BioPharma Drive: Drug Pricing
SEPTEMBER 26, 2024
In testing, Cobenfy eased schizophrenia symptoms without some of the disruptive side effects typical of existing drugs. The results have been met with excitement, as well as caution.
Chemical Biology and Drug Design
SEPTEMBER 26, 2024
Compound 22 might become a novel antioxidant for the treatment of oxidative stress-related diseases. ABSTRACT Paeoniflorin (PF) is one of the active constituents of the traditional Chinese medicine Paeoniae Radix Rubra and has been actively explored in the pharmaceutical area due to its numerous pharmacological effects. However, severe difficulties such as limited bioavailability and low permeability limit its utilization.
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BioPharma Drive: Drug Pricing
SEPTEMBER 26, 2024
Despite working in a restrictive funding climate, the prolific startup creator is “in the ‘taking lots of risk’ mode,” said co-founder and managing director Robert Nelsen.
Science Daily: Pharmacology News
SEPTEMBER 26, 2024
Researchers have discovered a new bacterium that weakens the immune system in the gut, potentially contributing to certain inflammatory and infectious gut diseases. The team identified the bacterium, Tomasiella immunophila (T. immunophila), which plays a key role in breaking down a crucial immune component of the gut's multi-faceted protective immune barrier.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
SEPTEMBER 26, 2024
THURSDAY, Sept. 25, 2024 -- A new gene therapy approved earlier this year can serve as a sustainable single-dose treatment for people with hemophilia B, newly published clinical trial data shows. People with hemophilia B saw their bleeding episodes.
Science Daily: Pharmacology News
SEPTEMBER 26, 2024
Sea robins are unusual animals with the body of a fish, wings of a bird, and walking legs of a crab. Now, researchers show that the legs of the sea robin aren't just used for walking. In fact, they are bona fide sensory organs used to find buried prey while digging.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
SEPTEMBER 26, 2024
Compared with inactivity, a weekend warrior pattern of exercise (concentrating most moderate-to-vigorous physical activity in one to two days during the week) or a more evenly distributed physical activity pattern were associated with similarly lower risks of diseases across 16 categories -- from heart and digestive conditions to mental health and neurological illnesses.
Perficient: Drug Development
SEPTEMBER 26, 2024
The energy was electric last week as thousands of attendees invaded MGM Grand along the Las Vegas Strip for the 3rd Annual Power Platform Community Conference (PPCC24). From groundbreaking announcements to new features unveiled during keynotes from Microsoft’s Charles Lamanna, Corporate Vice President of Business Industry and Copilot, and Jeff Teper, President of Apps and Platforms, PPCC24 offered an electrifying three days of innovation and collaboration.
Drugs.com
SEPTEMBER 26, 2024
THURSDAY, Sept. 26, 2024 -- Four out of five pregnant women will become deficient in an essential nutrient, iron, by their third trimester, a new study finds.The researchers and other experts are now advocating that iron levels be routinely checked.
Science Daily: Pharmacology News
SEPTEMBER 26, 2024
Astronomers have published a gigantic infrared map of the Milky Way containing more than 1.5 billion objects -- the most detailed one ever made. Using the European Southern Observatory's VISTA telescope, the team monitored the central regions of our Galaxy over more than 13 years. At 500 terabytes of data, this is the largest observational project ever carried out with an ESO telescope.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
SEPTEMBER 26, 2024
THURSDAY, Sept. 26, 2024 -- “Body roundness” could be a better measure than BMI at predicting how excess weight might affect a person’s heart health, a new study finds.People who developed a high Body Roundness Index during a six-year period had a 1.
Science Daily: Pharmacology News
SEPTEMBER 26, 2024
In a surprise finding, astronomers using NASA's Hubble Space Telescope have discovered that the blowtorch-like jet from a supermassive black hole at the core of a huge galaxy seems to cause stars to erupt along its trajectory. The stars, called novae, are not caught inside the jet, but apparently in a dangerous neighborhood nearby.
Drugs.com
SEPTEMBER 26, 2024
THURSDAY, Sept. 26, 2024 -- -- The Environmental Protection Agency must address concerns about potential health risks posed by the recommended levels of fluoride in the country's drinking water, a federal court in California has ruled.While.
Science Daily: Pharmacology News
SEPTEMBER 26, 2024
A 2020 microlensing event was caused by a planetary system with an Earth-like planet and brown dwarf. The star type was uncertain. The team has determined that the star is a white dwarf, a system resembling what our sun-Earth system will look like in 8 billion years. The good news: the planet survived its star's red giant phase, so maybe Earth will too.
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Drugs.com
SEPTEMBER 26, 2024
THURSDAY, Sept. 25, 2024 -- A new gene therapy approved earlier this year can serve as a sustainable single-dose treatment for people with hemophilia B, newly published clinical trial data shows.People with hemophilia B saw their bleeding episodes.
Drug Patent Watch
SEPTEMBER 26, 2024
The generic drug market is a complex and dynamic environment where multiple factors influence the availability, quality, and pricing of generic drugs. Conducting an effective market analysis is crucial for pharmaceutical companies, policymakers, and healthcare professionals to understand the market dynamics and make informed decisions.
Drugs.com
SEPTEMBER 26, 2024
FRIDAY, Sept. 27, 2024 -- Chroming, where toxic fumes from common household items are inhaled for a quick high, is on the rise among youth and TikTok may be to blame, new research suggests.In findings that are to be presented Saturday at the.
