Drug Discovery World

NOVEMBER 28, 2023

An international team of scientists has shown that a stem cell therapy for multiple sclerosis (MS) could prevent further damage to the brain. The early-stage clinical trial was the result of a collaboration between researchers at University of Colorado Anschutz Campus, the University of Cambridge and the University of Milano-Bicocca. “We don’t know yet whether this is the beginning of a fantastic journey or not, but the results are very strong and very consistent,” said Professor Stefano Pluchin

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BioPharma Drive: Drug Pricing

NOVEMBER 28, 2023

U.S. tax law changes enacted six years ago slashed large pharma companies' rates and saved them billions. Now, a push for an international floor could disrupt their R&D accounting.

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Drug Discovery World

NOVEMBER 28, 2023

In the eighth eBook of the Hamilton series, ‘Assessing the Efficacy of Vaccines through Laboratory Assays’, we discuss: Vaccine development: Key milestones and impact of Covid-19 Laboratory tests commonly used to assess vaccines’ efficacy and the benefits of automating them Hamilton standardised and customised solutions for workflows such as qPCR, NGS, ELISA/ELISpot and virus-neutralisation assays The post Assessing the efficacy of vaccines through laboratory assays appeared fi

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BioPharma Drive: Drug Pricing

NOVEMBER 28, 2023

The agency said the benefit of approved treatments like Gilead’s Yescarta still outweighs any such risk, but the alert could slow drugmaker efforts to develop the treatments for wider use.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

NOVEMBER 28, 2023

The eighth eBook of the Hamilton series is now available to download for free. In ‘ Assessing the Efficacy of Vaccines through Laboratory Assays ‘, the authors discuss the key milestones achieved throughout the history of vaccine development, the laboratory tests commonly used to assess vaccines’ efficacy, and we describe how the latter can be automated using Hamilton solutions.

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Laboratories Vaccine Virus Drugs 130

Drugs.com

NOVEMBER 28, 2023

TUESDAY, Nov. 28, 2023 -- Stem cells injected into the brains of multiple sclerosis patients appear to protect them against further damage from the degenerative disease, a new study shows.MS occurs when the body’s own immune system attacks and.

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Therapies Disease 119

Drugs.com

NOVEMBER 28, 2023

TUESDAY, Nov. 28, 2023 -- It might seem that surfing the web could cause a person’s mental health to suffer, but a landmark new study has concluded that internet use poses no major threat to people’s psychological well-being.Researchers.

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Science Daily: Pharmacology News

NOVEMBER 28, 2023

Researchers have discovered a new relationship between the Sun's magnetic field and its sunspot cycle, that can help predict when the peak in solar activity will occur. Their work indicates that the maximum intensity of solar cycle 25, the ongoing sunspot cycle, is imminent and likely to occur within a year.

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Research 109

Drugs.com

NOVEMBER 28, 2023

TUESDAY, Nov. 28, 2023 -- Personal trainers can help people increase their strength and their fitness.Could a “brain coach” be just as useful in preventing Alzheimer’s’ disease?A new study suggests that personalized health and lifestyle.

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Disease 110

Perficient: Drug Development

NOVEMBER 28, 2023

On Operational projects that involves heavy data volume load on a daily basis, there’s a need to monitor the DB Disk Space availability. Over a period of time, the size grows occupying the disk space. While there are best practices to handle the size by adopting strategies of Purge for outdated data and add buffer/temp/data/log space to address the growing needs, it is necessary to be aware of the Disk space and consistently monitor for further actions.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

NOVEMBER 28, 2023

TUESDAY, Nov. 28, 2023 — Medical imaging for thinking and memory issues happens much later in Black patients than in their white and Hispanic counterparts, new research shows.A study to be presented Thursday at a meeting of radiologists also.

