Drug Discovery World
JUNE 26, 2024
The DDW Summer issue looks at where the global biotech hubs are for drug discovery and development, asks how 3D genomics can accelerate personalised medicine, and looks at the technological advances in mass spectrometry. It also includes an exclusive global cancer research guide examining the innovation happening in this sector. DDW Summer 2024 The post DDW Summer 2024 appeared first on Drug Discovery World (DDW).
Science Daily: Pharmacology News
JUNE 26, 2024
A new study documents the first case of Down syndrome in Neanderthals and reveals that they were capable of providing altruistic care and support for a vulnerable member of their social group.
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Drug Discovery World
JUNE 26, 2024
Spinogenix has initiated a Phase II trial to evaluate SPG302 for the treatment of adult participants with mild-to-moderate Alzheimer’s disease (AD), following approval for the trail in Australia. The study will assess the safety, tolerability, pharmacokinetics, pharmacodynamics and clinical efficacy of SPG302 in adult AD participants. The clinical trial will consist of two parts: a pilot, placebo-controlled, randomised safety and preliminary efficacy cohort (Part A) and an expansion cohort (Part
BioPharma Drive: Drug Pricing
JUNE 26, 2024
Obesity drugs like Wegovy are proving useful in many other diseases. Polycystic ovary syndrome, a chronic condition that can cause infertility, may be one.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
JUNE 26, 2024
Scientists at the University of Bristol have uncovered a new disease driving mechanism which they are aiming to target to help treat the development of atherosclerotic plaques. The project to develop the new therapeutic, known as IMSET, is being led by Professor Jason Johnson, Professor of Cardiovascular Pathology within the Bristol Medical School. Following successful initial testing, the team have been awarded substantial funding through the beLAB1407 BRIDGE partnership to continue developing
Science Daily: Pharmacology News
JUNE 26, 2024
A new study by a team of international researchers has uncovered a biological explanation for long-term memories. It centers on the discovery of the role of a molecule, KIBRA, that serves as a 'glue' to other molecules, thereby solidifying memory formation.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
JUNE 26, 2024
Early analysis of the asteroid Bennu sample returned by NASA's OSIRIS-REx mission has revealed dust rich in carbon, nitrogen, and organic compounds, all of which are essential components for life as we know it. Dominated by clay minerals, particularly serpentine, the sample mirrors the type of rock found at mid-ocean ridges on Earth. The magnesium-sodium phosphate found in the sample hints that the asteroid could have splintered off from an ancient, small, primitive ocean world.
Drug Discovery World
JUNE 26, 2024
Biotechnology company EG 427 has revealed plans to start a Phase Ib/IIa clinical study in neurogenic detrusor overactivity (NDO), following Investigational New Drug (IND) clearance from the US Food and Drug Administration (FDA). NDO is a severe bladder condition affecting patients living with spinal cord injury, multiple sclerosis, Parkinson’s disease and other neurological disorders.
BioPharma Drive: Drug Pricing
JUNE 26, 2024
The findings provide early proof that multiple doses of a gene editing medicine can be safely administered with additive effects, overcoming a key constraint of the complex therapies.
Drug Discovery World
JUNE 26, 2024
Learn about the key principles, methodologies and regulatory requirements of drug stability testing with our recently developed eBook: ‘Drug Stability Testing 101’ This eBook has been prepared by scientists and industry professionals at Thermo Fisher Scientific to provide you with valuable insights and practical knowledge to help you optimise this critical aspect of pharmaceutical development with the new Thermo Scientific™ Heratherm™Environmental Chambers.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
JUNE 26, 2024
Scientists predict from geochemical data that Iceland is entering a new volcanic era that will last for decades, possibly centuries. Under an hour's drive from the country's capital city, the ongoing eruptions pose considerable risks for economic disruption, and they leave evacuated communities uncertain of a possible return.
Drug Discovery World
JUNE 26, 2024
Learn about the key principles, methodologies and regulatory requirements of drug stability testing in a new eBook from Thermo Fisher Scientific: ‘ Drug Stability Testing 101 ‘ The eBook has been prepared by scientists and industry professionals to provide readers with valuable insights and practical knowledge to help optimise this critical aspect of pharmaceutical development with the new Thermo Scientific Heratherm Environmental Chambers.
Science Daily: Pharmacology News
JUNE 26, 2024
Researchers continue to expand the case for the Younger Dryas Impact hypothesis. The idea proposes that a fragmented comet smashed into the Earth's atmosphere 12,800 years ago, causing a widespread climatic shift that, among other things, led to the abrupt reversal of the Earth's warming trend and into an anomalous near-glacial period called the Younger Dryas.
Drug Discovery World
JUNE 26, 2024
The first episode of the DDW From the Top vodcast features Dr Rohan Thakur, President of Bruker Daltonics, as part of the From the Top vodcast series. Dr Thakur discusses the intersection of science and business, sharing his experiences and insights on how to navigate this intersection. He reflects on his career path, highlighting key moments and milestones, and expresses gratitude for the opportunities he has had.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
JUNE 26, 2024
WEDNESDAY, June 26, 2024 -- A federal health advisory warning of a heightened risk of dengue fever infections in the United States was issued on Tuesday.The alert was prompted by an unexpectedly high number of dengue fever cases reported across the.