Science Daily: Pharmacology News
SEPTEMBER 26, 2024
Using mathematical modeling, researchers found a way to maintain cooperation without relying on complex norms or institutions.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
SEPTEMBER 26, 2024
THURSDAY, Sept. 26, 2024 -- Starting today, the U.S. government is offering another round of free COVID tests."U.S. households will be eligible to order 4 free COVID-19 tests at COVIDTests.gov," according to the Department of Health and Human.
Science Daily: Pharmacology News
SEPTEMBER 26, 2024
Spontaneous injuries like the loss of a limb or damage to the spinal cord are impossible for humans to repair. Yet, some animals have an extraordinary capacity to regenerate after injury, a response that requires a precise sequence of cellular events. Now, new research has unveiled a critical timing factor -- specifically how long cells actively respond to injury -- involved in regulating regeneration.
Drugs.com
SEPTEMBER 26, 2024
THURSDAY, Sept. 26, 2024 -- U.S. suicide rates are ticking back upward again after a dip during the pandemic, new statistics show.Suicide deaths per 100,000 people had fallen from 14.2 recorded in the pre-pandemic year of 2018 to 13.5 in 2020.
BioPharma Drive: Drug Pricing
SEPTEMBER 26, 2024
The withdrawal comes as trial results indicate safety concerns with the drug, Oxbryta, which was first approved in the U.S. in 2019.
Drugs.com
SEPTEMBER 26, 2024
THURSDAY, Sept. 26, 2024 -- There’s good news for folks who struggle to fit regular exercise into their busy workweek.“Weekend warrior” workouts are just as beneficial as daily exercise to a person’s overall health, a new study says.People who get a.
DrugBank
SEPTEMBER 26, 2024
Biosimilars Biosimilars, while highly similar to their reference biopharmaceuticals, offer distinct advantages that position them as preferred therapeutic options in many cases. The primary advantage is cost-effectiveness. Due to the less extensive clinical trial requirements and the competitive nature of the biosimilar market, these biologics can be produced and marketed at significantly lower prices than their reference counterparts.
Drugs.com
SEPTEMBER 26, 2024
THURSDAY, Sept. 26, 2024 -- Brain damage that veterans suffered from flying shrapnel has provided a major clue that could lead to better treatment for post-traumatic stress disorder (PTSD), a new study says.Veterans who suffered shrapnel damage.
addgene Blog
SEPTEMBER 26, 2024
If cloning methods had personalities, SLIC (sequence- and ligation-independent cloning) would be a true rebel. Not only does this system not use site-specific recombination, it also doesn’t require a ligation step. Based on the robust system of homologous recombination found in E. coli , SLIC is a cheap, standardized, and rapid multi-part DNA assembly method.
Drugs.com
SEPTEMBER 26, 2024
FRIDAY, Sept. 27, 2024 -- Laws that ban assault weapons do indeed protect children from dying in mass shootings, but the same can't be said for more common types of gun restrictions and regulations, new research shows.“Mass shootings are horrific e.
Science Daily: Pharmacology News
SEPTEMBER 26, 2024
A team has designed a new drug against malaria and identified its mechanism of action.
Drugs.com
SEPTEMBER 26, 2024
THURSDAY, Sept. 26, 2024 -- There's been one more death linked to listeria illness from tainted deli meats made by Boar's Head, bringing the death toll to 10.The latest update from the U.S. Centers for Disease Control and Prevention recorded an.
Drug Target Review
SEPTEMBER 26, 2024
Cresset delivers software solutions and contract research expertise enabling companies around the world to accelerate their small molecule discovery processes efficiently and effectively. Customers include the pharmaceutical, biotechnology and agrochemical industries. Dr Mutlu Dogruel is the VP of AI Solutions, who has outlined a forward-thinking vision to revolutionise drug discovery processes by integrating cutting-edge AI technologies to enhance productivity, streamline workflows, and empower
Drugs.com
SEPTEMBER 26, 2024
THURSDAY, Sept. 26, 2024 -- As people living near airports probably already know, all that overhead traffic can take a huge hit to their sleep, a new study confirms.Night-time aircraft noise increases a person’s risk of tossing and turning in bed a.
FDA Law Blog: Biosimilars
SEPTEMBER 26, 2024
By Jennifer D. Newberger — We can all acknowledge that the title of this post is not that funny-at least, not to anyone other than medical device regulatory nerds, such as the author of this post. What no one should find funny is how CDRH seems to be approaching Breakthrough devices of late, setting clinical study expectations so high that these innovative, novel, life-saving products may never get to the other side of the door, regardless of how much they knock.
Covalent Modifiers
SEPTEMBER 26, 2024
Changliu Wang, Zhenguang Zhao, Reem Ghadir, Dechun Yang, Zhenjia Zhang, Zhe Ding, Yuan Cao, Yuqing Li, Rosi Fassler, Dana Reichmann, Yujie Zhang, Yongli Zhao, Can Liu, Xiaobao Bi, Norman Metanis, and Junfeng Zhao ACS Central Science 2024 10 (9), 1742-1754 DOI: 10.1021/acscentsci.4c01148 Efficient functionalization of peptides and proteins has widespread applications in chemical biology and drug discovery.
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