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Research 109

Science Daily: Pharmacology News

NOVEMBER 28, 2023

One voice does not fit all when it comes to virtual assistants like Siri and Alexa, according to researchers who examined how customization and perceived similarity between user and voice assistant (VA) personalities affect user experience. They found a strong preference for extroverted VAs -- those that speak louder, faster and in a lower pitch. They also found that increasing personality similarity by automatically matching user and VA voice profiles encouraged users to resist persuasive infor

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Research 102

Drugs.com

NOVEMBER 28, 2023

TUESDAY, Nov. 28, 2023 -- Evidence that soccer heading -- where players use their heads to strike a ball -- is dangerous continues to mount.Research to be presented at the Radiological Society of North America (RSNA) annual meeting in Chicago on.

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Drug Channels

NOVEMBER 28, 2023

I hope everyone enjoyed the Thanksgiving holiday. Now that you’ve stretched your stomach, it's time to stretch your mind with some food for thought. In this issue: A reality check on Express Scripts’ purported “cost-based” pharmacy network Mark Cuban explains how and why the PBM market will change Why two drug prices are better than one Pharmacists sing the retail pharmacy shakeout blues Plus, two Philly legends meet at a cardiology conference!

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Pharmacy Drugs Marketing 97

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

NOVEMBER 28, 2023

TUESDAY, Nov. 28, 2023 (Healthday News) -- The prevalence of a highly mutated COVID variant has tripled in the past two weeks, new government data shows.Now, nearly 1 in 10 new COVID cases are fueled by the BA.2.86 variant, the U.S. Centers for.

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Government 105

SCIENMAG: Medicine & Health

NOVEMBER 28, 2023

Digital Science, a technology company serving stakeholders across the research ecosystem, is pleased to announce that Louisiana State University Health Shreveport (LSUHS) has chosen Dimensions Analytics and Dimensions Research Security from Digital Science’s flagship products to advance its world-class research programs.

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Science Research Production 91

Science Daily: Pharmacology News

NOVEMBER 28, 2023

Researchers have provided new insights into how ancestral elephants developed their dextrous trunks. A study of the evolution of longirostrine gomphotheres, an ancestor of the modern day elephant, suggests moving into open-land grazing helped develop their coiling and grasping trunks.

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Research 90

SCIENMAG: Medicine & Health

NOVEMBER 28, 2023

A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) Volume 15, Issue 21, entitled, “1,5-anhydro-D-fructose induces anti-aging effects on aging-associated brain diseases by increasing 5’-adenosine monophosphate-activated protein kinase activity via the peroxisome proliferator-activated receptor-γ co-activator-1α/brain-derived neurotrophic factor pathway.

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Disease Science Research 89

Drugs.com

NOVEMBER 28, 2023

TUESDAY, Nov. 28, 2023 -- COVID vaccines saved the lives and health of countless babies by preventing their premature births, a new study shows.COVID-19 initially caused an alarming surge in premature birth rates, but those returned to pre-pandemic.

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Vaccine 86

SCIENMAG: Medicine & Health

NOVEMBER 28, 2023

A research group led by Nagoya University’s Graduate School of Engineering has uncovered how rapid tendon regeneration occurs in newts. The research, published in the Journal of Orthopaedic Research, compared the regeneration mechanism of damaged tendons in newts with those in mice.

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Engineering Research 89

LifeSciVC

NOVEMBER 28, 2023

By Jeb Keiper, CEO of Nimbus Therapeutics, as part of the From The Trenches feature of LifeSciVC. @JebKeiper Earlier this year, Nimbus closed the sale of our allosteric TYK2 program, which was acquired by Takeda for $4 billion upfront. To say 2023 has been an excellent year for Nimbus would be an understatement and by some standards, the best of our 14-year history (more here ).

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SCIENMAG: Medicine & Health

NOVEMBER 28, 2023

AMES, Iowa – A research poster dated Dec. 9, 2015, hangs just outside Nicole Hashemi’s Iowa State University laboratory. It introduces a major project for Hashemi and her research group. And it’s evidence that scientific persistence sometimes equals scientific advancement. Credit: Photo by Christopher Gannon/Iowa State University. AMES, Iowa – A research poster dated Dec.