Drug Patent Watch
JUNE 26, 2024
This is an example from the DrugPatentWatch AI Research Assistant, which is available with DrugPatentWatch subscriptions. The DrugPatentWatch AI Research Assistantuses sophisticated AI algorithms to understand and process your questions, delivering precise answers. It goes beyond simple keyword matching, comprehending the intent and context of questions to provide meaningful and relevant responses.
Science Daily: Pharmacology News
JUNE 26, 2024
Researchers are reporting progress on the road to more efficient utilization of solar energy: They have developed an innovative light-harvesting system.
Drug Patent Watch
JUNE 26, 2024
Introduction In the rapidly evolving landscape of pharmaceutical patent disputes in China, injunctive relief has emerged as a critical tool for patent holders. This legal remedy, which aims to halt infringement activities swiftly, plays a pivotal role in protecting intellectual property (IP) rights and fostering innovation.
FDA Law Blog: Biosimilars
JUNE 26, 2024
By Lisa M. Baumhardt, Senior Medical Device Regulation Expert & Adrienne R. Lenz, Principal Medical Device Regulation Expert — FDA recently released a new eSTAR template for device pre-submissions and 513(g) Requests for Information, referred to as PreSTAR. A pre-submission provides the submitter an opportunity to obtain FDA feedback prior to a planned medical device premarket submission.
Drugs.com
JUNE 26, 2024
WEDNESDAY, June 26, 2024 -- A tough-to-treat, drug-resistant fungal infection may be as close as your local garden center, new research shows.Investigators at the University of Georgia (UGA) in Athens found high levels of multidrug-resistant fungi.
Science Daily: Pharmacology News
JUNE 26, 2024
Researchers have projected future marine heatwaves will cause coral reefs to be at severe risk of bleaching for longer periods than previously seen.
Drugs.com
JUNE 26, 2024
WEDNESDAY, June 26, 2024 -- The stress hormone cortisol appears to play a role in tough-to-treat type 2 diabetes, a new study finds.About 1 in 4 people (24%) with tough-to-treat type 2 diabetes have elevated cortisol levels, researchers.
Science Daily: Pharmacology News
JUNE 26, 2024
Researchers have identified the likeliest timeline of the famous Hellenistic-era Kyrenia shipwreck, discovered and recovered off the north coast of Cyprus in the 1960s.
Drugs.com
JUNE 26, 2024
WEDNESDAY, June 26, 2024 -- Mothers tend to speak less to infants when they’re on their smartphones, a new study finds.Moms talked 16% less to their babies when they were fiddling with their phone, researchers found.Shorter 1- to 2-minute intervals.
BioPharma Drive: Drug Pricing
JUNE 26, 2024
The failure of a Phase 3 trial led the Wegovy maker to take an accounting charge that will hit its operating profit growth this year.
Drugs.com
JUNE 26, 2024
WEDNESDAY, June 26, 2024 -- A common plastics chemical might increase a person’s risk of diabetes, a new study warns.People fed small doses of Bisphonol A (BPA) developed significantly worse insulin sensitivity within a four-day period, researchers.
Science Daily: Pharmacology News
JUNE 26, 2024
Engineers have developed a pill that releases microscopic robots, or microrobots, into the colon to treat inflammatory bowel disease (IBD). The experimental treatment, given orally, has shown success in mice. It significantly reduced IBD symptoms and promoted the healing of damaged colon tissue without causing toxic side effects.
Drugs.com
JUNE 26, 2024
WEDNESDAY, June 26, 2024 -- A full third of American adults take multivitamins, despite prior studies suggesting they do little to boost health.Now, a study involving almost 400,000 people finds zero benefit from multivitamin use in helping folks.
Quanticate
JUNE 26, 2024
Clinical Data Interchange Standards Consortium (CDISC) defines and manages industry level data standards that are widely used during the analysis, reporting and the regulatory submission of clinical data. There are three key CDISC standards which are vital for efficient data processing and analysis of clinical trial data known as CDASH , SDTM and ADaM.
Drugs.com
JUNE 26, 2024
WEDNESDAY, June 26, 2024 -- Post-Dobbs bans and restrictions on abortion are having a spillover effect in reducing the use of birth control and emergency contraception in those states most affected, a new study shows.Why the troubling trend? The.
Science Daily: Pharmacology News
JUNE 26, 2024
Researchers have developed a kirigami-inspired mechanical computer that uses a complex structure of rigid, interconnected polymer cubes to store, retrieve and erase data without relying on electronic components. The system also includes a reversible feature that allows users to control when data editing is permitted and when data should be locked in place.
Drugs.com
JUNE 26, 2024
WEDNESDAY, June 26, 2024 -- Anxiety could be an early warning sign of Parkinson's disease, a new study finds.People with anxiety have at least double the risk of developing Parkinson’s compared to those without the mood disorder, results s.
Science Daily: Pharmacology News
JUNE 26, 2024
A large analysis of data from nearly 400,000 healthy U.S. adults followed for more than 20 years has found no association between regular multivitamin use and lower risk of early death.
Drugs.com
JUNE 26, 2024
WEDNESDAY, June 26, 2024 -- A person’s gut microbiome appears to increase their risk of developing type 2 diabetes, researchers claim.Specific strains of gut microbes are more commonly found in people with type 2 diabetes, and these strains seem to.
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