Thu.Sep 26, 2024

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Bristol Myers schizophrenia drug, the first of its kind, approved by FDA

BioPharma Drive: Drug Pricing

In testing, Cobenfy eased schizophrenia symptoms without some of the disruptive side effects typical of existing drugs. The results have been met with excitement, as well as caution.

FDA 323
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These fish use legs to taste the seafloor

Science Daily: Pharmacology News

Sea robins are unusual animals with the body of a fish, wings of a bird, and walking legs of a crab. Now, researchers show that the legs of the sea robin aren't just used for walking. In fact, they are bona fide sensory organs used to find buried prey while digging.

Research 317
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Arch raises another $3B biotech fund in pursuit of ‘coolest’ new science

BioPharma Drive: Drug Pricing

Despite working in a restrictive funding climate, the prolific startup creator is “in the ‘taking lots of risk’ mode,” said co-founder and managing director Robert Nelsen.

Science 299
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'Weekend warrior' physical activity may help protect against more than 200 diseases

Science Daily: Pharmacology News

Compared with inactivity, a weekend warrior pattern of exercise (concentrating most moderate-to-vigorous physical activity in one to two days during the week) or a more evenly distributed physical activity pattern were associated with similarly lower risks of diseases across 16 categories -- from heart and digestive conditions to mental health and neurological illnesses.

Disease 314
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Trial Confirms 'Life-Changing' Impact of Gene Therapy, Beqvez, for Hemophilia B

Drugs.com

THURSDAY, Sept. 25, 2024 -- A new gene therapy approved earlier this year can serve as a sustainable single-dose treatment for people with hemophilia B, newly published clinical trial data shows. People with hemophilia B saw their bleeding episodes.

Therapies 290

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Gum Disease Germs Could Help Trigger Cancer

Drugs.com

THURSDAY, Sept. 26, 2024 -- Bacteria that causes gum disease can also raise a person’s risk of head and neck cancers, a new study says.More than a dozen bacterial species have been linked to a collective 50% increased risk of head and neck cancer, r.

Disease 278
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A method of 'look twice, forgive once' can sustain social cooperation

Science Daily: Pharmacology News

Using mathematical modeling, researchers found a way to maintain cooperation without relying on complex norms or institutions.

Research 312
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Pfizer to pull sickle cell drug from market, shut down trials

BioPharma Drive: Drug Pricing

The withdrawal comes as trial results indicate safety concerns with the drug, Oxbryta, which was first approved in the U.S. in 2019.

Trials 269
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This rocky planet around a white dwarf resembles Earth -- 8 billion years from now

Science Daily: Pharmacology News

A 2020 microlensing event was caused by a planetary system with an Earth-like planet and brown dwarf. The star type was uncertain. The team has determined that the star is a white dwarf, a system resembling what our sun-Earth system will look like in 8 billion years. The good news: the planet survived its star's red giant phase, so maybe Earth will too.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Most Pregnant Women Will Become Iron Deficient, Study Finds

Drugs.com

THURSDAY, Sept. 26, 2024 -- Four out of five pregnant women will become deficient in an essential nutrient, iron, by their third trimester, a new study finds.The researchers and other experts are now advocating that iron levels be routinely checked.

Research 263
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Scientists design new drug to fight malaria

Science Daily: Pharmacology News

A team has designed a new drug against malaria and identified its mechanism of action.

Drugs 302
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Forget BMI, 'Body Roundness' Measure Could Spot Heart Risk

Drugs.com

THURSDAY, Sept. 26, 2024 -- “Body roundness” could be a better measure than BMI at predicting how excess weight might affect a person’s heart health, a new study finds.People who developed a high Body Roundness Index during a six-year period had a 1.

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NASA's Hubble finds that a black hole beam promotes stellar eruptions

Science Daily: Pharmacology News

In a surprise finding, astronomers using NASA's Hubble Space Telescope have discovered that the blowtorch-like jet from a supermassive black hole at the core of a huge galaxy seems to cause stars to erupt along its trajectory. The stars, called novae, are not caught inside the jet, but apparently in a dangerous neighborhood nearby.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Health Concerns Around Fluoride in Water Merit EPA Action, Judge Rules

Drugs.com

THURSDAY, Sept. 26, 2024 -- -- The Environmental Protection Agency must address concerns about potential health risks posed by the recommended levels of fluoride in the country's drinking water, a federal court in California has ruled.While.

