatch - Make Better Decisions.
Drugs.com
FEBRUARY 2, 2024
FRIDAY, Feb. 2, 2024 -- The heavy lead apron dentists drape over you during dental X-rays may soon be a thing of the past.
Drug Patent Watch
FEBRUARY 2, 2024
Annual Drug Patent Expirations for ANNOVERA Annovera is a drug marketed by Mayne Pharma and is included in one NDA. It is available from one supplier. There are seven patents… The post New patent for Mayne Pharma drug ANNOVERA appeared first on DrugPatentWatch - Make Better Decisions.
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