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Science Daily: Pharmacology News

NOVEMBER 28, 2023

Engineers have come up with a new way to teach robots to know when they don't know. The technique involves quantifying the fuzziness of human language and using that measurement to tell robots when to ask for further directions. Telling a robot to pick up a bowl from a table with only one bowl is fairly clear. But telling a robot to pick up a bowl when there are five bowls on the table generates a much higher degree of uncertainty -- and triggers the robot to ask for clarification.

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Engineering 84

SCIENMAG: Medicine & Health

NOVEMBER 28, 2023

ATLANTA — Two leading researchers in the Institute for Biomedical Sciences at Georgia State University have been ranked in the top 1 percent worldwide by citations for their field and publication year in the Web of Science database, according to the Highly Cited Researchers 2023 list by Clarivate.

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BioPharma Drive: Drug Pricing

NOVEMBER 28, 2023

Fresh off a $7 billion deal with Roche, the chief executive spoke with BioPharma Dive about this year’s “discordant combination” of major biotech achievements alongside market headwinds.

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Marketing 76

SCIENMAG: Medicine & Health

NOVEMBER 28, 2023

A five-year, $2 million grant to study the pharmacological effects of the areca nut, commonly known as the betel nut, was awarded to a UTHealth Houston researcher by the National Institute on Drug Abuse, part of the National Institutes of Health (NIH).

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Science Daily: Pharmacology News

NOVEMBER 28, 2023

Asteroid Phaethon, which is five kilometers in diameter, has been puzzling researchers for a long time. A comet-like tail is visible for a few days when the asteroid passes closest to the Sun during its orbit. However, the tails of comets are usually formed by vaporizing ice and carbon dioxide, which cannot explain this tail. The tail should be visible at Jupiter's distance from the Sun.

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Perficient: Drug Development

NOVEMBER 28, 2023

At the beautiful Shinola Hotel in downtown Detroit, we invited a distinguished group of automotive and mobility industry leaders to participate in a discussion on the current state of the industry. The conversation was lively, and we traded ideas, theories, and suggestions on how OEMs and automotive suppliers could thrive in this changing industry. The two main topics we covered in an hour-long conversation were electric vehicles and the evolving commerce landscape in automotive.

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Science Daily: Pharmacology News

NOVEMBER 28, 2023

Taking into account whether people believe they are receiving a real treatment or a fake one (placebo) could provide better insights that could help improve interventions for conditions such as depression and ADHD.

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Drugs.com

NOVEMBER 28, 2023

TUESDAY, Nov. 28, 2023 -- Transgender people transitioning to male (transmasculine) identity typically take testosterone therapy as part of the process. There have been worries that the treatment might spur erythrocytosis, an abnormally high.

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Therapies Treatment 64

Science Daily: Pharmacology News

NOVEMBER 28, 2023

Scientists are warning that apparently stable glaciers in the Antarctic can 'switch very rapidly' and lose large quantities of ice as a result of warmer oceans. Their finding comes after glaciologists used satellites to track the Cadman Glacier, which drains into Beascochea Bay, on the west Antarctic peninsula.

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Drugs.com

NOVEMBER 28, 2023

TUESDAY, Nov. 28, 2023 -- Folks who smoke weed along with cigarettes are doing serious damage to their lungs, a new study warns.People who do both are 12 times more likely to develop emphysema than nonsmokers, due to the damage they’re doing to.

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FDA Law Blog: Biosimilars

NOVEMBER 28, 2023

By Allyson B. Mullen & Jeffrey N. Gibbs — Shortly before the Thanksgiving holiday, FDA announced with no fanfare that it would be holding a Molecular and Clinical Genetics Panel meeting this Wednesday November 29. The notice ( here ) indicates that FDA plans for the panel to “discuss and make recommendations on the design of multi-cancer detection (MCD) in vitro diagnostic devices (tests) as well as potential study designs and study outcomes of interest that could inform the assessment of t

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Science Daily: Pharmacology News

NOVEMBER 28, 2023

Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists -- so far. A new multi-chamber organoid that mirrors the heart's intricate structure enables scientists to advance screening platforms for drug development, toxicology studies, and understanding heart development.

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