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Scientists uncover a critical component that helps killifish regenerate their fins

Science Daily: Pharmacology News

Spontaneous injuries like the loss of a limb or damage to the spinal cord are impossible for humans to repair. Yet, some animals have an extraordinary capacity to regenerate after injury, a response that requires a precise sequence of cellular events. Now, new research has unveiled a critical timing factor -- specifically how long cells actively respond to injury -- involved in regulating regeneration.

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Trial Confirms 'Life-Changing' Impact of Gene Therapy for Hemophilia B

Drugs.com

THURSDAY, Sept. 25, 2024 -- A new gene therapy approved earlier this year can serve as a sustainable single-dose treatment for people with hemophilia B, newly published clinical trial data shows.People with hemophilia B saw their bleeding episodes.

Therapies 246
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ESO telescope captures the most detailed infrared map ever of our Milky Way

Science Daily: Pharmacology News

Astronomers have published a gigantic infrared map of the Milky Way containing more than 1.5 billion objects -- the most detailed one ever made. Using the European Southern Observatory's VISTA telescope, the team monitored the central regions of our Galaxy over more than 13 years. At 500 terabytes of data, this is the largest observational project ever carried out with an ESO telescope.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Know What 'Chroming' Is? TikTok Fad Could Harm Your Kids

Drugs.com

FRIDAY, Sept. 27, 2024 -- Chroming, where toxic fumes from common household items are inhaled for a quick high, is on the rise among youth and TikTok may be to blame, new research suggests.In findings that are to be presented Saturday at the.

Research 246
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Peptide and Protein Cysteine Modification Enabled by Hydrosulfuration of Ynamide

Covalent Modifiers

Changliu Wang, Zhenguang Zhao, Reem Ghadir, Dechun Yang, Zhenjia Zhang, Zhe Ding, Yuan Cao, Yuqing Li, Rosi Fassler, Dana Reichmann, Yujie Zhang, Yongli Zhao, Can Liu, Xiaobao Bi, Norman Metanis, and Junfeng Zhao ACS Central Science 2024 10 (9), 1742-1754 DOI: 10.1021/acscentsci.4c01148 Efficient functionalization of peptides and proteins has widespread applications in chemical biology and drug discovery.

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U.S. Restarts Free COVID Test Program

Drugs.com

THURSDAY, Sept. 26, 2024 -- Starting today, the U.S. government is offering another round of free COVID tests."U.S. households will be eligible to order 4 free COVID-19 tests at COVIDTests.gov," according to the Department of Health and Human.

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Lawmakers call for investigation of former FDA device director

BioPharma Drive: Drug Pricing

The letter follows a New York Times report that raised concerns about Jeff Shuren’s potential conflicts of interest as head of the FDA’s device center.

FDA 130
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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U.S. Suicide Death Rate Is Rising Again

Drugs.com

THURSDAY, Sept. 26, 2024 -- U.S. suicide rates are ticking back upward again after a dip during the pandemic, new statistics show.Suicide deaths per 100,000 people had fallen from 14.2 recorded in the pre-pandemic year of 2018 to 13.5 in 2020.

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How to Conduct Effective Generic Drug Market Analysis

Drug Patent Watch

The generic drug market is a complex and dynamic environment where multiple factors influence the availability, quality, and pricing of generic drugs. Conducting an effective market analysis is crucial for pharmaceutical companies, policymakers, and healthcare professionals to understand the market dynamics and make informed decisions.

Marketing 105
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Being a 'Weekend Warrior' Can Cut Your Odds for 200 Diseases

Drugs.com

THURSDAY, Sept. 26, 2024 -- There’s good news for folks who struggle to fit regular exercise into their busy workweek.“Weekend warrior” workouts are just as beneficial as daily exercise to a person’s overall health, a new study says.People who get a.

Disease 246
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Powering the Future: Key Highlights from PPCC24 and What’s Next for Power Platform

Perficient: Drug Development

The energy was electric last week as thousands of attendees invaded MGM Grand along the Las Vegas Strip for the 3rd Annual Power Platform Community Conference (PPCC24). From groundbreaking announcements to new features unveiled during keynotes from Microsoft’s Charles Lamanna, Corporate Vice President of Business Industry and Copilot, and Jeff Teper, President of Apps and Platforms, PPCC24 offered an electrifying three days of innovation and collaboration.

Hospitals 105
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Brain Injury & PTSD: Veterans' Study Suggests Area of Damage Is Key

Drugs.com

THURSDAY, Sept. 26, 2024 -- Brain damage that veterans suffered from flying shrapnel has provided a major clue that could lead to better treatment for post-traumatic stress disorder (PTSD), a new study says.Veterans who suffered shrapnel damage.

Treatment 246